{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:05:58Z","timestamp":1792008358885,"version":"4.4.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T00:00:00Z","timestamp":1330387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"},{"start":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T00:00:00Z","timestamp":1330387200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Commun"],"DOI":"10.1038\/ncomms1701","type":"journal-article","created":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T10:17:18Z","timestamp":1330424238000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":401,"title":["New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing"],"prefix":"10.1038","volume":"3","author":[{"given":"Andreas","family":"Keller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Graefen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Ball","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Matzas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valesca","family":"Boisguerin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Maixner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Leidinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Backes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabab","family":"Khairat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Forster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Stade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Franke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Mayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Spangler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"McLaughlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minita","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarence","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy T.","family":"Harkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Sartori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres","family":"Moreno-Estrada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenna","family":"Henn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Sikora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ornella","family":"Semino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Chiaroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siiri","family":"Rootsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie M.","family":"Myres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente M.","family":"Cabrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Underhill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos D.","family":"Bustamante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard Egarter","family":"Vigl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Samadelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Cipollini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Haas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Katus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian D.","family":"O'Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc R.J.","family":"Carlson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Meder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaus","family":"Blin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eckart","family":"Meese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten M.","family":"Pusch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Zink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,2,28]]},"reference":[{"key":"BFncomms1701_CR1","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1148\/radiol.2263020338","volume":"226","author":"WA Murphy Jr","year":"2003","unstructured":"Murphy, W. A. Jr et al. The Iceman: discovery and imaging. Radiology 226, 614\u2013629 (2003).","journal-title":"Radiology"},{"key":"BFncomms1701_CR2","doi-asserted-by":"publisher","first-page":"1775","DOI":"10.1126\/science.8209259","volume":"264","author":"O Handt","year":"1994","unstructured":"Handt, O. et al. Molecular genetic analyses of the Tyrolean Ice Man. Science 264, 1775\u20131778 (1994).","journal-title":"Science"},{"key":"BFncomms1701_CR3","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.1016\/j.cub.2008.09.028","volume":"18","author":"L Ermini","year":"2008","unstructured":"Ermini, L. et al. Complete mitochondrial genome sequence of the Tyrolean Iceman. Curr. Biol. 18, 1687\u20131693 (2008).","journal-title":"Curr. Biol."},{"key":"BFncomms1701_CR4","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1002\/ajpa.20384","volume":"130","author":"F Rollo","year":"2006","unstructured":"Rollo, F. et al. Fine characterization of the Iceman's mtDNA haplogroup. Am. J. Phys. Anthropol. 130, 557\u2013564 (2006).","journal-title":"Am. J. Phys. Anthropol."},{"key":"BFncomms1701_CR5","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1038\/nature08835","volume":"463","author":"M Rasmussen","year":"2010","unstructured":"Rasmussen, M. et al. Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature 463, 757\u2013762 (2010).","journal-title":"Nature"},{"key":"BFncomms1701_CR6","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1038\/nature08802","volume":"464","author":"Y He","year":"2010","unstructured":"He, Y. et al. Heteroplasmic mitochondrial DNA mutations in normal and tumour cells. Nature 464, 610\u2013614 (2010).","journal-title":"Nature"},{"key":"BFncomms1701_CR7","doi-asserted-by":"publisher","first-page":"14616","DOI":"10.1073\/pnas.0704665104","volume":"104","author":"AW Briggs","year":"2007","unstructured":"Briggs, A. W. et al. Patterns of damage in genomic DNA sequences from a Neandertal. Proc. Natl Acad. Sci. USA 104, 14616\u201314621 (2007).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFncomms1701_CR8","doi-asserted-by":"publisher","first-page":"2153","DOI":"10.1093\/bioinformatics\/btr347","volume":"27","author":"A Ginolhac","year":"2011","unstructured":"Ginolhac, A., Rasmussen, M., Gilbert, M. T., Willerslev, E. & Orlando, L. mapDamage: testing for damage patterns in ancient DNA sequences. Bioinformatics 27, 2153\u20132155 (2011).","journal-title":"Bioinformatics"},{"key":"BFncomms1701_CR9","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1126\/science.1211177","volume":"334","author":"M Rasmussen","year":"2011","unstructured":"Rasmussen, M. et al. An Aboriginal Australian genome reveals separate human dispersals into Asia. Science 334, 94\u201398 (2011).","journal-title":"Science"},{"key":"BFncomms1701_CR10","doi-asserted-by":"publisher","first-page":"e168","DOI":"10.1371\/journal.pgen.0020168","volume":"2","author":"KS Pollard","year":"2006","unstructured":"Pollard, K. S. et al. Forces shaping the fastest evolving regions in the human genome. PLoS Genet. 2, e168 (2006).","journal-title":"PLoS Genet."},{"key":"BFncomms1701_CR11","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.ajhg.2008.08.005","volume":"83","author":"MR Nelson","year":"2008","unstructured":"Nelson, M. R. et al. The population reference sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am. J. Hum. Genet. 83, 347\u2013358 (2008).","journal-title":"Am. J. Hum. Genet."},{"key":"BFncomms1701_CR12","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1038\/ng.139","volume":"40","author":"J Novembre","year":"2008","unstructured":"Novembre, J. & Stephens, M. Interpreting principal component analyses of spatial population genetic variation. Nat. Genet. 40, 646\u2013649 (2008).","journal-title":"Nat. Genet."},{"key":"BFncomms1701_CR13","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.ajhg.2010.05.018","volume":"87","author":"H Hunter-Zinck","year":"2010","unstructured":"Hunter-Zinck, H. et al. Population genetic structure of the people of Qatar. Am. J. Hum. Genet. 87, 17\u201325 (2010).","journal-title":"Am. J. Hum. Genet."},{"key":"BFncomms1701_CR14","unstructured":"Y-DNA Haplogroup Tree 2011 &lt;http:\/\/www.isogg.org\/tree\/&gt; (2011)."},{"key":"BFncomms1701_CR15","doi-asserted-by":"publisher","first-page":"e5792","DOI":"10.1371\/journal.pone.0005792","volume":"4","author":"LM Sims","year":"2009","unstructured":"Sims, L. M., Garvey, D. & Ballantyne, J. Improved resolution haplogroup G phylogeny in the Y chromosome, revealed by a set of newly characterized SNPs. PLoS One 4, e5792 (2009).","journal-title":"PLoS One"},{"key":"BFncomms1701_CR16","doi-asserted-by":"publisher","first-page":"2905","DOI":"10.1093\/molbev\/msr126","volume":"28","author":"O Balanovsky","year":"2011","unstructured":"Balanovsky, O. et al. Parallel evolution of genes and languages in the Caucasus region. Mol. Biol. Evol. 28, 2905\u20132920 (2011).","journal-title":"Mol. Biol. Evol."},{"key":"BFncomms1701_CR17","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.ympev.2006.11.030","volume":"44","author":"C Capelli","year":"2007","unstructured":"Capelli, C. et al. Y chromosome genetic variation in the Italian peninsula is clinal and supports an admixture model for the Mesolithic-Neolithic encounter. Mol. Phylogenet. Evol. 44, 228\u2013239 (2007).","journal-title":"Mol. Phylogenet. Evol."},{"key":"BFncomms1701_CR18","doi-asserted-by":"publisher","first-page":"9788","DOI":"10.1073\/pnas.1100723108","volume":"108","author":"M Lacan","year":"2011","unstructured":"Lacan, M. et al. Ancient DNA reveals male diffusion through the Neolithic Mediterranean route. Proc. Natl Acad. Sci. USA 108, 9788\u20139791 (2011).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFncomms1701_CR19","doi-asserted-by":"publisher","first-page":"e1000536","DOI":"10.1371\/journal.pbio.1000536","volume":"8","author":"W Haak","year":"2010","unstructured":"Haak, W. et al. Ancient DNA from European early neolithic farmers reveals their near eastern affinities. PLoS Biol. 8, e1000536 (2010).","journal-title":"PLoS Biol."},{"key":"BFncomms1701_CR20","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1038\/ng826","volume":"30","author":"NS Enattah","year":"2002","unstructured":"Enattah, N. S. et al. Identification of a variant associated with adult-type hypolactasia. Nat. Genet. 30, 233\u2013237 (2002).","journal-title":"Nat. Genet."},{"key":"BFncomms1701_CR21","doi-asserted-by":"publisher","first-page":"3736","DOI":"10.1073\/pnas.0607187104","volume":"104","author":"J Burger","year":"2007","unstructured":"Burger, J., Kirchner, M., Bramanti, B., Haak, W. & Thomas, M. G. Absence of the lactase-persistence-associated allele in early Neolithic Europeans. Proc. Natl Acad. Sci. USA 104, 3736\u20133741 (2007).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFncomms1701_CR22","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.eclnm.2009.10.004","volume":"5","author":"DA Obinu","year":"2010","unstructured":"Obinu, D. A. et al. Prevalence of lactase persistence and the performance of a non-invasive genetic test in adult Sardinian patients. Eur. e-J. Clin. Nutr. Metab. 5, e1\u2013e5 (2010).","journal-title":"Eur. e-J. Clin. Nutr. Metab."},{"key":"BFncomms1701_CR23","doi-asserted-by":"publisher","first-page":"1488","DOI":"10.1126\/science.1142447","volume":"316","author":"R McPherson","year":"2007","unstructured":"McPherson, R. et al. A common allele on chromosome 9 associated with coronary heart disease. Science 316, 1488\u20131491 (2007).","journal-title":"Science"},{"key":"BFncomms1701_CR24","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1159\/000236914","volume":"28","author":"MM Luke","year":"2009","unstructured":"Luke, M. M. et al. Polymorphisms associated with both noncardioembolic stroke and coronary heart disease: vienna stroke registry. Cerebrovasc. Dis. 28, 499\u2013504 (2009).","journal-title":"Cerebrovasc. Dis."},{"key":"BFncomms1701_CR25","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1161\/CIRCGENETICS.108.835173","volume":"2","author":"JG Smith","year":"2009","unstructured":"Smith, J. G. et al. Common genetic variants on chromosome 9p21 confers risk of ischemic stroke: a large-scale genetic association study. Circ. Cardiovasc. Genet. 2, 159\u2013164 (2009).","journal-title":"Circ. Cardiovasc. Genet."},{"key":"BFncomms1701_CR26","doi-asserted-by":"publisher","first-page":"2062","DOI":"10.1161\/CIRCULATIONAHA.109.879049","volume":"120","author":"C Newton-Cheh","year":"2009","unstructured":"Newton-Cheh, C. et al. A common variant at 9p21 is associated with sudden and arrhythmic cardiac death. Circulation 120, 2062\u20132068 (2009).","journal-title":"Circulation"},{"key":"BFncomms1701_CR27","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1161\/ATVBAHA.107.157248","volume":"28","author":"GQ Shen","year":"2008","unstructured":"Shen, G. Q. et al. Four SNPs on chromosome 9p21 in a South Korean population implicate a genetic locus that confers high cross-race risk for development of coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 28, 360\u2013365 (2008).","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"BFncomms1701_CR28","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/1471-2261-9-3","volume":"9","author":"SN Chen","year":"2009","unstructured":"Chen, S. N., Ballantyne, C. M., Gotto, A. M. Jr. & Marian, A. J. The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis. BMC Cardiovasc. Disord. 9, 3 (2009).","journal-title":"BMC Cardiovasc. Disord."},{"key":"BFncomms1701_CR29","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1038\/sj.jhh.1002234","volume":"21","author":"H Yasuda","year":"2007","unstructured":"Yasuda, H. et al. Association of single nucleotide polymorphisms in endothelin family genes with the progression of atherosclerosis in patients with essential hypertension. J. Hum. Hypertens. 21, 883\u2013892 (2007).","journal-title":"J. Hum. Hypertens."},{"key":"BFncomms1701_CR30","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.ajhg.2007.11.005","volume":"82","author":"RA Sturm","year":"2008","unstructured":"Sturm, R. A. et al. A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color. Am. J. Hum. Genet. 82, 424\u2013431 (2008).","journal-title":"Am. J. Hum. Genet."},{"key":"BFncomms1701_CR31","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1111\/j.1469-1809.2009.00504.x","volume":"73","author":"W Branicki","year":"2009","unstructured":"Branicki, W., Brudnik, U. & Wojas-Pelc, A. Interactions between HERC2, OCA2 and MC1R may influence human pigmentation phenotype. Ann. Hum. Genet. 73, 160\u2013170 (2009).","journal-title":"Ann. Hum. Genet."},{"key":"BFncomms1701_CR32","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1038\/345229a0","volume":"345","author":"F Yamamoto","year":"1990","unstructured":"Yamamoto, F., Clausen, H., White, T., Marken, J. & Hakomori, S. Molecular genetic basis of the histo-blood group ABO system. Nature 345, 229\u2013233 (1990).","journal-title":"Nature"},{"key":"BFncomms1701_CR33","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1016\/j.legalmed.2004.12.002","volume":"7","author":"S Iwamoto","year":"2005","unstructured":"Iwamoto, S. Molecular aspects of Rh antigens. Leg. Med. (Tokyo) 7, 270\u2013273 (2005).","journal-title":"Leg. Med. (Tokyo)"},{"key":"BFncomms1701_CR34","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1128\/CDLI.8.5.997-1002.2001","volume":"8","author":"C Stollberger","year":"2001","unstructured":"Stollberger, C., Molzer, G. & Finsterer, J. Seroprevalence of antibodies to microorganisms known to cause arterial and myocardial damage in patients with or without coronary stenosis. Clin. Diagn. Lab. Immunol. 8, 997\u20131002 (2001).","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"BFncomms1701_CR35","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.atherosclerosis.2004.10.048","volume":"184","author":"H Volzke","year":"2006","unstructured":"Volzke, H. et al. Seropositivity for anti-Borrelia IgG antibody is independently associated with carotid atherosclerosis. Atherosclerosis 184, 108\u2013112 (2006).","journal-title":"Atherosclerosis"},{"key":"BFncomms1701_CR36","doi-asserted-by":"crossref","unstructured":"Ammerman, A. J. & Cavalli-Sforza, L. L. The Neolithic Transition and the Genetics of Populations in Europe (Princeton University Press, 1984).","DOI":"10.1515\/9781400853113"},{"key":"BFncomms1701_CR37","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1126\/science.1089837","volume":"302","author":"W M\u00fcller","year":"2003","unstructured":"M\u00fcller, W., Fricke, H., Halliday, A. N., McCulloch, M. T. & Wartho, J. A. Origin and migration of the Alpine Iceman. Science 302, 862\u2013866 (2003).","journal-title":"Science"},{"key":"BFncomms1701_CR38","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/S1366-2120(08)70035-7","volume":"2","author":"M Scholz","year":"1997","unstructured":"Scholz, M. & Pusch, C. An efficient isolation method for high-quality DNA from ancient bones. Technical Tips Online 2, 61\u201364 (1997).","journal-title":"Technical Tips Online"},{"key":"BFncomms1701_CR39","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1001\/jama.2010.121","volume":"303","author":"Z Hawass","year":"2010","unstructured":"Hawass, Z. et al. Ancestry and pathology in King Tutankhamun's family. JAMA 303, 638\u2013647 (2010).","journal-title":"JAMA"},{"key":"BFncomms1701_CR40","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1006\/abio.2000.4666","volume":"284","author":"CM Pusch","year":"2000","unstructured":"Pusch, C. M., Bachmann, L., Broghammer, M. & Scholz, M. Internal Alu-polymerase chain reaction: a sensitive contamination monitoring protocol for DNA extracted from prehistoric animal bones. Anal. Biochem. 284, 408\u2013411 (2000).","journal-title":"Anal. Biochem."},{"key":"BFncomms1701_CR41","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/gm13","volume":"1","author":"PD Stenson","year":"2009","unstructured":"Stenson, P. D. et al. The Human Gene Mutation Database: 2008 update. Genome Med. 1, 13 (2009).","journal-title":"Genome Med."},{"key":"BFncomms1701_CR42","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1101\/gr.7172008","volume":"18","author":"TM Karafet","year":"2008","unstructured":"Karafet, T. M. et al. New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree. Genome Res. 18, 830\u2013838 (2008).","journal-title":"Genome Res."},{"key":"BFncomms1701_CR43","doi-asserted-by":"publisher","first-page":"e1002397","DOI":"10.1371\/journal.pgen.1002397","volume":"8","author":"BM Henn","year":"2012","unstructured":"Henn, B. M. et al. Genomic ancestry of North Africans supports back-to-Africa migrations. PLoS Genet. 8, e1002397 (2012).","journal-title":"PLoS Genet."},{"key":"BFncomms1701_CR44","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1101\/gr.5969107","volume":"17","author":"DH Huson","year":"2007","unstructured":"Huson, D. H., Auch, A. F., Qi, J. & Schuster, S. C. MEGAN analysis of metagenomic data. Genome Res. 17, 377\u2013386 (2007).","journal-title":"Genome Res."},{"key":"BFncomms1701_CR45","first-page":"81","volume":"14","author":"A Graefen","year":"2009","unstructured":"Graefen, A., Unterl\u00e4nder, M., Parzinger, H. & Burger, J. Multiplex-PCR as a tool for assessing ancient DNA preservation levels in human remains prior to next-generation sequencing. Bulletin de la Soci\u00e9t\u00e9 Suisse d'Anthropologie 14, 81 (2009).","journal-title":"Bulletin de la Soci\u00e9t\u00e9 Suisse d'Anthropologie"},{"key":"BFncomms1701_CR46","first-page":"368","volume":"59","author":"O Handt","year":"1996","unstructured":"Handt, O., Krings, M., Ward, R. H. & P\u00e4\u00e4bo, S. The retrieval of ancient human DNA sequences. Am. J. Hum. Genet. 59, 368\u2013376 (1996).","journal-title":"Am. J. Hum. Genet."},{"key":"BFncomms1701_CR47","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1126\/science.1118725","volume":"310","author":"W Haak","year":"2005","unstructured":"Haak, W. et al. Ancient DNA from the first European farmers in 7,500-year-old Neolithic sites. Science 310, 1016\u20131018 (2005).","journal-title":"Science"}],"container-title":["Nature Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/ncomms1701","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ncomms1701.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/ncomms1701.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T00:42:55Z","timestamp":1672965775000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ncomms1701"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,28]]},"references-count":47,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,1]]}},"alternative-id":["BFncomms1701"],"URL":"https:\/\/doi.org\/10.1038\/ncomms1701","relation":{},"ISSN":["2041-1723"],"issn-type":[{"value":"2041-1723","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,28]]},"assertion":[{"value":"28 October 2011","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 January 2012","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2012","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"J.S., S.M., M.S., C.L., T.T.H. and A.S. are employees of Life Technologies. M.M., V.B. and A.K were previously employed by Febit biomed GmbH.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"698"}}