{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,8]],"date-time":"2025-02-08T05:27:37Z","timestamp":1738992457281,"version":"3.37.0"},"reference-count":14,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,10,7]],"date-time":"2016-10-07T00:00:00Z","timestamp":1475798400000},"content-version":"vor","delay-in-days":737,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Therapy"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1038\/mt.2014.169","type":"journal-article","created":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T05:15:37Z","timestamp":1412140537000},"page":"1724-1725","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Small-Molecule Therapies for Genetic Skin Fragility"],"prefix":"10.1016","volume":"22","author":[{"given":"Leena","family":"Bruckner-Tuderman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/mt.2014.169_bib1","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.jaad.2014.01.903","article-title":"The classification of inherited epidermolysis bullosa (EB): report of the Fourth International Consensus Meeting on Diagnosis and Classification of EB","volume":"70","author":"Fine","year":"2014","journal-title":"J Am Acad Dermatol"},{"key":"10.1038\/mt.2014.169_bib2","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1038\/jid.2013.127","article-title":"Progress in epidermolysis bullosa research: summary of DEBRA International Research Conference 2012","volume":"133","author":"Bruckner-Tuderman","year":"2013","journal-title":"J Invest Dermatol"},{"key":"10.1038\/mt.2014.169_bib3","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1038\/mt.2014.140","article-title":"Aminoglycosides restore full-length type VII collagen by overcoming premature termination codons: therapeutic implications for dystrophic epidermolysis bullosa","volume":"22","author":"Cogan","year":"2014","journal-title":"Mol Ther"},{"key":"10.1038\/mt.2014.169_bib4","doi-asserted-by":"crossref","first-page":"16.1","DOI":"10.1146\/annurev-genom-090413-025540","article-title":"The genetics of skin fragility","volume":"15","author":"Has","year":"2014","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"10.1038\/mt.2014.169_bib5","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1172\/JCI34292","article-title":"A hypomorphic mouse model for dystrophic epidermolysis bullosa reveals disease mechanisms and responds to fibroblast therapy","volume":"118","author":"Fritsch","year":"2008","journal-title":"J Clin Invest"},{"key":"10.1038\/mt.2014.169_bib6","doi-asserted-by":"crossref","first-page":"3498","DOI":"10.1172\/JCI68127","article-title":"Collagen VII plays a dual role in wound healing","volume":"123","author":"Nystr\u00f6m","year":"2013","journal-title":"J Clin Invest"},{"key":"10.1038\/mt.2014.169_bib7","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1172\/JCI7866","article-title":"Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice","volume":"104","author":"Barton-Davis","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1038\/mt.2014.169_bib8","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.molmed.2012.09.008","article-title":"Sense from nonsense: therapies for premature stop codon diseases","volume":"18","author":"Bidou","year":"2012","journal-title":"Trends Mol Med"},{"key":"10.1038\/mt.2014.169_bib9","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1096\/fj.13-240044","article-title":"Muscle dysfunction and structural defects of dystrophin-null sapje mutant zebrafish larvae are rescued by ataluren treatment","volume":"28","author":"Li","year":"2014","journal-title":"FASEB J"},{"key":"10.1038\/mt.2014.169_bib10","doi-asserted-by":"crossref","first-page":"19483","DOI":"10.1073\/pnas.1312088110","article-title":"Repair of UV photolesions in xeroderma pigmentosum group C cells induced by translational readthrough of premature termination codons","volume":"110","author":"Kuschal","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/mt.2014.169_bib11","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.tig.2003.11.004","article-title":"Collagens, modifying enzymes and their mutations in humans, flies and worms","volume":"20","author":"Myllyharju","year":"2004","journal-title":"Trends Genet"},{"key":"10.1038\/mt.2014.169_bib12","first-page":"2551","article-title":"Nonsense-mediated mRNA decay of collagen\u2014emerging complexity in RNA surveillance mechanisms","volume":"126","author":"Fang","year":"2013","journal-title":"J Cell Sci"},{"key":"10.1038\/mt.2014.169_bib13","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1146\/annurev-med-120611-144851","article-title":"Ataluren as an agent for therapeutic nonsense suppression","volume":"64","author":"Peltz","year":"2013","journal-title":"Annu Rev Med"},{"key":"10.1038\/mt.2014.169_bib14","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S2213-2600(14)70100-6","article-title":"Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial","volume":"2","author":"Kerem","year":"2014","journal-title":"Lancet Respir Med"}],"container-title":["Molecular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525001616307754?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525001616307754?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T17:20:01Z","timestamp":1738948801000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525001616307754"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":14,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["S1525001616307754"],"URL":"https:\/\/doi.org\/10.1038\/mt.2014.169","relation":{},"ISSN":["1525-0016"],"issn-type":[{"type":"print","value":"1525-0016"}],"subject":[],"published":{"date-parts":[[2014,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Small-Molecule Therapies for Genetic Skin Fragility","name":"articletitle","label":"Article Title"},{"value":"Molecular Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/mt.2014.169","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 The American Society of Gene & Cell Therapy. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}