{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:50:45Z","timestamp":1790859045210,"version":"4.1.0"},"reference-count":110,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2003,6,1]],"date-time":"2003-06-01T00:00:00Z","timestamp":1054425600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Immunol"],"published-print":{"date-parts":[[2003,6]]},"DOI":"10.1038\/ni0603-517","type":"journal-article","created":{"date-parts":[[2003,5,28]],"date-time":"2003-05-28T21:51:07Z","timestamp":1054158667000},"page":"517-523","source":"Crossref","is-referenced-by-count":90,"title":["Understanding the function of CD1-restricted T cells"],"prefix":"10.1038","volume":"4","author":[{"given":"Michael S","family":"Vincent","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny E","family":"Gumperz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B","family":"Brenner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BFni0603517_CR1","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1126\/science.277.5324.339","volume":"277","author":"Z Zeng","year":"1997","unstructured":"Zeng, Z. et al. Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove. Science 277, 339\u2013345 (1997).","journal-title":"Science"},{"key":"BFni0603517_CR2","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1038\/ni821","volume":"3","author":"SD Gadola","year":"2002","unstructured":"Gadola, S.D. et al. Structure of human CD1b with bound ligands at 2.3 \u00c5, a maze for alkyl chains. Nat. Immunol. 3, 721\u2013726 (2002).","journal-title":"Nat. Immunol."},{"key":"BFni0603517_CR3","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1002\/eji.1830190211","volume":"19","author":"F Calabi","year":"1989","unstructured":"Calabi, F., Jarvis, J.M., Martin, L. & Milstein, C. Two classes of CD1 genes. Eur. J. Immunol. 19, 285\u2013292 (1989).","journal-title":"Eur. J. Immunol."},{"key":"BFni0603517_CR4","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.4049\/jimmunol.147.8.2518","volume":"147","author":"RS Blumberg","year":"1991","unstructured":"Blumberg, R.S. et al. Expression of a nonpolymorphic MHC class I-like molecule, CD1D, by human intestinal epithelial cells. J. Immunol. 147, 2518\u20132524 (1991).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR5","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.4049\/jimmunol.159.3.1216","volume":"159","author":"L Brossay","year":"1997","unstructured":"Brossay, L. et al. Mouse CD1 is mainly expressed on hemopoietic-derived cells. J. Immunol. 159, 1216\u20131224 (1997).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR6","doi-asserted-by":"publisher","first-page":"3468","DOI":"10.1002\/1521-4141(2000012)30:12<3468::AID-IMMU3468>3.0.CO;2-C","volume":"30","author":"FM Spada","year":"2000","unstructured":"Spada, F.M. et al. Low expression level but potent antigen presenting function of CD1d on monocyte lineage cells. Eur. J. Immunol. 30, 3468\u20133477 (2000).","journal-title":"Eur. J. Immunol."},{"key":"BFni0603517_CR7","doi-asserted-by":"publisher","first-page":"9154","DOI":"10.1073\/pnas.83.23.9154","volume":"83","author":"LH Martin","year":"1986","unstructured":"Martin, L.H., Calabi, F. & Milstein, C. Isolation of CD1 genes: a family of major histocompatibility complex\u2013related differentiation antigens. Proc. Natl. Acad. Sci. USA 83, 9154\u20139158 (1986).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFni0603517_CR8","doi-asserted-by":"crossref","first-page":"768","DOI":"10.4049\/jimmunol.146.2.768","volume":"146","author":"SP Balk","year":"1991","unstructured":"Balk, S.P., Bleicher, P.A. & Terhorst, C. Isolation and expression of cDNA encoding the murine homologues of CD1. J. Immunol. 146, 768\u2013774 (1991).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR9","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.4049\/jimmunol.159.5.2358","volume":"159","author":"M Sugita","year":"1997","unstructured":"Sugita, M., Porcelli, S.A. & Brenner, M.B. Assembly and retention of CD1b heavy chains in the endoplasmic reticulum. J. Immunol. 159, 2358\u20132365 (1997).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR10","doi-asserted-by":"publisher","first-page":"44838","DOI":"10.1074\/jbc.M207831200","volume":"277","author":"SJ Kang","year":"2002","unstructured":"Kang, S.J. & Cresswell, P. Calnexin, calreticulin, and ERp57 cooperate in disulfide bond formation in human CD1d heavy chain. J. Biol. Chem. 277, 44838\u201344844 (2002).","journal-title":"J. Biol. Chem."},{"key":"BFni0603517_CR11","doi-asserted-by":"publisher","first-page":"1541","DOI":"10.1126\/science.279.5356.1541","volume":"279","author":"S Joyce","year":"1998","unstructured":"Joyce, S. et al. Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol. Science 279, 1541\u20131544 (1998).","journal-title":"Science"},{"key":"BFni0603517_CR12","doi-asserted-by":"publisher","first-page":"723","DOI":"10.4049\/jimmunol.168.2.723","volume":"168","author":"AD De Silva","year":"2002","unstructured":"De Silva, A.D. et al. Lipid protein interactions: the assembly of CD1d1 with cellular phospholipids occurs in the endoplasmic reticulum. J. Immunol. 168, 723\u2013733 (2002).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR13","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1016\/S1074-7613(00)80148-X","volume":"11","author":"M Sugita","year":"1999","unstructured":"Sugita, M. et al. Separate pathways for antigen presentation by CD1 molecules. Immunity 11, 743\u2013752 (1999).","journal-title":"Immunity"},{"key":"BFni0603517_CR14","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1093\/emboj\/21.4.825","volume":"21","author":"V Briken","year":"2002","unstructured":"Briken, V., Jackman, R.M., Dasgupta, S., Hoening, S. & Porcelli, S.A. Intracellular trafficking pathway of newly synthesized CD1b molecules. EMBO J. 21, 825\u2013834 (2002).","journal-title":"EMBO J."},{"key":"BFni0603517_CR15","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/S1074-7613(00)80539-7","volume":"8","author":"RM Jackman","year":"1998","unstructured":"Jackman, R.M. et al. The tyrosine-containing cytoplasmic tail of CD1b is essential for its efficient presentation of bacterial lipid antigens. Immunity 8, 341\u2013351 (1998).","journal-title":"Immunity"},{"key":"BFni0603517_CR16","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1016\/S1074-7613(02)00311-4","volume":"16","author":"M Sugita","year":"2002","unstructured":"Sugita, M. et al. Failure of trafficking and antigen presentation by CD1 in AP-3\u2013deficient cells. Immunity 16, 697\u2013706 (2002).","journal-title":"Immunity"},{"key":"BFni0603517_CR17","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1084\/jem.189.1.103","volume":"189","author":"YH Chiu","year":"1999","unstructured":"Chiu, Y.H. et al. Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments. J. Exp. Med. 189, 103\u2013110 (1999).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR18","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1038\/372691a0","volume":"372","author":"EM Beckman","year":"1994","unstructured":"Beckman, E.M. et al. Recognition of a lipid antigen by CD1-restricted \u03b1\u03b2+ T cells. Nature 372, 691\u2013694 (1994).","journal-title":"Nature"},{"key":"BFni0603517_CR19","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1126\/science.7542404","volume":"269","author":"PA Sieling","year":"1995","unstructured":"Sieling, P.A. et al. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science 269, 227\u2013230 (1995).","journal-title":"Science"},{"key":"BFni0603517_CR20","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1126\/science.278.5336.283","volume":"278","author":"DB Moody","year":"1997","unstructured":"Moody, D.B. et al. Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells. Science 278, 283\u2013286 (1997).","journal-title":"Science"},{"key":"BFni0603517_CR21","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1038\/35009119","volume":"404","author":"DB Moody","year":"2000","unstructured":"Moody, D.B. et al. CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. Nature 404, 884\u2013888 (2000).","journal-title":"Nature"},{"key":"BFni0603517_CR22","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1084\/jem.189.1.195","volume":"189","author":"EP Grant","year":"1999","unstructured":"Grant, E.P. et al. Molecular recognition of lipid antigens by T cell receptors. J. Exp. Med. 189, 195\u2013205 (1999).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR23","doi-asserted-by":"publisher","first-page":"3933","DOI":"10.4049\/jimmunol.168.8.3933","volume":"168","author":"EP Grant","year":"2002","unstructured":"Grant, E.P. et al. Fine specificity of TCR complementarity-determining region residues and lipid antigen hydrophilic moieties in the recognition of a CD1-lipid complex. J. Immunol. 168, 3933\u20133940 (2002).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR24","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1038\/341447a0","volume":"341","author":"S Porcelli","year":"1989","unstructured":"Porcelli, S. et al. Recognition of cluster of differentiation 1 antigens by human CD4\u2212CD8\u2212 cytolytic T lymphocytes. Nature 341, 447\u2013450 (1989).","journal-title":"Nature"},{"key":"BFni0603517_CR25","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1126\/science.7538697","volume":"268","author":"A Bendelac","year":"1995","unstructured":"Bendelac, A. et al. CD1 recognition by mouse NK1+ T lymphocytes. Science 268, 863\u2013865 (1995).","journal-title":"Science"},{"key":"BFni0603517_CR26","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1084\/jem.186.1.109","volume":"186","author":"M Exley","year":"1997","unstructured":"Exley, M., Garcia, J., Balk, S.P. & Porcelli, S. Requirements for CD1d recognition by human invariant V\u03b124+CD4\u2212CD8\u2212 T cells. J. Exp. Med. 186, 109\u2013120 (1997).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR27","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1182\/blood.V95.7.2440","volume":"95","author":"HJ van Der Vliet","year":"2000","unstructured":"van Der Vliet, H.J. et al. Human natural killer T cells acquire a memory-activated phenotype before birth. Blood 95, 2440\u20132442 (2000).","journal-title":"Blood"},{"key":"BFni0603517_CR28","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1002\/1521-4141(200002)30:2<620::AID-IMMU620>3.0.CO;2-4","volume":"30","author":"SH Park","year":"2000","unstructured":"Park, S.H., Benlagha, K., Lee, D., Balish, E. & Bendelac, A. Unaltered phenotype, tissue distribution and function of V\u03b114+ NKT cells in germ-free mice. Eur. J. Immunol. 30, 620\u2013625 (2000).","journal-title":"Eur. J. Immunol."},{"key":"BFni0603517_CR29","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/S1074-7613(00)80092-8","volume":"11","author":"B Ernst","year":"1999","unstructured":"Ernst, B., Lee, D.S., Chang, J.M., Sprent, J. & Surh, C.D. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 11, 173\u2013181 (1999).","journal-title":"Immunity"},{"key":"BFni0603517_CR30","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/S1074-7613(00)80317-9","volume":"5","author":"S Takeda","year":"1996","unstructured":"Takeda, S., Rodewald, H.R., Arakawa, H., Bluethmann, H. & Shimizu, T. MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span. Immunity 5, 217\u2013228 (1996).","journal-title":"Immunity"},{"key":"BFni0603517_CR31","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1038\/nature01146","volume":"420","author":"I Stefanova","year":"2002","unstructured":"Stefanova, I., Dorfman, J.R. & Germain, R.N. Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes. Nature 420, 429\u2013434 (2002).","journal-title":"Nature"},{"key":"BFni0603517_CR32","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1084\/jem.191.6.937","volume":"191","author":"FM Spada","year":"2000","unstructured":"Spada, F.M. et al. Self-recognition of CD1 by \u03b3\/\u03b4 T cells: implications for innate immunity. J. Exp. Med. 191, 937\u2013948 (2000).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR33","doi-asserted-by":"publisher","first-page":"1667","DOI":"10.1002\/(SICI)1521-4141(199905)29:05<1667::AID-IMMU1667>3.0.CO;2-U","volume":"29","author":"A Shamshiev","year":"1999","unstructured":"Shamshiev, A. et al. Self glycolipids as T-cell autoantigens. Eur. J. Immunol. 29, 1667\u20131675 (1999).","journal-title":"Eur. J. Immunol."},{"key":"BFni0603517_CR34","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1084\/jem.20011963","volume":"195","author":"A Shamshiev","year":"2002","unstructured":"Shamshiev, A. et al. Presentation of the same glycolipid by different CD1 molecules. J. Exp. Med. 195, 1013\u20131021 (2002).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR35","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S1074-7613(00)80174-0","volume":"12","author":"JE Gumperz","year":"2000","unstructured":"Gumperz, J.E. et al. Murine CD1d-restricted T cell recognition of cellular lipids. Immunity 12, 211\u2013221 (2000).","journal-title":"Immunity"},{"key":"BFni0603517_CR36","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1084\/jem.180.3.1097","volume":"180","author":"O Lantz","year":"1994","unstructured":"Lantz, O. & Bendelac, A. An invariant T cell receptor \u03b1 chain is used by a unique subset of major histocompatibility complex class I\u2013specific CD4+ and CD4\u22128\u2212 T cells in mice and humans. J. Exp. Med. 180, 1097\u20131106 (1994).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR37","doi-asserted-by":"publisher","first-page":"1755","DOI":"10.4049\/jimmunol.166.3.1755","volume":"166","author":"C Ronet","year":"2001","unstructured":"Ronet, C. et al. Role of the complementarity-determining region 3 (CDR3) of the TCR \u03b2-chains associated with the V\u03b114 semi-invariant TCR \u03b1-chain in the selection of CD4+ NK T Cells. J. Immunol. 166, 1755\u20131762 (2001).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR38","doi-asserted-by":"publisher","first-page":"12636","DOI":"10.1073\/pnas.221445298","volume":"98","author":"JL Matsuda","year":"2001","unstructured":"Matsuda, J.L. et al. Natural killer T cells reactive to a single glycolipid exhibit a highly diverse T cell receptor \u03b2 repertoire and small clone size. Proc. Natl. Acad. Sci. USA 98, 12636\u201312641 (2001).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFni0603517_CR39","doi-asserted-by":"crossref","first-page":"3229","DOI":"10.4049\/jimmunol.147.9.3229","volume":"147","author":"WM Yokoyama","year":"1991","unstructured":"Yokoyama, W.M. et al. cDNA cloning of mouse NKR-P1 and genetic linkage with LY-49. Identification of a natural killer cell gene complex on mouse chromosome 6. J. Immunol. 147, 3229\u20133236 (1991).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR40","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1084\/jem.193.8.893","volume":"193","author":"SH Park","year":"2001","unstructured":"Park, S.H. et al. The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families. J. Exp. Med. 193, 893\u2013904 (2001).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR41","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1084\/jem.182.4.993","volume":"182","author":"S Cardell","year":"1995","unstructured":"Cardell, S. et al. CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice. J. Exp. Med. 182, 993\u20131004 (1995).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR42","doi-asserted-by":"publisher","first-page":"5531","DOI":"10.4049\/jimmunol.167.10.5531","volume":"167","author":"MA Exley","year":"2001","unstructured":"Exley, M.A. et al. A major fraction of human bone marrow lymphocytes are Th2-like CD1d-reactive T cells that can suppress mixed lymphocyte responses. J. Immunol. 167, 5531\u20135534 (2001).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR43","doi-asserted-by":"publisher","first-page":"1626","DOI":"10.1126\/science.278.5343.1626","volume":"278","author":"T Kawano","year":"1997","unstructured":"Kawano, T. et al. CD1d-restricted and TCR-mediated activation of V\u03b114 NKT cells by glycosylceramides. Science 278, 1626\u20131629 (1997).","journal-title":"Science"},{"key":"BFni0603517_CR44","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1084\/jem.192.5.741","volume":"192","author":"JL Matsuda","year":"2000","unstructured":"Matsuda, J.L. et al. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J. Exp. Med. 192, 741\u2013754 (2000).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR45","doi-asserted-by":"publisher","first-page":"1895","DOI":"10.1084\/jem.191.11.1895","volume":"191","author":"K Benlagha","year":"2000","unstructured":"Benlagha, K., Weiss, A., Beavis, A., Teyton, L. & Bendelac, A. In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers. J. Exp. Med. 191, 1895\u20131903 (2000).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR46","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1084\/jem.20011786","volume":"195","author":"JE Gumperz","year":"2002","unstructured":"Gumperz, J.E., Miyake, S., Yamamura, T. & Brenner, M.B. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J. Exp. Med. 195, 625\u2013636 (2002).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR47","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1084\/jem.20011908","volume":"195","author":"PT Lee","year":"2002","unstructured":"Lee, P.T., Benlagha, K., Teyton, L. & Bendelac, A. Distinct functional lineages of human V\u03b124 natural killer T cells. J. Exp. Med. 195, 637\u2013641 (2002).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR48","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1038\/360593a0","volume":"360","author":"S Porcelli","year":"1992","unstructured":"Porcelli, S., Morita, C.T. & Brenner, M.B. CD1b restricts the response of human CD4\u22128\u2212 T lymphocytes to a microbial antigen. Nature 360, 593\u2013597 (1992).","journal-title":"Nature"},{"key":"BFni0603517_CR49","doi-asserted-by":"crossref","first-page":"366","DOI":"10.4049\/jimmunol.162.1.366","volume":"162","author":"JP Rosat","year":"1999","unstructured":"Rosat, J.P. et al. CD1-restricted microbial lipid antigen-specific recognition found in the CD8+ \u03b1\u03b2 T cell pool. J. Immunol. 162, 366\u2013371 (1999).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR50","doi-asserted-by":"publisher","first-page":"4790","DOI":"10.4049\/jimmunol.164.9.4790","volume":"164","author":"PA Sieling","year":"2000","unstructured":"Sieling, P.A. et al. Evidence for human CD4+ T cells in the CD1-restricted repertoire: derivation of mycobacteria-reactive T cells from leprosy lesions. J. Immunol. 164, 4790\u20134796 (2000).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR51","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1038\/ni851","volume":"3","author":"MS Vincent","year":"2002","unstructured":"Vincent, M.S. et al. CD1-dependent dendritic cell instruction. Nat. Immunol. 3, 1163\u20131168 (2002).","journal-title":"Nat. Immunol."},{"key":"BFni0603517_CR52","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1038\/42030","volume":"388","author":"M Cella","year":"1997","unstructured":"Cella, M., Engering, A., Pinet, V., Pieters, J. & Lanzavecchia, A. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 388, 782\u2013787 (1997).","journal-title":"Nature"},{"key":"BFni0603517_CR53","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1038\/42039","volume":"388","author":"P Pierre","year":"1997","unstructured":"Pierre, P. et al. Developmental regulation of MHC class II transport in mouse dendritic cells. Nature 388, 787\u2013792 (1997).","journal-title":"Nature"},{"key":"BFni0603517_CR54","doi-asserted-by":"publisher","first-page":"4770","DOI":"10.4049\/jimmunol.169.9.4770","volume":"169","author":"X Cao","year":"2002","unstructured":"Cao, X. et al. CD1 molecules efficiently present antigen in immature dendritic cells and traffic independently of MHC class II during dendritic cell maturation. J. Immunol. 169, 4770\u20134777 (2002).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR55","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/S1471-4906(02)02281-0","volume":"23","author":"MB Lutz","year":"2002","unstructured":"Lutz, M.B. & Schuler, G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 23, 445\u2013449 (2002).","journal-title":"Trends Immunol"},{"key":"BFni0603517_CR56","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1084\/jem.20021515","volume":"196","author":"DS Leslie","year":"2002","unstructured":"Leslie, D.S. et al. CD1-mediated \u03b3\/\u03b4 T cell maturation of dendritic cells. J. Exp. Med. 196, 1575\u20131584 (2002).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR57","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1084\/jem.189.7.1121","volume":"189","author":"H Kitamura","year":"1999","unstructured":"Kitamura, H. et al. The natural killer T (NKT) cell ligand \u03b1-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells. J. Exp. Med. 189, 1121\u20131128 (1999).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR58","doi-asserted-by":"crossref","first-page":"2795","DOI":"10.4049\/jimmunol.157.7.2795","volume":"157","author":"EM Beckman","year":"1996","unstructured":"Beckman, E.M. et al. CD1c restricts responses of mycobacteria-specific T cells. Evidence for antigen presentation by a second member of the human CD1 family. J. Immunol. 157, 2795\u20132803 (1996).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR59","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.1126\/science.276.5319.1684","volume":"276","author":"S Stenger","year":"1997","unstructured":"Stenger, S. et al. Differential effects of cytolytic T cell subsets on intracellular infection. Science 276, 1684\u20131687 (1997).","journal-title":"Science"},{"key":"BFni0603517_CR60","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1126\/science.282.5386.121","volume":"282","author":"S Stenger","year":"1998","unstructured":"Stenger, S. et al. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 282, 121\u2013125 (1998).","journal-title":"Science"},{"key":"BFni0603517_CR61","unstructured":"Kawashima, T. et al. Major CD8 T cell response to live BCG is mediated by CD1 molecules. J. Immunol. in the press"},{"key":"BFni0603517_CR62","doi-asserted-by":"crossref","first-page":"5478","DOI":"10.4049\/jimmunol.163.10.5478","volume":"163","author":"CC Dascher","year":"1999","unstructured":"Dascher, C.C. et al. Conservation of a CD1 multigene family in the guinea pig. J. Immunol. 163, 5478\u20135488 (1999).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR63","doi-asserted-by":"publisher","first-page":"330","DOI":"10.4049\/jimmunol.169.1.330","volume":"169","author":"K Hiromatsu","year":"2002","unstructured":"Hiromatsu, K. et al. Induction of CD1-restricted immune responses in guinea pigs by immunization with mycobacterial lipid antigens. J. Immunol. 169, 330\u2013339 (2002).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR64","doi-asserted-by":"crossref","unstructured":"Dascher, C.C. et al. Immunization with a mycobacterial lipid vaccine improves pulmonary pathology in the guinea pig model of tuberculosis. Int. Immunol. in the press.","DOI":"10.1093\/intimm\/dxg091"},{"key":"BFni0603517_CR65","doi-asserted-by":"crossref","first-page":"4647","DOI":"10.4049\/jimmunol.163.9.4647","volume":"163","author":"C Carnaud","year":"1999","unstructured":"Carnaud, C. et al. Cutting edge: cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells. J. Immunol. 163, 4647\u20134650 (1999).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR66","doi-asserted-by":"publisher","first-page":"8461","DOI":"10.1073\/pnas.97.15.8461","volume":"97","author":"G Gonzalez-Aseguinolaza","year":"2000","unstructured":"Gonzalez-Aseguinolaza, G. et al. \u03b1-Galactosylceramide-activated V\u03b114 natural killer T cells mediate protection against murine malaria. Proc. Natl. Acad. Sci. USA 97, 8461\u20138466 (2000).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFni0603517_CR67","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1128\/IAI.69.1.213-220.2001","volume":"69","author":"K Kawakami","year":"2001","unstructured":"Kawakami, K. et al. Activation of V\u03b114+ natural killer T cells by \u03b1-galactosylceramide results in development of Th1 response and local host resistance in mice infected with Cryptococcus neoformans. Infect. Immun. 69, 213\u2013220 (2001).","journal-title":"Infect. Immun."},{"key":"BFni0603517_CR68","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1189\/jlb.69.5.713","volume":"69","author":"MA Exley","year":"2001","unstructured":"Exley, M.A. et al. CD1d-reactive T-cell activation leads to amelioration of disease caused by diabetogenic encephalomyocarditis virus. J. Leukoc. Biol. 69, 713\u2013718 (2001).","journal-title":"J. Leukoc. Biol."},{"key":"BFni0603517_CR69","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1038\/nm0602-588","volume":"8","author":"EE Nieuwenhuis","year":"2002","unstructured":"Nieuwenhuis, E.E. et al. CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung. Nat. Med. 8, 588\u2013593 (2002).","journal-title":"Nat. Med."},{"key":"BFni0603517_CR70","doi-asserted-by":"publisher","first-page":"6302","DOI":"10.1128\/IAI.70.11.6302-6309.2002","volume":"70","author":"A Chackerian","year":"2002","unstructured":"Chackerian, A., Alt, J., Perera, V. & Behar, S.M. Activation of NKT cells protects mice from tuberculosis. Infect. Immun. 70, 6302\u20136309 (2002).","journal-title":"Infect. Immun."},{"key":"BFni0603517_CR71","doi-asserted-by":"publisher","first-page":"5778","DOI":"10.4049\/jimmunol.168.11.5778","volume":"168","author":"MS Duthie","year":"2002","unstructured":"Duthie, M.S. & Kahn, S.J. Treatment with \u03b1-galactosylceramide before Trypanosoma cruzi infection provides protection or induces failure to thrive. J. Immunol. 168, 5778\u20135785 (2002).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR72","doi-asserted-by":"publisher","first-page":"4294","DOI":"10.1128\/JVI.76.9.4294-4303.2002","volume":"76","author":"TR Johnson","year":"2002","unstructured":"Johnson, T.R., Hong, S., Van Kaer, L., Koezuka, Y. & Graham, B.S. NK T cells contribute to expansion of CD8+ T cells and amplification of antiviral immune responses to respiratory syncytial virus. J. Virol. 76, 4294\u20134303 (2002).","journal-title":"J. Virol."},{"key":"BFni0603517_CR73","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1126\/science.283.5399.225","volume":"283","author":"L Schofield","year":"1999","unstructured":"Schofield, L. et al. CD1d-restricted immunoglobulin G formation to GPI-anchored antigens mediated by NKT cells. Science 283, 225\u2013229 (1999).","journal-title":"Science"},{"key":"BFni0603517_CR74","doi-asserted-by":"publisher","first-page":"5005","DOI":"10.4049\/jimmunol.164.10.5005","volume":"164","author":"A Molano","year":"2000","unstructured":"Molano, A. et al. Cutting edge: the IgG response to the circumsporozoite protein is MHC class II-dependent and CD1d-independent: exploring the role of GPIs in NK T cell activation and antimalarial responses. J. Immunol. 164, 5005\u20135009 (2000).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR75","doi-asserted-by":"publisher","first-page":"3926","DOI":"10.4049\/jimmunol.169.7.3926","volume":"169","author":"DO Procopio","year":"2002","unstructured":"Procopio, D.O. et al. Glycosylphosphatidylinositol-anchored mucin-like glycoproteins from Trypanosoma cruzi bind to CD1d but do not elicit dominant innate or adaptive immune responses via the CD1d\/NKT cell pathway. J. Immunol. 169, 3926\u20133933 (2002).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR76","doi-asserted-by":"publisher","first-page":"5141","DOI":"10.1073\/pnas.96.9.5141","volume":"96","author":"I Apostolou","year":"1999","unstructured":"Apostolou, I. et al. Murine natural killer T (NKT) cells contribute to the granulomatous reaction caused by mycobacterial cell walls. Proc. Natl. Acad. Sci. USA 96, 5141\u20135146 (1999).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFni0603517_CR77","doi-asserted-by":"publisher","first-page":"365","DOI":"10.4049\/jimmunol.168.1.365","volume":"168","author":"M Mempel","year":"2002","unstructured":"Mempel, M. et al. Natural killer T cells restricted by the monomorphic MHC class 1b CD1d1 molecules behave like inflammatory cells. J. Immunol. 168, 365\u2013371 (2002).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR78","doi-asserted-by":"publisher","first-page":"4797","DOI":"10.4049\/jimmunol.165.9.4797","volume":"165","author":"H Kumar","year":"2000","unstructured":"Kumar, H., Belperron, A., Barthold, S.W. & Bockenstedt, L.K. Cutting edge: CD1d deficiency impairs murine host defense against the spirochete, Borrelia burgdorferi. J. Immunol. 165, 4797\u20134801 (2000).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR79","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1128\/IAI.70.1.36-48.2002","volume":"70","author":"MS Duthie","year":"2002","unstructured":"Duthie, M.S. et al. During Trypanosoma cruzi infection CD1d-restricted NK T cells limit parasitemia and augment the antibody response to a glycophosphoinositol-modified surface protein. Infect. Immun. 70, 36\u201348 (2002).","journal-title":"Infect. Immun."},{"key":"BFni0603517_CR80","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.1126\/science.278.5343.1623","volume":"278","author":"J Cui","year":"1997","unstructured":"Cui, J. et al. Requirement for V\u03b114 NKT cells in IL-12\u2013mediated rejection of tumors. Science 278, 1623\u20131626 (1997).","journal-title":"Science"},{"key":"BFni0603517_CR81","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.4049\/jimmunol.163.5.2387","volume":"163","author":"I Toura","year":"1999","unstructured":"Toura, I. et al. Cutting edge: inhibition of experimental tumor metastasis by dendritic cells pulsed with \u03b1-galactosylceramide. J. Immunol. 163, 2387\u20132391 (1999).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR82","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1038\/ni827","volume":"3","author":"S Fujii","year":"2002","unstructured":"Fujii, S., Shimizu, K., Kronenberg, M. & Steinman, R.M. Prolonged IFN-\u03b3\u2013producing NKT response induced with \u03b1-galactosylceramide-loaded DCs. Nat. Immunol. 3, 867\u2013874 (2002).","journal-title":"Nat. Immunol."},{"key":"BFni0603517_CR83","doi-asserted-by":"publisher","first-page":"10231","DOI":"10.1073\/pnas.172380699","volume":"99","author":"S Hakomori","year":"2002","unstructured":"Hakomori, S. Glycosylation defining cancer malignancy: new wine in an old bottle. Proc. Natl. Acad. Sci. USA 99, 10231\u201310233 (2002).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFni0603517_CR84","doi-asserted-by":"publisher","first-page":"5796","DOI":"10.4049\/jimmunol.169.10.5796","volume":"169","author":"S Ostrand-Rosenberg","year":"2002","unstructured":"Ostrand-Rosenberg, S. et al. Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhematopoietic cells and is IFN-\u03b3 dependent. J. Immunol. 169, 5796\u20135804 (2002).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR85","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1038\/82771","volume":"1","author":"M Terabe","year":"2000","unstructured":"Terabe, M. et al. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R\u2013STAT6 pathway. Nat. Immunol. 1, 515\u2013520 (2000).","journal-title":"Nat. Immunol."},{"key":"BFni0603517_CR86","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1084\/jem.191.4.661","volume":"191","author":"MJ Smyth","year":"2000","unstructured":"Smyth, M.J. et al. Differential tumor surveillance by natural killer (NK) and NKT cells. J. Exp. Med. 191, 661\u2013668 (2000).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR87","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1093\/intimm\/13.4.459","volume":"13","author":"MJ Smyth","year":"2001","unstructured":"Smyth, M.J., Crowe, N.Y. & Godfrey, D.I. NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma. Int. Immunol. 13, 459\u2013463 (2001).","journal-title":"Int. Immunol."},{"key":"BFni0603517_CR88","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1084\/jem.20020092","volume":"196","author":"NY Crowe","year":"2002","unstructured":"Crowe, N.Y., Smyth, M.J. & Godfrey, D.I. A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas. J. Exp. Med. 196, 119\u2013127 (2002).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR89","doi-asserted-by":"publisher","first-page":"2429","DOI":"10.1038\/sj.leu.2402711","volume":"16","author":"Z Zheng","year":"2002","unstructured":"Zheng, Z., Venkatapathy, S., Rao, G. & Harrington, C.A. Expression profiling of B cell chronic lymphocytic leukemia suggests deficient CD1-mediated immunity, polarized cytokine response, altered adhesion and increased intracellular protein transport and processing of leukemic cells. Leukemia 16, 2429\u20132437 (2002).","journal-title":"Leukemia"},{"key":"BFni0603517_CR90","doi-asserted-by":"publisher","first-page":"5338","DOI":"10.4049\/jimmunol.165.9.5338","volume":"165","author":"PA Sieling","year":"2000","unstructured":"Sieling, P.A. et al. Human double-negative T cells in systemic lupus erythematosus provide help for IgG and are restricted by CD1c. J. Immunol. 165, 5338\u20135344 (2000).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR91","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1038\/35097097","volume":"413","author":"K Miyamoto","year":"2001","unstructured":"Miyamoto, K., Miyake, S. & Yamamura, T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 413, 531\u2013534 (2001).","journal-title":"Nature"},{"key":"BFni0603517_CR92","doi-asserted-by":"publisher","first-page":"1801","DOI":"10.1084\/jem.194.12.1801","volume":"194","author":"AK Singh","year":"2001","unstructured":"Singh, A.K. et al. Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J. Exp. Med. 194, 1801\u20131811 (2001).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR93","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1084\/jem.194.12.1789","volume":"194","author":"AW Jahng","year":"2001","unstructured":"Jahng, A.W. et al. Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis. J. Exp. Med. 194, 1789\u20131799 (2001).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR94","doi-asserted-by":"publisher","first-page":"2989","DOI":"10.1002\/eji.1830261226","volume":"26","author":"JM Gombert","year":"1996","unstructured":"Gombert, J.M. et al. Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse. Eur. J. Immunol. 26, 2989\u20132998 (1996).","journal-title":"Eur. J. Immunol."},{"key":"BFni0603517_CR95","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1084\/jem.190.7.963","volume":"190","author":"M Falcone","year":"1999","unstructured":"Falcone, M., Yeung, B., Tucker, L., Rodriguez, E. & Sarvetnick, N. A defect in interleukin 12\u2013induced activation and interferon \u03b3 secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus. J. Exp. Med. 190, 963\u2013972 (1999).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR96","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.4049\/jimmunol.167.3.1164","volume":"167","author":"KJ Hammond","year":"2001","unstructured":"Hammond, K.J. et al. CD1d-restricted NKT cells: an interstrain comparison. J. Immunol. 167, 1164\u20131173 (2001).","journal-title":"J. Immunol."},{"key":"BFni0603517_CR97","doi-asserted-by":"publisher","first-page":"572","DOI":"10.2337\/diab.46.4.572","volume":"46","author":"AG Baxter","year":"1997","unstructured":"Baxter, A.G., Kinder, S.J., Hammond, K.J., Scollay, R. & Godfrey, D.I. Association between \u03b1\u03b2TCR+CD4\u2212CD8\u2212 T-cell deficiency and IDDM in NOD\/Lt mice. Diabetes 46, 572\u2013582 (1997).","journal-title":"Diabetes"},{"key":"BFni0603517_CR98","doi-asserted-by":"publisher","first-page":"1831","DOI":"10.1084\/jem.188.10.1831","volume":"188","author":"A Lehuen","year":"1998","unstructured":"Lehuen, A. et al. Overexpression of natural killer T cells protects V\u03b114-J\u03b1281 transgenic nonobese diabetic mice against diabetes. J. Exp. Med. 188, 1831\u20131839 (1998).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR99","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1038\/nm0901-1057","volume":"7","author":"S Sharif","year":"2001","unstructured":"Sharif, S. et al. Activation of natural killer T cells by \u03b1-galactosylceramide treatment prevents the onset and recurrence of autoimmune type 1 diabetes. Nat. Med. 7, 1057\u20131062 (2001).","journal-title":"Nat. Med."},{"key":"BFni0603517_CR100","doi-asserted-by":"publisher","first-page":"1052","DOI":"10.1038\/nm0901-1052","volume":"7","author":"S Hong","year":"2001","unstructured":"Hong, S. et al. The natural killer T-cell ligand \u03b1-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice. Nat. Med. 7, 1052\u20131056 (2001).","journal-title":"Nat. Med."},{"key":"BFni0603517_CR101","doi-asserted-by":"publisher","first-page":"13838","DOI":"10.1073\/pnas.251531798","volume":"98","author":"YN Naumov","year":"2001","unstructured":"Naumov, Y.N. et al. Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets. Proc. Natl. Acad. Sci. USA 98, 13838\u201313843 (2001).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFni0603517_CR102","doi-asserted-by":"publisher","first-page":"6777","DOI":"10.1073\/pnas.121169698","volume":"98","author":"FD Shi","year":"2001","unstructured":"Shi, F.D. et al. Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse. Proc. Natl. Acad. Sci. USA 98, 6777\u20136782 (2001).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFni0603517_CR103","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1084\/jem.194.3.313","volume":"194","author":"B Wang","year":"2001","unstructured":"Wang, B., Geng, Y.B. & Wang, C.R. CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes. J. Exp. Med. 194, 313\u2013320 (2001).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR104","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/S1074-7613(02)00473-9","volume":"17","author":"L Beaudoin","year":"2002","unstructured":"Beaudoin, L., Laloux, V., Novak, J., Lucas, B. & Lehuen, A. NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic \u03b2 cells. Immunity 17, 725\u2013736 (2002).","journal-title":"Immunity"},{"key":"BFni0603517_CR105","doi-asserted-by":"publisher","first-page":"7411","DOI":"10.1073\/pnas.120161297","volume":"97","author":"SB Wilson","year":"2000","unstructured":"Wilson, S.B. et al. Multiple differences in gene expression in regulatory V\u03b124J\u03b1Q T cells from identical twins discordant for type I diabetes. Proc. Natl. Acad. Sci. USA 97, 7411\u20137416 (2000).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFni0603517_CR106","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1038\/34419","volume":"391","author":"SB Wilson","year":"1998","unstructured":"Wilson, S.B. et al. Extreme Th1 bias of invariant V\u03b124J\u03b1Q T cells in type 1 diabetes. Nature 391, 177\u2013181 (1998); erratum Nature 399, 84 (1999).","journal-title":"Nature"},{"key":"BFni0603517_CR107","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1172\/JCI0215832","volume":"110","author":"PT Lee","year":"2002","unstructured":"Lee, P.T. et al. Testing the NKT cell hypothesis of human IDDM pathogenesis. J. Clin. Invest. 110, 793\u2013800 (2002).","journal-title":"J. Clin. Invest."},{"key":"BFni0603517_CR108","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1084\/jem.190.9.1215","volume":"190","author":"KH Sonoda","year":"1999","unstructured":"Sonoda, K.H., Exley, M., Snapper, S., Balk, S.P. & Stein-Streilein, J. CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site. J. Exp. Med. 190, 1215\u20131226 (1999).","journal-title":"J. Exp. Med."},{"key":"BFni0603517_CR109","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1002\/1521-4141(200203)32:3<848::AID-IMMU848>3.0.CO;2-I","volume":"32","author":"KH Sonoda","year":"2002","unstructured":"Sonoda, K.H. & Stein-Streilein, J. CD1d on antigen-transporting APC and splenic marginal zone B cells promotes NKT cell-dependent tolerance. Eur. J. Immunol. 32, 848\u2013857 (2002).","journal-title":"Eur. J. Immunol."},{"key":"BFni0603517_CR110","doi-asserted-by":"publisher","first-page":"42","DOI":"10.4049\/jimmunol.166.1.42","volume":"166","author":"KH Sonoda","year":"2001","unstructured":"Sonoda, K.H. et al. NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance. J. Immunol. 166, 42\u201350 (2001).","journal-title":"J. Immunol."}],"container-title":["Nature Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/ni0603-517.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ni0603-517","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/ni0603-517.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T22:24:01Z","timestamp":1684448641000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/ni0603-517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6]]},"references-count":110,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2003,6]]}},"alternative-id":["BFni0603517"],"URL":"https:\/\/doi.org\/10.1038\/ni0603-517","relation":{},"ISSN":["1529-2908","1529-2916"],"issn-type":[{"value":"1529-2908","type":"print"},{"value":"1529-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6]]}}}