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Here, we show that hybrids between some\n                    <jats:italic>A. thaliana<\/jats:italic>\n                    accessions show increased resistance to the biotrophic bacterial pathogen\n                    <jats:italic>Pseudomonas syringae<\/jats:italic>\n                    pv.\n                    <jats:italic>tomato<\/jats:italic>\n                    (\n                    <jats:italic>Pst<\/jats:italic>\n                    ) DC3000. Comparisons of transcriptomes between these hybrids and their parents after inoculation reveal that several key salicylic acid (SA) biosynthesis genes are significantly upregulated in hybrids. Moreover, SA levels are higher in hybrids than in either parent. Increased resistance to\n                    <jats:italic>Pst<\/jats:italic>\n                    DC3000 is significantly compromised in hybrids of\n                    <jats:italic>pad4<\/jats:italic>\n                    mutants in which the SA biosynthesis pathway is blocked. Finally, increased histone H3 acetylation of key SA biosynthesis genes correlates with their upregulation in infected hybrids. Our data demonstrate that enhanced activation of SA biosynthesis in\n                    <jats:italic>A. thaliana<\/jats:italic>\n                    hybrids may contribute to their increased resistance to a biotrophic bacterial pathogen.\n                  <\/jats:p>","DOI":"10.1038\/ncomms8309","type":"journal-article","created":{"date-parts":[[2015,6,12]],"date-time":"2015-06-12T05:43:43Z","timestamp":1434087823000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":134,"title":["Salicylic acid biosynthesis is enhanced and contributes to increased biotrophic pathogen resistance in Arabidopsis hybrids"],"prefix":"10.1038","volume":"6","author":[{"given":"Li","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bosheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-yu","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jigang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinnian","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangming","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengcai","family":"An","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing Wang","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,6,12]]},"reference":[{"key":"BFncomms8309_CR1","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1038\/nrg3503","volume":"14","author":"ZJ Chen","year":"2013","unstructured":"Chen, Z. 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