{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T10:49:47Z","timestamp":1758970187451},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Med"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1038\/nm.4425","type":"journal-article","created":{"date-parts":[[2017,10,6]],"date-time":"2017-10-06T18:02:52Z","timestamp":1507312972000},"page":"1120-1122","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Engineering MeCP2 to spy on its targets"],"prefix":"10.1038","volume":"23","author":[{"given":"Patricia M","family":"Horvath","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa M","family":"Monteggia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,10,1]]},"reference":[{"key":"BFnm4425_CR1","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1002\/ana.410140412","volume":"14","author":"B Hagberg","year":"1983","unstructured":"Hagberg, B., Aicardi, J., Dias, K. & Ramos, O. Ann. Neurol. 14, 471\u2013479 (1983).","journal-title":"Ann. Neurol."},{"key":"BFnm4425_CR2","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1038\/13810","volume":"23","author":"RE Amir","year":"1999","unstructured":"Amir, R.E. et al. Nat. Genet. 23, 185\u2013188 (1999).","journal-title":"Nat. Genet."},{"key":"BFnm4425_CR3","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1038\/30764","volume":"393","author":"X Nan","year":"1998","unstructured":"Nan, X. et al. Nature 393, 386\u2013389 (1998).","journal-title":"Nature"},{"key":"BFnm4425_CR4","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1126\/science.1153252","volume":"320","author":"M Chahrour","year":"2008","unstructured":"Chahrour, M. et al. Science 320, 1224\u20131229 (2008).","journal-title":"Science"},{"key":"BFnm4425_CR5","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.biopsych.2008.10.036","volume":"65","author":"LM Monteggia","year":"2009","unstructured":"Monteggia, L.M. & Kavalali, E.T. Biol. Psychiatry 65, 204\u2013210 (2009).","journal-title":"Biol. Psychiatry"},{"key":"BFnm4425_CR6","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.molcel.2010.01.030","volume":"37","author":"PJ Skene","year":"2010","unstructured":"Skene, P.J. et al. Mol. Cell 37, 457\u2013468 (2010).","journal-title":"Mol. Cell"},{"key":"BFnm4425_CR7","doi-asserted-by":"publisher","first-page":"15536","DOI":"10.1073\/pnas.242566899","volume":"99","author":"M Tudor","year":"2002","unstructured":"Tudor, M., Akbarian, S., Chen, R.Z. & Jaenisch, R. Proc. Acad. Sci. USA 99, 15536\u201315541 (2002).","journal-title":"Proc. Acad. Sci. USA"},{"key":"BFnm4425_CR8","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1038\/nm.4406","volume":"23","author":"B Johnson","year":"2017","unstructured":"Johnson, B. et al. Nat. Med. 23, 1203\u20131214 (2017).","journal-title":"Nat. Med."},{"key":"BFnm4425_CR9","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1136\/jmedgenet-2013-102113","volume":"51","author":"VA Cuddapah","year":"2014","unstructured":"Cuddapah, V.A. et al. J. Med. Genet. 51, 152\u2013158 (2014).","journal-title":"J. Med. Genet."},{"key":"BFnm4425_CR10","doi-asserted-by":"publisher","first-page":"12560","DOI":"10.1073\/pnas.0506071102","volume":"102","author":"VS Dani","year":"2005","unstructured":"Dani, V.S. et al. Proc. Natl. Acad. Sci. USA 102, 12560\u201312565 (2005).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnm4425_CR11","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1016\/j.cub.2006.02.062","volume":"16","author":"ED Nelson","year":"2006","unstructured":"Nelson, E.D., Kavalali, E.T. & Monteggia, L.M. Curr. Biol. 16, 710\u2013716 (2006).","journal-title":"Curr. Biol."},{"key":"BFnm4425_CR12","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1038\/nature14319","volume":"522","author":"HW Gabel","year":"2015","unstructured":"Gabel, H.W. et al. Nature 522, 89\u201393 (2015).","journal-title":"Nature"}],"container-title":["Nature Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nm.4425.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nm.4425","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/nm.4425","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/nm.4425.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T23:04:27Z","timestamp":1684451067000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nm.4425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":12,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["BFnm4425"],"URL":"https:\/\/doi.org\/10.1038\/nm.4425","relation":{},"ISSN":["1078-8956","1546-170X"],"issn-type":[{"value":"1078-8956","type":"print"},{"value":"1546-170X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"1 October 2017","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}