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V Arolt declares that over the last 3 years he has received compensations for his contributions as member of advisory boards and for presentations for the following companies: AstraZeneca, Eli Lilly, Janssen-Organon, Lundbeck, Otsuka, Servier and Trommsdorff. These co-operations have no relevance to the work that is covered in the manuscript. T Banaschewski served in an advisory or consultancy role for Hexal Pharma, Lilly, Medice, Novartis, Otsuka, Oxford outcomes, PCM scientific, Shire and Viforpharma. He received conference attendance support and conference support or received speaker\u2019s fees from Lilly, Medice, Novartis and Shire. He is\/has been involved in clinical trials conducted by Lilly, Shire & Viforpharma. F Bellivier has received honoraria or research or educational conference grants from Bristol-Myers Squibb, Otsuka, Eli Lilly, Servier, Takeda, Sanofi Aventis, Lundbeck, AstraZeneca, the European Space Agency and has received peer review research funding from French Ministry of research, Assistance Publique \u2013 H\u00f4pitaux de Paris, the National Institute for Research (INSERM) and the NARSAD. LJ Bierut, AM Goate and JC Wang are listed as inventors on Issued Us Patent 8\u2009080\u2009371, 'Markers for Addiction' covering the use of certain SNPs in determining the diagnosis, prognosis and treatment of addiction. NL Saccone is the spouse of SF Saccone, who is also listed as an inventor on the patent. JFW Deakin variously performed consultancy, speaking engagements and research for Bristol-Myers Squibb, AstraZeneca, Eli Lilly, Schering Plough, Janssen-Cilag and Servier (all fees are paid to the University of Manchester to reimburse them for the time taken); he has share options in P1vital. JI Nurnberger is an investigator for Assurex and Janssen and a consultant for Janssen. E Oli\u00e9 has received a research grant from AstraZeneca and speaking fees from Otsuka, AstraZeneca, Lundbeck. She is involved in clinical trail conducted by Janssen. The remaining authors declare no potential conflicts of interest: TM Air, KJ Anstey, R Araya, C \u00c5slund, G Bagdy, BT Baune, F Bellivier, DI Boomsma, L Bowes, M Burmeister, R Burns, EM Byrne, C Coffey, S Cohen-Woods, P Courtet, WF Coventry, RC Culverhouse, U Dannlowski, EJC de Geus, T Eley, S Easteal, B Etain, DM Fergusson, HL Fisher, K Gawronski, D Glei, N Goldman, X Gonda, HJ Grabe, S Guillaume, A Hatzimanolis, C Holzman, AC Horton, J Horwood, JJ Hottenga, I Jaussent, C Jawahar, C Jennen-Steinmetz, EO Johnson, G Juhasz, M Kennedy, JR Kramer, M Lajnef, M Laucht, KJ Lester, K Little, Y Ma, L Mandelli, NG Martin, CM Middeldorp, M Munaf\u00f2, M Nauck, E Nederhof, KW Nilsson, AJ Oldehinkel, C Olsson, J Ormel, C Otte, GC Patton, BWJH Penninx, P Petschner, WJ Peyrot, K Ritchie, M Sarchiapone, JM Scheid, C Schwahn, A Serretti, G Sinnamon, JH Smit, D Stacey, NC Stefanis, PG Surtees, Y Tian, C Toben, S Van der Auwera, S Villafuerte, H V\u00f6lzke, N Wainwright, M Weinstein, M Whooley, G Willemsen, HM zu Schwabedissen.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}