{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:21:15Z","timestamp":1787678475449,"version":"build-2784847793"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T00:00:00Z","timestamp":1488153600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T00:00:00Z","timestamp":1488153600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Biotechnol"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1038\/nbt.3812","type":"journal-article","created":{"date-parts":[[2017,2,28]],"date-time":"2017-02-28T15:14:10Z","timestamp":1488294850000},"page":"193-197","source":"Crossref","is-referenced-by-count":34,"title":["The 'anti-hype' vaccine"],"prefix":"10.1038","volume":"35","author":[{"given":"Laura","family":"DeFrancesco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,2,27]]},"reference":[{"key":"BFnbt3812_CR1","doi-asserted-by":"publisher","first-page":"e52","DOI":"10.1038\/emi.2013.54","volume":"2","author":"A Hekele","year":"2013","unstructured":"Hekele, A. et al. Emerg. Microbes Infect. 2, e52 (2013).","journal-title":"Emerg. Microbes Infect."},{"key":"BFnbt3812_CR2","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/1471-2199-9-90","volume":"9","author":"IY Tcherepanova","year":"2008","unstructured":"Tcherepanova, I.Y. et al. BMC Mol. Biol. 9, 9 (2008).","journal-title":"BMC Mol. Biol."},{"key":"BFnbt3812_CR3","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1126\/science.1690918","volume":"247","author":"JA Wolff","year":"1990","unstructured":"Wolff, J.A. et al. Science 247, 1465\u20131468 (1990).","journal-title":"Science"},{"key":"BFnbt3812_CR4","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1038\/nrd4278","volume":"13","author":"U Sahin","year":"2014","unstructured":"Sahin, U., Karik\u00f3, K. & T\u00fcreci, \u00d6. Nat. Rev. Drug Discov. 13, 759\u2013780 (2014).","journal-title":"Nat. Rev. Drug Discov."},{"key":"BFnbt3812_CR5","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.immuni.2005.06.008","volume":"23","author":"K Karik\u00f3","year":"2005","unstructured":"Karik\u00f3, K., Buckstein, M., Ni, H. & Weissman, D. Immunity 23, 165\u2013175 (2005).","journal-title":"Immunity"},{"key":"BFnbt3812_CR6","doi-asserted-by":"publisher","first-page":"1833","DOI":"10.1038\/mt.2008.200","volume":"16","author":"K Karik\u00f3","year":"2008","unstructured":"Karik\u00f3, K. et al. Mol. Ther. 16, 1833\u20131840 (2008).","journal-title":"Mol. Ther."},{"key":"BFnbt3812_CR7","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/j.stem.2010.08.012","volume":"7","author":"L Warren","year":"2010","unstructured":"Warren, L. et al. Cell Stem Cell 7, 618\u2013630 (2010).","journal-title":"Cell Stem Cell"},{"key":"BFnbt3812_CR8","doi-asserted-by":"publisher","first-page":"1510","DOI":"10.1016\/0264-410X(94)90074-4","volume":"12","author":"X Zhou","year":"1994","unstructured":"Zhou, X. et al. Vaccine 12, 1510\u20131514 (1994).","journal-title":"Vaccine"},{"key":"BFnbt3812_CR9","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1038\/nsmb.2739","volume":"21","author":"EP Ricci","year":"2014","unstructured":"Ricci, E.P. et al. Nat. Struct. Mol. Biol. 21, 26\u201335 (2014).","journal-title":"Nat. Struct. Mol. Biol."},{"key":"BFnbt3812_CR10","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1038\/nmeth.3320","volume":"12","author":"PJ Santangelo","year":"2015","unstructured":"Santangelo, P.J. et al. Nat. Methods 12, 427\u2013432 (2015).","journal-title":"Nat. Methods"},{"key":"BFnbt3812_CR11","doi-asserted-by":"publisher","first-page":"14604","DOI":"10.1073\/pnas.1209367109","volume":"109","author":"AJ Geall","year":"2012","unstructured":"Geall, A.J. et al. Proc. Natl. Acad. Sci. USA 109, 14604\u201314609 (2012).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnbt3812_CR12","doi-asserted-by":"publisher","first-page":"2118","DOI":"10.1038\/mt.2014.133","volume":"22","author":"LA Brito","year":"2014","unstructured":"Brito, L.A. et al. Mol. Ther. 22, 2118\u20132129 (2014).","journal-title":"Mol. Ther."},{"key":"BFnbt3812_CR13","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1038\/nature18300","volume":"534","author":"LM Kranz","year":"2016","unstructured":"Kranz, L.M. et al. Nature 534, 396\u2013401 (2016).","journal-title":"Nature"},{"key":"BFnbt3812_CR14","doi-asserted-by":"publisher","first-page":"E4133","DOI":"10.1073\/pnas.1600299113","volume":"113","author":"JS Chahal","year":"2016","unstructured":"Chahal, J.S. et al. Proc. Natl. Acad. Sci. USA 113, E4133\u2013E4142 (2016).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnbt3812_CR15","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1172\/JCI0214364","volume":"109","author":"A Heiser","year":"2002","unstructured":"Heiser, A. et al. J. Clin. Invest. 109, 409\u2013417 (2002).","journal-title":"J. Clin. Invest."},{"key":"BFnbt3812_CR16","doi-asserted-by":"publisher","first-page":"2470","DOI":"10.1038\/bjc.2013.236","volume":"108","author":"RJ Motzer","year":"2013","unstructured":"Motzer, R.J. et al. Br. J. Cancer 108, 2470\u20132477 (2013).","journal-title":"Br. J. Cancer"},{"key":"BFnbt3812_CR17","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1097\/CJI.0b013e3181a00068","volume":"32","author":"B Weide","year":"2009","unstructured":"Weide, B. et al. J. Immunother. 32, 498\u2013507 (2009).","journal-title":"J. Immunother."},{"key":"BFnbt3812_CR18","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/s40425-015-0068-y","volume":"3","author":"H K\u00fcbler","year":"2015","unstructured":"K\u00fcbler, H. et al. J. Immunother. Cancer 3, 26 (2015).","journal-title":"J. Immunother. Cancer"},{"key":"BFnbt3812_CR19","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/978-1-4939-6481-9_14","volume":"1499","author":"M Diken","year":"2017","unstructured":"Diken, M. et al. Methods Mol. Biol. 1499, 223\u2013236 (2017).","journal-title":"Methods Mol. Biol."},{"key":"BFnbt3812_CR20","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1038\/nature14426","volume":"520","author":"S Kreiter","year":"2015","unstructured":"Kreiter, S. et al. Nature 520, 692\u2013696 (2015).","journal-title":"Nature"},{"key":"BFnbt3812_CR21","doi-asserted-by":"publisher","unstructured":"Pardi, N. et al. Nature http:\/\/dx.doi.org\/10.1038\/nature21428 (2017).","DOI":"10.1038\/nature21428"}],"container-title":["Nature Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/nbt.3812.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/nbt.3812","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/nbt.3812.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T22:28:01Z","timestamp":1733956081000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nbt.3812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,27]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["BFnbt3812"],"URL":"https:\/\/doi.org\/10.1038\/nbt.3812","relation":{},"ISSN":["1087-0156","1546-1696"],"issn-type":[{"value":"1087-0156","type":"print"},{"value":"1546-1696","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,27]]}}}