{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T15:29:19Z","timestamp":1780586959287,"version":"3.54.1"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"7109","license":[{"start":{"date-parts":[[2006,9,20]],"date-time":"2006-09-20T00:00:00Z","timestamp":1158710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2006,9,20]],"date-time":"2006-09-20T00:00:00Z","timestamp":1158710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[2006,9,21]]},"DOI":"10.1038\/nature05218","type":"journal-article","created":{"date-parts":[[2006,9,20]],"date-time":"2006-09-20T17:45:31Z","timestamp":1158774331000},"page":"E5-E5","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Is IL2RG oncogenic in T-cell development?"],"prefix":"10.1038","volume":"443","author":[{"given":"Karin","family":"Pike-Overzet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dick","family":"de Ridder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Floor","family":"Weerkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miranda R. M.","family":"Baert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique M.","family":"Verstegen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martijn H.","family":"Brugman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Howe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel J. T.","family":"Reinders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian J.","family":"Thrasher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Wagemaker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques J. M.","family":"van Dongen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank J. T.","family":"Staal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,9,20]]},"reference":[{"key":"BFnature05218_CR1","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1038\/4401123a","volume":"440","author":"N-B Woods","year":"2006","unstructured":"Woods, N.-B., Bottero, V., Schmidt, M., von Kalle, C. & Verma, I. M. Nature 440, 1123 (2006).","journal-title":"Nature"},{"key":"BFnature05218_CR2","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1056\/NEJM200301163480314","volume":"348","author":"S Hacein-Bey-Abina","year":"2003","unstructured":"Hacein-Bey-Abina, S. et al. N. Engl. J. Med. 348, 255\u2013256 (2003).","journal-title":"N. Engl. J. Med."},{"key":"BFnature05218_CR3","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1126\/science.299.5605.320","volume":"299","author":"E Marshal","year":"2003","unstructured":"Marshal, E. Science 299, 320 (2003).","journal-title":"Science"},{"key":"BFnature05218_CR4","first-page":"561","volume":"433","author":"E Check","year":"2005","unstructured":"Check, E. Nature 433, 561 (2005).","journal-title":"Nature"},{"key":"BFnature05218_CR5","first-page":"415","volume":"302","author":"S Hacein-Bey-Abina","year":"2003","unstructured":"Hacein-Bey-Abina, S. et al. N. Engl. J. Med. 302, 415\u2013419 (2003).","journal-title":"N. Engl. J. Med."},{"key":"BFnature05218_CR6","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1084\/jem.20042524","volume":"201","author":"W Dik","year":"2005","unstructured":"Dik, W. et al. J. Exp. Med. 201, 1715\u20131723 (2005).","journal-title":"J. Exp. Med."},{"key":"BFnature05218_CR7","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.it.2006.01.006","volume":"27","author":"F Weerkamp","year":"2006","unstructured":"Weerkamp, F., Pike-Overzet, K., & Staal, F. J. T. Trends Immunol. 27, 125\u2013131 (2006).","journal-title":"Trends Immunol."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/nature05218.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/nature05218","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/nature05218.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T18:11:43Z","timestamp":1743703903000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nature05218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9,20]]},"references-count":7,"journal-issue":{"issue":"7109","published-print":{"date-parts":[[2006,9,21]]}},"alternative-id":["BFnature05218"],"URL":"https:\/\/doi.org\/10.1038\/nature05218","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9,20]]},"assertion":[{"value":"20 September 2006","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}