{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T13:01:24Z","timestamp":1761310884698},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"81","license":[{"start":{"date-parts":[[1972,7,1]],"date-time":"1972-07-01T00:00:00Z","timestamp":78796800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nature New Biology"],"published-print":{"date-parts":[[1972,7]]},"DOI":"10.1038\/newbio238087a0","type":"journal-article","created":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T13:35:34Z","timestamp":1374672934000},"page":"87-88","source":"Crossref","is-referenced-by-count":11,"title":["Conformational Requirements of Acetylcholine Analogues and Local Anaesthetics"],"prefix":"10.1038","volume":"238","author":[{"given":"HENRY G.","family":"MAUTNER","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DAVID D.","family":"DEXTER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BARBARA W.","family":"LOW","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BFnewbio238087a0_CR1","first-page":"57","volume":"49","author":"D Nachmansohn","year":"1955","unstructured":"Nachmansohn, D., Harvey Lectures, 49, 57, 1953\/1954 (1955).","journal-title":"Harvey Lectures"},{"key":"BFnewbio238087a0_CR2","unstructured":"Nachmansohn, D., The Chemical and Molecular Basis of Nerve Activity (Academic Press, New York, 1959)."},{"key":"BFnewbio238087a0_CR3","first-page":"359","volume":"342","author":"E Bartels","year":"1965","unstructured":"Bartels, E., and Nachmansohn, D., Biochem. Ztschr., 342, 359 (1965).","journal-title":"Biochem. Ztschr."},{"key":"BFnewbio238087a0_CR4","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/0926-6585(65)90103-2","volume":"109","author":"E Bartels","year":"1965","unstructured":"Bartels, E., Biochim. Biophys. Acta, 109, 194 (1965).","journal-title":"Biochim. Biophys. Acta"},{"key":"BFnewbio238087a0_CR5","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1038\/230439a0","volume":"230","author":"RW Baker","year":"1971","unstructured":"Baker, R. W., Chothia, C. H., Pauling, P., and Petcher, T. J., Nature, 230, 439 (1971).","journal-title":"Nature"},{"key":"BFnewbio238087a0_CR6","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1038\/210907a0","volume":"210","author":"FG Canepa","year":"1966","unstructured":"Canepa, F. G., Pauling, P., and S\u00f6rum, H., Nature, 210, 907 (1966).","journal-title":"Nature"},{"key":"BFnewbio238087a0_CR7","first-page":"537","volume":"15","author":"CCJ Culvenor","year":"1966","unstructured":"Culvenor, C. C. J., and Ham, N. S., Chem. Commun., 15, 537 (1966).","journal-title":"Chem. Commun."},{"key":"BFnewbio238087a0_CR8","first-page":"306","volume":"270","author":"Y Barrans","year":"1970","unstructured":"Barrans, Y., and Clastre, J., Compt. Rend. Acad. Sci., 270, C., 306 (1970).","journal-title":"Compt. Rend. Acad. Sci."},{"key":"BFnewbio238087a0_CR9","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1038\/217035a0","volume":"217","author":"M Sundaralingam","year":"1968","unstructured":"Sundaralingam, M., Nature, 217, 35 (1968).","journal-title":"Nature"},{"key":"BFnewbio238087a0_CR10","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/0006-291X(70)90580-2","volume":"39","author":"R Beall","year":"1970","unstructured":"Beall, R., Herdklotz, J., and Sass, R. L., Biochem. Biophys. Res. Comm., 39, 329 (1970).","journal-title":"Biochem. Biophys. Res. Comm."},{"key":"BFnewbio238087a0_CR11","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1073\/pnas.63.4.1253","volume":"63","author":"E Shefter","year":"1969","unstructured":"Shefter, E., and Mautner, H. G., Proc. US Nat. Acad. Sci., 63, 1253 (1969).","journal-title":"Proc. US Nat. Acad. Sci."},{"key":"BFnewbio238087a0_CR12","volume-title":"Amer. Cryst. Assoc.","author":"D Dexter","year":"1970","unstructured":"Dexter, D., Amer. Cryst. Assoc. Winter Meeting (March 1970), F-8."},{"key":"BFnewbio238087a0_CR13","unstructured":"Dexter, D., Acta Cryst. (in the press)."},{"key":"BFnewbio238087a0_CR14","first-page":"2151","volume":"26","author":"RJ Cushley","year":"1970","unstructured":"Cushley, R. J., and Mautner, H. G., Terra, 26, 2151 (1970).","journal-title":"Terra"},{"key":"BFnewbio238087a0_CR15","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1016\/0006-2952(64)90034-6","volume":"13","author":"KA Scott","year":"1964","unstructured":"Scott, K. A., and Mautner, H. G., Biochem. Pharmacol., 13, 907 (1964). ibid., 16, 1903 (1967).","journal-title":"Biochem. Pharmacol."},{"key":"BFnewbio238087a0_CR16","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/0006-2952(66)90059-1","volume":"15","author":"HG Mautner","year":"1966","unstructured":"Mautner, H. G., Bartels, E., and Webb, G. D., Biochem. Pharmacol., 15, 187 (1966).","journal-title":"Biochem. Pharmacol."},{"key":"BFnewbio238087a0_CR17","doi-asserted-by":"publisher","first-page":"271s","DOI":"10.1085\/jgp.54.1.271","volume":"54","author":"HG Mautner","year":"1969","unstructured":"Mautner, H. G., J. Gen. Physiol., 54, Pt. 1, 271s (1969).","journal-title":"J. Gen. Physiol."},{"key":"BFnewbio238087a0_CR18","doi-asserted-by":"publisher","first-page":"2105","DOI":"10.1016\/0006-2952(66)90240-1","volume":"15","author":"GD Webb","year":"1966","unstructured":"Webb, G. D., and Mautner, H. G., Biochem. Pharmacol., 15, 2105 (1966).","journal-title":"Biochem. Pharmacol."},{"key":"BFnewbio238087a0_CR19","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1126\/science.155.3769.1569","volume":"155","author":"P Rosenberg","year":"1967","unstructured":"Rosenberg, P., and Mautner, H. G., Science, 155, 1569 (1967).","journal-title":"Science"},{"key":"BFnewbio238087a0_CR20","doi-asserted-by":"publisher","first-page":"4447","DOI":"10.1021\/ja00717a050","volume":"92","author":"I Wallmark","year":"1970","unstructured":"Wallmark, I., Krackov, M. H., and Mautner, H. G., J. Amer. Chem. Soc, 92, 4447 (1970).","journal-title":"J. Amer. Chem. Soc"},{"key":"BFnewbio238087a0_CR21","doi-asserted-by":"publisher","first-page":"2633","DOI":"10.1021\/bi00815a011","volume":"9","author":"GR Hillman","year":"1970","unstructured":"Hillman, G. R., and Mautner, H. G., Biochem., 9, 2633 (1970).","journal-title":"Biochem."},{"key":"BFnewbio238087a0_CR22","first-page":"569","volume":"31","author":"A Makriyannis","year":"1972","unstructured":"Makriyannis, A., Sullivan, R. F., and Mautner, H. G., Fed. Proc, 31, 569 Abs (1972).","journal-title":"Fed. Proc"},{"key":"BFnewbio238087a0_CR23","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1098\/rspb.1967.0035","volume":"167","author":"CCF Blake","year":"1967","unstructured":"Blake, C. C. F., Johnson, L. N., Mair, G. A., North, A. C. T., Phillips, D. C., and Sarma, V. R., Proc. Roy. Soc, B, 167, 378 (1967).","journal-title":"Proc. Roy. Soc"},{"key":"BFnewbio238087a0_CR24","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1021\/jm00271a019","volume":"15","author":"JG Cannon","year":"1972","unstructured":"Cannon, J. G., Rege, A. B., Gruen, T. L., and Long, J. P., J. Med. Chem., 15, 71 (1972).","journal-title":"J. Med. Chem."}],"container-title":["Nature New Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/newbio238087a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/newbio238087a0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/newbio238087a0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T20:39:46Z","timestamp":1684442386000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/newbio238087a0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,7]]},"references-count":24,"journal-issue":{"issue":"81","published-print":{"date-parts":[[1972,7]]}},"alternative-id":["BFnewbio238087a0"],"URL":"https:\/\/doi.org\/10.1038\/newbio238087a0","relation":{},"ISSN":["0090-0028","2058-1092"],"issn-type":[{"value":"0090-0028","type":"print"},{"value":"2058-1092","type":"electronic"}],"subject":[],"published":{"date-parts":[[1972,7]]}}}