{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:18:19Z","timestamp":1791807499058,"version":"4.3.4"},"reference-count":103,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T00:00:00Z","timestamp":1503532800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Rev Cardiol"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1038\/nrcardio.2017.118","type":"journal-article","created":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T10:11:38Z","timestamp":1503569498000},"page":"33-44","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":69,"title":["Hypertension as a cardiovascular risk factor in autoimmune rheumatic diseases"],"prefix":"10.1038","volume":"15","author":[{"given":"Elena","family":"Bartoloni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Alunno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Gerli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,8,24]]},"reference":[{"key":"BFnrcardio2017118_CR1","unstructured":"GBD 2013 Risk Factor Collaborators  et al. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 386, 2287\u20132323 (2015)."},{"key":"BFnrcardio2017118_CR2","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1001\/jamacardio.2016.0218","volume":"1","author":"KN Karmali","year":"2016","unstructured":"Karmali, K. N.  et al. Drugs for primary prevention of atherosclerotic cardiovascular disease: an overview of systematic reviews. JAMA Cardiol. 1, 341\u2013349 (2016).","journal-title":"JAMA Cardiol."},{"issue":"Suppl. 1","key":"BFnrcardio2017118_CR3","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1016\/S0167-5273(15)31026-3","volume":"201","author":"S Bansilal","year":"2015","unstructured":"Bansilal, S., Castellano, J. M. & Fuster, V. Global burden of CVD: focus on secondary prevention of cardiovascular disease. Int. J. Cardiol. 201 (Suppl. 1) S1\u2013S7 (2015).","journal-title":"Int. J. Cardiol."},{"key":"BFnrcardio2017118_CR4","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.phrs.2017.03.017","volume":"120","author":"VC Biancardi","year":"2017","unstructured":"Biancardi, V. C., Bomfim, G. F., Reis, W. L., Al-Gassimi, S. & Nunes, K. P. The interplay between angiotensin II, TLR4 and hypertension. Pharmacol. Res. 120, 88\u201396 (2017).","journal-title":"Pharmacol. Res."},{"key":"BFnrcardio2017118_CR5","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.mcna.2016.08.010","volume":"101","author":"SC Textor","year":"2017","unstructured":"Textor, S. C. Renal arterial disease and hypertension. Med. Clin. North Am. 101, 65\u201379 (2017).","journal-title":"Med. Clin. North Am."},{"key":"BFnrcardio2017118_CR6","doi-asserted-by":"publisher","first-page":"R217","DOI":"10.1152\/ajpregu.00254.2015","volume":"310","author":"RG Evans","year":"2016","unstructured":"Evans, R. G. & Bie, P. Role of the kidney in the pathogenesis of hypertension: 237 time for a neo-Guytonian paradigm or a paradigm shift? Am. J. Physiol. Regul. Integr. Comp. Physiol. 310, R217\u2013R229 (2016).","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"BFnrcardio2017118_CR7","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1152\/physiolgenomics.00098.2016","volume":"49","author":"X Wang","year":"2017","unstructured":"Wang, X. & Garrett, M. R. Nephron number, hypertension, and CKD: physiological and genetic insight from humans and animal models. Physiol. Genomics 49, 180\u2013192 (2017).","journal-title":"Physiol. Genomics"},{"key":"BFnrcardio2017118_CR8","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1038\/nrneph.2017.52","volume":"13","author":"C Zoccalli","year":"2017","unstructured":"Zoccalli, C.  et al. The systemic nature of CKD. Nat. Rev. Nephrol. 13, 344\u2013358 (2017).","journal-title":"Nat. Rev. Nephrol."},{"key":"BFnrcardio2017118_CR9","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1161\/CIRCRESAHA.116.303596","volume":"116","author":"S Laurent","year":"2015","unstructured":"Laurent, S. & Boutouyrie, P. The structural factor of hypertension. Large and small artery alterations. Circ. Res. 116, 1007\u20131021 (2015).","journal-title":"Circ. Res."},{"key":"BFnrcardio2017118_CR10","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.1097\/HJH.0000000000000711","volume":"33","author":"R Kheder-Elfekih","year":"2015","unstructured":"Kheder-Elfekih, R., Yannoutsos, A., Blacher, J., London, G. M. & Safar, M. E. Hypertension and chronic kidney disease: respective contribution of mean and pulse pressure and arterial stiffness. J. Hypertens. 33, 2010\u20132015 (2015).","journal-title":"J. Hypertens."},{"key":"BFnrcardio2017118_CR11","doi-asserted-by":"publisher","first-page":"1402","DOI":"10.1038\/nm.2541","volume":"17","author":"TM Coffman","year":"2011","unstructured":"Coffman, T. M. Under pressure: the search for the essential mechanisms of hypertension. Nat. Med. 17, 1402\u20131409 (2011).","journal-title":"Nat. Med."},{"key":"BFnrcardio2017118_CR12","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.mcna.2016.08.004","volume":"101","author":"R Loperena","year":"2017","unstructured":"Loperena, R. & Harrison, D. G. Oxidative stress and hypertensive diseases. Med. Clin. North Am. 101, 169\u2013193 (2017).","journal-title":"Med. Clin. North Am."},{"key":"BFnrcardio2017118_CR13","doi-asserted-by":"publisher","first-page":"1959","DOI":"10.1093\/ndt\/gfv057","volume":"30","author":"HJ Anders","year":"2015","unstructured":"Anders, H. J., Baumann, M., Tripepi, G. & Mallamaci, F. Immunity in arterial hypertension: associations or causalities? Nephrol. Dial. Transplant. 30, 1959\u20131964 (2015).","journal-title":"Nephrol. Dial. Transplant."},{"key":"BFnrcardio2017118_CR14","first-page":"1","volume":"27","author":"U Wenzel","year":"2015","unstructured":"Wenzel, U.  et al. Immune mechanisms in arterial hypertension. J. Am. Soc. Nephrol. 27, 1\u201310 (2015).","journal-title":"J. Am. Soc. Nephrol."},{"key":"BFnrcardio2017118_CR15","doi-asserted-by":"publisher","first-page":"20303","DOI":"10.1038\/srep20303","volume":"6","author":"FJ Alenghat","year":"2016","unstructured":"Alenghat, F. J. The prevalence of atherosclerosis in those with inflammatory connective tissue disease by race, age, and traditional risk factors. Sci. Rep. 6, 20303 (2016).","journal-title":"Sci. Rep."},{"key":"BFnrcardio2017118_CR16","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1002\/acr.20322","volume":"63","author":"E Bartoloni","year":"2011","unstructured":"Bartoloni, E., Shoenfeld, Y. & Gerli, R. Inflammatory and autoimmune mechanisms in the induction of atherosclerotic damage in systemic rheumatic diseases: two faces of the same coin. Arthritis Care Res. 63, 178\u2013183 (2011).","journal-title":"Arthritis Care Res."},{"key":"BFnrcardio2017118_CR17","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1136\/heartjnl-2015-307838","volume":"102","author":"R Agca","year":"2016","unstructured":"Agca, R., Heslinga, S. C., van Halm, V. P. & Nurmohamed, M. T. Atherosclerotic cardiovascular disease in patients with chronic inflammatory joint disorders. Heart 102, 790\u2013795 (2016).","journal-title":"Heart"},{"key":"BFnrcardio2017118_CR18","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1002\/acr.23014","volume":"69","author":"E Nikiphorou","year":"2017","unstructured":"Nikiphorou, E.  et al. Secular changes in clinical features at presentation of rheumatoid arthritis: Increase in comorbidity but improved inflammatory states. Arthritis Care Res. 69, 21\u201327 (2017).","journal-title":"Arthritis Care Res."},{"key":"BFnrcardio2017118_CR19","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/s10067-014-2802-0","volume":"34","author":"SS Shaharir","year":"2015","unstructured":"Shaharir, S. S., Mustafar, R., Mohd, R., Said, M. & Gafor, H. A. Persistent hypertension in lupus nephritis and the associated risk factors. Clin. Rheumatol. 34, 93\u201397 (2015).","journal-title":"Clin. Rheumatol."},{"key":"BFnrcardio2017118_CR20","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1038\/nrrheum.2011.75","volume":"7","author":"DP Symmons","year":"2011","unstructured":"Symmons, D. P. & Gabriel, S. E. Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE. Nat. Rev. Rheumatol. 7, 399\u2013408 (2011).","journal-title":"Nat. Rev. Rheumatol."},{"key":"BFnrcardio2017118_CR21","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1093\/rheumatology\/kem169","volume":"46","author":"VF Panoulas","year":"2007","unstructured":"Panoulas, V. F.  et al. Prevalence and associations of hypertension and its control in patients with rheumatoid arthritis. Rheumatology 46, 1477\u20131482 (2007).","journal-title":"Rheumatology"},{"key":"BFnrcardio2017118_CR22","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1016\/j.atherosclerosis.2007.01.004","volume":"196","author":"CP Chung","year":"2008","unstructured":"Chung, C. P.  et al. Prevalence of the metabolic syndrome is increased in rheumatoid arthritis and is associated with coronary atherosclerosis. Atherosclerosis 196, 756\u2013763 (2008).","journal-title":"Atherosclerosis"},{"key":"BFnrcardio2017118_CR23","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1196\/annals.1361.069","volume":"1051","author":"R Gerli","year":"2005","unstructured":"Gerli, R.  et al. Early atherosclerosis in rheumatoid arthritis: effects of smoking on thickness of the carotid artery intima media. Ann. NY Acad. Sci. 1051, 281\u2013290 (2005).","journal-title":"Ann. NY Acad. Sci."},{"key":"BFnrcardio2017118_CR24","first-page":"2167","volume":"33","author":"C Han","year":"2006","unstructured":"Han, C.  et al. Cardiovascular disease and risk factors in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. J. Rheumatol. 33, 2167\u20132172 (2006).","journal-title":"J. Rheumatol."},{"key":"BFnrcardio2017118_CR25","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s00296-016-3464-9","volume":"37","author":"R M\u00fcller","year":"2017","unstructured":"M\u00fcller, R.  et al. The metabolic profile in early rheumatoid arthritis: a high prevalence of metabolic obesity. Rheumatol. Int. 37, 21\u201327 (2017).","journal-title":"Rheumatol. Int."},{"key":"BFnrcardio2017118_CR26","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1136\/ard.2006.053488","volume":"66","author":"SA Karvounaris","year":"2007","unstructured":"Karvounaris, S. A.  et al. Metabolic syndrome is common among middle-to-older aged Mediterranean patients with rheumatoid arthritis and correlates with disease activity: a retrospective, cross-sectional, controlled, study. Ann. Rheum. Dis. 66, 28\u201333 (2007).","journal-title":"Ann. Rheum. Dis."},{"key":"BFnrcardio2017118_CR27","doi-asserted-by":"publisher","first-page":"R5","DOI":"10.1186\/ar428","volume":"4","author":"PH Dessein","year":"2002","unstructured":"Dessein, P. H., Stanwix, A. E. & Joffe, B. I. Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis. Arthritis Res. 4, R5 (2002).","journal-title":"Arthritis Res."},{"key":"BFnrcardio2017118_CR28","doi-asserted-by":"publisher","first-page":"249","DOI":"10.7326\/0003-4819-144-4-200602210-00006","volume":"144","author":"MJ Roman","year":"2006","unstructured":"Roman, M. J.  et al. Preclinical carotid atherosclerosis in patients with rheumatoid arthritis. Ann. Intern. Med. 144, 249\u2013256 (2006).","journal-title":"Ann. Intern. Med."},{"key":"BFnrcardio2017118_CR29","doi-asserted-by":"publisher","first-page":"130","DOI":"10.3132\/dvdr.2007.031","volume":"4","author":"G La Montagna","year":"2007","unstructured":"La Montagna, G.  et al. Insulin resistance is an independent risk factor for atherosclerosis in rheumatoid arthritis. Diab. Vasc. Dis. Res. 4, 130\u2013135 (2007).","journal-title":"Diab. Vasc. Dis. Res."},{"key":"BFnrcardio2017118_CR30","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1161\/01.HYP.0000168055.89955.db","volume":"46","author":"MJ Roman","year":"2005","unstructured":"Roman, M. J.  et al. Arterial stiffness in chronic inflammatory diseases. Hypertension 46, 194\u2013199 (2005).","journal-title":"Hypertension"},{"key":"BFnrcardio2017118_CR31","doi-asserted-by":"publisher","first-page":"3444","DOI":"10.1002\/art.20636","volume":"50","author":"DH Solomon","year":"2004","unstructured":"Solomon, D. H., Curhan, G. C., Rimm, E. B., Cannuscio, C. C. & Karlson, E. W. Cardiovascular risk factors in women with and without rheumatoid arthritis. Arthritis Rheum. 50, 3444\u20133449 (2004).","journal-title":"Arthritis Rheum."},{"key":"BFnrcardio2017118_CR32","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.jbspin.2010.07.016","volume":"78","author":"JF Boyer","year":"2011","unstructured":"Boyer, J. F., Gourraud, P., Cantagrel, A., Davignon, J. L. & Constantin, A. Traditional cardiovascular risk factors in rheumatoid arthritis: A meta-analysis. Joint Bone Spine 78, 179\u2013183 (2011).","journal-title":"Joint Bone Spine"},{"key":"BFnrcardio2017118_CR33","doi-asserted-by":"publisher","first-page":"e000267","DOI":"10.1136\/rmdopen-2016-000267","volume":"2","author":"S Siebert","year":"2016","unstructured":"Siebert, S.  et al. Characteristics of rheumatoid arthritis and its association with major comorbid conditions: cross-sectional study of 502 649 UK Biobank participants. RMD Open 2, e000267 (2016).","journal-title":"RMD Open"},{"key":"BFnrcardio2017118_CR34","doi-asserted-by":"publisher","unstructured":"Radner, H., Lesperance, T., Accortt, N. A. & Solomon, D. H. Incidence and prevalence of cardiovascular risk factors among patients with rheumatoid arthritis, psoriasis, or psoriatic arthritis. Arthritis Care Res. \n                    http:\/\/dx.doi.org\/10.1002\/acr.23171\n                    \n                   (2016).","DOI":"10.1002\/acr.23171"},{"key":"BFnrcardio2017118_CR35","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1002\/acr.23094","volume":"69","author":"K Jafri","year":"2017","unstructured":"Jafri, K., Bartels, C., Shin, D., Gelfand, J. & Ogdie, A. Incidence and management of cardiovascular risk factors in psoriatic arthritis and rheumatoid arthritis: A population-based study. Arthritis Care Res. 69, 51\u201357 (2017).","journal-title":"Arthritis Care Res."},{"key":"BFnrcardio2017118_CR36","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1093\/rheumatology\/ken159","volume":"47","author":"VF Panoulas","year":"2008","unstructured":"Panoulas, V. F.  et al. Hypertension in rheumatoid arthritis. Rheumatology 47, 1286\u20131298 (2008).","journal-title":"Rheumatology"},{"key":"BFnrcardio2017118_CR37","doi-asserted-by":"publisher","first-page":"1806","DOI":"10.3899\/jrheum.130394","volume":"40","author":"S Manavathongchai","year":"2013","unstructured":"Manavathongchai, S.  et al. Inflammation and hypertension in rheumatoid arthritis. J. Rheumatol. 40, 1806\u20131811 (2013).","journal-title":"J. Rheumatol."},{"key":"BFnrcardio2017118_CR38","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1136\/annrheumdis-2011-201194","volume":"72","author":"A Jamnitski","year":"2013","unstructured":"Jamnitski, A.  et al. Cardiovascular comorbidities in patients with psoriatic arthritis: a systematic review. Ann. Rheum. Dis. 72, 211\u2013216 (2013).","journal-title":"Ann. Rheum. Dis."},{"key":"BFnrcardio2017118_CR39","doi-asserted-by":"publisher","first-page":"3069","DOI":"10.1007\/s10067-016-3362-2","volume":"35","author":"N Ahmed","year":"2016","unstructured":"Ahmed, N.  et al. Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study. Clin. Rheumatol. 35, 3069\u20133073 (2016).","journal-title":"Clin. Rheumatol."},{"key":"BFnrcardio2017118_CR40","doi-asserted-by":"publisher","first-page":"376","DOI":"10.3899\/jrheum.141359","volume":"43","author":"N Haque","year":"2016","unstructured":"Haque, N., Lories, R. & de Vlam, K. Comorbidities associated with psoriatic arthritis compared with non-psoriatic spondyloarthritis: a cross-sectional study. J. Rheumatol. 43, 376\u2013382 (2016).","journal-title":"J. Rheumatol."},{"key":"BFnrcardio2017118_CR41","first-page":"182","volume":"32","author":"MH Favarato","year":"2014","unstructured":"Favarato, M. H.  et al. Hypertension and diabetes significantly enhance the risk of cardiovascular disease in patients with psoriatic arthritis. Clin. Exp. Rheumatol. 32, 182\u2013187 (2014).","journal-title":"Clin. Exp. Rheumatol."},{"key":"BFnrcardio2017118_CR42","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s00296-016-3487-2","volume":"37","author":"K Yim","year":"2017","unstructured":"Yim, K. & Armstrong, A. W. Updates on cardiovascular comorbidities associated with psoriatic diseases: epidemiology and mechanisms. Rheumatol. Int. 37, 97\u2013105 (2017).","journal-title":"Rheumatol. Int."},{"key":"BFnrcardio2017118_CR43","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1111\/jdv.12071","volume":"28","author":"J Bostoen","year":"2014","unstructured":"Bostoen, J., Van Praet, L., Brochez, L., Mielants, H. & Lambert, J. A cross-sectional study on the prevalence of metabolic syndrome in psoriasis compared to psoriatic arthritis. J. Eur. Acad. Dermatol. Venereol. 28, 507\u2013511 (2014).","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"BFnrcardio2017118_CR44","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.semarthrit.2004.07.010","volume":"34","author":"MJ Peters","year":"2004","unstructured":"Peters, M. J., van der Horst-Bruinsma, I., Dijkmans, B. & Nurmohamed, M. T. Cardiovascular risk profile of patients with spondylarthropathies, particularly ankylosing spondylitis and psoriatic arthritis. Semin. Arthritis Rheum. 34, 585\u2013592 (2004).","journal-title":"Semin. Arthritis Rheum."},{"key":"BFnrcardio2017118_CR45","doi-asserted-by":"publisher","first-page":"3159","DOI":"10.1002\/art.11296","volume":"48","author":"IN Bruce","year":"2003","unstructured":"Bruce, I. N., Urowitz, M. B., Gladman, D. D., Iba\u00f1ez, D. & Steiner, G. Risk factors for coronary heart disease in women with systemic lupus erythematosus: the Toronto Risk Factor Study. Arthritis Rheum. 48, 3159\u20133167 (2003).","journal-title":"Arthritis Rheum."},{"key":"BFnrcardio2017118_CR46","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.3899\/jrheum.101132","volume":"38","author":"JM Sabio","year":"2011","unstructured":"Sabio, J. M.  et al. Prevalence of and factors associated with hypertension in young and old women with systemic lupus erythematosus. J. Rheumatol. 38, 1026\u20131032 (2011).","journal-title":"J. Rheumatol."},{"key":"BFnrcardio2017118_CR47","doi-asserted-by":"publisher","first-page":"1435","DOI":"10.1177\/2047487314546826","volume":"22","author":"F Ballocca","year":"2015","unstructured":"Ballocca, F.  et al. Predictors of cardiovascular events in patients with systemic lupus erythematosus (SLE): a systematic review and meta-analysis. Eur. J. Prev. Cardiol. 22, 1435\u20131441 (2015).","journal-title":"Eur. J. Prev. Cardiol."},{"key":"BFnrcardio2017118_CR48","first-page":"53","volume":"34","author":"JM Sabio","year":"2016","unstructured":"Sabio, J. M.  et al. Cumulated organ damage is associated with arterial stiffness in women with systemic lupus erythematosus irrespective of renal function. Clin. Exp. Rheumatol. 34, 53\u201357 (2016).","journal-title":"Clin. Exp. Rheumatol."},{"key":"BFnrcardio2017118_CR49","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1002\/acr.23015","volume":"69","author":"I R\u00f9a-Figueroa","year":"2017","unstructured":"R\u00f9a-Figueroa, I.  et al. Comorbidities in patients with primary Sj\u00f6gren's syndrome and systemic lupus erythematosus: a comparative registries-based study. Arthritis Care Res. 69, 38\u201345 (2017).","journal-title":"Arthritis Care Res."},{"key":"BFnrcardio2017118_CR50","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1177\/0961203310367504","volume":"19","author":"M P\u00e9rez-De-Lis","year":"2010","unstructured":"P\u00e9rez-De-Lis, M.  et al. Cardiovascular risk factors in primary Sj\u00f6gren's syndrome: a case\u2013control study in 624 patients. Lupus 19, 941\u2013948 (2010).","journal-title":"Lupus"},{"key":"BFnrcardio2017118_CR51","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1002\/acr.22227","volume":"66","author":"M Juarez","year":"2014","unstructured":"Juarez, M.  et al. Cardiovascular risk factors in women with primary Sj\u00f6gren's syndrome: United Kingdom Primary Sj\u00f6gren's Syndrome Registry Results. Arthritis Care Res. 66, 757\u2013764 (2014).","journal-title":"Arthritis Care Res."},{"key":"BFnrcardio2017118_CR52","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1111\/joim.12346","volume":"278","author":"E Bartoloni","year":"2015","unstructured":"Bartoloni, E.  et al. Cardiovascular disease risk burden in primary Sj\u00f6gren's syndrome: results of a population-based multicentre cohort study. J. Intern. Med. 278, 185\u2013192 (2015).","journal-title":"J. Intern. Med."},{"key":"BFnrcardio2017118_CR53","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1007\/s10067-015-3072-1","volume":"35","author":"K Augusto","year":"2016","unstructured":"Augusto, K.  et al. Metabolic syndrome in Sj\u00f6gren's syndrome patients: a relevant concern for clinical monitoring. Clin. Rheumatol. 35, 639\u2013647 (2016).","journal-title":"Clin. Rheumatol."},{"key":"BFnrcardio2017118_CR54","first-page":"8","volume":"3","author":"F Cannarile","year":"2015","unstructured":"Cannarile, F.  et al. Cardiovascular disease in systemic sclerosis. Ann. Transl. Med. 3, 8 (2015).","journal-title":"Ann. Transl. Med."},{"key":"BFnrcardio2017118_CR55","doi-asserted-by":"publisher","first-page":"R54","DOI":"10.1186\/ar4489","volume":"16","author":"M Frerix","year":"2014","unstructured":"Frerix, M., Stegbauer, J., Kreuter, A. & Weiner, S. M. Atherosclerotic plaques occur in absence of intima-media thickening in both systemic sclerosis and systemic lupus erythematosus: a duplexsonography study of carotid and femoral arteries and follow-up for cardiovascular events. Arthritis Res. Ther. 16, R54 (2014).","journal-title":"Arthritis Res. Ther."},{"key":"BFnrcardio2017118_CR56","doi-asserted-by":"publisher","first-page":"1538","DOI":"10.1002\/acr.22852","volume":"68","author":"G Ozen","year":"2016","unstructured":"Ozen, G.  et al. Subclinical atherosclerosis in systemic sclerosis: not less frequent than rheumatoid arthritis and not detected with cardiovascular risk indices. Arthritis Care Res. 68, 1538\u20131546 (2016).","journal-title":"Arthritis Care Res."},{"key":"BFnrcardio2017118_CR57","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1152\/ajpheart.00759.2016","volume":"312","author":"U Wenze","year":"2017","unstructured":"Wenze, U., Bode, M., K\u00f6hl, J. & Ehmke, H. A pathogenic role of complement in arterial hypertension and hypertensive end organ damage. Am. J. Physiol. Heart Circ. Physiol. 312, 349\u2013354 (2017).","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"BFnrcardio2017118_CR58","doi-asserted-by":"publisher","first-page":"F141","DOI":"10.1152\/ajprenal.00465.2016","volume":"313","author":"AE Norlander","year":"2017","unstructured":"Norlander, A. E. & Madhur, M. S. Inflammatory cytokines regulate renal sodium transporters: how, where, and why? Am. J. Physiol. Renal Physiol. 313, F141\u2013F144 (2017).","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"BFnrcardio2017118_CR59","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1161\/HYPERTENSIONAHA.114.04006","volume":"64","author":"KW Mathis","year":"2014","unstructured":"Mathis, K. W.  et al. Preventing autoimmunity protects again the development of hypertension and renal injury. Hypertension 64, 792\u2013800 (2014).","journal-title":"Hypertension"},{"key":"BFnrcardio2017118_CR60","doi-asserted-by":"publisher","first-page":"e005394","DOI":"10.1161\/JAHA.116.005394","volume":"6","author":"EB Taylor","year":"2017","unstructured":"Taylor, E. B. & Ryan, M. J. Immunosuppression with mycophenolate mofetil attenuates hypertension in an experimental model of autoimmune disease. J. Am. Heart Assoc. 6, e005394 (2017).","journal-title":"J. Am. Heart Assoc."},{"key":"BFnrcardio2017118_CR61","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1177\/1753944716637807","volume":"11","author":"EB Taylor","year":"2016","unstructured":"Taylor, E. B. & Ryan, M. J. Understanding mechanisms of hypertension in systemic lupus erythematosus. Ther. Adv. Cardiovasc. Dis. 11, 20\u201332 (2016).","journal-title":"Ther. Adv. Cardiovasc. Dis."},{"key":"BFnrcardio2017118_CR62","doi-asserted-by":"publisher","first-page":"457","DOI":"10.3109\/07853890.2015.1068950","volume":"47","author":"P Ambrosino","year":"2015","unstructured":"Ambrosino, P.  et al. Non-invasive assessment of arterial stiffness in patients with rheumatoid arthritis: A systematic review and meta-analysis of literature studies. Ann. Med. 47, 457\u2013467 (2015).","journal-title":"Ann. Med."},{"key":"BFnrcardio2017118_CR63","doi-asserted-by":"publisher","first-page":"e94511","DOI":"10.1371\/journal.pone.0094511","volume":"9","author":"K Sacre","year":"2014","unstructured":"Sacre, K.  et al. Increased arterial stiffness in systemic lupus erythematosus (SLE) patients at low risk for cardiovascular disease: a cross-sectional controlled study. PLoS ONE 9, e94511 (2014).","journal-title":"PLoS ONE"},{"key":"BFnrcardio2017118_CR64","doi-asserted-by":"publisher","first-page":"1504","DOI":"10.1161\/HYPERTENSIONAHA.116.08345","volume":"68","author":"E Bartoloni","year":"2016","unstructured":"Bartoloni, E.  et al. Central hemodynamics and arterial stiffness in systemic sclerosis. Hypertension 68, 1504\u20131511 (2016).","journal-title":"Hypertension"},{"key":"BFnrcardio2017118_CR65","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1161\/01.HYP.37.5.1236","volume":"37","author":"S Laurent","year":"2011","unstructured":"Laurent, S.  et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 37, 1236\u20131241 (2011).","journal-title":"Hypertension"},{"key":"BFnrcardio2017118_CR66","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1586\/1744666X.3.4.531","volume":"3","author":"E Bartoloni Bocci","year":"2007","unstructured":"Bartoloni Bocci, E.  et al. Accelerated atherosclerosis in systemic lupus erythematosus and other connective tissue diseases. Expert Rev. Clin. Immunol. 3, 531\u2013541 (2007).","journal-title":"Expert Rev. Clin. Immunol."},{"key":"BFnrcardio2017118_CR67","doi-asserted-by":"publisher","first-page":"3890","DOI":"10.1002\/art.21475","volume":"52","author":"G Vaudo","year":"2005","unstructured":"Vaudo, G.  et al. Precocious intima-media thickening in patients with primary Sj\u00f6gren's syndrome. Arthritis Rheum. 52, 3890\u20133897 (2005).","journal-title":"Arthritis Rheum."},{"key":"BFnrcardio2017118_CR68","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1002\/acr.20117","volume":"62","author":"R Gerli","year":"2010","unstructured":"Gerli, R.  et al. Functional impairment of the arterial wall in primary Sj\u00f6gren's syndrome: combined action of immunologic and inflammatory factors. Arthritis Care Res. 62, 712\u2013718 (2010).","journal-title":"Arthritis Care Res."},{"key":"BFnrcardio2017118_CR69","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1093\/rheumatology\/keu320","volume":"54","author":"E Bartoloni","year":"2015","unstructured":"Bartoloni, E.  et al. Characterization of circulating endothelial microparticles and endothelial progenitor cells in primary Sj\u00f6gren's syndrome: new markers of chronic endothelial damage? Rheumatology 54, 536\u2013544 (2015).","journal-title":"Rheumatology"},{"key":"BFnrcardio2017118_CR70","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/s11906-015-0596-3","volume":"17","author":"E Gkaliagkousi","year":"2015","unstructured":"Gkaliagkousi, E., Gavriilaki, E., Triantafyllou, A. & Douma, S. Clinical significance of endothelial dysfunction in essential hypertension. Curr. Hypertens. Rep. 17, 85 (2015).","journal-title":"Curr. Hypertens. Rep."},{"key":"BFnrcardio2017118_CR71","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1007\/s11906-003-0007-z","volume":"5","author":"C van Guldener","year":"2003","unstructured":"van Guldener, C., Nanayakkara, P. W. & Stehouwer, C. D. Homocysteine and blood pressure. Curr. Hypertens. Rep. 5, 26\u201331 (2003).","journal-title":"Curr. Hypertens. Rep."},{"key":"BFnrcardio2017118_CR72","doi-asserted-by":"publisher","first-page":"3238","DOI":"10.1161\/CIRCULATIONAHA.107.741645","volume":"117","author":"KK Koh","year":"2008","unstructured":"Koh, K. K., Park, S. M. & Quon, M. J. Leptin and cardiovascular disease: response to therapeutic interventions. Circulation 117, 3238\u20133249 (2008).","journal-title":"Circulation"},{"key":"BFnrcardio2017118_CR73","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1007\/s12170-017-0537-6","volume":"11","author":"R Nosalski","year":"2017","unstructured":"Nosalski, R., McGinnigle, E., Siedlinski, M. & Guzik, T. J. Novel immune mechanisms in hypertension and cardiovascular risk. Curr. Cardiovasc. Risk Rep. 11, 12 (2017).","journal-title":"Curr. Cardiovasc. Risk Rep."},{"key":"BFnrcardio2017118_CR74","doi-asserted-by":"publisher","unstructured":"Nosalski, R. & Guzik, T. J. Perivascular adipose tissue inflammation in vascular disease. Br. J. Pharmacol. \n                    http:\/\/dx.doi.org\/10.1111\/bph.13705\n                    \n                   (2017).","DOI":"10.1111\/bph.13705"},{"key":"BFnrcardio2017118_CR75","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1097\/CRD.0b013e31821ddcf4","volume":"19","author":"S Snowden","year":"2011","unstructured":"Snowden, S. & Nelson, R. The effects of nonsteroidal anti-inflammatory drugs on blood pressure in hypertensive patients. Cardiol. Rev. 19, 184\u2013191 (2011).","journal-title":"Cardiol. Rev."},{"key":"BFnrcardio2017118_CR76","doi-asserted-by":"publisher","first-page":"1759","DOI":"10.1016\/j.amjcard.2010.03.001","volume":"105","author":"VE Friedewald","year":"2010","unstructured":"Friedewald, V. E.  et al. The editor's roundtable: effect of nonsteroidal anti-inflammatory drugs on blood pressure. Am. J. Cardiol. 105, 1759\u20131767 (2010).","journal-title":"Am. J. Cardiol."},{"key":"BFnrcardio2017118_CR77","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/0014-2999(90)90105-F","volume":"27","author":"GF Seng","year":"1990","unstructured":"Seng, G. F., Benensohn, J. & Bayer, B. M. Changes in T and B lymphocyte proliferative responses in adjuvant-arthritic rats: antagonism by indomethacin. Eur. J. Pharmacol. 27, 267\u2013273 (1990).","journal-title":"Eur. J. Pharmacol."},{"key":"BFnrcardio2017118_CR78","doi-asserted-by":"publisher","first-page":"1758","DOI":"10.3899\/jrheum.120192","volume":"39","author":"E Bartoloni","year":"2012","unstructured":"Bartoloni, E., Alunno, A., Santoboni, G. & Gerli, R. Beneficial cardiovascular effects of low-dose glucocorticoid therapy in inflammatory rheumatic diseases. J. Rheumatol. 39, 1758\u20131760 (2012).","journal-title":"J. Rheumatol."},{"key":"BFnrcardio2017118_CR79","doi-asserted-by":"publisher","first-page":"S218","DOI":"10.1681\/ASN.2006080918","volume":"17","author":"J Herrera","year":"2006","unstructured":"Herrera, J., Ferrebuz, A., MacGregor, E. G. & Rodriguez-Iturbe, B. Mycophenolate mofetil treatment improves hypertension in patients with psoriasis and rheumatoid arthritis. J. Am. Soc. Nephrol. 17, S218\u2013S225 (2006).","journal-title":"J. Am. Soc. Nephrol."},{"key":"BFnrcardio2017118_CR80","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1161\/HYPERTENSIONAHA.110.157685","volume":"56","author":"M Venegas-Pont","year":"2010","unstructured":"Venegas-Pont, M.  et al. The TNF-\u03b1 antagonist etanercept decreases blood pressure and protects the kidney in a mouse model of systemic lupus erythematosus. Hypertension 56, 643\u2013649 (2010).","journal-title":"Hypertension"},{"key":"BFnrcardio2017118_CR81","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1038\/jhh.2013.80","volume":"28","author":"S Yoshida","year":"2014","unstructured":"Yoshida, S.  et al. Infliximab, a TNF-a inhibitor, reduces 24- h ambulatory blood pressure in rheumatoid arthritis patients. J. Hum. Hypertens. 28, 165\u2013169 (2014).","journal-title":"J. Hum. Hypertens."},{"key":"BFnrcardio2017118_CR82","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1038\/jhh.2011.36","volume":"25","author":"A Sandoo","year":"2011","unstructured":"Sandoo, A.  et al. Anti-TNF\u03b1 therapy may lead to blood pressure reductions through improved endothelium-dependent microvascular function in patients with rheumatoid arthritis. J. Hum. Hypertens. 25, 699\u2013702 (2011).","journal-title":"J. Hum. Hypertens."},{"key":"BFnrcardio2017118_CR83","doi-asserted-by":"publisher","first-page":"1342","DOI":"10.1136\/ard.2009.124180","volume":"69","author":"N Klarenbeek","year":"2010","unstructured":"Klarenbeek, N.  et al. Blood pressure changes in patients with recent-onset rheumatoid arthritis treated with four different treatment strategies: a post hoc analysis from the BeSt trial. Ann. Rheum. Dis. 69, 1342\u20131345 (2010).","journal-title":"Ann. Rheum. Dis."},{"key":"BFnrcardio2017118_CR84","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1097\/EDE.0000000000000446","volume":"27","author":"R Desai","year":"2016","unstructured":"Desai, R.  et al. Tumor necrosis factor-\u03b1 inhibitor use and the risk of incident hypertension in patients with rheumatoid arthritis. Epidemiology 27, 414\u2013422 (2016).","journal-title":"Epidemiology"},{"key":"BFnrcardio2017118_CR85","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.1136\/annrheumdis-2012-202007","volume":"72","author":"A Man","year":"2013","unstructured":"Man, A.  et al. The risk of cardiovascular disease in systemic sclerosis: a population-based cohort study. Ann. Rheum. Dis. 72, 1188\u20131193 (2013).","journal-title":"Ann. Rheum. Dis."},{"key":"BFnrcardio2017118_CR86","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1136\/ard.2008.089862","volume":"68","author":"BJ Radovits","year":"2009","unstructured":"Radovits, B. J.  et al. Disease activity as a risk factor for myocardial infarction in rheumatoid arthritis. Ann. Rheum. Dis. 68, 1271\u20131276 (2009).","journal-title":"Ann. Rheum. Dis."},{"key":"BFnrcardio2017118_CR87","doi-asserted-by":"publisher","first-page":"131","DOI":"10.3109\/03009742.2012.723747","volume":"42","author":"R Koivuniemi","year":"2013","unstructured":"Koivuniemi, R., Paimela, L., Suomalainen, R. & Leirisalo-Repo, M. Cardiovascular diseases in patients with rheumatoid arthritis. Scand. J. Rheumatol. 42, 131\u2013135 (2013).","journal-title":"Scand. J. Rheumatol."},{"key":"BFnrcardio2017118_CR88","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.jbspin.2006.10.001","volume":"74","author":"N Assous","year":"2007","unstructured":"Assous, N., Touze, E., Meune, C., Kahan, A. & Allanore, Y. Cardiovascular disease in rheumatoid arthritis: single-center hospital-based cohort study in France. Joint Bone Spine 74, 66\u201372 (2007).","journal-title":"Joint Bone Spine"},{"key":"BFnrcardio2017118_CR89","doi-asserted-by":"publisher","first-page":"R30","DOI":"10.1186\/ar2383","volume":"10","author":"A Naranjo","year":"2008","unstructured":"Naranjo, A.  et al. Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study. Arthritis Res. Ther. 10, R30 (2008).","journal-title":"Arthritis Res. Ther."},{"key":"BFnrcardio2017118_CR90","doi-asserted-by":"publisher","first-page":"236","DOI":"10.3899\/jrheum.100564","volume":"38","author":"J Serelis","year":"2011","unstructured":"Serelis, J., Panagiotakos, D. B., Mavrommati, M. & Skopouli, F. N. Cardiovascular disease is related to hypertension in patients with rheumatoid arthritis: a greek cohort study. J. Rheumatol. 38, 236\u2013241 (2011).","journal-title":"J. Rheumatol."},{"key":"BFnrcardio2017118_CR91","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1136\/ard.2006.059980","volume":"67","author":"A Gonzalez","year":"2008","unstructured":"Gonzalez, A.  et al. Do cardiovascular risk factors confer the same risk for cardiovascular outcomes in rheumatoid arthritis patients as in non rheumatoid arthritis patients? Ann. Rheum. Dis. 67, 64\u201369 (2008).","journal-title":"Ann. Rheum. Dis."},{"key":"BFnrcardio2017118_CR92","doi-asserted-by":"publisher","first-page":"R131","DOI":"10.1186\/ar3442","volume":"13","author":"L Innala","year":"2011","unstructured":"Innala, L.  et al. Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study. Arthritis Res. Ther. 13, R131 (2011).","journal-title":"Arthritis Res. Ther."},{"key":"BFnrcardio2017118_CR93","doi-asserted-by":"publisher","first-page":"e0117952","DOI":"10.1371\/journal.pone.0117952","volume":"10","author":"L Baghdadi","year":"2015","unstructured":"Baghdadi, L., Woodman, R., Shanahan, E. & Mangoni, A. The impact of traditional cardiovascular risk factors on cardiovascular outcomes in patients with rheumatoid arthritis: a systematic review and meta-analysis. PLoS ONE 10, e0117952 (2015).","journal-title":"PLoS ONE"},{"key":"BFnrcardio2017118_CR94","doi-asserted-by":"publisher","first-page":"e0170108","DOI":"10.1371\/journal.pone.0170108","volume":"12","author":"P Ruscitti","year":"2017","unstructured":"Ruscitti, P.  et al. Increased cardiovascular events and subclinical atherosclerosis in rheumatoid arthritis patients: 1 year prospective single Centre study. PLoS ONE 12, e0170108 (2017).","journal-title":"PLoS ONE"},{"key":"BFnrcardio2017118_CR95","doi-asserted-by":"publisher","first-page":"298","DOI":"10.3109\/08037051.2016.1172867","volume":"25","author":"H Midtb\u00f8","year":"2016","unstructured":"Midtb\u00f8, H.  et al. The association of hypertension with asymptomatic cardiovascular organ damage in rheumatoid arthritis. Blood Press. 25, 298\u2013304 (2016).","journal-title":"Blood Press."},{"key":"BFnrcardio2017118_CR96","doi-asserted-by":"publisher","first-page":"e1183","DOI":"10.1097\/MD.0000000000001183","volume":"94","author":"A Fern\u00e0ndez-Nebro","year":"2015","unstructured":"Fern\u00e0ndez-Nebro, A.  et al. Cardiovascular events in systemic lupus erythematosus. A nationwide study in Spain from the RELESSER Registry. Medicine 94, e1183 (2015).","journal-title":"Medicine"},{"key":"BFnrcardio2017118_CR97","doi-asserted-by":"publisher","first-page":"e000143","DOI":"10.1136\/lupus-2015-000143","volume":"3","author":"M Urowitz","year":"2016","unstructured":"Urowitz, M.  et al. Cardiovascular events prior to or early after diagnosis of systemic lupus erythematosus in the systemic lupus international collaborating clinics cohort. Lupus Sci. Med. 3, e000143 (2016).","journal-title":"Lupus Sci. Med."},{"key":"BFnrcardio2017118_CR98","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s00296-016-3632-y","volume":"37","author":"P Ostojic","year":"2017","unstructured":"Ostojic, P. & Stojanovski, N. Arterial hypertension treated with angiotensin converting enzyme inhibitors and glucocorticoids are independent risk factors associated with decreased glomerular filtration rate in systemic sclerosis. Rheumatol. Int. 37, 363\u2013368 (2017).","journal-title":"Rheumatol. Int."},{"key":"BFnrcardio2017118_CR99","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.1093\/rheumatology\/kew210","volume":"55","author":"MJ Cook","year":"2016","unstructured":"Cook, M. J.  et al. Predictors and outcomes of sustained, intermittent or never achieving remission in patients with recent onset inflammatory polyarthritis: results from the Norfolk Arthritis Register. Rheumatology 55, 1601\u20131609 (2016).","journal-title":"Rheumatology"},{"key":"BFnrcardio2017118_CR100","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1002\/acr.22740","volume":"5","author":"J An","year":"2016","unstructured":"An, J.  et al. Traditional cardiovascular disease risk factor management in rheumatoid arthritis compared to matched nonrheumatoid arthritis in a US managed care setting. Arthritis Care Res. 5, 629\u2013637 (2016).","journal-title":"Arthritis Care Res."},{"key":"BFnrcardio2017118_CR101","first-page":"714","volume":"30","author":"G Singh","year":"2003","unstructured":"Singh, G.  et al. Consequences of increased systolic blood pressure in patients with osteoarthritis and rheumatoid arthritis. J. Rheumatol. 30, 714\u2013719 (2003).","journal-title":"J. Rheumatol."},{"key":"BFnrcardio2017118_CR102","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1136\/annrheumdis-2016-209775","volume":"76","author":"R Agca","year":"2017","unstructured":"Agca, R.  et al. EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015\/2016 update. Ann. Rheum. Dis. 76, 17\u201328 (2017).","journal-title":"Ann. Rheum. Dis."},{"key":"BFnrcardio2017118_CR103","doi-asserted-by":"publisher","first-page":"2262","DOI":"10.1161\/CIRCULATIONAHA.107.734384","volume":"117","author":"A Flammer","year":"2008","unstructured":"Flammer, A.  et al. Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritis. Circulation 117, 2262\u20132269 (2008).","journal-title":"Circulation"}],"container-title":["Nature Reviews Cardiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nrcardio.2017.118.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrcardio.2017.118","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/nrcardio.2017.118","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/nrcardio.2017.118.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T03:59:38Z","timestamp":1684468778000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nrcardio.2017.118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,24]]},"references-count":103,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["BFnrcardio2017118"],"URL":"https:\/\/doi.org\/10.1038\/nrcardio.2017.118","relation":{},"ISSN":["1759-5002","1759-5010"],"issn-type":[{"value":"1759-5002","type":"print"},{"value":"1759-5010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,24]]},"assertion":[{"value":"24 August 2017","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}