{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:32:51Z","timestamp":1791329571480,"version":"4.3.1"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2004,10,10]],"date-time":"2004-10-10T00:00:00Z","timestamp":1097366400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Neurosci"],"published-print":{"date-parts":[[2004,11]]},"DOI":"10.1038\/nn1332","type":"journal-article","created":{"date-parts":[[2004,10,10]],"date-time":"2004-10-10T13:05:22Z","timestamp":1097413522000},"page":"1195-1203","source":"Crossref","is-referenced-by-count":270,"title":["Par6\u03b1 signaling controls glial-guided neuronal migration"],"prefix":"10.1038","volume":"7","author":[{"given":"David J","family":"Solecki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Model","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jedidiah","family":"Gaetz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarun M","family":"Kapoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E","family":"Hatten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2004,10,10]]},"reference":[{"key":"BFnn1332_CR1","doi-asserted-by":"publisher","first-page":"1660","DOI":"10.1126\/science.1074572","volume":"297","author":"ME Hatten","year":"2002","unstructured":"Hatten, M.E. New directions in neuronal migration. Science 297, 1660\u20131663 (2002).","journal-title":"Science"},{"key":"BFnn1332_CR2","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1002\/cne.901410303","volume":"141","author":"P Rakic","year":"1971","unstructured":"Rakic, P. Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus. J. Comp. Neurol. 141, 283\u2013312 (1971).","journal-title":"J. Comp. Neurol."},{"key":"BFnn1332_CR3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/cne.901450105","volume":"145","author":"P Rakic","year":"1972","unstructured":"Rakic, P. Mode of cell migration to the superficial layers of fetal monkey neocortex. J. Comp. Neurol. 145, 61\u201383 (1972).","journal-title":"J. Comp. Neurol."},{"key":"BFnn1332_CR4","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1523\/JNEUROSCI.07-06-01928.1987","volume":"7","author":"JC Edmondson","year":"1987","unstructured":"Edmondson, J.C. & Hatten, M.E. Glial-guided granule neuron migration in vitro: a high-resolution time-lapse video microscopic study. J. Neurosci. 7, 1928\u20131934 (1987).","journal-title":"J. Neurosci."},{"key":"BFnn1332_CR5","doi-asserted-by":"publisher","first-page":"1728","DOI":"10.1523\/JNEUROSCI.08-05-01728.1988","volume":"8","author":"WA Gregory","year":"1988","unstructured":"Gregory, W.A., Edmondson, J.C., Hatten, M.E. & Mason, C.A. Cytology and neuron-glial apposition of migrating cerebellar granule cells in vitro. J. Neurosci. 8, 1728\u20131738 (1988).","journal-title":"J. Neurosci."},{"key":"BFnn1332_CR6","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1126\/science.1411527","volume":"258","author":"NA O'Rourke","year":"1992","unstructured":"O'Rourke, N.A., Dailey, M.E., Smith, S.J. & McConnell, S.K. Diverse migratory pathways in the developing cerebral cortex. Science 258, 299\u2013302 (1992).","journal-title":"Science"},{"key":"BFnn1332_CR7","doi-asserted-by":"publisher","first-page":"1478","DOI":"10.1523\/JNEUROSCI.18-04-01478.1998","volume":"18","author":"H Komuro","year":"1998","unstructured":"Komuro, H. & Rakic, P. Distinct modes of neuronal migration in different domains of developing cerebellar cortex. J. Neurosci. 18, 1478\u20131490 (1998).","journal-title":"J. Neurosci."},{"key":"BFnn1332_CR8","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1038\/83967","volume":"4","author":"B Nadarajah","year":"2001","unstructured":"Nadarajah, B., Brunstrom, J.E., Grutzendler, J., Wong, R.O. & Pearlman, A.L. Two modes of radial migration in early development of the cerebral cortex. Nat. Neurosci. 4, 143\u2013150 (2001).","journal-title":"Nat. Neurosci."},{"key":"BFnn1332_CR9","doi-asserted-by":"publisher","first-page":"4543","DOI":"10.1073\/pnas.87.12.4543","volume":"87","author":"UE Gasser","year":"1990","unstructured":"Gasser, U.E. & Hatten, M.E. Central nervous system neurons migrate on astroglial fibers from heterotypic brain regions in vitro. Proc. Natl Acad. Sci. USA 87, 4543\u20134547 (1990).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnn1332_CR10","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1523\/JNEUROSCI.15-02-00981.1995","volume":"15","author":"R Rivas","year":"1995","unstructured":"Rivas, R. & Hatten, M. Motility and cytoskeletal organization of migrating cerebellar granule neurons. J. Neurosci. 15, 981\u2013989 (1995).","journal-title":"J. Neurosci."},{"key":"BFnn1332_CR11","doi-asserted-by":"publisher","first-page":"9218","DOI":"10.1073\/pnas.93.17.9218","volume":"93","author":"P Rakic","year":"1996","unstructured":"Rakic, P., Knyihar-Csillik, E. & Csillik, B. Polarity of microtubule assemblies during neuronal cell migration. Proc. Natl Acad. Sci. USA 93, 9218\u20139222 (1996).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnn1332_CR12","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1038\/1221","volume":"19","author":"S Hirotsune","year":"1998","unstructured":"Hirotsune, S. et al. Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nat. Genet. 19, 333\u2013339 (1998).","journal-title":"Nat. Genet."},{"key":"BFnn1332_CR13","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/S0896-6273(00)80778-3","volume":"23","author":"JG Gleeson","year":"1999","unstructured":"Gleeson, J.G., Lin, P.T., Flanagan, L.A. & Walsh, C.A. Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Neuron 23, 257\u2013271 (1999).","journal-title":"Neuron"},{"key":"BFnn1332_CR14","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1038\/35041000","volume":"2","author":"DS Smith","year":"2000","unstructured":"Smith, D.S. et al. Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nat. Cell Biol. 2, 767\u2013775 (2000).","journal-title":"Nat. Cell Biol."},{"key":"BFnn1332_CR15","doi-asserted-by":"publisher","first-page":"1775","DOI":"10.1093\/hmg\/10.17.1775","volume":"10","author":"VL Sheen","year":"2001","unstructured":"Sheen, V.L. et al. Mutations in the X-linked filamin 1 gene cause periventricular nodular heterotopia in males as well as in females. Hum. Mol. Genet. 10, 1775\u20131783 (2001).","journal-title":"Hum. Mol. Genet."},{"key":"BFnn1332_CR16","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1146\/annurev.neuro.22.1.511","volume":"22","author":"ME Hatten","year":"1999","unstructured":"Hatten, M.E. Central nervous system neuronal migration. Annu. Rev. Neurosci. 22, 511\u2013539 (1999).","journal-title":"Annu. Rev. Neurosci."},{"key":"BFnn1332_CR17","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1038\/nbt0102-87","volume":"20","author":"T Nagai","year":"2002","unstructured":"Nagai, T. et al. A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications. Nat. Biotechnol. 20, 87\u201390 (2002).","journal-title":"Nat. Biotechnol."},{"key":"BFnn1332_CR18","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1083\/jcb.200203038","volume":"158","author":"AW Schaefer","year":"2002","unstructured":"Schaefer, A.W., Kabir, N. & Forscher, P. Filopodia and actin arcs guide the assembly and transport of two populations of microtubules with unique dynamic parameters in neuronal growth cones. J. Cell Biol. 158, 139\u2013152 (2002).","journal-title":"J. Cell Biol."},{"key":"BFnn1332_CR19","doi-asserted-by":"publisher","first-page":"2175","DOI":"10.1083\/jcb.99.6.2175","volume":"99","author":"WM Saxton","year":"1984","unstructured":"Saxton, W.M. et al. Tubulin dynamics in cultured mammalian cells. J. Cell Biol. 99, 2175\u20132186 (1984).","journal-title":"J. Cell Biol."},{"key":"BFnn1332_CR20","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1111\/j.1749-6632.1986.tb38434.x","volume":"466","author":"P Wadsworth","year":"1986","unstructured":"Wadsworth, P. & Salmon, E.D. Microtubule dynamics in mitotic spindles of living cells. Ann. N Y Acad. Sci. 466, 580\u2013592 (1986).","journal-title":"Ann. N Y Acad. Sci."},{"key":"BFnn1332_CR21","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/S0955-0674(02)00005-4","volume":"15","author":"S Etienne-Manneville","year":"2003","unstructured":"Etienne-Manneville, S. & Hall, A. Cell polarity: Par6, aPKC and cytoskeletal crosstalk. Curr. Opin. Cell Biol. 15, 67\u201372 (2003).","journal-title":"Curr. Opin. Cell Biol."},{"key":"BFnn1332_CR22","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/S0959-437X(03)00077-7","volume":"13","author":"D Henrique","year":"2003","unstructured":"Henrique, D. & Schweisguth, F. Cell polarity: the ups and downs of the Par6\/aPKC complex. Curr. Opin. Genet. Dev. 13, 341\u2013350 (2003).","journal-title":"Curr. Opin. Genet. Dev."},{"key":"BFnn1332_CR23","doi-asserted-by":"publisher","first-page":"6786","DOI":"10.1093\/emboj\/18.23.6786","volume":"18","author":"MP Koonce","year":"1999","unstructured":"Koonce, M.P. et al. Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome position. EMBO J. 18, 6786\u20136792 (1999).","journal-title":"EMBO J."},{"key":"BFnn1332_CR24","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/S0092-8674(01)00471-8","volume":"106","author":"S Etienne-Manneville","year":"2001","unstructured":"Etienne-Manneville, S. & Hall, A. Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell 106, 489\u2013498 (2001).","journal-title":"Cell"},{"key":"BFnn1332_CR25","doi-asserted-by":"publisher","first-page":"1871","DOI":"10.1091\/mbc.01-11-0539","volume":"13","author":"AM Yvon","year":"2002","unstructured":"Yvon, A.M. et al. Centrosome reorientation in wound-edge cells is cell type specific. Mol. Biol. Cell 13, 1871\u20131880 (2002).","journal-title":"Mol. Biol. Cell"},{"key":"BFnn1332_CR26","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1038\/345266a0","volume":"345","author":"ER Steuer","year":"1990","unstructured":"Steuer, E.R., Wordeman, L., Schroer, T.A. & Sheetz, M.P. Localization of cytoplasmic dynein to mitotic spindles and kinetochores. Nature 345, 266\u2013268 (1990).","journal-title":"Nature"},{"key":"BFnn1332_CR27","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1083\/jcb.132.4.617","volume":"132","author":"CJ Echeverri","year":"1996","unstructured":"Echeverri, C.J., Paschal, B.M., Vaughan, K.T. & Vallee, R.B. Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J. Cell Biol. 132, 617\u2013633 (1996).","journal-title":"J. Cell Biol."},{"key":"BFnn1332_CR28","doi-asserted-by":"publisher","first-page":"2676","DOI":"10.1523\/JNEUROSCI.06-09-02676.1986","volume":"6","author":"ME Hatten","year":"1986","unstructured":"Hatten, M.E., Liem, R.K. & Mason, C.A. Weaver mouse cerebellar granule neurons fail to migrate on wild-type astroglial processes in vitro. J. Neurosci. 6, 2676\u20132683 (1986).","journal-title":"J. Neurosci."},{"key":"BFnn1332_CR29","doi-asserted-by":"publisher","first-page":"1550","DOI":"10.1126\/science.1057330","volume":"291","author":"M Piel","year":"2001","unstructured":"Piel, M., Nordberg, J., Euteneuer, U. & Bornens, M. Centrosome-dependent exit of cytokinesis in animal cells. Science 291, 1550\u20131553 (2001).","journal-title":"Science"},{"key":"BFnn1332_CR30","doi-asserted-by":"crossref","first-page":"3089","DOI":"10.1242\/jcs.109.13.3089","volume":"109","author":"A Paoletti","year":"1996","unstructured":"Paoletti, A., Moudjou, M., Paintrand, M., Salisbury, J.L. & Bornens, M. Most of centrin in animal cells is not centrosome-associated and centrosomal centrin is confined to the distal lumen of centrioles. J. Cell Sci. 109, 3089\u20133102 (1996).","journal-title":"J. Cell Sci."},{"key":"BFnn1332_CR31","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1101\/gad.981002","volume":"16","author":"PJ Paddison","year":"2002","unstructured":"Paddison, P.J., Caudy, A.A., Bernstein, E., Hannon, G.J. & Conklin, D.S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16, 948\u2013958 (2002).","journal-title":"Genes Dev."},{"key":"BFnn1332_CR32","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1038\/35010544","volume":"2","author":"FJ Ahmad","year":"2000","unstructured":"Ahmad, F.J. et al. Motor proteins regulate force interactions between microtubules and microfilaments in the axon. Nat. Cell Biol. 2, 276\u2013280 (2000).","journal-title":"Nat. Cell Biol."},{"key":"BFnn1332_CR33","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1016\/S0960-9822(01)00475-4","volume":"11","author":"AF Palazzo","year":"2001","unstructured":"Palazzo, A.F. et al. Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization. Curr. Biol. 11, 1536\u20131541 (2001).","journal-title":"Curr. Biol."},{"key":"BFnn1332_CR34","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1083\/jcb.200305082","volume":"162","author":"A Burakov","year":"2003","unstructured":"Burakov, A., Nadezhdina, E., Slepchenko, B. & Rodionov, V. Centrosome positioning in interphase cells. J. Cell Biol. 162, 963\u2013969 (2003).","journal-title":"J. Cell Biol."},{"key":"BFnn1332_CR35","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1083\/jcb.200310097","volume":"163","author":"DL Dujardin","year":"2003","unstructured":"Dujardin, D.L. et al. A role for cytoplasmic dynein and LIS1 in directed cell movement. J. Cell Biol. 163, 1205\u20131211 (2003).","journal-title":"J. Cell Biol."},{"key":"BFnn1332_CR36","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/S0960-9822(98)70208-8","volume":"8","author":"S Busson","year":"1998","unstructured":"Busson, S., Dujardin, D., Moreau, A., Dompierre, J. & De Mey, J.R. Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells. Curr. Biol. 8, 541\u2013544 (1998).","journal-title":"Curr. Biol."},{"key":"BFnn1332_CR37","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/S0092-8674(01)00628-6","volume":"108","author":"D Salina","year":"2002","unstructured":"Salina, D. et al. Cytoplasmic dynein as a facilitator of nuclear envelope breakdown. Cell 108, 97\u2013107 (2002).","journal-title":"Cell"},{"key":"BFnn1332_CR38","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1002\/(SICI)1097-0169(1998)41:1<18::AID-CM2>3.0.CO;2-B","volume":"41","author":"JF Zmuda","year":"1998","unstructured":"Zmuda, J.F. & Rivas, R.J. The Golgi apparatus and the centrosome are localized to the sites of newly emerging axons in cerebellar granule neurons in vitro. Cell Motil. Cytoskeleton 41, 18\u201338 (1998).","journal-title":"Cell Motil. Cytoskeleton"},{"key":"BFnn1332_CR39","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1016\/0092-8674(95)90187-6","volume":"83","author":"B Etemad-Moghadam","year":"1995","unstructured":"Etemad-Moghadam, B., Guo, S. & Kemphues, K.J. Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos. Cell 83, 743\u2013752 (1995).","journal-title":"Cell"},{"key":"BFnn1332_CR40","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1038\/35054572","volume":"409","author":"SW Grill","year":"2001","unstructured":"Grill, S.W., Gonczy, P., Stelzer, E.H. & Hyman, A.A. Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo. Nature 409, 630\u2013633 (2001).","journal-title":"Nature"},{"key":"BFnn1332_CR41","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1083\/jcb.200209079","volume":"160","author":"MF Tsou","year":"2003","unstructured":"Tsou, M.F., Ku, W., Hayashi, A. & Rose, L.S. PAR-dependent and geometry-dependent mechanisms of spindle positioning. J. Cell Biol. 160, 845\u2013855 (2003).","journal-title":"J. Cell Biol."},{"key":"BFnn1332_CR42","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1242\/jcs.115.11.2257","volume":"115","author":"JA Kaltschmidt","year":"2002","unstructured":"Kaltschmidt, J.A. & Brand, A.H. Asymmetric cell division: microtubule dynamics and spindle asymmetry. J. Cell Sci. 115, 2257\u20132264 (2002).","journal-title":"J. Cell Sci."},{"key":"BFnn1332_CR43","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1016\/S0960-9822(03)00251-3","volume":"13","author":"JC Labbe","year":"2003","unstructured":"Labbe, J.C., Maddox, P.S., Salmon, E.D. & Goldstein, B. PAR proteins regulate microtubule dynamics at the cell cortex in C. elegans. Curr. Biol. 13, 707\u2013714 (2003).","journal-title":"Curr. Biol."},{"key":"BFnn1332_CR44","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1038\/378638a0","volume":"378","author":"M Moritz","year":"1995","unstructured":"Moritz, M., Braunfeld, M.B., Sedat, J.W., Alberts, B. & Agard, D.A. Microtubule nucleation by gamma-tubulin-containing rings in the centrosome. Nature 378, 638\u2013640 (1995).","journal-title":"Nature"},{"key":"BFnn1332_CR45","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1083\/jcb.200210171","volume":"161","author":"AF Severson","year":"2003","unstructured":"Severson, A.F. & Bowerman, B. Myosin and the PAR proteins polarize microfilament-dependent forces that shape and position mitotic spindles in Caenorhabditis elegans. J. Cell Biol. 161, 21\u201326 (2003).","journal-title":"J. Cell Biol."},{"key":"BFnn1332_CR46","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S0092-8674(04)00341-1","volume":"117","author":"J Rosenblatt","year":"2004","unstructured":"Rosenblatt, J., Cramer, L.P., Baum, B. & McGee, K.M. Myosin II-dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly. Cell 117, 361\u2013372 (2004).","journal-title":"Cell"},{"key":"BFnn1332_CR47","first-page":"85","volume":"265","author":"PJ Paddison","year":"2004","unstructured":"Paddison, P.J., Caudy, A.A., Sachidanandam, R. & Hannon, G.J. Short hairpin activated gene silencing in mammalian cells. Methods Mol. Biol. 265, 85\u2013100 (2004).","journal-title":"Methods Mol. Biol."},{"key":"BFnn1332_CR48","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/S0896-6273(01)00395-6","volume":"31","author":"DJ Solecki","year":"2001","unstructured":"Solecki, D.J., Liu, X.L., Tomoda, T., Fang, Y. & Hatten, M.E. Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation. Neuron 31, 557\u2013568 (2001).","journal-title":"Neuron"},{"key":"BFnn1332_CR49","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1083\/jcb.100.2.384","volume":"100","author":"ME Hatten","year":"1985","unstructured":"Hatten, M.E. Neuronal regulation of astroglial morphology and proliferation in vitro. J. Cell Biol. 100, 384\u2013396 (1985).","journal-title":"J. Cell Biol."},{"key":"BFnn1332_CR50","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/0165-0270(91)90128-M","volume":"37","author":"L Stoppini","year":"1991","unstructured":"Stoppini, L., Buchs, P.A. & Muller, D. A simple method for organotypic cultures of nervous tissue. J. Neurosci. Methods 37, 173\u2013182 (1991).","journal-title":"J. Neurosci. Methods"}],"container-title":["Nature Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nn1332.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nn1332","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nn1332.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T19:53:55Z","timestamp":1684439635000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nn1332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10,10]]},"references-count":50,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["BFnn1332"],"URL":"https:\/\/doi.org\/10.1038\/nn1332","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1021822.255650","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1021822.248654","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1021822.263678","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1021822.263641","asserted-by":"object"}]},"ISSN":["1097-6256","1546-1726"],"issn-type":[{"value":"1097-6256","type":"print"},{"value":"1546-1726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,10,10]]}}}