{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T01:11:22Z","timestamp":1792717882174,"version":"4.5.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"7494","license":[{"start":{"date-parts":[[2014,3,26]],"date-time":"2014-03-26T00:00:00Z","timestamp":1395792000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1038\/nature13165","type":"journal-article","created":{"date-parts":[[2014,3,26]],"date-time":"2014-03-26T06:46:27Z","timestamp":1395816387000},"page":"55-60","source":"Crossref","is-referenced-by-count":1843,"title":["Capillary pericytes regulate cerebral blood flow in health and disease"],"prefix":"10.1038","volume":"508","author":[{"given":"Catherine N.","family":"Hall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare","family":"Reynell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bodil","family":"Gesslein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola B.","family":"Hamilton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anusha","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad A.","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fergus M.","family":"O\u2019Farrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alastair M.","family":"Buchan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Lauritzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Attwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,3,26]]},"reference":[{"key":"BFnature13165_CR1","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/nature05193","volume":"443","author":"CM Peppiatt","year":"2006","unstructured":"Peppiatt, C. M., Howarth, C., Mobbs, P. & Attwell, D. Bidirectional control of CNS capillary diameter by pericytes. Nature 443, 700\u2013704 (2006)","journal-title":"Nature"},{"key":"BFnature13165_CR2","doi-asserted-by":"crossref","first-page":"22290","DOI":"10.1073\/pnas.1011321108","volume":"107","author":"F Fern\u00e1ndez-Klett","year":"2010","unstructured":"Fern\u00e1ndez-Klett, F., Offenhauser, N., Dirnagl, U., Priller, J. & Lindauer, U. Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain. Proc. Natl. Acad. Sci. USA 107, 22290\u201322295 (2010)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnature13165_CR3","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0002-9440(10)63389-5","volume":"165","author":"T Chan-Ling","year":"2004","unstructured":"Chan-Ling, T. et al. Desmin ensheathment ratio as an indicator of vessel stability: evidence in normal development and in retinopathy of prematurity. Am. J. Pathol. 165, 1301\u20131313 (2004)","journal-title":"Am. J. Pathol."},{"key":"BFnature13165_CR4","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.neuron.2010.09.043","volume":"68","author":"RD Bell","year":"2010","unstructured":"Bell, R. D. et al. Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging. Neuron 68, 409\u2013427 (2010)","journal-title":"Neuron"},{"key":"BFnature13165_CR5","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nature09522","volume":"468","author":"A Armulik","year":"2010","unstructured":"Armulik, A. et al. Pericytes regulate the blood\u2013brain barrier. Nature 468, 557\u2013561 (2010)","journal-title":"Nature"},{"key":"BFnature13165_CR6","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/nature09513","volume":"468","author":"R Daneman","year":"2010","unstructured":"Daneman, R., Zhou, L., Kebede, A. A. & Barres, B. A. Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature 468, 562\u2013566 (2010)","journal-title":"Nature"},{"key":"BFnature13165_CR7","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1126\/science.1203165","volume":"333","author":"C G\u00f6ritz","year":"2011","unstructured":"G\u00f6ritz, C. et al. A pericyte origin of spinal cord scar tissue. Science 333, 238\u2013242 (2011)","journal-title":"Science"},{"key":"BFnature13165_CR8","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1038\/sj.jcbfm.9600272","volume":"26","author":"P Dore-Duffy","year":"2006","unstructured":"Dore-Duffy, P., Katychev, A., Wang, X. & Van Buren, E. CNS microvascular pericytes exhibit multipotential stem cell activity. J. Cereb. Blood Flow Metab. 26, 613\u2013624 (2006)","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"BFnature13165_CR9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10739680601072099","volume":"14","author":"DG Puro","year":"2007","unstructured":"Puro, D. G. Physiology and pathobiology of the pericyte-containing retinal microvasculature: new developments. Microcirculation 14, 1\u201310 (2007)","journal-title":"Microcirculation"},{"key":"BFnature13165_CR10","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1161\/01.RES.75.1.55","volume":"75","author":"A Villringer","year":"1994","unstructured":"Villringer, A., Them, A., Lindauer, U., Einh\u00e4upl, K. & Dirnagl, U. Capillary perfusion of the rat brain cortex. An in vivo confocal microscopy study. Circ. Res. 75, 55\u201362 (1994)","journal-title":"Circ. Res."},{"key":"BFnature13165_CR11","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0006-8993(02)03848-9","volume":"963","author":"ML Schulte","year":"2003","unstructured":"Schulte, M. L., Wood, J. D. & Hudetz, A. G. Cortical electrical stimulation alters erythrocyte perfusion pattern in the cerebral capillary network of the rat. Brain Res. 963, 81\u201392 (2003)","journal-title":"Brain Res."},{"key":"BFnature13165_CR12","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/jcbfm.2011.153","volume":"32","author":"SN Jespersen","year":"2012","unstructured":"Jespersen, S. N. & \u00d8stergaard, L. The roles of cerebral blood flow, capillary transit time heterogeneity, and oxygen tension in brain oxygenation and metabolism. J. Cereb. Blood Flow Metab. 32, 264\u2013277 (2012)","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"BFnature13165_CR13","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/nature09613","volume":"468","author":"D Attwell","year":"2010","unstructured":"Attwell, D. et al. Glial and neuronal control of blood flow. Nature 468, 232\u2013243 (2010)","journal-title":"Nature"},{"key":"BFnature13165_CR14","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1038\/nm.2022","volume":"15","author":"M Yemisci","year":"2009","unstructured":"Yemisci, M. et al. Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. Nature Med. 15, 1031\u20131037 (2009)","journal-title":"Nature Med."},{"key":"BFnature13165_CR15","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1038\/nm0910-959","volume":"16","author":"GE Vates","year":"2010","unstructured":"Vates, G. E., Takano, T., Zlokovic, B. & Nedergaard, M. Pericyte constriction after stroke: the jury is still out. Nature Med. 16, 959 (2010)","journal-title":"Nature Med."},{"key":"BFnature13165_CR16","doi-asserted-by":"crossref","first-page":"8940","DOI":"10.1523\/JNEUROSCI.0026-12.2012","volume":"32","author":"CN Hall","year":"2012","unstructured":"Hall, C. N., Klein-Fl\u00fcgge, M. C., Howarth, C. & Attwell, D. Oxidative phosphorylation, not glycolysis, powers presynaptic and postsynaptic mechanisms underlying brain information processing. J. Neurosci. 32, 8940\u20138951 (2012)","journal-title":"J. Neurosci."},{"key":"BFnature13165_CR17","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.1113\/jphysiol.2008.154724","volume":"586","author":"CN Hall","year":"2008","unstructured":"Hall, C. N. & Attwell, D. Assessing the physiological concentration and targets of nitric oxide in brain tissue. J. Physiol. (Lond.) 586, 3597\u20133615 (2008)","journal-title":"J. Physiol. (Lond.)"},{"key":"BFnature13165_CR18","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1242\/dev.004895","volume":"135","author":"X Zhu","year":"2008","unstructured":"Zhu, X., Bergles, D. E. & Nishiyama, A. NG2 cells generate both oligodendrocytes and gray matter astrocytes. Development 135, 145\u2013157 (2008)","journal-title":"Development"},{"key":"BFnature13165_CR19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/glia.20898","volume":"58","author":"M Krueger","year":"2010","unstructured":"Krueger, M. & Bechmann, I. CNS pericytes: concepts, misconceptions, and a way out. Glia 58, 1\u201310 (2010)","journal-title":"Glia"},{"key":"BFnature13165_CR20","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3389\/fnene.2010.00005","volume":"2","author":"NB Hamilton","year":"2010","unstructured":"Hamilton, N. B., Attwell, D. & Hall, C. N. Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease. Front. Neuroenergetics 2, 5 (2010)","journal-title":"Front. Neuroenergetics"},{"key":"BFnature13165_CR21","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0090-6980(94)90053-1","volume":"47","author":"V Serebryakov","year":"1994","unstructured":"Serebryakov, V., Zakharenko, S., Snetkov, V. & Takeda, K. Effects of prostaglandins E1 and E2 on cultured smooth muscle cells and strips of rat aorta. Prostaglandins 47, 353\u2013365 (1994)","journal-title":"Prostaglandins"},{"key":"BFnature13165_CR22","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1159\/000339110","volume":"120","author":"C Crawford","year":"2012","unstructured":"Crawford, C. et al. An intact kidney slice model to investigate vasa recta properties and function in situ. Nephron Physiol. 120, 17\u201331 (2012)","journal-title":"Nephron Physiol."},{"key":"BFnature13165_CR23","doi-asserted-by":"crossref","first-page":"15741","DOI":"10.1073\/pnas.95.26.15741","volume":"95","author":"D Kleinfeld","year":"1998","unstructured":"Kleinfeld, D., Mitra, P. P., Helmchen, F. & Denk, W. Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex. Proc. Natl. Acad. Sci. USA 95, 15741\u201315746 (1998)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnature13165_CR24","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1212\/WNL.0b013e3181b9c847","volume":"73","author":"P Khatri","year":"2009","unstructured":"Khatri, P. et al. Good clinical outcome after ischemic stroke with successful revascularization is time-dependent. Neurology 73, 1066\u20131072 (2009)","journal-title":"Neurology"},{"key":"BFnature13165_CR25","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1136\/neurintsurg-2011-010245","volume":"5","author":"E Gupta","year":"2013","unstructured":"Gupta, E. et al. Higher volume endovascular stroke centers have faster times to treatment, higher reperfusion rates and higher rates of good clinical outcomes. J. Neurointerv. Surg. 5, 294\u2013297 (2013)","journal-title":"J. Neurointerv. Surg."},{"key":"BFnature13165_CR26","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/00004647-200404000-00003","volume":"24","author":"EF Hauck","year":"2004","unstructured":"Hauck, E. F., Apostel, S., Hoffmann, J. F., Heimann, A. & Kempski, O. Capillary flow and diameter changes during reperfusion after global cerebral ischemia studied by intravital video microscopy. J. Cereb. Blood Flow Metab. 24, 383\u2013391 (2004)","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"BFnature13165_CR27","first-page":"H266","volume":"257","author":"CW Leffler","year":"1989","unstructured":"Leffler, C. W., Beasley, D. G. & Busija, D. W. Cerebral ischemia alters cerebral microvascular reactivity in newborn pigs. Am. J. Physiol. 257, H266\u2013H271 (1989)","journal-title":"Am. J. Physiol."},{"key":"BFnature13165_CR28","first-page":"H1356","volume":"263","author":"CW Nelson","year":"1992","unstructured":"Nelson, C. W., Wei, E. P., Povlishock, J. T., Kontos, H. A. & Moskowitz, M. A. Oxygen radicals in cerebral ischemia. Am. J. Physiol. 263, H1356\u2013H1362 (1992)","journal-title":"Am. J. Physiol."},{"key":"BFnature13165_CR29","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1161\/01.STR.25.1.79","volume":"25","author":"AE Baird","year":"1994","unstructured":"Baird, A. E. et al. Reperfusion after thrombolytic therapy in ischemic stroke measured by single-photon emission computed tomography. Stroke 25, 79\u201385 (1994)","journal-title":"Stroke"},{"key":"BFnature13165_CR30","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/S0166-2236(02)02264-6","volume":"25","author":"D Attwell","year":"2002","unstructured":"Attwell, D. & Iadecola, C. The neural basis of functional imaging signals. Trends Neurosci. 25, 621\u2013625 (2002)","journal-title":"Trends Neurosci."},{"key":"BFnature13165_CR31","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0306-4522(98)00737-4","volume":"92","author":"TA Lovick","year":"1999","unstructured":"Lovick, T. A., Brown, L. A. & Kay, B. J. Neurovascular relationships in hippocampal slices: physiological and anatomical studies of mechanisms underlying flow-metabolism coupling in intraparenchymal microvessels. Neuroscience 92, 47\u201360 (1999)","journal-title":"Neuroscience"},{"key":"BFnature13165_CR32","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1097\/00004647-199708000-00008","volume":"17","author":"Z Cohen","year":"1997","unstructured":"Cohen, Z., Molinatti, G. & Hamel, E. Astroglial and vascular interactions of noradrenaline terminals in the rat cerebral cortex. J. Cereb. Blood Flow Metab. 17, 894\u2013904 (1997)","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"BFnature13165_CR33","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1038\/nn.3426","volume":"16","author":"P Blinder","year":"2013","unstructured":"Blinder, P. et al. The cortical angiome: a 3-D interconnected vascular network with noncolumnar patterns of blood flow. Nature Neurosci. 16, 889\u2013897 (2013)","journal-title":"Nature Neurosci."},{"key":"BFnature13165_CR34","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1038\/jcbfm.2012.175","volume":"33","author":"C Mathiesen","year":"2013","unstructured":"Mathiesen, C., Brazhe, A., Thomsen, K. & Lauritzen, M. Spontaneous calcium waves in Bergmann glia increase with age and hypoxia and may reduce tissue oxygen. J. Cereb. Blood Flow Metab. 33, 161\u2013169 (2013)","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"BFnature13165_CR35","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/nn1458","volume":"8","author":"P Marcaggi","year":"2005","unstructured":"Marcaggi, P. & Attwell, D. Endocannabinoid signaling depends on the spatial pattern of synapse activation. Nature Neurosci. 8, 776\u2013781 (2005)","journal-title":"Nature Neurosci."},{"key":"BFnature13165_CR36","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0014-4827(79)90392-6","volume":"120","author":"BP Peters","year":"1979","unstructured":"Peters, B. P. & Goldstein, I. J. The use of fluorescein-conjugated Bandeiraea simplicifolia B4-isolectin as a histochemical reagent for the detection of alpha-D-galactopyranosyl groups. Their occurrence in basement membranes. Exp. Cell Res. 120, 321\u2013334 (1979)","journal-title":"Exp. Cell Res."},{"key":"BFnature13165_CR37","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/BF01680633","volume":"19","author":"L Laitinen","year":"1987","unstructured":"Laitinen, L. Griffonia simplicifolia lectins bind specifically to endothelial cells and some epithelial cells in mouse tissues. Histochem. J. 19, 225\u2013234 (1987)","journal-title":"Histochem. J."},{"key":"BFnature13165_CR38","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1111\/j.1469-7793.2001.00773.x","volume":"533","author":"A Norup Nielsen","year":"2001","unstructured":"Norup Nielsen, A. & Lauritzen, M. Coupling and uncoupling of activity-dependent increases of neuronal activity and blood flow in rat somatosensory cortex. J. Physiol. (Lond.) 533, 773\u2013785 (2001)","journal-title":"J. Physiol. (Lond.)"},{"key":"BFnature13165_CR39","doi-asserted-by":"crossref","first-page":"6082","DOI":"10.1073\/pnas.87.16.6082","volume":"87","author":"RD Frostig","year":"1990","unstructured":"Frostig, R. D., Lieke, E. E., Ts'o, D. Y. & Grinvald, A. Cortical functional architecture and local coupling between neuronal activity and the microcirculation revealed by in vivo high-resolution optical imaging of intrinsic signals. Proc. Natl. Acad. Sci. USA 87, 6082\u20136086 (1990)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnature13165_CR40","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jneumeth.2009.06.021","volume":"182","author":"TC Harrison","year":"2009","unstructured":"Harrison, T. C., Sigler, A. & Murphy, T. H. Simple and cost-effective hardware and software for functional brain mapping using intrinsic optical signal imaging. J. Neurosci. Methods 182, 211\u2013218 (2009)","journal-title":"J. Neurosci. Methods"},{"key":"BFnature13165_CR41","doi-asserted-by":"crossref","first-page":"e22","DOI":"10.1371\/journal.pbio.0040022","volume":"4","author":"CB Schaffer","year":"2006","unstructured":"Schaffer, C. B. et al. Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion. PLoS Biol. 4, e22 (2006)","journal-title":"PLoS Biol."},{"key":"BFnature13165_CR42","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1523\/JNEUROSCI.4157-04.2005","volume":"25","author":"NJ Allen","year":"2005","unstructured":"Allen, N. J., K\u00e1rad\u00f3ttir, R. & Attwell, D. A preferential role for glycolysis in preventing the anoxic depolarization of rat hippocampal area CA1 pyramidal cells. J. Neurosci. 25, 848\u2013859 (2005)","journal-title":"J. Neurosci."},{"key":"BFnature13165_CR43","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1006\/mvre.2000.2244","volume":"60","author":"P Dore-Duffy","year":"2000","unstructured":"Dore-Duffy, P. et al. Pericyte migration from the vascular wall in response to traumatic brain injury. Microvasc. Res. 60, 55\u201369 (2000)","journal-title":"Microvasc. Res."},{"key":"BFnature13165_CR44","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1006\/mvre.2002.2413","volume":"64","author":"E Gonul","year":"2002","unstructured":"Gonul, E. et al. Early pericyte response to brain hypoxia in cats: an ultrastructural study. Microvasc. Res. 64, 116\u2013119 (2002)","journal-title":"Microvasc. Res."},{"key":"BFnature13165_CR45","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/jcbfm.2010.60","volume":"31","author":"S Nagel","year":"2011","unstructured":"Nagel, S. et al. Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 31, 132\u2013143 (2011)","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"BFnature13165_CR46","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1161\/01.STR.26.4.627","volume":"26","author":"JH Garcia","year":"1995","unstructured":"Garcia, J. H., Wagner, S., Liu, K. F. & Hu, X. J. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke 26, 627\u2013635 (1995)","journal-title":"Stroke"},{"key":"BFnature13165_CR47","doi-asserted-by":"crossref","first-page":"556","DOI":"10.3109\/13550289909021285","volume":"5","author":"WM Pardridge","year":"1999","unstructured":"Pardridge, W. M. Blood-brain barrier biology and methodology. J. Neurovirol. 5, 556\u2013569 (1999)","journal-title":"J. Neurovirol."},{"key":"BFnature13165_CR48","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1152\/jn.1997.78.2.651","volume":"78","author":"C Iadecola","year":"1997","unstructured":"Iadecola, C., Yang, G., Ebner, T. J. & Chen, G. Local and propagated responses evoked by focal synaptic activity in cerebellar cortex. J. Neurophysiol. 78, 651\u2013659 (1997)","journal-title":"J. Neurophysiol."},{"key":"BFnature13165_CR49","doi-asserted-by":"crossref","first-page":"12670","DOI":"10.1073\/pnas.1007239107","volume":"107","author":"P Blinder","year":"2010","unstructured":"Blinder, P., Shih, A. Y., Rafie, C. & Kleinfeld, D. Topological basis for the robust distribution of blood to rodent neocortex. Proc. Natl. Acad. Sci. USA 107, 12670\u201312675 (2010)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnature13165_CR50","first-page":"H1223","volume":"264","author":"U Lindauer","year":"1993","unstructured":"Lindauer, U., Villringer, A. & Dirnagl, U. Characterization of CBF response to somatosensory stimulation: model and influence of anesthetics. Am. J. Physiol. 264, H1223\u2013H1228 (1993)","journal-title":"Am. J. Physiol."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nature13165.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nature13165","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nature13165.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T14:20:10Z","timestamp":1684419610000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nature13165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,26]]},"references-count":50,"journal-issue":{"issue":"7494","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["BFnature13165"],"URL":"https:\/\/doi.org\/10.1038\/nature13165","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718326501.793493340","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.718326501.793493246","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.718326501.793493237","asserted-by":"object"}]},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,26]]}}}