{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:58:28Z","timestamp":1791874708332,"version":"4.3.4"},"reference-count":57,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2014,9,14]],"date-time":"2014-09-14T00:00:00Z","timestamp":1410652800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2014,9,14]],"date-time":"2014-09-14T00:00:00Z","timestamp":1410652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Immunol"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1038\/ni.2987","type":"journal-article","created":{"date-parts":[[2014,9,14]],"date-time":"2014-09-14T18:15:10Z","timestamp":1410718510000},"page":"1017-1025","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":981,"title":["Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens"],"prefix":"10.1038","volume":"15","author":[{"given":"Nora","family":"Branzk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Lubojemska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E","family":"Hardison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximiliano G","family":"Gutierrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon D","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venizelos","family":"Papayannopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,9,14]]},"reference":[{"key":"BFni2987_CR1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1046\/j.1462-5822.1999.00002.x","volume":"1","author":"S Scianimanico","year":"1999","unstructured":"Scianimanico, S. et al. Impaired recruitment of the small GTPase rab7 correlates with the inhibition of phagosome maturation by Leishmania donovani promastigotes. Cell. Microbiol. 1, 19\u201332 (1999).","journal-title":"Cell. Microbiol."},{"key":"BFni2987_CR2","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1038\/sj.emboj.7600594","volume":"24","author":"BN Gantner","year":"2005","unstructured":"Gantner, B.N., Simmons, R.M. & Underhill, D.M. Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. EMBO J. 24, 1277\u20131286 (2005).","journal-title":"EMBO J."},{"key":"BFni2987_CR3","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1038\/nature10071","volume":"472","author":"HS Goodridge","year":"2011","unstructured":"Goodridge, H.S. et al. Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature 472, 471\u2013475 (2011).","journal-title":"Nature"},{"key":"BFni2987_CR4","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/nrmicro2711","volume":"10","author":"NA Gow","year":"2012","unstructured":"Gow, N.A., van de Veerdonk, F.L., Brown, A.J. & Netea, M.G. Candida albicans morphogenesis and host defence: discriminating invasion from colonization. Nat. Rev. Microbiol. 10, 112\u2013122 (2012).","journal-title":"Nat. Rev. Microbiol."},{"key":"BFni2987_CR5","doi-asserted-by":"crossref","first-page":"3578","DOI":"10.4049\/jimmunol.0901323","volume":"183","author":"S Joly","year":"2009","unstructured":"Joly, S. et al. Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome. J. Immunol. 183, 3578\u20133581 (2009).","journal-title":"J. Immunol."},{"key":"BFni2987_CR6","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1097\/MCC.0b013e32833e84d2","volume":"16","author":"MC Arendrup","year":"2010","unstructured":"Arendrup, M.C. Epidemiology of invasive candidiasis. Curr. Opin. Crit. Care 16, 445\u2013452 (2010).","journal-title":"Curr. Opin. Crit. Care"},{"key":"BFni2987_CR7","first-page":"14","volume":"3","author":"CY Low","year":"2011","unstructured":"Low, C.Y. & Rotstein, C. Emerging fungal infections in immunocompromised patients. F1000 Med. Rep. 3, 14 (2011).","journal-title":"F1000 Med. Rep."},{"key":"BFni2987_CR8","doi-asserted-by":"crossref","first-page":"e1000639","DOI":"10.1371\/journal.ppat.1000639","volume":"5","author":"CF Urban","year":"2009","unstructured":"Urban, C.F. et al. Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans. PLoS Pathog. 5, e1000639 (2009).","journal-title":"PLoS Pathog."},{"key":"BFni2987_CR9","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.immuni.2010.11.011","volume":"33","author":"N Borregaard","year":"2010","unstructured":"Borregaard, N. Neutrophils, from marrow to microbes. Immunity 33, 657\u2013670 (2010).","journal-title":"Immunity"},{"key":"BFni2987_CR10","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1146\/annurev-immunol-020711-074942","volume":"30","author":"B Amulic","year":"2012","unstructured":"Amulic, B., Cazalet, C., Hayes, G.L., Metzler, K.D. & Zychlinsky, A. Neutrophil function: from mechanisms to disease. Annu. Rev. Immunol. 30, 459\u2013489 (2012).","journal-title":"Annu. Rev. Immunol."},{"key":"BFni2987_CR11","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1126\/science.1092385","volume":"303","author":"V Brinkmann","year":"2004","unstructured":"Brinkmann, V. et al. Neutrophil extracellular traps kill bacteria. Science 303, 1532\u20131535 (2004).","journal-title":"Science"},{"key":"BFni2987_CR12","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1182\/blood-2010-06-290171","volume":"117","author":"KD Metzler","year":"2011","unstructured":"Metzler, K.D. et al. Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity. Blood 117, 953\u2013959 (2011).","journal-title":"Blood"},{"key":"BFni2987_CR13","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1083\/jcb.200606027","volume":"176","author":"TA Fuchs","year":"2007","unstructured":"Fuchs, T.A. et al. Novel cell death program leads to neutrophil extracellular traps. J. Cell Biol. 176, 231\u2013241 (2007).","journal-title":"J. Cell Biol."},{"key":"BFni2987_CR14","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1083\/jcb.201006052","volume":"191","author":"V Papayannopoulos","year":"2010","unstructured":"Papayannopoulos, V., Metzler, K.D., Hakkim, A. & Zychlinsky, A. Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps. J. Cell Biol. 191, 677\u2013691 (2010).","journal-title":"J. Cell Biol."},{"key":"BFni2987_CR15","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.celrep.2014.06.044","volume":"8","author":"KD Metzler","year":"2014","unstructured":"Metzler, K.D., Goosmann, C., Lubojemska, A., Zychlinsky, A. & Papayannopoulos, V. A myeloperoxidase-containing complex regulates neutrophil elastase release and actin dynamics during NETosis. Cell Reports 8, 883\u2013896 (2014).","journal-title":"Cell Reports"},{"key":"BFni2987_CR16","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1182\/blood-2009-05-221606","volume":"114","author":"M Bianchi","year":"2009","unstructured":"Bianchi, M. et al. Restoration of NET formation by gene therapy in CGD controls aspergillosis. Blood 114, 2619\u20132622 (2009).","journal-title":"Blood"},{"key":"BFni2987_CR17","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1172\/JCI106114","volume":"48","author":"RI Lehrer","year":"1969","unstructured":"Lehrer, R.I. & Cline, M.J. Leukocyte myeloperoxidase deficiency and disseminated candidiasis - role of myeloperoxidase in resistance to Candida infection. J. Clin. Invest. 48, 1478\u20131488 (1969).","journal-title":"J. Clin. Invest."},{"key":"BFni2987_CR18","doi-asserted-by":"crossref","first-page":"293","DOI":"10.7326\/0003-4819-95-3-293","volume":"95","author":"MF Parry","year":"1981","unstructured":"Parry, M.F. et al. Myeloperoxidase deficiency - prevalence and clinical significance. Ann. Intern. Med. 95, 293\u2013301 (1981).","journal-title":"Ann. Intern. Med."},{"key":"BFni2987_CR19","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s00281-013-0384-6","volume":"35","author":"N Branzk","year":"2013","unstructured":"Branzk, N. & Papayannopoulos, V. Molecular mechanisms regulating NETosis in infection and disease. Semin. Immunopathol. 35, 513\u2013530 (2013).","journal-title":"Semin. Immunopathol."},{"key":"BFni2987_CR20","doi-asserted-by":"crossref","first-page":"330","DOI":"10.3109\/08830185.2013.863305","volume":"33","author":"T Caza","year":"2014","unstructured":"Caza, T., Oaks, Z. & Perl, A. Interplay of infections, autoimmunity, and immunosuppression in systemic lupus erythematosus. Int. Rev. Immunol. 33, 330\u2013363 (2014).","journal-title":"Int. Rev. Immunol."},{"key":"BFni2987_CR21","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1038\/sj.emboj.7600195","volume":"23","author":"X Zheng","year":"2004","unstructured":"Zheng, X., Wang, Y. & Wang, Y. Hgc1, a novel hypha-specific G1 cyclin-related protein regulates Candida albicans hyphal morphogenesis. EMBO J. 23, 1845\u20131856 (2004).","journal-title":"EMBO J."},{"key":"BFni2987_CR22","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1002\/pmic.200700594","volume":"9","author":"M Mart\u00ednez-Gomariz","year":"2009","unstructured":"Mart\u00ednez-Gomariz, M. et al. Proteomic analysis of cytoplasmic and surface proteins from yeast cells, hyphae, and biofilms of Candida albicans. Proteomics 9, 2230\u20132252 (2009).","journal-title":"Proteomics"},{"key":"BFni2987_CR23","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1091\/mbc.e03-03-0179","volume":"15","author":"M Martchenko","year":"2004","unstructured":"Martchenko, M., Alarco, A.M., Harcus, D. & Whiteway, M. Superoxide dismutases in Candida albicans: transcriptional regulation and functional characterization of the hyphal-induced SOD5 gene. Mol. Biol. Cell 15, 456\u2013467 (2004).","journal-title":"Mol. Biol. Cell"},{"key":"BFni2987_CR24","doi-asserted-by":"crossref","first-page":"2802","DOI":"10.1128\/IAI.00051-08","volume":"76","author":"N Grinberg","year":"2008","unstructured":"Grinberg, N., Elazar, S., Rosenshine, I. & Shpigel, N.Y. \u03b2-hydroxybutyrate abrogates formation of bovine neutrophil extracellular traps and bactericidal activity against mammary pathogenic Escherichia coli. Infect. Immun. 76, 2802\u20132807 (2008).","journal-title":"Infect. Immun."},{"key":"BFni2987_CR25","doi-asserted-by":"crossref","first-page":"10472","DOI":"10.1074\/jbc.M111.280321","volume":"287","author":"Y Mori","year":"2012","unstructured":"Mori, Y. et al. \u03b1-Enolase of Streptococcus pneumoniae induces formation of neutrophil extracellular traps. J. Biol. Chem. 287, 10472\u201310481 (2012).","journal-title":"J. Biol. Chem."},{"key":"BFni2987_CR26","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1128\/IAI.00491-13","volume":"81","author":"M Domenech","year":"2013","unstructured":"Domenech, M., Ramos-Sevillano, E., Garcia, E., Moscoso, M. & Yuste, J. Biofilm formation avoids complement immunity and phagocytosis of Streptococcus pneumoniae. Infect. Immun. 81, 2606\u20132615 (2013).","journal-title":"Infect. Immun."},{"key":"BFni2987_CR27","doi-asserted-by":"crossref","first-page":"e1003819","DOI":"10.1371\/journal.ppat.1003819","volume":"9","author":"JN Walker","year":"2013","unstructured":"Walker, J.N. et al. The Staphylococcus aureus ArlRS two-component system is a novel regulator of agglutination and pathogenesis. PLoS Pathog. 9, e1003819 (2013).","journal-title":"PLoS Pathog."},{"key":"BFni2987_CR28","doi-asserted-by":"crossref","first-page":"e1002307","DOI":"10.1371\/journal.ppat.1002307","volume":"7","author":"M McAdow","year":"2011","unstructured":"McAdow, M. et al. Preventing Staphylococcus aureus sepsis through the inhibition of its agglutination in blood. PLoS Pathog. 7, e1002307 (2011).","journal-title":"PLoS Pathog."},{"key":"BFni2987_CR29","doi-asserted-by":"crossref","first-page":"E943","DOI":"10.1073\/pnas.1321390111","volume":"111","author":"A Bernut","year":"2014","unstructured":"Bernut, A. et al. Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation. Proc. Natl. Acad. Sci. USA 111, E943\u2013E952 (2014).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFni2987_CR30","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/nchembio.496","volume":"7","author":"A Hakkim","year":"2011","unstructured":"Hakkim, A. et al. Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation. Nat. Chem. Biol. 7, 75\u201377 (2011).","journal-title":"Nat. Chem. Biol."},{"key":"BFni2987_CR31","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/eji.201041252","volume":"41","author":"RA Drummond","year":"2011","unstructured":"Drummond, R.A., Saijo, S., Iwakura, Y. & Brown, G.D. The role of Syk\/CARD9 coupled C-type lectins in antifungal immunity. Eur. J. Immunol. 41, 276\u2013281 (2011).","journal-title":"Eur. J. Immunol."},{"key":"BFni2987_CR32","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1189\/jlb.0810457","volume":"90","author":"P Nordenfelt","year":"2011","unstructured":"Nordenfelt, P. & Tapper, H. Phagosome dynamics during phagocytosis by neutrophils. J. Leukoc. Biol. 90, 271\u2013284 (2011).","journal-title":"J. Leukoc. Biol."},{"key":"BFni2987_CR33","doi-asserted-by":"crossref","first-page":"2831","DOI":"10.4049\/jimmunol.177.5.2831","volume":"177","author":"F Mollinedo","year":"2006","unstructured":"Mollinedo, F. et al. Combinatorial SNARE complexes modulate the secretion of cytoplasmic granules in human neutrophils. J. Immunol. 177, 2831\u20132841 (2006).","journal-title":"J. Immunol."},{"key":"BFni2987_CR34","doi-asserted-by":"crossref","first-page":"4038","DOI":"10.1182\/blood-2004-03-1140","volume":"104","author":"J Herre","year":"2004","unstructured":"Herre, J. et al. Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages. Blood 104, 4038\u20134045 (2004).","journal-title":"Blood"},{"key":"BFni2987_CR35","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/eji.200636653","volume":"37","author":"AD Kennedy","year":"2007","unstructured":"Kennedy, A.D. et al. Dectin-1 promotes fungicidal activity of human neutrophils. Eur. J. Immunol. 37, 467\u2013478 (2007).","journal-title":"Eur. J. Immunol."},{"key":"BFni2987_CR36","doi-asserted-by":"crossref","first-page":"3986","DOI":"10.4049\/jimmunol.156.10.3986","volume":"156","author":"RW Watson","year":"1996","unstructured":"Watson, R.W., Redmond, H.P., Wang, J.H., Condron, C. & Bouchier-Hayes, D. Neutrophils undergo apoptosis following ingestion of Escherichia coli. J. Immunol. 156, 3986\u20133992 (1996).","journal-title":"J. Immunol."},{"key":"BFni2987_CR37","first-page":"73ra20","volume":"3","author":"GS Garcia-Romo","year":"2011","unstructured":"Garcia-Romo, G.S. et al. Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Sci. Transl. Med. 3, 73ra20 (2011).","journal-title":"Sci. Transl. Med."},{"key":"BFni2987_CR38","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/ar4325","volume":"15","author":"MJ Kaplan","year":"2013","unstructured":"Kaplan, M.J. Role of neutrophils in systemic autoimmune diseases. Arthritis Res. Ther. 15, 219 (2013).","journal-title":"Arthritis Res. Ther."},{"key":"BFni2987_CR39","doi-asserted-by":"crossref","first-page":"538","DOI":"10.4049\/jimmunol.1100450","volume":"187","author":"E Villanueva","year":"2011","unstructured":"Villanueva, E. et al. Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus. J. Immunol. 187, 538\u2013552 (2011).","journal-title":"J. Immunol."},{"key":"BFni2987_CR40","doi-asserted-by":"crossref","first-page":"3193","DOI":"10.1016\/j.febslet.2010.06.006","volume":"584","author":"AK Gupta","year":"2010","unstructured":"Gupta, A.K. et al. Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death. FEBS Lett. 584, 3193\u20133197 (2010).","journal-title":"FEBS Lett."},{"key":"BFni2987_CR41","doi-asserted-by":"publisher","unstructured":"Carmona-Rivera, C., Zhao, W., Yalavarthi, S. & Kaplan, M.J. Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2. Ann. Rheum. Dis. doi: 10.1136\/annrheumdis-2013-204837 (25 February 2014)10.1136\/annrheumdis-2013-204837.","DOI":"10.1136\/annrheumdis-2013-204837"},{"key":"BFni2987_CR42","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/ni1408","volume":"8","author":"PR Taylor","year":"2007","unstructured":"Taylor, P.R. et al. Dectin-1 is required for \u03b2-glucan recognition and control of fungal infection. Nat. Immunol. 8, 31\u201338 (2007).","journal-title":"Nat. Immunol."},{"key":"BFni2987_CR43","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1084\/jem.20082818","volume":"206","author":"MJ Robinson","year":"2009","unstructured":"Robinson, M.J. et al. Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection. J. Exp. Med. 206, 2037\u20132051 (2009).","journal-title":"J. Exp. Med."},{"key":"BFni2987_CR44","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0014-2999(99)00268-X","volume":"374","author":"K Fujie","year":"1999","unstructured":"Fujie, K. et al. Release of neutrophil elastase and its role in tissue injury in acute inflammation: effect of the elastase inhibitor, FR134043. Eur. J. Pharmacol. 374, 117\u2013125 (1999).","journal-title":"Eur. J. Pharmacol."},{"key":"BFni2987_CR45","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.2353\/ajpath.2010.090793","volume":"177","author":"T Ishii","year":"2010","unstructured":"Ishii, T. et al. Neutrophil elastase contributes to acute lung injury induced by bilateral nephrectomy. Am. J. Pathol. 177, 1665\u20131673 (2010).","journal-title":"Am. J. Pathol."},{"key":"BFni2987_CR46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0014-2999(02)02182-9","volume":"451","author":"K Kawabata","year":"2002","unstructured":"Kawabata, K., Hagio, T. & Matsuoka, S. The role of neutrophil elastase in acute lung injury. Eur. J. Pharmacol. 451, 1\u201310 (2002).","journal-title":"Eur. J. Pharmacol."},{"key":"BFni2987_CR47","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1083\/jcb.201304095","volume":"203","author":"A Prashar","year":"2013","unstructured":"Prashar, A. et al. Filamentous morphology of bacteria delays the timing of phagosome morphogenesis in macrophages. J. Cell Biol. 203, 1081\u20131097 (2013).","journal-title":"J. Cell Biol."},{"key":"BFni2987_CR48","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.clim.2004.07.016","volume":"114","author":"DJ Kusner","year":"2005","unstructured":"Kusner, D.J. Mechanisms of mycobacterial persistence in tuberculosis. Clin. Immunol. 114, 239\u2013247 (2005).","journal-title":"Clin. Immunol."},{"key":"BFni2987_CR49","doi-asserted-by":"crossref","first-page":"517","DOI":"10.2217\/17460913.3.5.517","volume":"3","author":"V Deretic","year":"2008","unstructured":"Deretic, V. Autophagy, an immunologic magic bullet: Mycobacterium tuberculosis phagosome maturation block and how to bypass it. Future Microbiol. 3, 517\u2013524 (2008).","journal-title":"Future Microbiol."},{"key":"BFni2987_CR50","doi-asserted-by":"crossref","first-page":"e1002507","DOI":"10.1371\/journal.ppat.1002507","volume":"8","author":"R Simeone","year":"2012","unstructured":"Simeone, R. et al. Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death. PLoS Pathog. 8, e1002507 (2012).","journal-title":"PLoS Pathog."},{"key":"BFni2987_CR51","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/infdis\/jit097","volume":"208","author":"KW Wong","year":"2013","unstructured":"Wong, K.W. & Jacobs, W.R. Jr. Mycobacterium tuberculosis exploits human interferon \u03b3 to stimulate macrophage extracellular trap formation and necrosis. J. Infect. Dis. 208, 109\u2013119 (2013).","journal-title":"J. Infect. Dis"},{"key":"BFni2987_CR52","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.chom.2012.05.015","volume":"12","author":"T Saitoh","year":"2012","unstructured":"Saitoh, T. et al. Neutrophil extracellular traps mediate a host defense response to human immunodeficiency virus-1. Cell Host Microbe 12, 109\u2013116 (2012).","journal-title":"Cell Host Microbe"},{"key":"BFni2987_CR53","doi-asserted-by":"crossref","first-page":"e57082","DOI":"10.1371\/journal.pone.0057082","volume":"8","author":"L Fossati-Jimack","year":"2013","unstructured":"Fossati-Jimack, L. et al. Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells. PLoS ONE 8, e57082 (2013).","journal-title":"PLoS ONE"},{"key":"BFni2987_CR54","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1007\/s10875-012-9821-x","volume":"33","author":"C Salazar-Aldrete","year":"2013","unstructured":"Salazar-Aldrete, C. et al. Expression and function of dectin-1 is defective in monocytes from patients with systemic lupus erythematosus and rheumatoid arthritis. J. Clin. Immunol. 33, 368\u2013377 (2013).","journal-title":"J. Clin. Immunol."},{"key":"BFni2987_CR55","doi-asserted-by":"crossref","first-page":"898","DOI":"10.4049\/jimmunol.169.2.898","volume":"169","author":"E Aga","year":"2002","unstructured":"Aga, E. et al. Inhibition of the spontaneous apoptosis of neutrophil granulocytes by the intracellular parasite Leishmania major. J. Immunol. 169, 898\u2013905 (2002).","journal-title":"J. Immunol."},{"key":"BFni2987_CR56","doi-asserted-by":"crossref","first-page":"20485","DOI":"10.1073\/pnas.1206811109","volume":"109","author":"B Kasmapour","year":"2012","unstructured":"Kasmapour, B., Gronow, A., Bleck, C.K., Hong, W. & Gutierrez, M.G. Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34. Proc. Natl. Acad. Sci. USA 109, 20485\u201320490 (2012).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFni2987_CR57","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1111\/j.1462-5822.2006.00877.x","volume":"9","author":"M Benghezal","year":"2007","unstructured":"Benghezal, M. et al. Inhibitors of bacterial virulence identified in a surrogate host model. Cell. Microbiol. 9, 1336\u20131342 (2007).","journal-title":"Cell. Microbiol."}],"container-title":["Nature Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ni.2987.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ni.2987","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ni.2987.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,16]],"date-time":"2023-07-16T10:50:58Z","timestamp":1689504658000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ni.2987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,14]]},"references-count":57,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["BFni2987"],"URL":"https:\/\/doi.org\/10.1038\/ni.2987","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718874876.793501354","asserted-by":"object"}]},"ISSN":["1529-2908","1529-2916"],"issn-type":[{"value":"1529-2908","type":"print"},{"value":"1529-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,14]]},"assertion":[{"value":"1 July 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 August 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 September 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}