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A.C. is a paid member of the Scientific Advisory Board of Biogen Idec. These potential conflicts of interest are managed by the policies of Johns Hopkins University School of Medicine. D.I.C. receives genotyping and collaborative scientific support from Amgen and receives support for genetic analysis from AstraZeneca. J.F.F. worked until 2013 in ErasmusAGE, a center for ageing research across the life course funded by Nestl\u00e9 Nutrition (Nestec, Ltd), Metagenics, Inc., and AXA. H.J.G. currently works for Illumina. T.J. is an employee of and owns stock in GlaxoSmithKline. B.M.P. serves on the DSMB for a clinical trial funded by the manufacturer (Zoll LifeCor) and on the Steering Committee for the Yale Open Data Access Project funded by Johnson & Johnson. P.M.R. receives genotyping and collaborative scientific support from Amgen and receives support for genetic analysis from AstraZeneca. 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