{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T13:06:01Z","timestamp":1777467961859,"version":"3.51.4"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Rev Endocrinol"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1038\/nrendo.2009.220","type":"journal-article","created":{"date-parts":[[2009,11,19]],"date-time":"2009-11-19T21:47:19Z","timestamp":1258667239000},"page":"648-649","source":"Crossref","is-referenced-by-count":5,"title":["Where is the SPARC in adipose-tissue inflammation?"],"prefix":"10.1038","volume":"5","author":[{"given":"Mourad","family":"Na\u00efmi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Van Obberghen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BFnrendo2009220_CR1","doi-asserted-by":"publisher","first-page":"22231","DOI":"10.1074\/jbc.M010634200","volume":"276","author":"S Tartare-Deckert","year":"2001","unstructured":"Tartare-Deckert, S., Chavey, C., Monthouel, M. N., Gautier, N. & Van Obberghen, E. The matricellular protein SPARC\/osteonectin as a newly identified factor up-regulated in obesity. J. Biol. Chem. 276, 22231\u201322237 (2001).","journal-title":"J. Biol. Chem."},{"key":"BFnrendo2009220_CR2","doi-asserted-by":"publisher","first-page":"6045","DOI":"10.1073\/pnas.1030790100","volume":"100","author":"AD Bradshaw","year":"2003","unstructured":"Bradshaw, A. D., Graves, D. C., Motamed, K. & Sage, E. H. SPARC-null mice exhibit increased adiposity without significant differences in overall body weight. Proc. Natl Acad. Sci. USA 100, 6045\u20136050 (2003).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrendo2009220_CR3","doi-asserted-by":"publisher","first-page":"1780","DOI":"10.2337\/db09-0211","volume":"58","author":"K Kos","year":"2009","unstructured":"Kos, K.  et al. Regulation of the fibrosis and angiogenesis promoter SPARC\/osteonectin in human adipose tissue by weight change, leptin, insulin, and glucose. Diabetes 58, 1780\u20131788 (2009).","journal-title":"Diabetes"},{"key":"BFnrendo2009220_CR4","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1074\/jbc.M808285200","volume":"284","author":"J Nie","year":"2009","unstructured":"Nie, J. & Sage, E. H. SPARC inhibits adipogenesis by its enhancement of beta-catenin signaling. J. Biol. Chem. 284, 1279\u20131290 (2009).","journal-title":"J. Biol. Chem."},{"key":"BFnrendo2009220_CR5","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1126\/science.289.5481.950","volume":"289","author":"SE Ross","year":"2000","unstructured":"Ross, S. E.  et al. Inhibition of adipogenesis by Wnt signaling. Science 289, 950\u2013953 (2000).","journal-title":"Science"},{"key":"BFnrendo2009220_CR6","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1056\/NEJMra025261","volume":"350","author":"A Garg","year":"2004","unstructured":"Garg, A. Acquired and inherited lipodystrophies. N. Engl. J. Med. 350, 1220\u20131234 (2004).","journal-title":"N. Engl. J. Med."},{"key":"BFnrendo2009220_CR7","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1128\/MCB.01300-08","volume":"29","author":"T Khan","year":"2009","unstructured":"Khan, T.  et al. Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI. Mol. Cell Biol. 29, 1575\u20131591 (2009).","journal-title":"Mol. Cell Biol."},{"key":"BFnrendo2009220_CR8","doi-asserted-by":"publisher","first-page":"2621","DOI":"10.1172\/JCI31021","volume":"117","author":"JY Kim","year":"2007","unstructured":"Kim, J. Y.  et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J. Clin. Invest. 117, 2621\u20132637 (2007).","journal-title":"J. Clin. Invest."},{"key":"BFnrendo2009220_CR9","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1038\/nm0809-846","volume":"15","author":"CN Lumeng","year":"2009","unstructured":"Lumeng, C. N., Maillard, I. & Saltiel, A. R. T-ing up inflammation in fat. Nat. Med. 15, 846\u2013847 (2009).","journal-title":"Nat. Med."},{"key":"BFnrendo2009220_CR10","doi-asserted-by":"publisher","first-page":"5825","DOI":"10.4049\/jimmunol.176.10.5825","volume":"176","author":"J Kzhyshkowska","year":"2006","unstructured":"Kzhyshkowska, J.  et al. Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC. J. Immunol. 176, 5825\u20135832 (2006).","journal-title":"J. Immunol."}],"container-title":["Nature Reviews Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nrendo.2009.220.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrendo.2009.220","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrendo.2009.220.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T03:32:31Z","timestamp":1684467151000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nrendo.2009.220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":10,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["BFnrendo2009220"],"URL":"https:\/\/doi.org\/10.1038\/nrendo.2009.220","relation":{},"ISSN":["1759-5029","1759-5037"],"issn-type":[{"value":"1759-5029","type":"print"},{"value":"1759-5037","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}