{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:11:26Z","timestamp":1761513086443,"version":"3.37.3"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2012,1,31]],"date-time":"2012-01-31T00:00:00Z","timestamp":1327968000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Rev Endocrinol"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1038\/nrendo.2012.9","type":"journal-article","created":{"date-parts":[[2012,1,31]],"date-time":"2012-01-31T10:40:16Z","timestamp":1328006416000},"page":"197-198","source":"Crossref","is-referenced-by-count":9,"title":["Patching up a better pill for GH-deficient women"],"prefix":"10.1038","volume":"8","author":[{"given":"Vita","family":"Birzniece","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken K. Y.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,1,31]]},"reference":[{"key":"BFnrendo20129_CR1","doi-asserted-by":"publisher","unstructured":"Isotton, A. L., Wender, M. C., Casagrande, A., Rollin, G. & Czepielewski, M. A. Effects of oral and transdermal estrogen on IGF-1, IGFBP-3, IGFBP-1, serum lipids and glucose in patients with hypopituitarism during growth hormone treatment: a randomized study. Eur. J. Endocrinol. \n                    http:\/\/dx.doi.org\/10.1530\/EJE-11-0560\n                    \n                  .","DOI":"10.1530\/EJE-11-0560"},{"key":"BFnrendo20129_CR2","doi-asserted-by":"publisher","unstructured":"Phelan, N., Conway, S. H., Llahana, S. & Conway, G. S. Quantification of the adverse effect of ethinylestradiol containing oral contraceptive pills when used in conjunction with growth hormone replacement in routine practice. Clin. Endocrinol. (Oxf.) \n                    http:\/\/dx.doi.org\/10.1111\/J.1365\u201322652011.04277.x\n                    \n                  .","DOI":"10.1111\/J.1365-22652011.04277.x"},{"key":"BFnrendo20129_CR3","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1056\/NEJM198606193142505","volume":"314","author":"RJ Chetkowski","year":"1986","unstructured":"Chetkowski, R. J.  et al. Biologic effects of transdermal estradiol. N. Engl. J. Med. 314, 1615\u20131620 (1986).","journal-title":"N. Engl. J. Med."},{"key":"BFnrendo20129_CR4","first-page":"2250","volume":"81","author":"KE Friend","year":"1996","unstructured":"Friend, K. E., Hartman, M. L., Pezzoli, S. S., Clasey, J. L. & Thorner, M. O. Both oral and transdermal estrogen increase growth hormone release in postmenopausal women\u2014a clinical research center study. J. Clin. Endocrinol. Metab. 81, 2250\u20132256 (1996).","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BFnrendo20129_CR5","doi-asserted-by":"crossref","first-page":"E1191","DOI":"10.1152\/ajpendo.2001.281.6.E1191","volume":"281","author":"T Wolthers","year":"2001","unstructured":"Wolthers, T., Hoffman, D. M., Nugent, A. G., Duncan, M. M. & Ho, K. K. Y. Oral estrogen antagonizes the metabolic actions of growth hormone in growth hormone-deficient women. Am. J. Physiol. Endocrinol. Metab. 281, E1191\u2013E1196 (2001).","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"BFnrendo20129_CR6","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1210\/er.2003-0035","volume":"25","author":"KC Leung","year":"2004","unstructured":"Leung, K. C., Johannsson, G., Leong, G. M. & Ho, K. K. Estrogen regulation of growth hormone action. Endocr. Rev. 25, 693\u2013721 (2004).","journal-title":"Endocr. Rev."},{"key":"BFnrendo20129_CR7","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/0002-9378(82)90218-6","volume":"144","author":"CA Mashchak","year":"1982","unstructured":"Mashchak, C. A.  et al. Comparison of pharmacodynamic properties of various estrogen formulations. Am. J. Obstet. Gynecol. 144, 511\u2013518 (1982).","journal-title":"Am. J. Obstet. Gynecol."},{"key":"BFnrendo20129_CR8","doi-asserted-by":"crossref","first-page":"5964","DOI":"10.1210\/jc.2005-1207","volume":"90","author":"PM Mah","year":"2005","unstructured":"Mah, P. M.  et al. Estrogen replacement in women of fertile years with hypopituitarism. J. Clin. Endocrinol. Metab. 90, 5964\u20135969 (2005).","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BFnrendo20129_CR9","doi-asserted-by":"crossref","first-page":"3897","DOI":"10.1210\/jc.2005-0173","volume":"90","author":"J Gibney","year":"2005","unstructured":"Gibney, J., Johannsson, G., Leung, K. C. & Ho, K. K. Comparison of the metabolic effects of raloxifene and oral estrogen in postmenopausal and growth hormone-deficient women. J. Clin. Endocrinol. Metab. 90, 3897\u20133903 (2005).","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"BFnrendo20129_CR10","doi-asserted-by":"publisher","unstructured":"Birzniece, V.  et al. Differential effects of raloxifene and estrogen on body composition in growth hormone-replaced hypopituitary women. J. Clin. Endocrinol. Metab. \n                    http:\/\/dx.doi.org\/10.1210\/jc.2011\u20132837\n                    \n                  .","DOI":"10.1210\/jc.2011-2837"}],"container-title":["Nature Reviews Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nrendo.2012.9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrendo.2012.9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrendo.2012.9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T03:40:27Z","timestamp":1684467627000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nrendo.2012.9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,31]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["BFnrendo20129"],"URL":"https:\/\/doi.org\/10.1038\/nrendo.2012.9","relation":{},"ISSN":["1759-5029","1759-5037"],"issn-type":[{"type":"print","value":"1759-5029"},{"type":"electronic","value":"1759-5037"}],"subject":[],"published":{"date-parts":[[2012,1,31]]}}}