{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:24:24Z","timestamp":1793139864472,"version":"4.5.0"},"reference-count":86,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2008,4,8]],"date-time":"2008-04-08T00:00:00Z","timestamp":1207612800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Rev Neurol"],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.1038\/ncpneuro0775","type":"journal-article","created":{"date-parts":[[2008,4,8]],"date-time":"2008-04-08T15:44:27Z","timestamp":1207669467000},"page":"254-266","source":"Crossref","is-referenced-by-count":128,"title":["Sleep disturbances in patients with parkinsonism"],"prefix":"10.1038","volume":"4","author":[{"given":"Val\u00e9rie Cochen","family":"De Cock","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Vidailhet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Arnulf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,4,8]]},"reference":[{"key":"BFncpneuro0775_CR1","unstructured":"American Academy of Sleep Medicine (2005) The International Classification of Sleep Disorders\u2014Revised. Chicago: American Academy of Sleep Medicine"},{"key":"BFncpneuro0775_CR2","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1002\/mds.870130606","volume":"13","author":"E Tandberg","year":"1998","unstructured":"Tandberg E  et al. (1998) A community-based study of sleep disorders in patients with Parkinson's disease. Mov Disord 13: 895\u2013899","journal-title":"Mov Disord"},{"key":"BFncpneuro0775_CR3","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1097\/00002826-198812000-00004","volume":"11","author":"AJ Lees","year":"1988","unstructured":"Lees AJ  et al. (1988) The night-time problems of Parkinson's disease. Clin Neuropharmacol 11: 512\u2013519","journal-title":"Clin Neuropharmacol"},{"key":"BFncpneuro0775_CR4","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1136\/jnnp.72.6.798","volume":"72","author":"I Ghorayeb","year":"2002","unstructured":"Ghorayeb I  et al. (2002) Sleep disorders and their determinants in multiple system atrophy. J Neurol Neurosurg Psychiatry 72: 798\u2013800","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"BFncpneuro0775_CR5","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1212\/WNL.49.4.999","volume":"49","author":"J Montplaisir","year":"1997","unstructured":"Montplaisir J  et al. (1997) Sleep and quantitative EEG in patients with progressive supranuclear palsy. Neurology 49: 999\u20131003","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR6","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1212\/WNL.58.3.465","volume":"58","author":"E Tan","year":"2002","unstructured":"Tan E  et al. (2002) Evaluation of somnolence in Parkinson's disease: comparison with age- and sex-matched controls. Neurology 58: 465\u2013468","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR7","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1002\/mds.870050404","volume":"5","author":"SA Factor","year":"1990","unstructured":"Factor SA  et al. (1990) Sleep disorders and sleep effect in Parkinson's disease. Mov Disord 5: 280\u2013285","journal-title":"Mov Disord"},{"key":"BFncpneuro0775_CR8","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1001\/archneur.1994.00540210094018","volume":"51","author":"B Van Hilten","year":"1994","unstructured":"Van Hilten B  et al. (1994) Sleep disruption in Parkinson's disease. Assessment by continuous activity monitoring. Arch Neurol 51: 922\u2013928","journal-title":"Arch Neurol"},{"key":"BFncpneuro0775_CR9","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/jnnp.73.6.629","volume":"73","author":"KR Chaudhuri","year":"2002","unstructured":"Chaudhuri KR  et al. (2002) The Parkinson's disease sleep scale: a new instrument for assessing sleep and nocturnal disability in Parkinson's disease. J Neurol Neurosurg Psychiatry 73: 629\u2013635","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"BFncpneuro0775_CR10","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.1212\/WNL.55.11.1732","volume":"55","author":"I Arnulf","year":"2000","unstructured":"Arnulf I  et al. (2000) Improvement of sleep architecture in PD with subthalamic nucleus stimulation. Neurology 55: 1732\u20131735","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR11","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1136\/jnnp.72.5.661","volume":"72","author":"A Iranzo","year":"2002","unstructured":"Iranzo A  et al. (2002) Sleep symptoms and polysomnographic architecture in advanced Parkinson's disease after chronic bilateral subthalamic stimulation. J Neurol Neurosurg Psychiatry 72: 661\u2013664","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"BFncpneuro0775_CR12","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1007\/s00415-004-0305-7","volume":"251","author":"C Monaca","year":"2004","unstructured":"Monaca C  et al. (2004) Effects of bilateral stimulation on sleep in Parkinson's disease. J Neurol 251: 214\u2013218","journal-title":"J Neurol"},{"key":"BFncpneuro0775_CR13","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1001\/archneur.59.3.421","volume":"59","author":"W Ondo","year":"2002","unstructured":"Ondo W  et al. (2002) Exploring the relationship between Parkinson disease and restless legs syndrome. Arch Neurol 59: 421\u2013424","journal-title":"Arch Neurol"},{"key":"BFncpneuro0775_CR14","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1002\/mds.20734","volume":"21","author":"T Nomura","year":"2006","unstructured":"Nomura T  et al. (2006) Prevalence and clinical characteristics of restless legs syndrome in Japanese patients with Parkinson's disease. Mov Dis 21: 380\u2013384","journal-title":"Mov Dis"},{"key":"BFncpneuro0775_CR15","doi-asserted-by":"publisher","first-page":"958","DOI":"10.4088\/JCP.v67n0613","volume":"67","author":"LL Borek","year":"2006","unstructured":"Borek LL  et al. (2006) Mood and sleep in Parkinson's disease. J Clin Psychiatry 67: 958\u2013963","journal-title":"J Clin Psychiatry"},{"key":"BFncpneuro0775_CR16","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1212\/01.WNL.0000158652.74601.48","volume":"64","author":"CL Comella","year":"2005","unstructured":"Comella CL  et al. (2005) Nocturnal activity with nighttime pergolide in Parkinson disease: a controlled study using actigraphy. Neurology 64: 1450\u20131451","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR17","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/j.sleep.2005.04.004","volume":"6","author":"GA Dowling","year":"2005","unstructured":"Dowling GA  et al. (2005) Melatonin for sleep disturbances in Parkinson's disease. Sleep Med 6: 459\u2013466","journal-title":"Sleep Med"},{"key":"BFncpneuro0775_CR18","first-page":"301","volume":"57","author":"K Abe","year":"2005","unstructured":"Abe K  et al. (2005) A hypnotic drug for sleep disturbances in patients with Parkinson's disease [Japanese]. No To Shinkei 57: 301\u2013305","journal-title":"No To Shinkei"},{"key":"BFncpneuro0775_CR19","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1002\/mds.870080209","volume":"8","author":"G Linazasoro","year":"1993","unstructured":"Linazasoro G  et al. (1993) Nocturnal akathisia in Parkinson's disease: treatment with clozapine. Mov Disord 8: 171\u2013174","journal-title":"Mov Disord"},{"key":"BFncpneuro0775_CR20","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1097\/01.wnf.0000174932.82134.e2","volume":"28","author":"C Juri","year":"2005","unstructured":"Juri C  et al. (2005) Quetiapine for insomnia in Parkinson disease: results from an open-label trial. Clin Neuropharmacol 28: 185\u2013187","journal-title":"Clin Neuropharmacol"},{"key":"BFncpneuro0775_CR21","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/S1474-4422(07)70108-4","volume":"6","author":"WH Poewe","year":"2007","unstructured":"Poewe WH  et al. (2007) Efficacy of pramipexole and transdermal rotigotine in advanced Parkinson's disease: a double-blind, double-dummy, randomised controlled trial. Lancet Neurol 6: 513\u2013520","journal-title":"Lancet Neurol"},{"key":"BFncpneuro0775_CR22","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1111\/j.1365-2125.1987.tb03223.x","volume":"24","author":"AL Leeman","year":"1987","unstructured":"Leeman AL  et al. (1987) Parkinson's disease in the elderly: response to and optimal spacing of night time dosing with levodopa. Br J Clin Pharmacol 24: 637\u2013643","journal-title":"Br J Clin Pharmacol"},{"key":"BFncpneuro0775_CR23","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1523\/JNEUROSCI.2244-05.2006","volume":"26","author":"J Lu","year":"2006","unstructured":"Lu J  et al. (2006) Identification of wake-active neurones in the ventral periaqueducal gray matter. J Neurosci 26: 193\u2013202","journal-title":"J Neurosci"},{"key":"BFncpneuro0775_CR24","doi-asserted-by":"publisher","first-page":"2410","DOI":"10.1212\/01.WNL.0000147288.26029.B8","volume":"63","author":"S Kedia","year":"2004","unstructured":"Kedia S  et al. (2004) Emergence of restless legs syndrome during subthalamic stimulation for Parkinson disease. Neurology 63: 2410\u20132412","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR25","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1002\/mds.1120","volume":"16","author":"B Boeve","year":"2001","unstructured":"Boeve B  et al. (2001) Association of REM sleep behavior disorder and neurodegenerative disease may reflect an underlying synucleinopathy. Mov Disord 16: 622\u2013630","journal-title":"Mov Disord"},{"key":"BFncpneuro0775_CR26","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1093\/sleep\/30.8.1026","volume":"30","author":"VC De Cock","year":"2007","unstructured":"De Cock VC  et al. (2007) REM sleep behavior disorder in patients with guadeloupean parkinsonism, a tauopathy. Sleep 30: 1026\u20131032","journal-title":"Sleep"},{"key":"BFncpneuro0775_CR27","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1212\/01.wnl.0000233926.47469.73","volume":"67","author":"JF Gagnon","year":"2006","unstructured":"Gagnon JF  et al. (2006) Update on the pharmacology of REM sleep behavior disorder. Neurology 67: 742\u2013747","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR28","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1212\/01.wnl.0000168864.97813.e0","volume":"65","author":"A Iranzo","year":"2005","unstructured":"Iranzo A  et al. (2005) Characteristics of idiopathic REM sleep behavior disorder and that associated with MSA and PD. Neurology 65: 247\u2013252","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR29","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1007\/s10072-004-0364-7","volume":"25","author":"C Scaglione","year":"2005","unstructured":"Scaglione C  et al. (2005) REM sleep behaviour disorder in Parkinson's disease: a questionnaire-based study. Neurol Sci 25: 316\u2013321","journal-title":"Neurol Sci"},{"key":"BFncpneuro0775_CR30","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1093\/brain\/awl363","volume":"130","author":"VC De Cock","year":"2007","unstructured":"De Cock VC  et al. (2007) Restoration of normal motor control in Parkinson's disease during REM sleep. Brain 130: 450\u2013456","journal-title":"Brain"},{"key":"BFncpneuro0775_CR31","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1093\/sleep\/25.2.120","volume":"25","author":"CH Schenck","year":"2002","unstructured":"Schenck CH and Mahowald MW (2002) REM sleep behavior disorder: clinical, developmental, and neuroscience perspectives 16 years after its formal identification in SLEEP. Sleep 25: 120\u2013138","journal-title":"Sleep"},{"key":"BFncpneuro0775_CR32","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1212\/01.wnl.0000179346.39655.e0","volume":"65","author":"ML Fantini","year":"2005","unstructured":"Fantini ML  et al. (2005) Aggressive dream content without daytime aggressiveness in REM sleep behavior disorder. Neurology 65: 1010\u20131015","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR33","doi-asserted-by":"publisher","first-page":"2770","DOI":"10.1093\/brain\/awm056","volume":"130","author":"BF Boeve","year":"2007","unstructured":"Boeve BF  et al. (2007) Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain 130: 2770\u20132788","journal-title":"Brain"},{"key":"BFncpneuro0775_CR34","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1016\/0031-9384(79)90344-5","volume":"22","author":"J Sastre","year":"1979","unstructured":"Sastre J and Jouvet M (1979) Oneiric behavior in cats [French]. Physiol Behav 22: 979\u2013989","journal-title":"Physiol Behav"},{"key":"BFncpneuro0775_CR35","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/0304-3940(89)90503-X","volume":"98","author":"E Schenkel","year":"1989","unstructured":"Schenkel E and Siegel J (1989) REM sleep without atonia after lesions of the medial medulla. Neurosci Lett 98: 159\u2013165","journal-title":"Neurosci Lett"},{"key":"BFncpneuro0775_CR36","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1046\/j.1460-9568.2003.02861.x","volume":"18","author":"R Boissard","year":"2003","unstructured":"Boissard R  et al. (2003) Localization of the GABAergic and non-GABAergic neurons projecting to the sublaterodorsal nucleus and potentially gating paradoxical sleep onset. Eur J Neurosci 18: 1627\u20131639","journal-title":"Eur J Neurosci"},{"key":"BFncpneuro0775_CR37","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1038\/nature04767","volume":"441","author":"J Lu","year":"2006","unstructured":"Lu J  et al. (2006) A putative flip\u2013flop switch for control of REM sleep. Nature 441: 589\u2013594","journal-title":"Nature"},{"key":"BFncpneuro0775_CR38","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1212\/WNL.55.2.281","volume":"55","author":"I Arnulf","year":"2000","unstructured":"Arnulf I  et al. (2000) Hallucinations, REM sleep and Parkinson's disease. Neurology 55: 281\u2013288","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR39","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1093\/jnen\/61.5.413","volume":"61","author":"K Del Tredici","year":"2002","unstructured":"Del Tredici K  et al. (2002) Where does Parkinson disease pathology begin in the brain? J Neuropathol Exp Neurol 61: 413\u2013426","journal-title":"J Neuropathol Exp Neurol"},{"key":"BFncpneuro0775_CR40","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1093\/sleep\/9.2.293","volume":"9","author":"CH Schenck","year":"1986","unstructured":"Schenck CH  et al. (1986) Chronic behavioral disorders of human REM sleep: a new category of parasomnia. Sleep 9: 293\u2013308","journal-title":"Sleep"},{"key":"BFncpneuro0775_CR41","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1002\/1531-8257(199905)14:3<507::AID-MDS1021>3.0.CO;2-8","volume":"14","author":"D Kunz","year":"1999","unstructured":"Kunz D and Bes F (1999) Melatonin as a therapy in REM sleep behavior disorder patients: an open-labeled pilot study on the possible influence of melatonin on REM-sleep regulation. Mov Disord 14: 507\u2013511","journal-title":"Mov Disord"},{"key":"BFncpneuro0775_CR42","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1093\/brain\/123.2.331","volume":"123","author":"EJ Olson","year":"2000","unstructured":"Olson EJ  et al. (2000) Rapid eye movement sleep behaviour disorder: demographic, clinical and laboratory findings in 93 cases. Brain 123: 331\u2013339","journal-title":"Brain"},{"issue":"Suppl","key":"BFncpneuro0775_CR43","first-page":"A316","volume":"26","author":"CH Schenck","year":"2003","unstructured":"Schenck CH  et al. (2003) REM behavior disorder: delayed emergence of parkinsonism and\/or dementia in 65 % of older men initially diagnosed with idiopathic RBD, and an analysis of the minimum and maximum tonic and\/or phasic electromyographic abnormalities found during REM sleep [abstract]. Sleep 26 (Suppl): A316","journal-title":"Sleep"},{"key":"BFncpneuro0775_CR44","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1212\/WNL.46.2.388","volume":"46","author":"CH Schenck","year":"1996","unstructured":"Schenck CH  et al. (1996) Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behaviour disorder. Neurology 46: 388\u2013393","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR45","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/S1474-4422(06)70476-8","volume":"5","author":"A Iranzo","year":"2006","unstructured":"Iranzo A  et al. (2006) Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative disorder: a descriptive study. Lancet Neurol 5: 572\u2013577","journal-title":"Lancet Neurol"},{"key":"BFncpneuro0775_CR46","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1093\/brain\/123.6.1155","volume":"123","author":"I Eisensehr","year":"2000","unstructured":"Eisensehr I  et al. (2000) Reduced striatal dopamine transporters in idiopathic rapid eye movement sleep behavior disorder. Comparison with Parkinson's disease and controls. Brain 123: 1155\u20131160","journal-title":"Brain"},{"key":"BFncpneuro0775_CR47","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1212\/01.WNL.0000101726.69701.FA","volume":"62","author":"L Ferini-Strambi","year":"2004","unstructured":"Ferini-Strambi L  et al. (2004) Neuropsychological assessment in idiopathic REM sleep behavior disorder (RBD): does the idiopathic form of RBD really exist? Neurology 62: 41\u201345","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR48","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1093\/sleep\/19.5.367","volume":"19","author":"L Ferini-Strambi","year":"1996","unstructured":"Ferini-Strambi L  et al. (1996) Cardiac autonomic activity during wakefulness and sleep in REM sleep behavior disorder. Sleep 19: 367\u2013369","journal-title":"Sleep"},{"key":"BFncpneuro0775_CR49","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1093\/brain\/awh322","volume":"128","author":"K Stiasny-Kolster","year":"2005","unstructured":"Stiasny-Kolster K  et al. (2005) Combination of 'idiopathic' REM sleep behaviour disorder and olfactory dysfunction as possible indicator for \u03b1-synucleinopathy demonstrated by dopamine transporter FP-CIT-SPECT. Brain 128: 126\u2013137","journal-title":"Brain"},{"key":"BFncpneuro0775_CR50","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1002\/ana.10547","volume":"53","author":"ML Fantini","year":"2003","unstructured":"Fantini ML  et al. (2003) Slowing of electroencephalogram in rapid eye movement sleep behavior disorder. Ann Neurol 53: 774\u2013780","journal-title":"Ann Neurol"},{"key":"BFncpneuro0775_CR51","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1002\/mds.20582","volume":"20","author":"C Pacchetti","year":"2005","unstructured":"Pacchetti C  et al. (2005) Relationship between hallucinations, delusions, and rapid eye movement sleep behavior disorder in Parkinson's disease. Mov Disord 20: 1439\u20131448","journal-title":"Mov Disord"},{"key":"BFncpneuro0775_CR52","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1212\/01.WNL.0000106460.34682.E9","volume":"62","author":"JF Gagnon","year":"2004","unstructured":"Gagnon JF  et al. (2004) Association between waking EEG slowing and REM sleep behavior disorder in PD without dementia. Neurology 62: 401\u2013406","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR53","doi-asserted-by":"publisher","first-page":"1843","DOI":"10.1212\/01.wnl.0000278114.14096.74","volume":"69","author":"M Vendette","year":"2007","unstructured":"Vendette M  et al. (2007) REM sleep behavior disorder predicts cognitive impairment in Parkinson disease without dementia. Neurology 69: 1843\u20131849","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR54","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","volume":"14","author":"MH Johns","year":"1991","unstructured":"Johns MH (1991) A new method for measuring daytime sleepiness: the Epworth Sleepiness Scale. Sleep 14: 540\u2013545","journal-title":"Sleep"},{"key":"BFncpneuro0775_CR55","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1001\/jama.287.4.455","volume":"287","author":"D Hobson","year":"2002","unstructured":"Hobson D  et al. (2002) Excessive daytime sleepiness and sudden-onset sleep in Parkinson disease. A survey by the Canadian Movement Disorder Group. JAMA 287: 455\u2013463","journal-title":"JAMA"},{"key":"BFncpneuro0775_CR56","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1212\/WNL.57.8.1392","volume":"57","author":"WG Ondo","year":"2001","unstructured":"Ondo WG  et al. (2001) Daytime sleepiness and other sleep disorders in Parkinson's disease. Neurology 57: 1392\u20131396","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR57","doi-asserted-by":"publisher","first-page":"1567","DOI":"10.1002\/mds.21541","volume":"22","author":"I Ghorayeb","year":"2007","unstructured":"Ghorayeb I  et al. (2007) A nationwide survey of excessive daytime sleepiness in Parkinson's disease in France. Mov Disord 22: 1567\u20131572","journal-title":"Mov Disord"},{"key":"BFncpneuro0775_CR58","doi-asserted-by":"publisher","first-page":"1544","DOI":"10.1212\/WNL.58.10.1544","volume":"58","author":"MD Gjerstad","year":"2002","unstructured":"Gjerstad MD  et al. (2002) Development of daytime somnolence over time in Parkinson's disease. Neurology 58: 1544\u20131546","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR59","doi-asserted-by":"publisher","first-page":"1442","DOI":"10.1212\/01.wnl.0000183056.89590.0d","volume":"65","author":"RD Abbott","year":"2005","unstructured":"Abbott RD  et al. (2005) Excessive daytime sleepiness and subsequent development of Parkinson disease. Neurology 65: 1442\u20131446","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR60","doi-asserted-by":"publisher","first-page":"1908","DOI":"10.1212\/WNL.52.9.1908","volume":"52","author":"S Frucht","year":"1999","unstructured":"Frucht S  et al. (1999) Falling asleep at the wheel: motor vehicle mishaps in persons taking pramipexole and ropinirole. Neurology 52: 1908\u20131910","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR61","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1002\/mds.20163","volume":"19","author":"Y Korner","year":"2004","unstructured":"Korner Y  et al. (2004) Predictors of sudden onset of sleep in Parkinson's disease. Mov Disord 19: 1298\u20131305","journal-title":"Mov Disord"},{"key":"BFncpneuro0775_CR62","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1212\/WNL.58.7.1019","volume":"58","author":"I Arnulf","year":"2002","unstructured":"Arnulf I  et al. (2002) Parkinson's disease and sleepiness: an integral part of PD. Neurology 58: 1019\u20131024","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR63","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.smrv.2005.01.001","volume":"9","author":"I Arnulf","year":"2005","unstructured":"Arnulf I (2005) Excessive daytime sleepiness and parkinsonism. Sleep Med Rev 9: 185\u2013200","journal-title":"Sleep Med Rev"},{"key":"BFncpneuro0775_CR64","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1093\/sleep\/28.4.418","volume":"28","author":"I Arnulf","year":"2005","unstructured":"Arnulf I  et al. (2005) REM sleep behavior disorder and REM sleep without atonia in patients with progressive supranuclear palsy. Sleep 28: 349\u2013354","journal-title":"Sleep"},{"key":"BFncpneuro0775_CR65","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1001\/archneur.61.1.97","volume":"61","author":"A Razmy","year":"2004","unstructured":"Razmy A  et al. (2004) Predictors of impaired daytime sleep and wakefulness in patients with Parkinson's disease treated with older (ergot) vs newer (nonergot) dopamine agonists. Arch Neurol 61: 97\u2013102","journal-title":"Arch Neurol"},{"key":"BFncpneuro0775_CR66","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1046\/j.1365-2869.2000.00201.x","volume":"9","author":"DB Rye","year":"2000","unstructured":"Rye DB  et al. (2000) FAST TRACK: daytime sleepiness in Parkinson's disease. J Sleep Res 9: 63\u201369","journal-title":"J Sleep Res"},{"key":"BFncpneuro0775_CR67","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/BF03159935","volume":"14","author":"KA Jellinger","year":"1991","unstructured":"Jellinger KA (1991) Pathology of Parkinson's disease: changes other than the nigrostriatal pathways. Mol Chem Neuropathol 14: 153\u2013197","journal-title":"Mol Chem Neuropathol"},{"key":"BFncpneuro0775_CR68","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.1093\/brain\/awm090","volume":"130","author":"R Fronczek","year":"2007","unstructured":"Fronczek R  et al. (2007) Hypocretin (orexin) loss in Parkinson's disease. Brain 130: 1577\u20131585","journal-title":"Brain"},{"key":"BFncpneuro0775_CR69","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1093\/brain\/awm097","volume":"130","author":"TC Thannickal","year":"2007","unstructured":"Thannickal TC  et al. (2007) Hypocretin (orexin) cell loss in Parkinson's disease. Brain 130: 1586\u20131595","journal-title":"Brain"},{"key":"BFncpneuro0775_CR70","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/S0140-6736(83)91613-6","volume":"1","author":"M Garbarg","year":"1983","unstructured":"Garbarg M  et al. (1983) Brain histidine decarboxylase activity in Parkinson's disease. Lancet 1: 74\u201375","journal-title":"Lancet"},{"key":"BFncpneuro0775_CR71","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1093\/brain\/122.8.1437","volume":"122","author":"P Damier","year":"1999","unstructured":"Damier P  et al. (1999) The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain 122: 1437\u20131448","journal-title":"Brain"},{"key":"BFncpneuro0775_CR72","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1007\/BF00181955","volume":"95","author":"JM Monti","year":"1988","unstructured":"Monti JM  et al. (1988) Biphasic effects of dopamine D-2 receptor agonists on sleep and wakefulness in the rat. Psychopharmacology (Berl) 95: 395\u2013400","journal-title":"Psychopharmacology (Berl)"},{"key":"BFncpneuro0775_CR73","doi-asserted-by":"publisher","first-page":"1636","DOI":"10.1136\/jnnp.2005.065870","volume":"76","author":"WG Ondo","year":"2005","unstructured":"Ondo WG  et al. (2005) Modafinil for daytime somnolence in Parkinson's disease: double blind, placebo controlled parallel trial. J Neurol Neurosurg Psychiatry 76: 1636\u20131639","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"BFncpneuro0775_CR74","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1007\/s002210000370","volume":"133","author":"P Jenner","year":"2000","unstructured":"Jenner P  et al. (2000) Antiparkinsonian and neuroprotective effects of modafinil in the mptp-treated common marmoset. Exp Brain Res 133: 178\u2013188","journal-title":"Exp Brain Res"},{"key":"BFncpneuro0775_CR75","doi-asserted-by":"publisher","first-page":"2474","DOI":"10.1111\/j.1460-9568.2004.03694.x","volume":"20","author":"C Monaca","year":"2004","unstructured":"Monaca C  et al. (2004) Vigilance states in a parkinsonian model, the MPTP mouse. Eur J Neurosci 20: 2474\u20132478","journal-title":"Eur J Neurosci"},{"key":"BFncpneuro0775_CR76","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.sleep.2003.07.002","volume":"5","author":"R Vetrugno","year":"2004","unstructured":"Vetrugno R  et al. (2004) Sleep disorders in multiple system atrophy: a correlative video-polysomnographic study. Sleep Med 5: 21\u201330","journal-title":"Sleep Med"},{"key":"BFncpneuro0775_CR77","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1016\/S0140-6736(00)02824-5","volume":"356","author":"A Iranzo","year":"2000","unstructured":"Iranzo A  et al. (2000) Continuous positive air pressure eliminates nocturnal stridor in multiple system atrophy. Barcelona Multiple System Atrophy Study Group. Lancet 356: 1329\u20131330","journal-title":"Lancet"},{"key":"BFncpneuro0775_CR78","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1212\/01.WNL.0000137043.76383.A4","volume":"63","author":"A Iranzo","year":"2004","unstructured":"Iranzo A  et al. (2004) Long-term effect of CPAP in the treatment of nocturnal stridor in multiple system atrophy. Neurology 63: 930\u2013932","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR79","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1212\/WNL.59.4.585","volume":"59","author":"JF Gagnon","year":"2002","unstructured":"Gagnon JF  et al. (2002) REM sleep behavior disorder and REM sleep without atonia in Parkinson's disease. Neurology 59: 585\u2013589","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR80","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1212\/WNL.48.4.1094","volume":"48","author":"G Plazzi","year":"1997","unstructured":"Plazzi G  et al. (1997) REM sleep behavior disorders in multiple system atrophy. Neurology 48: 1094\u20131097","journal-title":"Neurology"},{"key":"BFncpneuro0775_CR81","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1093\/sleep\/29.10.1321","volume":"29","author":"JF Gagnon","year":"2006","unstructured":"Gagnon JF  et al. (2006) REM sleep behavior disorder and REM sleep without atonia in probable Alzheimer disease. Sleep 29: 1321\u20131325","journal-title":"Sleep"},{"key":"BFncpneuro0775_CR82","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1001\/archneur.63.2.268","volume":"63","author":"BF Boeve","year":"2006","unstructured":"Boeve BF  et al. (2006) Absence of rapid eye movement sleep behavior disorder in 11 members of the pallidopontonigral degeneration kindred. Arch Neurol 63: 268\u2013272","journal-title":"Arch Neurol"},{"key":"BFncpneuro0775_CR83","unstructured":"Arnulf I  et al.: REM sleep disturbances in Huntington disease. Arch Neurol, in press"},{"key":"BFncpneuro0775_CR84","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1002\/mds.10509","volume":"18","author":"A Iranzo","year":"2003","unstructured":"Iranzo A  et al. (2003) REM sleep behavior disorder and vocal cord paralysis in Machado\u2013Joseph disease. Mov Disord 18: 1179\u20131183","journal-title":"Mov Disord"},{"key":"BFncpneuro0775_CR85","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1002\/ana.20272","volume":"56","author":"H Kumru","year":"2004","unstructured":"Kumru H  et al. (2004) Rapid eye movement sleep behavior disorder in parkinsonism with parkin mutations. Ann Neurol 56: 599\u2013603","journal-title":"Ann Neurol"},{"key":"BFncpneuro0775_CR86","first-page":"55","volume":"86","author":"K Jellinger","year":"2001","unstructured":"Jellinger K (2001) The pathology of Parkinson's disease. Adv Neurol 86: 55\u201372","journal-title":"Adv Neurol"}],"container-title":["Nature Clinical Practice Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ncpneuro0775.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncpneuro0775","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncpneuro0775.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T20:32:47Z","timestamp":1684441967000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ncpneuro0775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4,8]]},"references-count":86,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["BFncpneuro0775"],"URL":"https:\/\/doi.org\/10.1038\/ncpneuro0775","relation":{},"ISSN":["1745-834X","1745-8358"],"issn-type":[{"value":"1745-834X","type":"print"},{"value":"1745-8358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,8]]}}}