{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T08:33:44Z","timestamp":1700037224558},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2008,5,27]],"date-time":"2008-05-27T00:00:00Z","timestamp":1211846400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Rev Endocrinol"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1038\/ncpendmet0845","type":"journal-article","created":{"date-parts":[[2008,5,27]],"date-time":"2008-05-27T15:42:12Z","timestamp":1211902932000},"page":"376-377","source":"Crossref","is-referenced-by-count":2,"title":["Is denosumab a safe and effective treatment for postmenopausal osteoporosis?"],"prefix":"10.1038","volume":"4","author":[{"given":"Kathryn E","family":"Ackerman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,5,27]]},"reference":[{"key":"BFncpendmet0845_CR1","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/S0092-8674(00)80209-3","volume":"89","author":"WS Simonet","year":"1997","unstructured":"Simonet WS  et al. (1997) Osteoprotegrin: a novel secreted protein involved in the regulation of bone density. Cell 89: 309\u2013319","journal-title":"Cell"},{"issue":"Suppl 1","key":"BFncpendmet0845_CR2","doi-asserted-by":"publisher","first-page":"S7","DOI":"10.1186\/ar2171","volume":"9","author":"EM Schwarz","year":"2007","unstructured":"Schwarz EM and Ritchlin CT (2007) Clinical development of anti-RANKL therapy. Arthritis Res Ther 9 (Suppl 1): S7","journal-title":"Arthritis Res Ther"},{"key":"BFncpendmet0845_CR3","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1056\/NEJMoa044459","volume":"354","author":"MR McClung","year":"2006","unstructured":"McClung MR  et al. (2006) Denosumab in postmenopausal women with low bone mineral density. N Engl J Med 354: 821\u2013831","journal-title":"N Engl J Med"},{"key":"BFncpendmet0845_CR4","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1038\/ncpendmet0328","volume":"2","author":"MJ Favus","year":"2006","unstructured":"Favus MJ (2006) Does denosumab improve low BMD in postmenopausal women? Nat Clin Pract Endocrinol Metab 2: 600\u2013601","journal-title":"Nat Clin Pract Endocrinol Metab"},{"key":"BFncpendmet0845_CR5","doi-asserted-by":"publisher","first-page":"2390","DOI":"10.1056\/NEJMc060819","volume":"354","author":"J Schwartzman","year":"2006","unstructured":"Schwartzman J and Yazici Y (2006) Denosumab in postmenopausal women with low bone mineral density. N Engl J Med 354: 2390\u20132391; author reply 2390\u20132391","journal-title":"N Engl J Med"}],"container-title":["Nature Clinical Practice Endocrinology & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ncpendmet0845.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncpendmet0845","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncpendmet0845.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T19:56:12Z","timestamp":1684439772000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ncpendmet0845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,27]]},"references-count":5,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["BFncpendmet0845"],"URL":"https:\/\/doi.org\/10.1038\/ncpendmet0845","relation":{},"ISSN":["1745-8366","1745-8374"],"issn-type":[{"value":"1745-8366","type":"print"},{"value":"1745-8374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,27]]}}}