{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T07:10:10Z","timestamp":1791529810446,"version":"4.3.4"},"reference-count":76,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T00:00:00Z","timestamp":1374710400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Protoc"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1038\/nprot.2013.094","type":"journal-article","created":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T11:40:37Z","timestamp":1374752437000},"page":"1583-1601","source":"Crossref","is-referenced-by-count":303,"title":["Design and generation of recombinant rabies virus vectors"],"prefix":"10.1038","volume":"8","author":[{"given":"Fumitaka","family":"Osakada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward M","family":"Callaway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,7,25]]},"reference":[{"key":"BFnprot2013094_CR1","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/j.neuron.2008.01.002","volume":"57","author":"L Luo","year":"2008","unstructured":"Luo, L., Callaway, E.M. & Svoboda, K. Genetic dissection of neural circuits. Neuron 57, 634\u2013660 (2008).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR2","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1038\/nature08536","volume":"461","author":"BR Arenkiel","year":"2009","unstructured":"Arenkiel, B.R. & Ehlers, M.D. Molecular genetics and imaging technologies for circuit-based neuroanatomy. Nature 461, 900\u2013907 (2009).","journal-title":"Nature"},{"key":"BFnprot2013094_CR3","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1038\/nature08540","volume":"461","author":"M Scanziani","year":"2009","unstructured":"Scanziani, M. & Hausser, M. Electrophysiology in the age of light. Nature 461, 930\u2013939 (2009).","journal-title":"Nature"},{"key":"BFnprot2013094_CR4","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.neuron.2011.06.004","volume":"71","author":"O Yizhar","year":"2011","unstructured":"Yizhar, O., Fenno, L.E., Davidson, T.J., Mogri, M. & Deisseroth, K. Optogenetics in neural systems. Neuron 71, 9\u201334 (2011).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR5","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1038\/nrn3136","volume":"13","author":"M Carandini","year":"2011","unstructured":"Carandini, M. & Heeger, D.J. Normalization as a canonical neural computation. Nat. Rev. Neurosci. 13, 51\u201362 (2011).","journal-title":"Nat. Rev. Neurosci."},{"key":"BFnprot2013094_CR6","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1038\/nmeth999","volume":"4","author":"IR Wickersham","year":"2007","unstructured":"Wickersham, I.R., Finke, S., Conzelmann, K.K. & Callaway, E.M. Retrograde neuronal tracing with a deletion-mutant rabies virus. Nat. Methods 4, 47\u201349 (2007).","journal-title":"Nat. Methods"},{"key":"BFnprot2013094_CR7","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.neuron.2007.01.033","volume":"53","author":"IR Wickersham","year":"2007","unstructured":"Wickersham, I.R. et al. Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons. Neuron 53, 639\u2013647 (2007).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR8","first-page":"5","volume":"1","author":"DD Larsen","year":"2007","unstructured":"Larsen, D.D., Wickersham, I.R. & Callaway, E.M. Retrograde tracing with recombinant rabies virus reveals correlations between projection targets and dendritic architecture in layer 5 of mouse barrel cortex. Front Neural Circuits 1, 5 (2007).","journal-title":"Front Neural Circuits"},{"key":"BFnprot2013094_CR9","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1016\/j.neuron.2007.07.037","volume":"55","author":"JJ Nassi","year":"2007","unstructured":"Nassi, J.J. & Callaway, E.M. Specialized circuits from primary visual cortex to V2 and area MT. Neuron 55, 799\u2013808 (2007).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR10","doi-asserted-by":"publisher","first-page":"16703","DOI":"10.1073\/pnas.1006233107","volume":"107","author":"J Choi","year":"2010","unstructured":"Choi, J., Young, J.A. & Callaway, E.M. Selective viral vector transduction of ErbB4-expressing cortical interneurons in vivo with a viral receptor-ligand bridge protein. Proc. Natl Acad. Sci. USA 107, 16703\u201316708 (2010).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnprot2013094_CR11","doi-asserted-by":"publisher","first-page":"21848","DOI":"10.1073\/pnas.1011756107","volume":"107","author":"NR Wall","year":"2010","unstructured":"Wall, N.R., Wickersham, I.R., Cetin, A., De La Parra, M. & Callaway, E.M. Monosynaptic circuit tracing in vivo through Cre-dependent targeting and complementation of modified rabies virus. Proc. Natl Acad. Sci. USA 107, 21848\u201321853 (2010).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnprot2013094_CR12","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.neuron.2010.08.001","volume":"67","author":"JH Marshel","year":"2010","unstructured":"Marshel, J.H., Mori, T., Nielsen, K.J. & Callaway, E.M. Targeting single neuronal networks for gene expression and cell labeling in vivo. Neuron 67, 562\u2013574 (2010).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR13","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/j.neuron.2011.07.005","volume":"71","author":"F Osakada","year":"2011","unstructured":"Osakada, F. et al. New rabies virus variants for monitoring and manipulating activity and gene expression in defined neural circuits. Neuron 71, 617\u2013631 (2011).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR14","doi-asserted-by":"publisher","first-page":"3402","DOI":"10.1002\/cne.22680","volume":"519","author":"J Choi","year":"2011","unstructured":"Choi, J. & Callaway, E.M. Monosynaptic inputs to ErbB4-expressing inhibitory neurons in mouse primary somatosensory cortex. J. Comp. Neurol. 519, 3402\u20133414 (2011).","journal-title":"J. Comp. Neurol."},{"key":"BFnprot2013094_CR15","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1002\/cne.22685","volume":"520","author":"HL Nhan","year":"2012","unstructured":"Nhan, H.L. & Callaway, E.M. Morphology of superior colliculus- and middle temporal area-projecting neurons in primate primary visual cortex. J. Comp. Neurol. 520, 52\u201380 (2012).","journal-title":"J. Comp. Neurol."},{"key":"BFnprot2013094_CR16","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/j.neuron.2010.10.019","volume":"68","author":"AE Stepien","year":"2010","unstructured":"Stepien, A.E., Tripodi, M. & Arber, S. Monosynaptic rabies virus reveals premotor network organization and synaptic specificity of cholinergic partition cells. Neuron 68, 456\u2013472 (2010).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR17","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1038\/nature09553","volume":"468","author":"W Haubensak","year":"2010","unstructured":"Haubensak, W. et al. Genetic dissection of an amygdala microcircuit that gates conditioned fear. Nature 468, 270\u2013276 (2010).","journal-title":"Nature"},{"key":"BFnprot2013094_CR18","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1038\/nature09711","volume":"469","author":"K Yonehara","year":"2011","unstructured":"Yonehara, K. et al. Spatially asymmetric reorganization of inhibition establishes a motion-sensitive circuit. Nature 469, 407\u2013410 (2011).","journal-title":"Nature"},{"key":"BFnprot2013094_CR19","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1038\/nature09714","volume":"472","author":"K Miyamichi","year":"2011","unstructured":"Miyamichi, K. et al. Cortical representations of olfactory input by trans-synaptic tracing. Nature 472, 191\u2013196 (2011).","journal-title":"Nature"},{"key":"BFnprot2013094_CR20","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1038\/nn.2765","volume":"14","author":"EA Rancz","year":"2011","unstructured":"Rancz, E.A. et al. Transfection via whole-cell recording in vivo: bridging single-cell physiology, genetics and connectomics. Nat. Neurosci. 14, 527\u2013532 (2011).","journal-title":"Nat. Neurosci."},{"key":"BFnprot2013094_CR21","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1038\/nature10538","volume":"479","author":"M Tripodi","year":"2011","unstructured":"Tripodi, M., Stepien, A.E. & Arber, S. Motor antagonism exposed by spatial segregation and timing of neurogenesis. Nature 479, 61\u201366 (2011).","journal-title":"Nature"},{"key":"BFnprot2013094_CR22","doi-asserted-by":"publisher","first-page":"4992","DOI":"10.1523\/JNEUROSCI.4759-11.2012","volume":"32","author":"T Kiritani","year":"2012","unstructured":"Kiritani, T., Wickersham, I.R., Seung, H.S. & Shepherd, G.M. Hierarchical connectivity and connection-specific dynamics in the corticospinal-corticostriatal microcircuit in mouse motor cortex. J. Neurosci. 32, 4992\u20135001 (2012).","journal-title":"J. Neurosci."},{"key":"BFnprot2013094_CR23","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1016\/j.neuron.2012.03.017","volume":"74","author":"M Watabe-Uchida","year":"2012","unstructured":"Watabe-Uchida, M., Zhu, L., Ogawa, S.K., Vamanrao, A. & Uchida, N. Whole-brain mapping of direct inputs to midbrain dopamine neurons. Neuron 74, 858\u2013873 (2012).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR24","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1038\/ncomms2101","volume":"3","author":"C Vivar","year":"2012","unstructured":"Vivar, C. et al. Monosynaptic inputs to new neurons in the dentate gyrus. Nat. Commun. 3, 1107 (2012).","journal-title":"Nat. Commun."},{"key":"BFnprot2013094_CR25","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/j.neuron.2012.11.010","volume":"77","author":"J Takatoh","year":"2012","unstructured":"Takatoh, J. et al. New modules are added to vibrissal premotor circuitry with the emergence of exploratory whisking. Neuron 77, 346\u2013360 (2012).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR26","doi-asserted-by":"publisher","first-page":"2140","DOI":"10.1002\/stem.1185","volume":"30","author":"I Garcia","year":"2012","unstructured":"Garcia, I., Huang, L., Ung, K. & Arenkiel, B.R. Tracing synaptic connectivity onto embryonic stem cell-derived neurons. Stem Cells 30, 2140\u20132151 (2012).","journal-title":"Stem Cells"},{"key":"BFnprot2013094_CR27","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1038\/nature11527","volume":"491","author":"S Lammel","year":"2012","unstructured":"Lammel, S. et al. Input-specific control of reward and aversion in the ventral tegmental area. Nature 491, 212\u2013217 (2012).","journal-title":"Nature"},{"key":"BFnprot2013094_CR28","doi-asserted-by":"publisher","first-page":"2415","DOI":"10.1152\/jn.01043.2012","volume":"109","author":"L Yin","year":"2013","unstructured":"Yin, L. et al. Imaging light responses of retinal ganglion cells in the living mouse eye. J. Neurophysiol. 109, 2415\u20132421 (2013).","journal-title":"J. Neurophysiol."},{"key":"BFnprot2013094_CR29","doi-asserted-by":"publisher","first-page":"9106","DOI":"10.1073\/pnas.1306912110","volume":"110","author":"Y Li","year":"2013","unstructured":"Li, Y. et al. Molecular layer perforant path-associated cells contribute to feed-forward inhibition in the adult dentate gyrus. Proc. Natl Acad. Sci. USA 110, 9106\u20139111 (2013).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnprot2013094_CR30","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1002\/cne.903560312","volume":"356","author":"G Ugolini","year":"1995","unstructured":"Ugolini, G. Specificity of rabies virus as a transneuronal tracer of motor networks: transfer from hypoglossal motoneurons to connected second-order and higher order central nervous system cell groups. J. Comp. Neurol. 356, 457\u2013480 (1995).","journal-title":"J. Comp. Neurol."},{"key":"BFnprot2013094_CR31","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.jneumeth.2009.12.001","volume":"194","author":"G Ugolini","year":"2010","unstructured":"Ugolini, G. Advances in viral transneuronal tracing. J. Neurosci. Methods 194, 2\u201320 (2010).","journal-title":"J. Neurosci. Methods"},{"key":"BFnprot2013094_CR32","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/j.conb.2009.03.007","volume":"18","author":"EM Callaway","year":"2008","unstructured":"Callaway, E.M. Transneuronal circuit tracing with neurotropic viruses. Curr. Opin. Neurobiol. 18, 617\u2013623 (2008).","journal-title":"Curr. Opin. Neurobiol."},{"key":"BFnprot2013094_CR33","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1016\/S0092-8674(00)81072-7","volume":"84","author":"T Mebatsion","year":"1996","unstructured":"Mebatsion, T., Konig, M. & Conzelmann, K.K. Budding of rabies virus particles in the absence of the spike glycoprotein. Cell 84, 941\u2013951 (1996).","journal-title":"Cell"},{"key":"BFnprot2013094_CR34","doi-asserted-by":"publisher","first-page":"2147","DOI":"10.1099\/0022-1317-81-9-2147","volume":"81","author":"R Etessami","year":"2000","unstructured":"Etessami, R. et al. Spread and pathogenic characteristics of a G-deficient rabies virus recombinant: an in vitro and in vivo study. J. Gen. Virol. 81, 2147\u20132153 (2000).","journal-title":"J. Gen. Virol."},{"key":"BFnprot2013094_CR35","doi-asserted-by":"publisher","first-page":"16509","DOI":"10.1523\/JNEUROSCI.2442-10.2010","volume":"30","author":"AP Weible","year":"2010","unstructured":"Weible, A.P. et al. Transgenic targeting of recombinant rabies virus reveals monosynaptic connectivity of specific neurons. J. Neurosci. 30, 16509\u201316513 (2010).","journal-title":"J. Neurosci."},{"key":"BFnprot2013094_CR36","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1038\/nmeth.1398","volume":"6","author":"L Tian","year":"2009","unstructured":"Tian, L. et al. Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nat. Methods 6, 875\u2013881 (2009).","journal-title":"Nat. Methods"},{"key":"BFnprot2013094_CR37","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1038\/nmeth.1243","volume":"5","author":"M Mank","year":"2008","unstructured":"Mank, M. et al. A genetically encoded calcium indicator for chronic in vivo two-photon imaging. Nat. Methods 5, 805\u2013811 (2008).","journal-title":"Nat. Methods"},{"key":"BFnprot2013094_CR38","doi-asserted-by":"publisher","first-page":"e39933","DOI":"10.1371\/journal.pone.0039933","volume":"7","author":"M Ohkura","year":"2012","unstructured":"Ohkura, M., Sasaki, T., Kobayashi, C., Ikegaya, Y. & Nakai, J. An improved genetically encoded red fluorescent Ca2+ indicator for detecting optically evoked action potentials. PLoS ONE 7, e39933 (2012).","journal-title":"PLoS ONE"},{"key":"BFnprot2013094_CR39","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1038\/nmeth.1479","volume":"7","author":"W Akemann","year":"2010","unstructured":"Akemann, W., Mutoh, H., Perron, A., Rossier, J. & Knopfel, T. Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins. Nat. Methods 7, 643\u2013649 (2010).","journal-title":"Nat. Methods"},{"key":"BFnprot2013094_CR40","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1038\/nmeth.1782","volume":"9","author":"JM Kralj","year":"2012","unstructured":"Kralj, J.M., Douglass, A.D., Hochbaum, D.R., Maclaurin, D. & Cohen, A.E. Optical recording of action potentials in mammalian neurons using a microbial rhodopsin. Nat. Methods 9, 90\u201395 (2012).","journal-title":"Nat. Methods"},{"key":"BFnprot2013094_CR41","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1038\/nmeth.2333","volume":"10","author":"JS Marvin","year":"2013","unstructured":"Marvin, J.S. et al. An optimized fluorescent probe for visualizing glutamate neurotransmission. Nat. Methods 10, 162\u2013170 (2013).","journal-title":"Nat. Methods"},{"key":"BFnprot2013094_CR42","doi-asserted-by":"publisher","first-page":"5287","DOI":"10.1523\/JNEUROSCI.22-13-05287.2002","volume":"22","author":"HA Lechner","year":"2002","unstructured":"Lechner, H.A., Lein, E.S. & Callaway, E.M. A genetic method for selective and quickly reversible silencing of mammalian neurons. J. Neurosci. 22, 5287\u20135290 (2002).","journal-title":"J. Neurosci."},{"key":"BFnprot2013094_CR43","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.neuron.2006.06.018","volume":"51","author":"EM Tan","year":"2006","unstructured":"Tan, E.M. et al. Selective and quickly reversible inactivation of mammalian neurons in vivo using the Drosophila allatostatin receptor. Neuron 51, 157\u2013170 (2006).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR44","doi-asserted-by":"publisher","first-page":"5163","DOI":"10.1073\/pnas.0700293104","volume":"104","author":"BN Armbruster","year":"2007","unstructured":"Armbruster, B.N., Li, X., Pausch, M.H., Herlitze, S. & Roth, B.L. Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand. Proc. Natl Acad. Sci. USA 104, 5163\u20135168 (2007).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnprot2013094_CR45","doi-asserted-by":"publisher","first-page":"1292","DOI":"10.1126\/science.1206606","volume":"333","author":"CJ Magnus","year":"2011","unstructured":"Magnus, C.J. et al. Chemical and genetic engineering of selective ion channel-ligand interactions. Science 333, 1292\u20131296 (2011).","journal-title":"Science"},{"key":"BFnprot2013094_CR46","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1038\/nn1525","volume":"8","author":"ES Boyden","year":"2005","unstructured":"Boyden, E.S., Zhang, F., Bamberg, E., Nagel, G. & Deisseroth, K. Millisecond-timescale, genetically targeted optical control of neural activity. Nat. Neurosci. 8, 1263\u20131268 (2005).","journal-title":"Nat. Neurosci."},{"key":"BFnprot2013094_CR47","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.cell.2010.02.037","volume":"141","author":"V Gradinaru","year":"2010","unstructured":"Gradinaru, V. et al. Molecular and cellular approaches for diversifying and extending optogenetics. Cell 141, 154\u2013165 (2010).","journal-title":"Cell"},{"key":"BFnprot2013094_CR48","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1038\/nature08652","volume":"463","author":"BY Chow","year":"2010","unstructured":"Chow, B.Y. et al. High-performance genetically targetable optical neural silencing by light-driven proton pumps. Nature 463, 98\u2013102 (2010).","journal-title":"Nature"},{"key":"BFnprot2013094_CR49","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1038\/nn1891","volume":"10","author":"L Petreanu","year":"2007","unstructured":"Petreanu, L., Huber, D., Sobczyk, A. & Svoboda, K. Channelrhodopsin-2\u2013assisted circuit mapping of long-range callosal projections. Nat. Neurosci. 10, 663\u2013668 (2007).","journal-title":"Nat. Neurosci."},{"key":"BFnprot2013094_CR50","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1038\/nature09108","volume":"465","author":"JH Lee","year":"2010","unstructured":"Lee, J.H. et al. Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. Nature 465, 788\u2013792 (2010).","journal-title":"Nature"},{"key":"BFnprot2013094_CR51","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.virol.2005.09.021","volume":"344","author":"RJ Barnard","year":"2006","unstructured":"Barnard, R.J., Elleder, D. & Young, J.A. Avian sarcoma and leukosis virus-receptor interactions: from classical genetics to novel insights into virus-cell membrane fusion. Virology 344, 25\u201329 (2006).","journal-title":"Virology"},{"key":"BFnprot2013094_CR52","doi-asserted-by":"publisher","first-page":"10137","DOI":"10.1073\/pnas.0800487105","volume":"105","author":"B Seidler","year":"2008","unstructured":"Seidler, B. et al. A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors. Proc. Natl Acad. Sci. USA 105, 10137\u201310142 (2008).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnprot2013094_CR53","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/nn.2467","volume":"13","author":"L Madisen","year":"2010","unstructured":"Madisen, L. et al. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat. Neurosci. 13, 133\u2013140 (2010).","journal-title":"Nat. Neurosci."},{"key":"BFnprot2013094_CR54","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1016\/j.neuron.2011.07.026","volume":"71","author":"H Taniguchi","year":"2011","unstructured":"Taniguchi, H. et al. A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex. Neuron 71, 995\u20131013 (2011).","journal-title":"Neuron"},{"key":"BFnprot2013094_CR55","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1038\/nn.3078","volume":"15","author":"L Madisen","year":"2012","unstructured":"Madisen, L. et al. A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing. Nat. Neurosci. 15, 793\u2013802 (2012).","journal-title":"Nat. Neurosci."},{"key":"BFnprot2013094_CR56","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1038\/nrmicro2260","volume":"8","author":"MJ Schnell","year":"2010","unstructured":"Schnell, M.J., McGettigan, J.P., Wirblich, C. & Papaneri, A. The cell biology of rabies virus: using stealth to reach the brain. Nat. Rev. Microbiol. 8, 51\u201361 (2010).","journal-title":"Nat. Rev. Microbiol."},{"key":"BFnprot2013094_CR57","doi-asserted-by":"publisher","first-page":"1613","DOI":"10.1099\/vir.0.19128-0","volume":"84","author":"S Finke","year":"2003","unstructured":"Finke, S., Mueller-Waldeck, R. & Conzelmann, K.K. Rabies virus matrix protein regulates the balance of virus transcription and replication. J. Gen. Virol. 84, 1613\u20131621 (2003).","journal-title":"J. Gen. Virol."},{"key":"BFnprot2013094_CR58","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1126\/science.1088547","volume":"302","author":"S Hacein-Bey-Abina","year":"2003","unstructured":"Hacein-Bey-Abina, S. et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302, 415\u2013419 (2003).","journal-title":"Science"},{"key":"BFnprot2013094_CR59","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1038\/nrg2937","volume":"12","author":"F Gonzalez","year":"2011","unstructured":"Gonzalez, F., Boue, S. & Izpisua Belmonte, J.C. Methods for making induced pluripotent stem cells: reprogramming a la carte. Nat. Rev. Genet. 12, 231\u2013242 (2011).","journal-title":"Nat. Rev. Genet."},{"key":"BFnprot2013094_CR60","doi-asserted-by":"publisher","first-page":"4195","DOI":"10.1002\/j.1460-2075.1994.tb06739.x","volume":"13","author":"MJ Schnell","year":"1994","unstructured":"Schnell, M.J., Mebatsion, T. & Conzelmann, K.K. Infectious rabies viruses from cloned cDNA. EMBO J. 13, 4195\u20134203 (1994).","journal-title":"EMBO J."},{"key":"BFnprot2013094_CR61","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1038\/nprot.2009.248","volume":"5","author":"IR Wickersham","year":"2010","unstructured":"Wickersham, I.R., Sullivan, H.A. & Seung, H.S. Production of glycoprotein-deleted rabies viruses for monosynaptic tracing and high-level gene expression in neurons. Nat. Protoc. 5, 595\u2013606 (2010).","journal-title":"Nat. Protoc."},{"key":"BFnprot2013094_CR62","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/0042-6822(90)90433-R","volume":"175","author":"KK Conzelmann","year":"1990","unstructured":"Conzelmann, K.K., Cox, J.H., Schneider, L.G. & Thiel, H.J. Molecular cloning and complete nucleotide sequence of the attenuated rabies virus SAD B19. Virology 175, 485\u2013499 (1990).","journal-title":"Virology"},{"key":"BFnprot2013094_CR63","doi-asserted-by":"publisher","first-page":"3544","DOI":"10.1073\/pnas.97.7.3544","volume":"97","author":"MJ Schnell","year":"2000","unstructured":"Schnell, M.J. et al. Recombinant rabies virus as potential live-viral vaccines for HIV-1. Proc. Natl Acad. Sci. USA 97, 3544\u20133549 (2000).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnprot2013094_CR64","doi-asserted-by":"publisher","first-page":"11366","DOI":"10.1073\/pnas.93.21.11366","volume":"93","author":"T Mebatsion","year":"1996","unstructured":"Mebatsion, T. & Conzelmann, K.K. Specific infection of CD4+ target cells by recombinant rabies virus pseudotypes carrying the HIV-1 envelope spike protein. Proc. Natl Acad. Sci. USA 93, 11366\u201311370 (1996).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnprot2013094_CR65","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1089\/hum.2007.082","volume":"18","author":"S Kato","year":"2007","unstructured":"Kato, S. et al. Efficient gene transfer via retrograde transport in rodent and primate brains using a human immunodeficiency virus type 1-based vector pseudotyped with rabies virus glycoprotein. Hum. Gene Ther. 18, 1141\u20131151 (2007).","journal-title":"Hum. Gene Ther."},{"key":"BFnprot2013094_CR66","doi-asserted-by":"publisher","first-page":"2109","DOI":"10.1093\/hmg\/10.19.2109","volume":"10","author":"ND Mazarakis","year":"2001","unstructured":"Mazarakis, N.D. et al. Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery. Hum. Mol. Genet. 10, 2109\u20132121 (2001).","journal-title":"Hum. Mol. Genet."},{"key":"BFnprot2013094_CR67","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1080\/13550280590900427","volume":"11","author":"M Lafon","year":"2005","unstructured":"Lafon, M. Rabies virus receptors. J. Neurovirol. 11, 82\u201387 (2005).","journal-title":"J. Neurovirol."},{"key":"BFnprot2013094_CR68","unstructured":"Green, M.R. & Sambrook, J. Molecular Cloning: A Laboratory Manual (Fourth ed.) (Cold Spring Harbor Laboratory Press, 2012)."},{"key":"BFnprot2013094_CR69","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1002\/j.1460-2075.1994.tb06337.x","volume":"13","author":"MD Ryan","year":"1994","unstructured":"Ryan, M.D. & Drew, J. Foot-and-mouth disease virus 2A oligopeptide mediated cleavage of an artificial polyprotein. EMBO J. 13, 928\u2013933 (1994).","journal-title":"EMBO J."},{"key":"BFnprot2013094_CR70","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1093\/embo-reports\/kve208","volume":"2","author":"S Vagner","year":"2001","unstructured":"Vagner, S., Galy, B. & Pyronnet, S. Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites. EMBO Rep. 2, 893\u2013898 (2001).","journal-title":"EMBO Rep."},{"key":"BFnprot2013094_CR71","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1634\/stemcells.2006-0813","volume":"25","author":"K Hasegawa","year":"2007","unstructured":"Hasegawa, K., Cowan, A.B., Nakatsuji, N. & Suemori, H. Efficient multicistronic expression of a transgene in human embryonic stem cells. Stem Cells 25, 1707\u20131712 (2007).","journal-title":"Stem Cells"},{"key":"BFnprot2013094_CR72","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1006\/mthe.2000.0050","volume":"1","author":"H Mizuguchi","year":"2000","unstructured":"Mizuguchi, H., Xu, Z., Ishii-Watabe, A., Uchida, E. & Hayakawa, T. IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector. Mol. Ther. 1, 376\u2013382 (2000).","journal-title":"Mol. Ther."},{"key":"BFnprot2013094_CR73","doi-asserted-by":"publisher","first-page":"2024","DOI":"10.1128\/JVI.76.4.2024-2027.2002","volume":"76","author":"P Le Mercier","year":"2002","unstructured":"Le Mercier, P., Jacob, Y., Tanner, K. & Tordo, N. A novel expression cassette of lyssavirus shows that the distantly related Mokola virus can rescue a defective rabies virus genome. J. Virol. 76, 2024\u20132027 (2002).","journal-title":"J. Virol."},{"key":"BFnprot2013094_CR74","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1146\/annurev.bi.61.070192.003233","volume":"61","author":"RH Symons","year":"1992","unstructured":"Symons, R.H. Small catalytic RNAs. Annu. Rev. Biochem. 61, 641\u2013671 (1992).","journal-title":"Annu. Rev. Biochem."},{"key":"BFnprot2013094_CR75","doi-asserted-by":"crossref","first-page":"4853","DOI":"10.1128\/JVI.65.9.4853-4859.1991","volume":"65","author":"Y Gaudin","year":"1991","unstructured":"Gaudin, Y., Tuffereau, C., Segretain, D., Knossow, M. & Flamand, A. Reversible conformational changes and fusion activity of rabies virus glycoprotein. J. Virol. 65, 4853\u20134859 (1991).","journal-title":"J. Virol."},{"key":"BFnprot2013094_CR76","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1128\/JVI.67.3.1365-1372.1993","volume":"67","author":"Y Gaudin","year":"1993","unstructured":"Gaudin, Y., Ruigrok, R.W., Knossow, M. & Flamand, A. Low-pH conformational changes of rabies virus glycoprotein and their role in membrane fusion. J. Virol. 67, 1365\u20131372 (1993).","journal-title":"J. Virol."}],"container-title":["Nature Protocols"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nprot.2013.094.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nprot.2013.094","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nprot.2013.094.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T20:15:58Z","timestamp":1684440958000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nprot.2013.094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,25]]},"references-count":76,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["BFnprot2013094"],"URL":"https:\/\/doi.org\/10.1038\/nprot.2013.094","relation":{},"ISSN":["1754-2189","1750-2799"],"issn-type":[{"value":"1754-2189","type":"print"},{"value":"1750-2799","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,25]]}}}