{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T16:32:18Z","timestamp":1757781138713},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Rev Nephrol"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1038\/nrneph.2009.171","type":"journal-article","created":{"date-parts":[[2009,11,25]],"date-time":"2009-11-25T14:29:30Z","timestamp":1259159370000},"page":"672-673","source":"Crossref","is-referenced-by-count":8,"title":["Can ghrelin improve appetite in uremic wasting?"],"prefix":"10.1038","volume":"5","author":[{"given":"Juan Jes\u00fas","family":"Carrero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Stenvinkel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BFnrneph2009171_CR1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1053\/j.jrn.2008.10.004","volume":"19","author":"JJ Carrero","year":"2009","unstructured":"Carrero, J. J. Identification of patients with eating disorders: clinical and biochemical signs of appetite loss in dialysis patients. J. Ren. Nutr. 19, 10\u201315 (2009).","journal-title":"J. Ren. Nutr."},{"key":"BFnrneph2009171_CR2","doi-asserted-by":"publisher","first-page":"2111","DOI":"10.1681\/ASN.2005010039","volume":"16","author":"K Wynne","year":"2005","unstructured":"Wynne, K.  et al. Subcutaneous ghrelin enhances acute food intake in malnourished patients who receive maintenance peritoneal dialysis: a randomized placebo-controlled trial. J. Am. Soc. Nephrol. 16, 2111\u20132118 (2005).","journal-title":"J. Am. Soc. Nephrol."},{"key":"BFnrneph2009171_CR3","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1038\/ki.2009.114","volume":"76","author":"DR Ashby","year":"2009","unstructured":"Ashby, D. R.  et al. Sustained appetite improvement in malnourished dialysis patients by daily ghrelin treatment. Kidney Int. 76, 199\u2013206 (2009).","journal-title":"Kidney Int."},{"key":"BFnrneph2009171_CR4","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1136\/gut.2004.038737","volume":"54","author":"A Asakawa","year":"2005","unstructured":"Asakawa, A.  et al. Stomach regulates energy balance via acylated ghrelin and desacyl ghrelin. Gut 54, 18\u201324 (2005).","journal-title":"Gut"},{"key":"BFnrneph2009171_CR5","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1093\/ndt\/gfg559","volume":"19","author":"E Rodriguez Ayala","year":"2004","unstructured":"Rodriguez Ayala, E.  et al. Associations between plasma ghrelin levels and body composition in end-stage renal disease: a longitudinal study. Nephrol. Dial. Transpl. 19, 421\u2013426 (2004).","journal-title":"Nephrol. Dial. Transpl."},{"key":"BFnrneph2009171_CR6","doi-asserted-by":"crossref","unstructured":"Ashitani, J.-I., Matsumoto, N. & Nakazato, M. Ghrelin and its therapeutic potential for cachectic patients. Peptides doi: 10.1016\/j.peptides.2009.07.002","DOI":"10.1016\/j.peptides.2009.07.002"},{"key":"BFnrneph2009171_CR7","doi-asserted-by":"publisher","first-page":"2748","DOI":"10.1097\/01.ASN.0000032420.12455.74","volume":"13","author":"A Yoshimoto","year":"2002","unstructured":"Yoshimoto, A.  et al. Plasma ghrelin and desacyl ghrelin concentrations in renal failure. J. Am. Soc. Nephrol. 13, 2748\u20132752 (2002).","journal-title":"J. Am. Soc. Nephrol."},{"key":"BFnrneph2009171_CR8","doi-asserted-by":"publisher","first-page":"3674","DOI":"10.1161\/01.CIR.0000149746.62908.BB","volume":"110","author":"N Nagaya","year":"2004","unstructured":"Nagaya, N.  et al. Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation 110, 3674\u20133679 (2004).","journal-title":"Circulation"},{"key":"BFnrneph2009171_CR9","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1210\/en.2007-1046","volume":"149","author":"MD DeBoer","year":"2008","unstructured":"DeBoer, M. D.  et al. Ghrelin treatment of chronic kidney disease: Improvements in lean body mass and cytokine profile. Endocrinology 149, 827\u2013835 (2008).","journal-title":"Endocrinology"},{"key":"BFnrneph2009171_CR10","doi-asserted-by":"publisher","first-page":"5667","DOI":"10.1074\/jbc.M103898200","volume":"277","author":"M Murata","year":"2002","unstructured":"Murata, M.  et al. Ghrelin modulates the downstream molecules of insulin signaling in hepatoma cells. J. Biol. Chem. 277, 5667\u20135674 (2002).","journal-title":"J. Biol. Chem."},{"key":"BFnrneph2009171_CR11","doi-asserted-by":"publisher","first-page":"3205","DOI":"10.2337\/db08-0025","volume":"57","author":"ET Vestergaard","year":"2008","unstructured":"Vestergaard, E. T.  et al. Ghrelin infusion in humans induces acute insulin resistance and lipolysis independent of growth hormone signaling. Diabetes 57, 3205\u20133210 (2008).","journal-title":"Diabetes"},{"key":"BFnrneph2009171_CR12","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.clnu.2007.06.013","volume":"27","author":"R Barazzoni","year":"2008","unstructured":"Barazzoni, R.  et al. Higher total ghrelin levels are associated with higher insulin-mediated glucose disposal in non-diabetic maintenance hemodialysis patients. Clin. Nutr. 27, 142\u2013149 (2008).","journal-title":"Clin. Nutr."},{"key":"BFnrneph2009171_CR13","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.1172\/JCI25811","volume":"116","author":"C Theander-Carrillo","year":"2006","unstructured":"Theander-Carrillo, C.  et al. Ghrelin action in the brain controls adipocyte metabolism. J. Clin. Invest. 116, 1983\u20131993 (2006).","journal-title":"J. Clin. Invest."}],"container-title":["Nature Reviews Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nrneph.2009.171.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrneph.2009.171","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrneph.2009.171.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T04:31:40Z","timestamp":1684470700000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nrneph.2009.171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["BFnrneph2009171"],"URL":"https:\/\/doi.org\/10.1038\/nrneph.2009.171","relation":{},"ISSN":["1759-5061","1759-507X"],"issn-type":[{"value":"1759-5061","type":"print"},{"value":"1759-507X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}