{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:16:54Z","timestamp":1792725414536,"version":"4.5.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2012,9,30]],"date-time":"2012-09-30T00:00:00Z","timestamp":1348963200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Genet"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1038\/ng.2425","type":"journal-article","created":{"date-parts":[[2012,9,30]],"date-time":"2012-09-30T19:46:08Z","timestamp":1349034368000},"page":"1260-1264","source":"Crossref","is-referenced-by-count":105,"title":["CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development"],"prefix":"10.1038","volume":"44","author":[{"given":"Ganeshwaran H","family":"Mochida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay S","family":"Ganesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria I","family":"de Michelena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kutay D","family":"Atabay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie L","family":"Kathrein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsuan-Ting","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R Sean","family":"Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jillian M","family":"Felie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Rakiec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Gleason","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony D","family":"Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athar N","family":"Malik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda J","family":"Barry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer N","family":"Partlow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Hann","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurie J","family":"Glader","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A James","family":"Barkovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William B","family":"Dobyns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard I","family":"Zon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher A","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,9,30]]},"reference":[{"key":"BFng2425_CR1","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1242\/jcs.114.13.2395","volume":"114","author":"TL Howard","year":"2001","unstructured":"Howard, T.L., Stauffer, D.R., Degnin, C.R. & Hollenberg, S.M. CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins. J. Cell Sci. 114, 2395\u20132404 (2001).","journal-title":"J. Cell Sci."},{"key":"BFng2425_CR2","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.ygeno.2006.04.003","volume":"88","author":"HT Tsang","year":"2006","unstructured":"Tsang, H.T. et al. A systematic analysis of human CHMP protein interactions: additional MIT domain\u2013containing proteins bind to multiple components of the human ESCRT III complex. Genomics 88, 333\u2013346 (2006).","journal-title":"Genomics"},{"key":"BFng2425_CR3","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1242\/jcs.114.13.2383","volume":"114","author":"DR Stauffer","year":"2001","unstructured":"Stauffer, D.R., Howard, T.L., Nyun, T. & Hollenberg, S.M. CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression. J. Cell Sci. 114, 2383\u20132393 (2001).","journal-title":"J. Cell Sci."},{"key":"BFng2425_CR4","doi-asserted-by":"crossref","unstructured":"1000 Genomes Project Consortium. A map of human genome variation from population-scale sequencing. Nature 467, 1061\u20131073 (2010).","DOI":"10.1038\/nature09534"},{"key":"BFng2425_CR5","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1038\/nature06172","volume":"449","author":"MD Stuchell-Brereton","year":"2007","unstructured":"Stuchell-Brereton, M.D. et al. ESCRT-III recognition by VPS4 ATPases. Nature 449, 740\u2013744 (2007).","journal-title":"Nature"},{"key":"BFng2425_CR6","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1038\/nature08910","volume":"463","author":"G Scita","year":"2010","unstructured":"Scita, G. & Di Fiore, P.P. The endocytic matrix. Nature 463, 464\u2013473 (2010).","journal-title":"Nature"},{"key":"BFng2425_CR7","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1038\/nature02060","volume":"425","author":"AV Molofsky","year":"2003","unstructured":"Molofsky, A.V. et al. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425, 962\u2013967 (2003).","journal-title":"Nature"},{"key":"BFng2425_CR8","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1177\/0883073811420148","volume":"26","author":"C Garel","year":"2011","unstructured":"Garel, C., Fallet-Bianco, C. & Guibaud, L. The fetal cerebellum: development and common malformations. J. Child Neurol. 26, 1483\u20131492 (2011).","journal-title":"J. Child Neurol."},{"key":"BFng2425_CR9","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1038\/16476","volume":"397","author":"JJ Jacobs","year":"1999","unstructured":"Jacobs, J.J., Kieboom, K., Marino, S., DePinho, R.A. & van Lohuizen, M. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397, 164\u2013168 (1999).","journal-title":"Nature"},{"key":"BFng2425_CR10","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1038\/nature02385","volume":"428","author":"C Leung","year":"2004","unstructured":"Leung, C. et al. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature 428, 337\u2013341 (2004).","journal-title":"Nature"},{"key":"BFng2425_CR11","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1101\/gad.8.7.757","volume":"8","author":"NM van der Lugt","year":"1994","unstructured":"van der Lugt, N.M. et al. Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. Genes Dev. 8, 757\u2013769 (1994).","journal-title":"Genes Dev."},{"key":"BFng2425_CR12","doi-asserted-by":"publisher","first-page":"5774","DOI":"10.1523\/JNEUROSCI.3452-04.2005","volume":"25","author":"D Zencak","year":"2005","unstructured":"Zencak, D. et al. Bmi1 loss produces an increase in astroglial cells and a decrease in neural stem cell population and proliferation. J. Neurosci. 25, 5774\u20135783 (2005).","journal-title":"J. Neurosci."},{"key":"BFng2425_CR13","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1101\/gr.229102","volume":"12","author":"WJ Kent","year":"2002","unstructured":"Kent, W.J. et al. The human genome browser at UCSC. Genome Res. 12, 996\u20131006 (2002).","journal-title":"Genome Res."},{"key":"BFng2425_CR14","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1038\/75514","volume":"25","author":"DF Gudbjartsson","year":"2000","unstructured":"Gudbjartsson, D.F., Jonasson, K., Frigge, M.L. & Kong, A. Allegro, a new computer program for multipoint linkage analysis. Nat. Genet. 25, 12\u201313 (2000).","journal-title":"Nat. Genet."},{"key":"BFng2425_CR15","doi-asserted-by":"crossref","unstructured":"Rozen, S. & Skaletsky, H.J. Primer3 on the WWW for general users and for biologist programmers. in Bioinformatics Methods and Protocols: Methods in Molecular Biology (eds. Krawetz, S. & Misener, S.) 365\u2013386 (Humana Press, Totowa, New Jersey, 2000).","DOI":"10.1385\/1-59259-192-2:365"},{"key":"BFng2425_CR16","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/0022-2836(91)90380-O","volume":"220","author":"S Brunak","year":"1991","unstructured":"Brunak, S., Engelbrecht, J. & Knudsen, S. Prediction of human mRNA donor and acceptor sites from the DNA sequence. J. Mol. Biol. 220, 49\u201365 (1991).","journal-title":"J. Mol. Biol."},{"key":"BFng2425_CR17","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1016\/j.neuron.2008.11.029","volume":"60","author":"SW Flavell","year":"2008","unstructured":"Flavell, S.W. et al. Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity\u2013dependent polyadenylation site selection. Neuron 60, 1022\u20131038 (2008).","journal-title":"Neuron"},{"key":"BFng2425_CR18","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/aja.1002030302","volume":"203","author":"CB Kimmel","year":"1995","unstructured":"Kimmel, C.B., Ballard, W.W., Kimmel, S.R., Ullmann, B. & Schilling, T.F. Stages of embryonic development of the zebrafish. Dev. Dyn. 203, 253\u2013310 (1995).","journal-title":"Dev. Dyn."},{"key":"BFng2425_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-213X-6-1","volume":"6","author":"V Link","year":"2006","unstructured":"Link, V., Shevchenko, A. & Heisenberg, C.P. Proteomics of early zebrafish embryos. BMC Dev. Biol. 6, 1 (2006).","journal-title":"BMC Dev. Biol."},{"key":"BFng2425_CR20","doi-asserted-by":"crossref","unstructured":"Bilimoria, P.M. & Bonni, A. Cultures of cerebellar granule neurons. CSH Protoc. 2008, pdb prot5107 (2008).","DOI":"10.1101\/pdb.prot5107"}],"container-title":["Nature Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ng.2425.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ng.2425","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ng.2425.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T20:49:54Z","timestamp":1684442994000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ng.2425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,30]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["BFng2425"],"URL":"https:\/\/doi.org\/10.1038\/ng.2425","relation":{},"ISSN":["1061-4036","1546-1718"],"issn-type":[{"value":"1061-4036","type":"print"},{"value":"1546-1718","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,30]]}}}