{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T18:24:52Z","timestamp":1790360692495,"version":"4.1.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Rev Microbiol"],"published-print":{"date-parts":[[2007,7]]},"DOI":"10.1038\/nrmicro1703","type":"journal-article","created":{"date-parts":[[2007,6,16]],"date-time":"2007-06-16T12:50:52Z","timestamp":1181998252000},"page":"484-487","source":"Crossref","is-referenced-by-count":72,"title":["Tuberculosis vaccines \u2014 an update"],"prefix":"10.1038","volume":"5","author":[{"given":"Peter","family":"Andersen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"BFnrmicro1703_CR1","unstructured":"WHO. Global tuberculosis control \u2014 surveillance, planning, financing. [online] (2004)."},{"key":"BFnrmicro1703_CR2","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1038\/nrmicro1211","volume":"3","author":"P Andersen","year":"2005","unstructured":"Andersen, P. & Doherty, T. M. The success and failure of BCG \u2014 implications for a novel tuberculosis vaccine. Nature Rev. Microbiol. 3, 656\u2013662 (2005).","journal-title":"Nature Rev. Microbiol."},{"key":"BFnrmicro1703_CR3","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1016\/S0140-6736(06)68384-0","volume":"367","author":"C Dye","year":"2006","unstructured":"Dye, C. Global epidemiology of tuberculosis. Lancet 367, 938\u2013940 (2006).","journal-title":"Lancet"},{"key":"BFnrmicro1703_CR4","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1016\/j.it.2005.09.012","volume":"26","author":"SH Kaufmann","year":"2005","unstructured":"Kaufmann, S. H. Recent findings in immunology give tuberculosis vaccines a new boost. Trends Immunol. 26, 660\u2013667 (2005).","journal-title":"Trends Immunol."},{"key":"BFnrmicro1703_CR5","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1615\/CritRevImmunol.v26.i4.30","volume":"26","author":"JS Woodworth","year":"2006","unstructured":"Woodworth, J. S. & Behar, S. M. Mycobacterium tuberculosis-specific CD8+ T cells and their role in immunity. Crit. Rev. Immunol. 26, 317\u2013352 (2006).","journal-title":"Crit. Rev. Immunol."},{"key":"BFnrmicro1703_CR6","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.tim.2006.11.008","volume":"15","author":"P Andersen","year":"2007","unstructured":"Andersen, P. Vaccine strategies against latent tuberculosis infection. Trends Microbiol. 15, 7\u201313 (2007).","journal-title":"Trends Microbiol."},{"key":"BFnrmicro1703_CR7","doi-asserted-by":"publisher","first-page":"3753","DOI":"10.1016\/j.vaccine.2005.03.001","volume":"23","author":"AT Kamath","year":"2005","unstructured":"Kamath, A. T. et al. New live mycobacterial vaccines: the Geneva consensus on essential steps towards clinical development. Vaccine 23, 3753\u20133761 (2005).","journal-title":"Vaccine"},{"key":"BFnrmicro1703_CR8","doi-asserted-by":"publisher","first-page":"1672","DOI":"10.1128\/IAI.71.4.1672-1679.2003","volume":"71","author":"MA Horwitz","year":"2003","unstructured":"Horwitz, M. A. & Harth, G. A new vaccine against tuberculosis affords greater survival after challenge than the current vaccine in the guinea pig model of pulmonary tuberculosis. Infect. Immun. 71, 1672\u20131679 (2003).","journal-title":"Infect. Immun."},{"key":"BFnrmicro1703_CR9","doi-asserted-by":"publisher","first-page":"2472","DOI":"10.1172\/JCI24617","volume":"115","author":"L Grode","year":"2005","unstructured":"Grode, L. et al. Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette\u2013Guerin mutants that secrete listeriolysin. J. Clin. Invest. 115, 2472\u20132479 (2005).","journal-title":"J. Clin. Invest."},{"key":"BFnrmicro1703_CR10","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.immuni.2005.12.001","volume":"24","author":"F Winau","year":"2006","unstructured":"Winau, F. et al. Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis. Immunity 24, 105\u2013117 (2006).","journal-title":"Immunity"},{"key":"BFnrmicro1703_CR11","doi-asserted-by":"publisher","first-page":"5452","DOI":"10.1016\/j.vaccine.2006.03.072","volume":"24","author":"EM Agger","year":"2006","unstructured":"Agger, E. M. et al. Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31. Vaccine 24, 5452\u20135460 (2006).","journal-title":"Vaccine"},{"key":"BFnrmicro1703_CR12","doi-asserted-by":"publisher","first-page":"6353","DOI":"10.4049\/jimmunol.177.9.6353","volume":"177","author":"J Dietrich","year":"2006","unstructured":"Dietrich, J. et al. Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior Bacillus Calmette\u2013Guerin immunity. J. Immunol. 177, 6353\u20136360 (2006).","journal-title":"J. Immunol."},{"key":"BFnrmicro1703_CR13","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/S1473-3099(04)01206-X","volume":"4","author":"M Pai","year":"2004","unstructured":"Pai, M., Riley, L. W. & Colford, J. M. Jr. Interferon-\u03b3 assays in the immunodiagnosis of tuberculosis: a systematic review. Lancet Infect. Dis. 4, 761\u2013776 (2004).","journal-title":"Lancet Infect. Dis."},{"key":"BFnrmicro1703_CR14","doi-asserted-by":"publisher","first-page":"6332","DOI":"10.4049\/jimmunol.174.10.6332","volume":"174","author":"J Dietrich","year":"2005","unstructured":"Dietrich, J. et al. Exchanging ESAT6 with TB10.4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy. J. Immunol. 174, 6332\u20136339 (2005).","journal-title":"J. Immunol."},{"key":"BFnrmicro1703_CR15","doi-asserted-by":"publisher","first-page":"7618","DOI":"10.4049\/jimmunol.172.12.7618","volume":"172","author":"YA Skeiky","year":"2004","unstructured":"Skeiky, Y. A. et al. Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein. J. Immunol. 172, 7618\u20137628 (2004).","journal-title":"J. Immunol."},{"key":"BFnrmicro1703_CR16","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.1038\/nm1128","volume":"10","author":"H McShane","year":"2004","unstructured":"McShane, H. et al. Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans. Nature Med. 10, 1240\u20131244 (2004).","journal-title":"Nature Med."},{"key":"BFnrmicro1703_CR17","unstructured":"BIO Ventures for Global Health. Tuberculosis vaccines: The case for investment [online] (2006)."}],"container-title":["Nature Reviews Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/nrmicro1703.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/nrmicro1703","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/nrmicro1703","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/www.nature.com\/articles\/nrmicro1703.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T12:09:23Z","timestamp":1744286963000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nrmicro1703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["BFnrmicro1703"],"URL":"https:\/\/doi.org\/10.1038\/nrmicro1703","relation":{},"ISSN":["1740-1526","1740-1534"],"issn-type":[{"value":"1740-1526","type":"print"},{"value":"1740-1534","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}