{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:41:15Z","timestamp":1790880075728,"version":"4.1.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2004,1,18]],"date-time":"2004-01-18T00:00:00Z","timestamp":1074384000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Genet"],"published-print":{"date-parts":[[2004,2]]},"DOI":"10.1038\/ng1292","type":"journal-article","created":{"date-parts":[[2004,1,18]],"date-time":"2004-01-18T13:46:50Z","timestamp":1074433610000},"page":"172-177","source":"Crossref","is-referenced-by-count":130,"title":["A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1"],"prefix":"10.1038","volume":"36","author":[{"given":"Kogo","family":"Takamiya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vassiliki","family":"Kostourou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalini","family":"Jadeja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georges","family":"Chalepakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J","family":"Scambler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard L","family":"Huganir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf H","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2004,1,18]]},"reference":[{"key":"BFng1292_CR1","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1038\/nrg758","volume":"3","author":"E Fuchs","year":"2002","unstructured":"Fuchs, E. & Raghavan, S. Getting under the skin of epidermal morphogenesis. Nat. Rev. Genet. 3, 199\u2013209 (2002).","journal-title":"Nat. Rev. Genet."},{"key":"BFng1292_CR2","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1038\/nrg842","volume":"3","author":"S Vainio","year":"2002","unstructured":"Vainio, S. & Lin, Y. Coordinating early kidney development: lessons from gene targeting. Nat. Rev. Genet. 3, 533\u2013543 (2002).","journal-title":"Nat. Rev. Genet."},{"key":"BFng1292_CR3","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1038\/ng1142","volume":"34","author":"L McGregor","year":"2003","unstructured":"McGregor, L. et al. Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1\/Fras1 encoding a putative extracellular matrix protein. Nat. Genet. 34, 203\u2013208 (2003).","journal-title":"Nat. Genet."},{"key":"BFng1292_CR4","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1038\/ng1168","volume":"34","author":"S Vrontou","year":"2003","unstructured":"Vrontou, S. et al. Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice. Nat. Genet. 34, 209\u2013214 (2003).","journal-title":"Nat. Genet."},{"key":"BFng1292_CR5","doi-asserted-by":"publisher","first-page":"6930","DOI":"10.1523\/JNEUROSCI.19-16-06930.1999","volume":"19","author":"H Dong","year":"1999","unstructured":"Dong, H. et al. Characterization of the glutamate receptor-interacting proteins GRIP1 and GRIP2. J. Neurosci. 19, 6930\u20136941 (1999).","journal-title":"J. Neurosci."},{"key":"BFng1292_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1146\/annurev.neuro.24.1.1","volume":"24","author":"M Sheng","year":"2001","unstructured":"Sheng, M. & Sala, C. PDZ domains and the organization of supramolecular complexes. Annu. Rev. Neurosci. 24, 1\u201329 (2001).","journal-title":"Annu. Rev. Neurosci."},{"key":"BFng1292_CR7","doi-asserted-by":"publisher","first-page":"5699","DOI":"10.1074\/jbc.R100065200","volume":"277","author":"AY Hung","year":"2002","unstructured":"Hung, A.Y. & Sheng, M. PDZ domains: structural modules for protein complex assembly. J. Biol. Chem. 277, 5699\u20135702 (2002).","journal-title":"J. Biol. Chem."},{"key":"BFng1292_CR8","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1242\/jcs.114.18.3219","volume":"114","author":"BZ Harris","year":"2001","unstructured":"Harris, B.Z. & Lim, W.A. Mechanism and role of PDZ domains in signaling complex assembly. J. Cell Sci. 114, 3219\u20133231 (2001).","journal-title":"J. Cell Sci."},{"key":"BFng1292_CR9","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1038\/nature743","volume":"417","author":"M Setou","year":"2002","unstructured":"Setou, M. et al. Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. Nature 417, 83\u201387 (2002).","journal-title":"Nature"},{"key":"BFng1292_CR10","doi-asserted-by":"publisher","first-page":"6816","DOI":"10.1073\/pnas.092130099","volume":"99","author":"F Bladt","year":"2002","unstructured":"Bladt, F., Tafuri, A., Gelkop, S., Langille, L. & Pawson, T. Epidermolysis bullosa and embryonic lethality in mice lacking the multi-PDZ domain protein GRIP1. Proc. Natl. Acad. Sci. USA 99, 6816\u20136821 (2002).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFng1292_CR11","doi-asserted-by":"publisher","first-page":"10769","DOI":"10.1074\/jbc.272.16.10769","volume":"272","author":"E Tillet","year":"1997","unstructured":"Tillet, E., Ruggiero, F., Nishiyama, A. & Stallcup, W.B. The membrane-spanning proteoglycan NG2 binds to collagens V and VI through the central nonglobular domain of its core protein. J. Biol. Chem. 272, 10769\u201310776 (1997).","journal-title":"J. Biol. Chem."},{"key":"BFng1292_CR12","doi-asserted-by":"publisher","first-page":"3590","DOI":"10.1074\/jbc.M210010200","volume":"278","author":"J Stegmuller","year":"2003","unstructured":"Stegmuller, J., Werner, H., Nave, K.A. & Trotter, J. The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling. J. Biol. Chem. 278, 3590\u20133598 (2003).","journal-title":"J. Biol. Chem."},{"key":"BFng1292_CR13","doi-asserted-by":"crossref","first-page":"3641","DOI":"10.1242\/jcs.112.21.3641","volume":"112","author":"S Heinonen","year":"1999","unstructured":"Heinonen, S. et al. Targeted inactivation of the type VII collagen gene (Col7a1) in mice results in severe blistering phenotype: a model for recessive dystrophic epidermolysis bullosa. J. Cell Sci. 112 (Pt 21), 3641\u20133648 (1999).","journal-title":"J. Cell Sci."},{"key":"BFng1292_CR14","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1111\/j.1399-0004.1990.tb03539.x","volume":"37","author":"RM Winter","year":"1990","unstructured":"Winter, R.M. Fraser syndrome and mouse 'bleb' mutants. Clin. Genet. 37, 494\u2013495 (1990).","journal-title":"Clin. Genet."},{"key":"BFng1292_CR15","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1097\/00019605-199404000-00001","volume":"3","author":"S Darling","year":"1994","unstructured":"Darling, S. & Gossler, A. A mouse model for Fraser syndrome? Clin. Dysmorphol. 3, 91\u201395 (1994).","journal-title":"Clin. Dysmorphol."},{"key":"BFng1292_CR16","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1002\/1097-0177(2000)9999:9999<::AID-DVDY1030>3.0.CO;2-S","volume":"219","author":"JJ Swiergiel","year":"2000","unstructured":"Swiergiel, J.J., Funderburgh, J.L., Justice, M.J. & Conrad, G.W. Developmental eye and neural tube defects in the eye blebs mouse. Dev. Dyn. 219, 21\u201327 (2000).","journal-title":"Dev. Dyn."},{"key":"BFng1292_CR17","doi-asserted-by":"publisher","first-page":"8424","DOI":"10.1073\/pnas.90.18.8424","volume":"90","author":"A Nagy","year":"1993","unstructured":"Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W. & Roder, J.C. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90, 8424\u20138428 (1993).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFng1292_CR18","doi-asserted-by":"publisher","first-page":"5096","DOI":"10.1073\/pnas.88.12.5096","volume":"88","author":"PS Jat","year":"1991","unstructured":"Jat, P.S. et al. Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. Proc. Natl. Acad. Sci. USA 88, 5096\u20135100 (1991).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFng1292_CR19","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1083\/jcb.137.3.729","volume":"137","author":"CM DiPersio","year":"1997","unstructured":"DiPersio, C.M., Hodivala-Dilke, K.M., Jaenisch, R., Kreidberg, J.A. & Hynes, R.O. \u03b13\u03b21 Integrin is required for normal development of the epidermal basement membrane. J. Cell Biol. 137, 729\u2013742 (1997).","journal-title":"J. Cell Biol."},{"key":"BFng1292_CR20","first-page":"29","volume":"45","author":"KP Hummel","year":"1971","unstructured":"Hummel, K.P. & Chapman, D.B. Atrichosis (at) appears to be closely linked with eyeblebs (eb). Mouse News Lett. 45, 29 (1971).","journal-title":"Mouse News Lett."}],"container-title":["Nature Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ng1292.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ng1292","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ng1292.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T18:01:21Z","timestamp":1684432881000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ng1292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1,18]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,2]]}},"alternative-id":["BFng1292"],"URL":"https:\/\/doi.org\/10.1038\/ng1292","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1017265.202371","asserted-by":"object"}]},"ISSN":["1061-4036","1546-1718"],"issn-type":[{"value":"1061-4036","type":"print"},{"value":"1546-1718","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,1,18]]}}}