{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:02:56Z","timestamp":1791306176689,"version":"4.3.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2006,6,11]],"date-time":"2006-06-11T00:00:00Z","timestamp":1149984000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Cell Biol"],"published-print":{"date-parts":[[2006,7]]},"DOI":"10.1038\/ncb1432","type":"journal-article","created":{"date-parts":[[2006,6,11]],"date-time":"2006-06-11T17:28:02Z","timestamp":1150046882000},"page":"717-724","source":"Crossref","is-referenced-by-count":71,"title":["The retroviral oncoprotein Tax targets the coiled-coil centrosomal protein TAX1BP2 to induce centrosome overduplication"],"prefix":"10.1038","volume":"8","author":[{"given":"Yick-Pang","family":"Ching","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shing-Fai","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuan-Teh","family":"Jeang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Yan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,6,11]]},"reference":[{"key":"BFncb1432_CR1","doi-asserted-by":"publisher","first-page":"6146","DOI":"10.1038\/sj.onc.1205772","volume":"21","author":"AB D'Assoro","year":"2002","unstructured":"D'Assoro, A. B., Lingle, W. L. & Salisbury, J. L. Centrosome amplification and the development of cancer. Oncogene 21, 6146\u20136153 (2002).","journal-title":"Oncogene"},{"key":"BFncb1432_CR2","first-page":"3974","volume":"58","author":"GA Pihan","year":"1998","unstructured":"Pihan G. A. et al. Centrosome defects and genetic instability in malignant tumors. Cancer Res. 58, 3974\u20133985 (1998).","journal-title":"Cancer Res."},{"key":"BFncb1432_CR3","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1038\/sj.leu.2403780","volume":"19","author":"A Kramer","year":"2005","unstructured":"Kramer, A. Centrosome aberrations \u2014 hen or egg in cancer initiation and progression? Leukemia 19, 1142\u20131144 (2005).","journal-title":"Leukemia"},{"key":"BFncb1432_CR4","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/1742-4690-2-17","volume":"2","author":"RC Gallo","year":"2005","unstructured":"Gallo, R. C. The discovery of the first human retrovirus: HTLV-1 and HTLV-2. Retrovirology 2, 17 (2005).","journal-title":"Retrovirology"},{"key":"BFncb1432_CR5","doi-asserted-by":"publisher","first-page":"31991","DOI":"10.1074\/jbc.R400009200","volume":"279","author":"K-T Jeang","year":"2004","unstructured":"Jeang, K.-T., Giam, C.-z., Majone, F. & Aboud, M. Life, death, and Tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation. J. Biol. Chem. 279, 31991\u201331994 (2004).","journal-title":"J. Biol. Chem."},{"key":"BFncb1432_CR6","doi-asserted-by":"publisher","first-page":"4467","DOI":"10.1158\/0008-5472.CAN-05-0559","volume":"65","author":"M Matsuoka","year":"2005","unstructured":"Matsuoka, M. & Jeang, K.-T. Human T-cell leukemia virus type I at age 25: a progress report. Cancer Res. 65, 4467\u20134470 (2005).","journal-title":"Cancer Res."},{"key":"BFncb1432_CR7","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1146\/annurev.cellbio.21.122303.120418","volume":"21","author":"S Doxsey","year":"2005","unstructured":"Doxsey, S., McCollum, D. & Theurkauf, W. Centrosomes in cellular regulation. Annu. Rev. Cell Dev. Biol. 21, 411\u2013434 (2005).","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"BFncb1432_CR8","doi-asserted-by":"publisher","first-page":"5141","DOI":"10.1038\/sj.onc.1206549","volume":"22","author":"ML Gatza","year":"2003","unstructured":"Gatza, M. L., Eatt, J. C & Marriott, S. J. Cellular transformation by the HTLV-I Tax protein, a jack-of-all-trades. Oncogene 22, 5141\u20135149 (2003).","journal-title":"Oncogene"},{"key":"BFncb1432_CR9","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/1742-4690-1-18","volume":"1","author":"Y-P Ching","year":"2004","unstructured":"Ching, Y.-P. et al. Specific TATAA and bZIP requirements suggest that HTLV-I Tax has transcriptional activity subsequent to the assembly of an initiation complex. Retrovirology 1, 18 (2004).","journal-title":"Retrovirology"},{"key":"BFncb1432_CR10","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/S0092-8674(00)81148-4","volume":"93","author":"D-Y Jin","year":"1998","unstructured":"Jin, D.-Y., Spencer, F. & Jeang, K.-T. Human T-cell leukemia virus type I oncoprotein Tax targets the human mitotic checkpoint protein MAD1. Cell 93, 81\u201391 (1998).","journal-title":"Cell"},{"key":"BFncb1432_CR11","doi-asserted-by":"publisher","first-page":"37736","DOI":"10.1074\/jbc.M301649200","volume":"278","author":"A Haoudi","year":"2003","unstructured":"Haoudi, A., Daniels, R. C., Wong, E., Kupfer, G. & Semmes, O. J. Human T-cell leukemia virus-I tax oncoprotein functionally targets a subnuclear complex involved in cellular DNA damage-response. J. Biol. Chem. 278, 37736\u201337744 (2003).","journal-title":"J. Biol. Chem."},{"key":"BFncb1432_CR12","doi-asserted-by":"publisher","first-page":"6241","DOI":"10.1038\/sj.onc.1205709","volume":"21","author":"S Duensing","year":"2002","unstructured":"Duensing, S. & Munger, K. Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability. Oncogene 21, 6241\u20136248 (2002).","journal-title":"Oncogene"},{"key":"BFncb1432_CR13","doi-asserted-by":"publisher","first-page":"5282","DOI":"10.1128\/MCB.23.15.5282-5292.2003","volume":"23","author":"M Forgues","year":"2003","unstructured":"Forgues, M. et al. Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles. Mol. Cell. Biol. 23, 5282\u20135292 (2003).","journal-title":"Mol. Cell. Biol."},{"key":"BFncb1432_CR14","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1083\/jcb.200506185","volume":"171","author":"C Zou","year":"2005","unstructured":"Zou, C. et al. Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication. J. Cell Biol. 171, 437\u2013445 (2005).","journal-title":"J. Cell Biol."},{"key":"BFncb1432_CR15","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1038\/10054","volume":"1","author":"P Meraldi","year":"1999","unstructured":"Meraldi, P., Lukas, J., Fry, A. M., Bartek, J. & Nigg, E. A. Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nature Cell Biol. 1, 88\u201393 (1999).","journal-title":"Nature Cell Biol."},{"key":"BFncb1432_CR16","doi-asserted-by":"publisher","first-page":"2817","DOI":"10.1073\/pnas.96.6.2817","volume":"96","author":"KR Lacey","year":"1999","unstructured":"Lacey, K. R., Jackson, P. K. & Stearns, T. Cyclin-dependent kinase control of centrosome duplication. Proc. Natl Acad. Sci. USA 96, 2817\u20132822 (1999).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFncb1432_CR17","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/S0960-9822(99)80191-2","volume":"9","author":"Y Matsumoto","year":"1999","unstructured":"Matsumoto, Y., Hayashi, K. & Nishida, E. Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells. Curr. Biol. 9, 429\u2013432 (1999).","journal-title":"Curr. Biol."},{"key":"BFncb1432_CR18","doi-asserted-by":"publisher","first-page":"18974","DOI":"10.1073\/pnas.0506659103","volume":"102","author":"JM Peloponese","year":"2005","unstructured":"Peloponese, J. M. Jr., Haller, K., Miyazato, A. & Jeang, K. T. Abnormal centrosome amplification in cells through the targeting of Ran-binding protein-1 by the human T cell leukemia virus type-1 Tax oncoprotein. Proc. Natl Acad. Sci. USA 102, 18974\u201318979 (2005).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFncb1432_CR19","doi-asserted-by":"publisher","first-page":"1689","DOI":"10.1089\/08892220050193155","volume":"16","author":"ACS Chun","year":"2000","unstructured":"Chun, A. C. S. et al. Coiled-coil motif as a structural basis for the interaction of HTLV-I Tax with cellular cofactors. AIDS Res. Hum. Retrov. 16, 1689\u20131694 (2000).","journal-title":"AIDS Res. Hum. Retrov."},{"key":"BFncb1432_CR20","doi-asserted-by":"publisher","first-page":"25816","DOI":"10.1074\/jbc.272.41.25816","volume":"272","author":"D-Y Jin","year":"1997","unstructured":"Jin, D.-Y. et al. A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor \u03b1. J. Biol. Chem. 272, 25816\u201325823 (1997).","journal-title":"J. Biol. Chem."},{"key":"BFncb1432_CR21","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.1083\/jcb.141.7.1563","volume":"141","author":"AM Fry","year":"1998","unstructured":"Fry, A. M. et al. C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2. J. Cell Biol. 141, 1563\u20131574 (1998).","journal-title":"J. Cell Biol."},{"key":"BFncb1432_CR22","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1083\/jcb.200207153","volume":"159","author":"J Yang","year":"2002","unstructured":"Yang, J. et al. Rootletin, a novel coiled-coil protein, is a structural component of the ciliary rootlet. J. Cell Biol. 159, 431\u2013440 (2002).","journal-title":"J. Cell Biol."},{"key":"BFncb1432_CR23","doi-asserted-by":"publisher","first-page":"4129","DOI":"10.1128\/MCB.25.10.4129-4137.2005","volume":"25","author":"J Yang","year":"2005","unstructured":"Yang, J. et al. The ciliary rootlet maintains long-term stability of sensory cilia. Mol. Cell. Biol. 25, 4129\u20134137 (2005).","journal-title":"Mol. Cell. Biol."},{"key":"BFncb1432_CR24","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1006\/viro.1996.0126","volume":"217","author":"OJ Semmes","year":"1996","unstructured":"Semmes, O. J. et al. HTLV-I and HTLV-II Tax: differences in induction of micronuclei in cells and transcriptional activation of viral LTRs. Virology 217, 373\u2013379 (1996).","journal-title":"Virology"},{"key":"BFncb1432_CR25","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1083\/jcb.200301105","volume":"161","author":"A Gromley","year":"2003","unstructured":"Gromley, A. et al. A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phase. J. Cell Biol. 161, 535\u2013545 (2003).","journal-title":"J. Cell Biol."},{"key":"BFncb1432_CR26","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1242\/jcs.115.9.1825","volume":"115","author":"YY Ou","year":"2002","unstructured":"Ou, Y. Y., Mack, G. J., Zhang, M. & Rattner, J. B. CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation. J. Cell Sci. 115, 1825\u20131835 (2002).","journal-title":"J. Cell Sci."},{"key":"BFncb1432_CR27","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/S0092-8674(00)00093-3","volume":"103","author":"M Okuda","year":"2000","unstructured":"Okuda, M. et al. Nucleophosmin\/B23 is a target of CDK2\/cyclin E in centrosome duplication. Cell 103, 127\u2013140 (2000).","journal-title":"Cell"},{"key":"BFncb1432_CR28","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1083\/jcb.200504107","volume":"171","author":"S Bahe","year":"2005","unstructured":"Bahe, S., Stierhof, Y.-D., Wilkinson, C. J., Leiss, F. & Nigg, E. A. Rootletin forms centriole-associated filaments and functions in centrosome cohesion. J. Cell Biol. 171, 27\u201333 (2005).","journal-title":"J. Cell Biol."},{"key":"BFncb1432_CR29","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1038\/ncb993","volume":"5","author":"C Wong","year":"2003","unstructured":"Wong, C. & Stearns, T. Centrosome number is controlled by a centrosome-intrinsic block to reduplication. Nature Cell Biol. 5, 539\u2013544 (2003).","journal-title":"Nature Cell Biol."},{"key":"BFncb1432_CR30","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1038\/nrc924","volume":"2","author":"EA Nigg","year":"2002","unstructured":"Nigg, E. A. Centrosome aberrations: cause or consequence of cancer progression? Nature Rev. Cancer. 2, 815\u2013825 (2002).","journal-title":"Nature Rev. Cancer."},{"key":"BFncb1432_CR31","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1083\/jcb.146.3.585","volume":"146","author":"A Khodjakov","year":"1999","unstructured":"Khodjakov, A. & Rieder, C. L. The sudden recruitment of \u03b3-tubulin to the centrosome at the onset of mitosis and its dynamic exchange throughout the cell cycle, do not require microtubules. J. Cell Biol. 146, 585\u2013596 (1999).","journal-title":"J. Cell Biol."},{"key":"BFncb1432_CR32","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.1093\/nar\/gki332","volume":"33","author":"K-T Chin","year":"2005","unstructured":"Chin, K.-T. et al. The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinoma. Nucl. Acids Res. 33, 1859\u20131873 (2005).","journal-title":"Nucl. Acids Res."},{"key":"BFncb1432_CR33","doi-asserted-by":"publisher","first-page":"15237","DOI":"10.1074\/jbc.C200032200","volume":"277","author":"YP Ching","year":"2003","unstructured":"Ching, Y. P., Pang, A. S., Lam, W. H., Qi, R. Z. & Wang, J. H. Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor. J. Biol. Chem. 277, 15237\u201315240 (2003).","journal-title":"J. Biol. Chem."},{"key":"BFncb1432_CR34","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1073\/pnas.032652399","volume":"99","author":"PJ Paddison","year":"2002","unstructured":"Paddison, P. J., Caudy, A. A. & Hannon, G. J. Stable suppression of gene expression by RNAi in mammalian cells. Proc. Natl Acad. Sci. USA 99, 1443\u20131448 (2002).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFncb1432_CR35","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1093\/emboj\/19.4.729","volume":"19","author":"DY Jin","year":"2000","unstructured":"Jin, D. Y. et al. Hepatitis C virus core protein-induced loss of LZIP function correlates with cellular transformation. EMBO J. 19, 729\u2013740 (2000).","journal-title":"EMBO J."},{"key":"BFncb1432_CR36","doi-asserted-by":"publisher","first-page":"10824","DOI":"10.1074\/jbc.M208310200","volume":"278","author":"YP Ching","year":"2003","unstructured":"Ching, Y. P. et al. Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma. J. Biol. Chem. 278, 10824\u201310830 (2003).","journal-title":"J. Biol. Chem."}],"container-title":["Nature Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ncb1432.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncb1432","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncb1432.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T19:28:25Z","timestamp":1684438105000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ncb1432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6,11]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2006,7]]}},"alternative-id":["BFncb1432"],"URL":"https:\/\/doi.org\/10.1038\/ncb1432","relation":{},"ISSN":["1465-7392","1476-4679"],"issn-type":[{"value":"1465-7392","type":"print"},{"value":"1476-4679","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6,11]]}}}