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Only strains that express the virulence factors cholera toxin (CT) and toxin-coregulated pilus (TCP) are capable of pandemic spread of cholera diarrhoea. Regardless, all\n                    <jats:italic>V. cholerae<\/jats:italic>\n                    strains sequenced to date harbour genes for the type VI secretion system (T6SS) that translocates effectors into neighbouring eukaryotic and prokaryotic cells. Here we report that the effectors encoded within these conserved gene clusters differ widely among\n                    <jats:italic>V. cholerae<\/jats:italic>\n                    strains, and that immunity proteins encoded immediately downstream from the effector genes protect their host from neighbouring bacteria producing corresponding effectors. As a consequence, strains with matching effector-immunity gene sets can coexist, while strains with different sets compete against each other. Thus, the\n                    <jats:italic>V. cholerae<\/jats:italic>\n                    T6SS contributes to the competitive behaviour of this species.\n                  <\/jats:p>","DOI":"10.1038\/ncomms4549","type":"journal-article","created":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T06:20:05Z","timestamp":1396333205000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":209,"title":["The Vibrio cholerae type VI secretion system employs diverse effector modules for intraspecific competition"],"prefix":"10.1038","volume":"5","author":[{"given":"Daniel","family":"Unterweger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah T.","family":"Miyata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Bachmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa M.","family":"Brooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Travis","family":"Mullins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Kostiuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Provenzano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Pukatzki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,4,1]]},"reference":[{"key":"BFncomms4549_CR1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1128\/aem.37.1.91-103.1979","volume":"37","author":"J Kaper","year":"1979","unstructured":"Kaper, J., Lockman, H., Colwell, R. 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