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A minimal way of capturing competitive abilities in a frequency-dependent manner is with an invasibility network specifying whether a species at low abundance can increase in frequency in an environment dominated by another species. Here, using a panel of prolific small-molecule producers and a habitat with feast-and-famine cycles, we show that the most abundant strain can often exclude other strains\u2014resulting in bistability between pairs of strains. Instead of a single winner, the empirically determined invasibility network is ruled by multiple strains that cannot invade each other, and does not contain loops of cyclic dominance. Antibiotic inhibition contributes to bistability by helping producers resist invasions while at high abundance and by reducing producers\u2019 ability to invade when at low abundance.<\/jats:p>","DOI":"10.1038\/ncomms11274","type":"journal-article","created":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T10:23:53Z","timestamp":1461234233000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":109,"title":["Inhibitory interactions promote frequent bistability among competing bacteria"],"prefix":"10.1038","volume":"7","author":[{"given":"Erik S.","family":"Wright","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalin H.","family":"Vetsigian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,4,21]]},"reference":[{"key":"BFncomms11274_CR1","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1038\/nrmicro1341","volume":"4","author":"JBH Martiny","year":"2006","unstructured":"Martiny, J. 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