{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T02:07:37Z","timestamp":1792721257890,"version":"4.5.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"7563","license":[{"start":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T00:00:00Z","timestamp":1435104000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"},{"start":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T00:00:00Z","timestamp":1435104000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[2015,8,6]]},"DOI":"10.1038\/nature14612","type":"journal-article","created":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T20:22:26Z","timestamp":1435177346000},"page":"102-104","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":100,"title":["Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic"],"prefix":"10.1038","volume":"524","author":[{"given":"Etienne","family":"Simon-Loriere","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ousmane","family":"Faye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oumar","family":"Faye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamine","family":"Koivogui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nfaly","family":"Magassouba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakoba","family":"Keita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Michel","family":"Thiberge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Diancourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Bouchier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Vandenbogaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Caro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamou","family":"Fall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan P.","family":"Buchmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christan B.","family":"Matranga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pardis C.","family":"Sabeti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Manuguerra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward C.","family":"Holmes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amadou A.","family":"Sall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,6,24]]},"reference":[{"key":"BFnature14612_CR1","unstructured":"The World Health Organization http:\/\/www.who.int\/csr\/don\/archive\/disease\/ebola\/en\/ (2014)"},{"key":"BFnature14612_CR2","doi-asserted-by":"publisher","first-page":"1418","DOI":"10.1056\/NEJMoa1404505","volume":"371","author":"S Baize","year":"2014","unstructured":"Baize, S. et al. Emergence of Zaire Ebola virus disease in Guinea. N. Engl. J. Med. 371, 1418\u20131425 (2014)","journal-title":"N. Engl. J. Med."},{"key":"BFnature14612_CR3","doi-asserted-by":"publisher","first-page":"17","DOI":"10.15252\/emmm.201404792","volume":"7","author":"A Mar\u00ed Sa\u00e9z","year":"2015","unstructured":"Mar\u00ed Sa\u00e9z, A. et al. Investigating the zoonotic origin of the West African Ebola epidemic. EMBO Mol. Med. 7, 17\u201323 (2015)","journal-title":"EMBO Mol. Med."},{"key":"BFnature14612_CR4","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1126\/science.1259657","volume":"345","author":"SK Gire","year":"2014","unstructured":"Gire, S. K. et al. Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science 345, 1369\u20131372 (2014)","journal-title":"Science"},{"key":"BFnature14612_CR5","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/S1473-3099(14)71075-8","volume":"15","author":"O Faye","year":"2015","unstructured":"Faye, O. et al. Chains of transmission and control of Ebola virus disease in Conakry, Guinea, in 2014: an observational study. Lancet Infect. Dis. 15, 320\u2013326 (2015)","journal-title":"Lancet Infect. Dis."},{"key":"BFnature14612_CR6","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1038\/nm.2202","volume":"16","author":"TK Warren","year":"2010","unstructured":"Warren, T. K. et al. Advanced antisense therapies for postexposure protection against lethal filovirus infections. Nature Med. 16, 991\u2013994 (2010)","journal-title":"Nature Med."},{"key":"BFnature14612_CR7","doi-asserted-by":"crossref","unstructured":"Kugelman, J. R. et al. Evaluation of the potential impact of Ebola virus genomic drift on the efficacy of sequence-based candidate therapeutics. MBio 6, (2015)","DOI":"10.1128\/mBio.02227-14"},{"key":"BFnature14612_CR8","doi-asserted-by":"publisher","first-page":"g5161","DOI":"10.1136\/bmj.g5161","volume":"349","author":"A Sayburn","year":"2014","unstructured":"Sayburn, A. WHO gives go ahead for experimental treatments to be used in Ebola outbreak. Br. Med. J. 349, g5161 (2014)","journal-title":"Br. Med. J."},{"key":"BFnature14612_CR9","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1126\/science.aaa5646","volume":"348","author":"T Hoenen","year":"2015","unstructured":"Hoenen, T. et al. Mutation rate and genotype variation of Ebola virus from Mali case sequences. Science 348, 117\u2013119 (2015)","journal-title":"Science"},{"key":"BFnature14612_CR10","doi-asserted-by":"publisher","first-page":"20140732","DOI":"10.1098\/rspb.2014.0732","volume":"281","author":"S Duch\u00eane","year":"2014","unstructured":"Duch\u00eane, S., Holmes, E. C. & Ho, S. Y. Analyses of evolutionary dynamics in viruses are hindered by a time-dependent bias in rate estimates. Proc. R. Soc. B 281, 20140732 (2014)","journal-title":"Proc. R. Soc. B"},{"key":"BFnature14612_CR11","doi-asserted-by":"publisher","first-page":"e90","DOI":"10.1371\/journal.ppat.0020090","volume":"2","author":"R Biek","year":"2006","unstructured":"Biek, R., Walsh, P. D., Leroy, E. M. & Real, L. A. Recent common ancestry of Ebola Zaire virus found in a bat reservoir. PLoS Pathog. 2, e90 (2006)","journal-title":"PLoS Pathog."},{"key":"BFnature14612_CR12","doi-asserted-by":"publisher","first-page":"2608","DOI":"10.1128\/JVI.03118-12","volume":"87","author":"SA Carroll","year":"2013","unstructured":"Carroll, S. A. et al. Molecular evolution of viruses of the family Filoviridae based on 97 whole-genome sequences. J. Virol. 87, 2608\u20132616 (2013)","journal-title":"J. Virol."},{"key":"BFnature14612_CR13","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.meegid.2014.10.028","volume":"29","author":"CA Devaux","year":"2015","unstructured":"Devaux, C. A. The hidden face of academic researches on classified highly pathogenic microorganisms. Infect. Genet. Evol. 29, 26\u201334 (2015)","journal-title":"Infect. Genet. Evol."},{"key":"BFnature14612_CR14","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1186\/s13059-014-0519-7","volume":"15","author":"CB Matranga","year":"2014","unstructured":"Matranga, C. B. et al. Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples. Genome Biol. 15, 519 (2014)","journal-title":"Genome Biol."},{"key":"BFnature14612_CR15","doi-asserted-by":"crossref","unstructured":"Blankenberg, D. et al. Galaxy: a web-based genome analysis tool for experimentalists. Curr. Protocols Mol. Biol. (2010)","DOI":"10.1002\/0471142727.mb1910s89"},{"key":"BFnature14612_CR16","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1101\/gr.4086505","volume":"15","author":"B Giardine","year":"2005","unstructured":"Giardine, B. et al. Galaxy: a platform for interactive large-scale genome analysis. Genome Res. 15, 1451\u20131455 (2005)","journal-title":"Genome Res."},{"key":"BFnature14612_CR17","doi-asserted-by":"publisher","first-page":"R86","DOI":"10.1186\/gb-2010-11-8-r86","volume":"11","author":"J Goecks","year":"2010","unstructured":"Goecks, J., Nekrutenko, A. & Taylor, J. Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences. Genome Biol. 11, R86 (2010)","journal-title":"Genome Biol."},{"key":"BFnature14612_CR18","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1093\/bioinformatics\/bts199","volume":"28","author":"M Kearse","year":"2012","unstructured":"Kearse, M. et al. Geneious Basic: an integrated and extendable desktop software platform for the organization and analysis of sequence data. Bioinformatics 28, 1647\u20131649 (2012)","journal-title":"Bioinformatics"},{"key":"BFnature14612_CR19","doi-asserted-by":"publisher","first-page":"1792","DOI":"10.1093\/nar\/gkh340","volume":"32","author":"RC Edgar","year":"2004","unstructured":"Edgar, R. C. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res. 32, 1792\u20131797 (2004)","journal-title":"Nucleic Acids Res."},{"key":"BFnature14612_CR20","doi-asserted-by":"publisher","first-page":"2462","DOI":"10.1093\/bioinformatics\/btq467","volume":"26","author":"DP Martin","year":"2010","unstructured":"Martin, D. P. et al. RDP3: a flexible and fast computer program for analyzing recombination. Bioinformatics 26, 2462\u20132463 (2010)","journal-title":"Bioinformatics"},{"key":"BFnature14612_CR21","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1093\/sysbio\/syq010","volume":"59","author":"S Guindon","year":"2010","unstructured":"Guindon, S. et al. New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst. Biol. 59, 307\u2013321 (2010)","journal-title":"Syst. Biol."},{"key":"BFnature14612_CR22","doi-asserted-by":"publisher","first-page":"1969","DOI":"10.1093\/molbev\/mss075","volume":"29","author":"AJ Drummond","year":"2012","unstructured":"Drummond, A. J., Suchard, M. A., Xie, D. & Rambaut, A. Bayesian phylogenetics with BEAUti and the BEAST 1.7. Mol. Biol. Evol. 29, 1969\u20131973 (2012)","journal-title":"Mol. Biol. Evol."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/nature14612.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/nature14612","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/nature14612.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T04:06:37Z","timestamp":1695096397000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nature14612"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,24]]},"references-count":22,"journal-issue":{"issue":"7563","published-print":{"date-parts":[[2015,8,6]]}},"alternative-id":["BFnature14612"],"URL":"https:\/\/doi.org\/10.1038\/nature14612","relation":{},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,24]]},"assertion":[{"value":"15 April 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 June 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 June 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}