{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:39:13Z","timestamp":1791160753623,"version":"4.1.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2012,10,4]],"date-time":"2012-10-04T00:00:00Z","timestamp":1349308800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Protoc"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1038\/nprot.2012.110","type":"journal-article","created":{"date-parts":[[2012,10,4]],"date-time":"2012-10-04T15:17:45Z","timestamp":1349363865000},"page":"1956-1963","source":"Crossref","is-referenced-by-count":34,"title":["Synthesis of [18F]SiFB: a prosthetic group for direct protein radiolabeling for application in positron emission tomography"],"prefix":"10.1038","volume":"7","author":[{"given":"Alexey P","family":"Kostikov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Chin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katy","family":"Orchowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Schirrmacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Niedermoser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Jurkschat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liuba","family":"Iovkova-Berends","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"W\u00e4ngler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"W\u00e4ngler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Schirrmacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,10,4]]},"reference":[{"key":"BFnprot2012110_CR1","first-page":"275","volume":"19","author":"G Vaidyanathan","year":"1992","unstructured":"Vaidyanathan, G. & Zalutsky, M.R. Labeling proteins with fluorine-18 using N-succinimidyl 4-[18F]fluorobenzoate. Nucl. Med. Biol. 19, 275\u2013281 (1992).","journal-title":"Nucl. Med. Biol."},{"key":"BFnprot2012110_CR2","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1021\/bc00028a012","volume":"5","author":"G Vaidyanathan","year":"1994","unstructured":"Vaidyanathan, G. & Zalutsky, M.R. Improved synthesis of N-succinimidyl 4-[18F]fluorobenzoate and its application to the labeling of a monoclonal antibody fragment. Bioconjug. Chem. 5, 352\u2013356 (1994).","journal-title":"Bioconjug. Chem."},{"key":"BFnprot2012110_CR3","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/0969-8051(96)00017-0","volume":"23","author":"HJ Wester","year":"1996","unstructured":"Wester, H.J., Hamacher, K. & St\u00f6cklin, G.A. A Comparative study of N.C.A. Fluorine-18 labeling of proteins via acylation and photochemical conjugation. Nucl. Med. Biol. 23, 365\u2013372 (1996).","journal-title":"Nucl. Med. Biol."},{"key":"BFnprot2012110_CR4","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1016\/j.nucmedbio.2004.02.007","volume":"31","author":"J Toretsky","year":"2004","unstructured":"Toretsky, J. et al. Preparation of F-18 labeled annexin V: a potential PET radiopharmaceutical for imaging cell death. Nucl. Med. Biol. 31, 747\u2013752 (2004).","journal-title":"Nucl. Med. Biol."},{"key":"BFnprot2012110_CR5","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/S0969-8043(03)00161-1","volume":"59","author":"F W\u00fcst","year":"2003","unstructured":"W\u00fcst, F., Hultsch, C., Bergmann, R., Johanssen, B. & Henle, T. Radiolabelling of isopeptide N\u025b-(\u03b3-glutamyl)-L-lysine by conjugation with N-succinimidyl-4-[18F]fluorobenzoate. Appl. Radiat. Isot. 59, 43\u201348 (2003).","journal-title":"Appl. Radiat. Isot."},{"key":"BFnprot2012110_CR6","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1002\/jlcr.1758","volume":"53","author":"G Tang","year":"2010","unstructured":"Tang, G., Tang, X. & Wang, X. A facile automated synthesis of N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB) for 18F-labeled cell-penetrating peptide as PET tracer. J. Label Compd. Radiopharm 53, 543\u2013547 (2010).","journal-title":"J. Label Compd. Radiopharm"},{"key":"BFnprot2012110_CR7","doi-asserted-by":"publisher","first-page":"2853","DOI":"10.1002\/ejoc.200800114","volume":"2008","author":"L Cai","year":"2008","unstructured":"Cai, L., Lu, S. & Pike, V.W. Chemistry with [18F]fluoride ion. Eur. J. Org. Chem. 2008, 2853\u20132873 (2008).","journal-title":"Eur. J. Org. Chem."},{"key":"BFnprot2012110_CR8","doi-asserted-by":"publisher","first-page":"6196","DOI":"10.1039\/c0dt01594f","volume":"40","author":"GE Smith","year":"2011","unstructured":"Smith, G.E., Sladen, H.L., Biagini, C.G. & Blower, P.J. Inorganic approaches for radiolabelling biomolecules with fluorine-18 for imaging with positron emission tomography. Dalton Trans. 40, 6196\u20136205 (2011).","journal-title":"Dalton Trans."},{"key":"BFnprot2012110_CR9","doi-asserted-by":"publisher","first-page":"224","DOI":"10.2174\/1874471011003030224","volume":"3","author":"L Mu","year":"2010","unstructured":"Mu, L., Schubiger, A.P. & Ametamey, S.M. [18F]fluorosilicon- and [18F]fluoroboron-based biomolecules for PET imaging. Curr. Radiopharm. 3, 224\u2013242 (2010).","journal-title":"Curr. Radiopharm."},{"key":"BFnprot2012110_CR10","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2174\/157019309787316148","volume":"6","author":"C Mamat","year":"2009","unstructured":"Mamat, C., Ramenda, T. & Wuest, F.R. Recent applications of click chemistry for the synthesis of radiotracers for molecular imaging. Mini-Rev. Org. Chem. 6, 21\u201334 (2009).","journal-title":"Mini-Rev. Org. Chem."},{"key":"BFnprot2012110_CR11","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.2174\/092986710790820615","volume":"17","author":"C W\u00e4ngler","year":"2010","unstructured":"W\u00e4ngler, C., Schirrmacher, R., Bartenstein, P. & W\u00e4ngler, B. Click-chemistry reactions in radiopharmaceutical chemistry: fast & easy introduction of radiolabels into biomolecules for in vivo imaging. Curr. Med. Chem. 17, 1092\u2013116 (2010).","journal-title":"Curr. Med. Chem."},{"key":"BFnprot2012110_CR12","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1002\/jlcr.1656","volume":"52","author":"M Glaser","year":"2009","unstructured":"Glaser, M. & Robins, E.G. Click labelling in PET radiochemistry. J. Label Compd. Radiopharm. 52, 407\u2013414 (2009).","journal-title":"J. Label Compd. Radiopharm."},{"key":"BFnprot2012110_CR13","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1038\/nprot.2012.109","volume":"7","author":"C W\u00e4ngler","year":"2012","unstructured":"W\u00e4ngler, C. et al. One-step 18F-labeling of peptides for positron emission tomography imaging using the SiFA methodology. Nat. Protoc. 7, 1946\u20131955 (2012).","journal-title":"Nat. Protoc."},{"key":"BFnprot2012110_CR14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1055\/s-0037-1621960","volume":"51","author":"S Wessmann","year":"2012","unstructured":"Wessmann, S., Henriksen, G. & Wester, H.J. Cryptate mediated nucleophilic 18F\u2212fluorination without azeotropic drying. Nuklearmedizin. 51, 1\u201331 (2012).","journal-title":"Nuklearmedizin."},{"key":"BFnprot2012110_CR15","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1021\/bc200525x","volume":"23","author":"AP Kostikov","year":"2012","unstructured":"Kostikov, A.P. et al. Oxalic acid supported Si-18F radiofluorination: one step radiosynthesis of N-succinimidyl-3-(di-tert-butyl[18F]fluorosilyl)benzoate ([18F]SiFB) for protein labeling. Bioconjug. Chem. 23, 104\u2013114 (2012).","journal-title":"Bioconjug. Chem."},{"key":"BFnprot2012110_CR16","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1016\/0161-5890(95)00052-G","volume":"32","author":"TK Nikula","year":"1995","unstructured":"Nikula, T.K. et al. Impact of high tyrosine fraction in complementary determining regions: measured and predicted effects of radioiodination on IgG immunoreactivity. Mol. Immunol. 32, 865\u2013872 (1995).","journal-title":"Mol. Immunol."},{"key":"BFnprot2012110_CR17","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1021\/bc700308q","volume":"19","author":"C W\u00e4ngler","year":"2008","unstructured":"W\u00e4ngler, C., Moldenhauer, G., Eisenhut, M., Haberkorn, U. & Mier, W. Antibody-dendrimer conjugates: the number, not the size of the dendrimers, determines the immunoreactivity. Bioconjug. Chem. 19, 813\u2013820 (2008).","journal-title":"Bioconjug. Chem."},{"key":"BFnprot2012110_CR18","doi-asserted-by":"publisher","first-page":"1964","DOI":"10.1038\/nprot.2012.111","volume":"7","author":"B W\u00e4ngler","year":"2012","unstructured":"W\u00e4ngler, B. et al. Protein labeling with the labeling precursor [18F]SiFA-SH for positron emission tomography. Nat. Protoc. 7, 1964\u20131969 (2012).","journal-title":"Nat. Protoc."}],"container-title":["Nature Protocols"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nprot.2012.110.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nprot.2012.110","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nprot.2012.110.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T02:21:14Z","timestamp":1687746074000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nprot.2012.110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,4]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["BFnprot2012110"],"URL":"https:\/\/doi.org\/10.1038\/nprot.2012.110","relation":{},"ISSN":["1754-2189","1750-2799"],"issn-type":[{"value":"1754-2189","type":"print"},{"value":"1750-2799","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,4]]}}}