{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:21:37Z","timestamp":1777695697863,"version":"3.51.4"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Rev Urol"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1038\/ncpuro0856","type":"journal-article","created":{"date-parts":[[2007,9,6]],"date-time":"2007-09-06T13:48:47Z","timestamp":1189086527000},"page":"492-497","source":"Crossref","is-referenced-by-count":12,"title":["Current management strategies for testicular microlithiasis"],"prefix":"10.1038","volume":"4","author":[{"given":"Kirubanand","family":"Jaganathan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shwan","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alastair","family":"Henderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhay","family":"Ran\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BFncpuro0856_CR1","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1542\/peds.46.5.785","volume":"46","author":"CJ Priebe Jr","year":"1970","unstructured":"Priebe CJ Jr and Garret R (1970) Testicular calcification in a 4-year-old boy. Pediatrics 46: 785\u2013788","journal-title":"Pediatrics"},{"key":"BFncpuro0856_CR2","doi-asserted-by":"publisher","first-page":"389","DOI":"10.7863\/jum.1987.6.7.389","volume":"6","author":"FJ Doherty","year":"1987","unstructured":"Doherty FJ et al. (1987) Testicular microlithiasis: a unique sonographic appearance. J Ultrasound Med 6: 389\u2013392","journal-title":"J Ultrasound Med"},{"key":"BFncpuro0856_CR3","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1148\/radiology.218.2.r01fe25359","volume":"218","author":"HF Bennett","year":"2001","unstructured":"Bennett HF et al. (2001) Testicular microlithiasis: US follow-up. Radiology 218: 359\u2013363","journal-title":"Radiology"},{"key":"BFncpuro0856_CR4","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1148\/radiology.192.3.8058947","volume":"192","author":"ML Backus","year":"1994","unstructured":"Backus ML et al. (1994) Testicular microlithiasis: imaging appearances and pathologic correlation. Radiology 192: 781\u2013785","journal-title":"Radiology"},{"key":"BFncpuro0856_CR5","doi-asserted-by":"publisher","first-page":"2126","DOI":"10.1007\/s003300101125","volume":"11","author":"F Cornud","year":"2001","unstructured":"Cornud F et al. (2001) Ultrasound findings in male hypofertility and impotence. Eur Radiol 11: 2126\u20132136","journal-title":"Eur Radiol"},{"key":"BFncpuro0856_CR6","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.1210\/jcem-25-10-1340","volume":"25","author":"RC Bieger","year":"1965","unstructured":"Bieger RC et al. (1965) Testicular intratubular bodies. J Clin Endocrinol Metab 25: 1340\u20131346","journal-title":"J Clin Endocrinol Metab"},{"key":"BFncpuro0856_CR7","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/S0022-5347(17)55318-5","volume":"124","author":"M Vegni-Talluri","year":"1980","unstructured":"Vegni-Talluri M et al. (1980) Testicular microliths: their origin and structure. J Urol 124: 105\u2013107","journal-title":"J Urol"},{"key":"BFncpuro0856_CR8","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1016\/S0022-5347(01)62364-4","volume":"160","author":"AA Renshaw","year":"1998","unstructured":"Renshaw AA (1998) Testicular calcifications: incidence, histology and proposed pathological criteria for testicular microlithiasis. J Urol 160: 1625\u20131628","journal-title":"J Urol"},{"key":"BFncpuro0856_CR9","doi-asserted-by":"publisher","first-page":"2061","DOI":"10.1016\/S0022-5347(05)65506-1","volume":"166","author":"AC Peterson","year":"2001","unstructured":"Peterson AC et al. (2001) The prevalence of testicular microlithiasis in an asymptomatic population of men 18 to 35 years old. J Urol 166: 2061\u20132064","journal-title":"J Urol"},{"key":"BFncpuro0856_CR10","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1016\/S0090-4295(01)00957-8","volume":"57","author":"M Derogee","year":"2001","unstructured":"Derogee M et al. (2001) Testicular microlithiasis, a premalignant condition: prevalence, histopathologic findings, and relation to testicular tumor. Urology 57: 1133\u20131137","journal-title":"Urology"},{"key":"BFncpuro0856_CR11","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1046\/j.1464-410X.2000.00786.x","volume":"86","author":"RJ Skyrme","year":"2000","unstructured":"Skyrme RJ et al. (2000) Testicular microlithiasis in a UK population: its incidence, associations and follow-up. BJU Int 86: 482\u2013485","journal-title":"BJU Int"},{"key":"BFncpuro0856_CR12","doi-asserted-by":"publisher","first-page":"1703","DOI":"10.2214\/ajr.175.6.1751703","volume":"175","author":"JE Cast","year":"2000","unstructured":"Cast JE et al. (2000) Testicular microlithiasis: prevalence and tumor risk in a population referred for scrotal sonography. AJR Am J Roentgenol 175: 1703\u20131706","journal-title":"AJR Am J Roentgenol"},{"key":"BFncpuro0856_CR13","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1002\/j.1939-4640.2001.tb02586.x","volume":"22","author":"S Von Eckardstein","year":"2001","unstructured":"Von Eckardstein S et al. (2001) Sonographic testicular microlithiasis as an indicator of premalignant conditions in normal and infertile men. J Androl 22: 818\u2013824","journal-title":"J Androl"},{"key":"BFncpuro0856_CR14","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1007\/s00247-002-0724-5","volume":"32","author":"AS Leenen","year":"2002","unstructured":"Leenen AS and Riebel TW (2002) Testicular microlithiasis in children: sonographic features and clinical implications. Pediatr Radiol 32: 575\u2013579","journal-title":"Pediatr Radiol"},{"key":"BFncpuro0856_CR15","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s00330-006-0296-0","volume":"17","author":"NAC Miller","year":"2007","unstructured":"Miller NAC et al. (2007) Testicular calcification and microlithiasis: association with primary intra-testicular malignancy in 3,477 patients. Eur Radiol 17: 363\u2013369","journal-title":"Eur Radiol"},{"key":"BFncpuro0856_CR16","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/0090-4295(82)90611-2","volume":"19","author":"U Ikinger","year":"1982","unstructured":"Ikinger U et al. (1982) Microcalcifications in testicular malignancy: diagnostic tool in occult tumor? Urology 19: 525\u2013528","journal-title":"Urology"},{"key":"BFncpuro0856_CR17","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/S0090-4295(98)00438-5","volume":"53","author":"JP Ganem","year":"1999","unstructured":"Ganem JP et al. (1999) Testicular microlithiasis is associated with testicular pathology. Urology 53: 209\u2013213","journal-title":"Urology"},{"key":"BFncpuro0856_CR18","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1002\/1097-0142(19860315)57:6<1254::AID-CNCR2820570632>3.0.CO;2-2","volume":"57","author":"KP Dieckmann","year":"1986","unstructured":"Dieckmann KP et al. (1986) Bilateral testicular germ cell tumors. Report of nine cases and review of the literature. Cancer 57: 1254\u20131258","journal-title":"Cancer"},{"key":"BFncpuro0856_CR19","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1097\/01.ju.0000087820.94991.21","volume":"170","author":"M Holm","year":"2003","unstructured":"Holm M et al. (2003) Increased risk of carcinoma in situ in patients with testicular germ cell tumor with ultrasonic microlithiasis in the contralateral testicle. J Urol 170: 1163\u20131167","journal-title":"J Urol"},{"key":"BFncpuro0856_CR20","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/S0094-0143(21)01352-5","volume":"9","author":"NE Skakkebaek","year":"1982","unstructured":"Skakkebaek NE et al. (1982) Carcinoma-in-situ of the undescended testis. Urol Clin North Am 9: 377\u2013385","journal-title":"Urol Clin North Am"},{"key":"BFncpuro0856_CR21","doi-asserted-by":"publisher","first-page":"497","DOI":"10.2214\/ajr.180.2.1800497","volume":"180","author":"AM Bach","year":"2003","unstructured":"Bach AM et al. (2003) Is there an increased incidence of contralateral testicular cancer in patients with intratesticular microlithiasis? AJR Am J Roentgenol 180: 497\u2013500","journal-title":"AJR Am J Roentgenol"},{"key":"BFncpuro0856_CR22","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1159\/000083279","volume":"74","author":"MA Pourbagher","year":"2005","unstructured":"Pourbagher MA et al. (2005) Follow-up of testicular microlithiasis for subsequent testicular cancer development. Urol Int 74: 108\u2013112","journal-title":"Urol Int"},{"key":"BFncpuro0856_CR23","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1016\/S0022-5347(01)62723-X","volume":"160","author":"PD Furness III","year":"1998","unstructured":"Furness PD III et al. (1998) Multi-institutional study of testicular microlithiasis in childhood: a benign or premalignant condition? J Urol 160: 1151\u20131154","journal-title":"J Urol"},{"key":"BFncpuro0856_CR24","doi-asserted-by":"publisher","first-page":"971","DOI":"10.2214\/ajr.164.4.7726059","volume":"164","author":"N McEniff","year":"1995","unstructured":"McEniff N et al. (1995) Yolk sac tumor of the testis discovered on a routine annual sonogram in a boy with testicular microlithiasis. AJR Am J Roentgenol 164: 971\u2013972","journal-title":"AJR Am J Roentgenol"},{"key":"BFncpuro0856_CR25","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1016\/S0022-5347(01)66482-6","volume":"155","author":"TC Winter III","year":"1996","unstructured":"Winter TC III et al. (1996) Testicular carcinoma in a patient with previously demonstrated testicular microlithiasis. J Urol 155: 648","journal-title":"J Urol"},{"key":"BFncpuro0856_CR26","doi-asserted-by":"publisher","first-page":"889","DOI":"10.2214\/ajr.167.4.8819375","volume":"167","author":"DP Frush","year":"1996","unstructured":"Frush DP et al. (1996) Testicular microlithiasis and subsequent development of metastatic germ cell tumor. AJR Am J Roentgenol 167: 889\u2013890","journal-title":"AJR Am J Roentgenol"},{"key":"BFncpuro0856_CR27","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1080\/003655901750292042","volume":"35","author":"PA Cornford","year":"2001","unstructured":"Cornford PA et al. (2001) Testicular microlithiasis needs long-term surveillance. Scand J Urol Nephrol 35: 243\u2013244","journal-title":"Scand J Urol Nephrol"},{"key":"BFncpuro0856_CR28","first-page":"521","volume":"56","author":"MA Ortiz Gorraiz","year":"2003","unstructured":"Ortiz Gorraiz MA et al. (2003) Testicular microlithiasis and testicular cancer [Spanish]. Arch Esp Urol 56: 521\u2013524","journal-title":"Arch Esp Urol"},{"key":"BFncpuro0856_CR29","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1046\/j.1445-2197.2003.t01-1-02617.x","volume":"73","author":"N Lawrentschuk","year":"2003","unstructured":"Lawrentschuk N et al. (2003) Testicular microlithiasis: a case report and review of the literature. ANZ J Surg 73: 364\u2013366","journal-title":"ANZ J Surg"},{"key":"BFncpuro0856_CR30","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1259\/bjr.73.869.10884745","volume":"73","author":"K Thomas","year":"2000","unstructured":"Thomas K et al. (2000) The incidence and significance of testicular microlithiasis in a subfertile population. Br J Radiol 73: 494\u2013497","journal-title":"Br J Radiol"},{"key":"BFncpuro0856_CR31","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1159\/000281397","volume":"43","author":"I Sasagawa","year":"1988","unstructured":"Sasagawa I et al. (1988) Testicular microlithiasis in male infertility. Urol Int 43: 368\u2013369","journal-title":"Urol Int"},{"key":"BFncpuro0856_CR32","doi-asserted-by":"publisher","first-page":"1618","DOI":"10.1016\/S0022-5347(05)68180-3","volume":"162","author":"FH Pierik","year":"1999","unstructured":"Pierik FH et al. (1999) Is routine scrotal ultrasound advantageous in infertile men? J Urol 162: 1618\u20131620","journal-title":"J Urol"},{"key":"BFncpuro0856_CR33","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1016\/S0015-0282(16)41956-4","volume":"27","author":"A Schantz","year":"1976","unstructured":"Schantz A and Milsten R (1976) Testicular microlithiasis with sterility. Fertil Steril 27: 801\u2013805","journal-title":"Fertil Steril"},{"key":"BFncpuro0856_CR34","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1111\/j.1464-410X.1993.tb00702.x","volume":"72","author":"JM Moran","year":"1993","unstructured":"Moran JM et al. (1993) Idiopathic testicular microlithiasis: ultrastructural study. Br J Urol 72: 252\u2013253","journal-title":"Br J Urol"},{"key":"BFncpuro0856_CR35","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1097\/01.ju.0000093440.47816.88","volume":"171","author":"CA de Gouveia Brazao","year":"2004","unstructured":"de Gouveia Brazao CA et al. (2004) Bilateral testicular microlithiasis predicts the presence of the precursor of testicular germ cell tumors in subfertile men. J Urol 171: 158\u2013160","journal-title":"J Urol"},{"key":"BFncpuro0856_CR36","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.urology.2004.10.020","volume":"66","author":"DA Husmann","year":"2005","unstructured":"Husmann DA (2005) Cryptorchidism and its relationship to testicular neoplasia and microlithiasis. Urology 66: 424\u2013426","journal-title":"Urology"},{"key":"BFncpuro0856_CR37","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1016\/S0022-5347(17)66088-9","volume":"81","author":"HE Campbell","year":"1959","unstructured":"Campbell HE (1959) The incidence of malignant growth of the undescended testicle: a reply and re-evaluation. J Urol 81: 663\u2013668","journal-title":"J Urol"}],"container-title":["Nature Clinical Practice Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ncpuro0856.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ncpuro0856","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/ncpuro0856","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/ncpuro0856.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T19:36:06Z","timestamp":1708198566000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ncpuro0856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["BFncpuro0856"],"URL":"https:\/\/doi.org\/10.1038\/ncpuro0856","relation":{},"ISSN":["1743-4270","1743-4289"],"issn-type":[{"value":"1743-4270","type":"print"},{"value":"1743-4289","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}