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With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of\n                    <jats:italic>Biomphalaria glabrata,<\/jats:italic>\n                    a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of\n                    <jats:italic>B<\/jats:italic>\n                    .\n                    <jats:italic>glabrata<\/jats:italic>\n                    in the field and may define this species as a suitable snail host for\n                    <jats:italic>S<\/jats:italic>\n                    .\n                    <jats:italic>mansoni<\/jats:italic>\n                    . We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.\n                  <\/jats:p>","DOI":"10.1038\/ncomms15451","type":"journal-article","created":{"date-parts":[[2017,5,16]],"date-time":"2017-05-16T05:46:40Z","timestamp":1494913600000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":229,"title":["Whole genome analysis of a schistosomiasis-transmitting freshwater snail"],"prefix":"10.1038","volume":"8","author":[{"given":"Coen M.","family":"Adema","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LaDeana W.","family":"Hillier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine S.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric 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