{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T07:16:13Z","timestamp":1792826173488,"version":"4.5.0"},"reference-count":167,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T00:00:00Z","timestamp":1412640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Rev Neurol"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1038\/nrneurol.2014.178","type":"journal-article","created":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T10:15:47Z","timestamp":1412676947000},"page":"620-633","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":312,"title":["Brain connectivity in neurodegenerative diseases\u2014from phenotype to proteinopathy"],"prefix":"10.1038","volume":"10","author":[{"given":"Michela","family":"Pievani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Filippini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martijn P.","family":"van den Heuvel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano F.","family":"Cappa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni B.","family":"Frisoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,10,7]]},"reference":[{"key":"BFnrneurol2014178_CR1","doi-asserted-by":"publisher","first-page":"1991","DOI":"10.1126\/science.1067122","volume":"296","author":"JP Taylor","year":"2002","unstructured":"Taylor, J. P., Hardy, J. & Fischbeck, K. H. Toxic proteins in neurodegenerative disease. Science 296, 1991\u20131995 (2002).","journal-title":"Science"},{"key":"BFnrneurol2014178_CR2","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/S1474-4422(13)70044-9","volume":"12","author":"VL Villemagne","year":"2013","unstructured":"Villemagne, V. L. et al. Amyloid \u03b2 deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study. Lancet Neurol. 12, 357\u2013367 (2013).","journal-title":"Lancet Neurol."},{"key":"BFnrneurol2014178_CR3","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1038\/nrneurol.2009.215","volume":"6","author":"GB Frisoni","year":"2010","unstructured":"Frisoni, G. B., Fox, N. C., Jack, C. R. Jr, Scheltens, P. & Thompson, P. M. The clinical use of structural MRI in Alzheimer disease. Nat. Rev. Neurol. 6, 67\u201377 (2010).","journal-title":"Nat. Rev. Neurol."},{"key":"BFnrneurol2014178_CR4","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1038\/nrneurol.2012.7","volume":"8","author":"JL Whitwell","year":"2012","unstructured":"Whitwell, J. L. & Josephs, K. A. Neuroimaging in frontotemporal lobar degeneration\u2014predicting molecular pathology. Nat. Rev. Neurol. 8, 131\u2013142 (2012).","journal-title":"Nat. Rev. Neurol."},{"key":"BFnrneurol2014178_CR5","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.neuron.2009.03.024","volume":"62","author":"WW Seeley","year":"2009","unstructured":"Seeley, W. W., Crawford, R. K., Zhou, J., Miller, B. L. & Greicius, M. D. Neurodegenerative diseases target large-scale human brain networks. Neuron 62, 42\u201352 (2009).","journal-title":"Neuron"},{"key":"BFnrneurol2014178_CR6","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1016\/j.neuron.2011.12.040","volume":"73","author":"A Raj","year":"2012","unstructured":"Raj, A., Kuceyeski, A. & Weiner, M. A network diffusion model of disease progression in dementia. Neuron 73, 1204\u20131215 (2012).","journal-title":"Neuron"},{"key":"BFnrneurol2014178_CR7","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1038\/jcbfm.1987.118","volume":"7","author":"JR Moeller","year":"1987","unstructured":"Moeller, J. R., Strother, S. C., Sidtism, J. J. & Rottenberg, D. A. Scaled subprofile model: a statistical approach to the analysis of functional patterns in positron emission tomographic data. J. Cereb. Blood Flow Metab. 7, 649\u2013658 (1987).","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"BFnrneurol2014178_CR8","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/0020-7101(90)90039-W","volume":"26","author":"B Horwitz","year":"1990","unstructured":"Horwitz, B. Simulating functional interactions in the brain: a model for examining correlations between regonal cerebral metabolic rates. Int. J. Biomed. Comput. 26, 149\u2013170 (1990).","journal-title":"Int. J. Biomed. Comput."},{"key":"BFnrneurol2014178_CR9","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1002\/hbm.460020107","volume":"2","author":"KJ Friston","year":"1994","unstructured":"Friston, K. J. Functional and effective connectivity in neuroimaging: a synthesis. Hum. Brain Mapp. 2, 56\u201378 (1994).","journal-title":"Hum. Brain Mapp."},{"key":"BFnrneurol2014178_CR10","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1002\/mrm.1910340409","volume":"34","author":"B Biswal","year":"1995","unstructured":"Biswal, B., Yetkin, F. Z., Haughton, V. M. & Hyde, J. S. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn. Reson. Med. 34, 537\u2013541 (1995).","journal-title":"Magn. Reson. Med."},{"key":"BFnrneurol2014178_CR11","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.biopsych.2006.09.020","volume":"62","author":"MD Greicius","year":"2007","unstructured":"Greicius, M. D. et al. Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus. Biol. Psychiatry 62, 429\u2013437 (2007).","journal-title":"Biol. Psychiatry"},{"key":"BFnrneurol2014178_CR12","doi-asserted-by":"publisher","first-page":"4637","DOI":"10.1073\/pnas.0308627101","volume":"101","author":"MD Greicius","year":"2004","unstructured":"Greicius, M. D., Srivastava, G., Reiss, A. L. & Menon, V. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc. Natl Acad. Sci. USA 101, 4637\u20134642 (2004).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR13","doi-asserted-by":"publisher","first-page":"18760","DOI":"10.1073\/pnas.0708803104","volume":"104","author":"C Sorg","year":"2007","unstructured":"Sorg, C. et al. Selective changes of resting-state networks in individuals at risk for Alzheimer's disease. Proc. Natl Acad. Sci. USA 104, 18760\u201318765 (2007).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR14","doi-asserted-by":"publisher","first-page":"13848","DOI":"10.1073\/pnas.0601417103","volume":"103","author":"JS Damoiseaux","year":"2006","unstructured":"Damoiseaux, J. S. et al. Consistent resting-state networks across healthy subjects. Proc. Natl Acad. Sci. USA. 103, 13848\u201313853 (2006).","journal-title":"Proc. Natl Acad. Sci. USA."},{"key":"BFnrneurol2014178_CR15","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.brainres.2008.08.028","volume":"1239","author":"S Chen","year":"2008","unstructured":"Chen, S. et al. Group independent component analysis reveals consistent resting-state networks across multiple sessions. Brain Res. 1239, 141\u2013151 (2008).","journal-title":"Brain Res."},{"key":"BFnrneurol2014178_CR16","doi-asserted-by":"publisher","first-page":"2487","DOI":"10.1097\/00001756-200212200-00022","volume":"13","author":"RI Goldman","year":"2002","unstructured":"Goldman, R. I., Stern, J. M., Engel, J. Jr & Cohen, M. S. Simultaneous EEG and fMRI of the alpha rhythm. Neuroreport 13, 2487\u20132492 (2002).","journal-title":"Neuroreport"},{"key":"BFnrneurol2014178_CR17","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1073\/pnas.98.2.676","volume":"98","author":"ME Raichle","year":"2001","unstructured":"Raichle, M. E. et al. A default mode of brain function. Proc. Natl Acad. Sci. USA 98, 676\u2013682 (2001).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR18","doi-asserted-by":"publisher","first-page":"4734","DOI":"10.1073\/pnas.0911855107","volume":"107","author":"BB Biswal","year":"2010","unstructured":"Biswal, B. B. et al. Toward discovery science of human brain function. Proc. Natl Acad. Sci. USA 107, 4734\u20134739 (2010).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR19","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1038\/jcbfm.2008.25","volume":"28","author":"M Fukunaga","year":"2008","unstructured":"Fukunaga, M. et al. Metabolic origin of BOLD signal fluctuations in the absence of stimuli. J. Cereb. Blood Flow Metab. 28, 1377\u20131387 (2008).","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"BFnrneurol2014178_CR20","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1038\/nature05758","volume":"447","author":"JL Vincent","year":"2007","unstructured":"Vincent, J. L. et al. Intrinsic functional architecture in the anaesthetized monkey brain. Nature 447, 83\u201386 (2007).","journal-title":"Nature"},{"key":"BFnrneurol2014178_CR21","doi-asserted-by":"publisher","first-page":"3979","DOI":"10.1073\/pnas.1200506109","volume":"109","author":"H Lu","year":"2012","unstructured":"Lu, H. et al. Rat brains also have a default mode network. Proc. Natl Acad. Sci. USA 109, 3979\u20133984 (2012).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR22","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1093\/brain\/awt162","volume":"137","author":"R Leech","year":"2014","unstructured":"Leech, R. & Sharp, D. J. The role of the posterior cingulate cortex in cognition and disease. Brain 137, 12\u201332 (2014).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR23","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1523\/JNEUROSCI.4227-13.2014","volume":"34","author":"AV Utevsky","year":"2014","unstructured":"Utevsky, A. V., Smith, D. V. & Huettel, S. A. Precuneus is a functional core of the default-mode network. J. Neurosci. 34, 932\u2013940 (2014).","journal-title":"J. Neurosci."},{"key":"BFnrneurol2014178_CR24","doi-asserted-by":"publisher","first-page":"2349","DOI":"10.1523\/JNEUROSCI.5587-06.2007","volume":"27","author":"WW Seeley","year":"2007","unstructured":"Seeley, W. W. et al. Dissociable intrinsic connectivity networks for salience processing and executive control. J. Neurosci. 27, 2349\u20132356 (2007).","journal-title":"J. Neurosci."},{"key":"BFnrneurol2014178_CR25","doi-asserted-by":"publisher","first-page":"13040","DOI":"10.1073\/pnas.0905267106","volume":"106","author":"SM Smith","year":"2009","unstructured":"Smith, S. M. et al. Correspondence of the brain's functional architecture during activation and rest. Proc. Natl Acad. Sci. USA 106, 13040\u201313045 (2009).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR26","doi-asserted-by":"publisher","first-page":"1740","DOI":"10.1152\/jn.90463.2008","volume":"100","author":"D Zhang","year":"2008","unstructured":"Zhang, D. et al. Intrinsic functional relations between human cerebral cortex and thalamus. J. Neurophysiol. 100, 1740\u20131748 (2008).","journal-title":"J. Neurophysiol."},{"key":"BFnrneurol2014178_CR27","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/j.nurt.2007.05.011","volume":"4","author":"AL Alexander","year":"2007","unstructured":"Alexander, A. L., Lee, J. E., Lazar, M. & Field, A. S. Diffusion tensor imaging of the brain. Neurotherapeutics 4, 316\u2013329 (2007).","journal-title":"Neurotherapeutics"},{"key":"BFnrneurol2014178_CR28","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1016\/j.cortex.2008.05.004","volume":"44","author":"M Catani","year":"2008","unstructured":"Catani, M. & Thiebaut de Schotten, M. A diffusion tensor imaging tractography atlas for virtual in vivo dissections. Cortex 44, 1105\u20131132 (2008).","journal-title":"Cortex"},{"key":"BFnrneurol2014178_CR29","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1212\/WNL.0b013e31820af94e","volume":"76","author":"JR Petrella","year":"2011","unstructured":"Petrella, J. R., Sheldon, F. C., Prince, S. E., Calhoun, V. D. & Doraiswamy, P. M. Default mode network connectivity in stable vs progressive mild cognitive impairment. Neurology 76, 511\u2013517 (2011).","journal-title":"Neurology"},{"key":"BFnrneurol2014178_CR30","doi-asserted-by":"publisher","first-page":"1564","DOI":"10.1016\/j.neurobiolaging.2011.06.007","volume":"33","author":"F Agosta","year":"2012","unstructured":"Agosta, F. et al. Resting state fMRI in Alzheimer's disease: beyond the default mode network. Neurobiol. Aging 33, 1564\u20131578 (2012).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR31","doi-asserted-by":"publisher","first-page":"2018","DOI":"10.1016\/j.neurobiolaging.2011.07.003","volume":"33","author":"MA Binnewijzend","year":"2012","unstructured":"Binnewijzend, M. A. et al. Resting-state fMRI changes in Alzheimer's disease and mild cognitive impairment. Neurobiol. Aging 33, 2018\u20132028 (2012).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR32","doi-asserted-by":"publisher","first-page":"8890","DOI":"10.1523\/JNEUROSCI.5698-11.2012","volume":"32","author":"MR Brier","year":"2012","unstructured":"Brier, M. R. et al. Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression. J. Neurosci. 32, 8890\u20138899 (2012).","journal-title":"J. Neurosci."},{"key":"BFnrneurol2014178_CR33","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1148\/radiol.10091701","volume":"256","author":"HY Zhang","year":"2010","unstructured":"Zhang, H. Y. et al. Resting brain connectivity: changes during the progress of Alzheimer disease. Radiology 256, 598\u2013606 (2010).","journal-title":"Radiology"},{"key":"BFnrneurol2014178_CR34","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.biopsych.2013.04.015","volume":"74","author":"G Zamboni","year":"2013","unstructured":"Zamboni, G. et al. Resting functional connectivity reveals residual functional activity in Alzheimer's disease. Biol. Psychiatry 74, 375\u2013383 (2013).","journal-title":"Biol. Psychiatry"},{"key":"BFnrneurol2014178_CR35","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.1093\/brain\/awq075","volume":"133","author":"J Zhou","year":"2010","unstructured":"Zhou, J. et al. Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease. Brain 133, 1352\u20131367 (2010).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR36","doi-asserted-by":"publisher","first-page":"828.e19","DOI":"10.1016\/j.neurobiolaging.2011.06.024","volume":"33","author":"JS Damoiseaux","year":"2012","unstructured":"Damoiseaux, J. S., Prater, K. E., Miller, B. L. & Greicius, M. D. Functional connectivity tracks clinical deterioration in Alzheimer's disease. Neurobiol. Aging 33, 828.e19\u2013828.e30 (2012).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR37","doi-asserted-by":"publisher","first-page":"1862","DOI":"10.1002\/hbm.20978","volume":"31","author":"M Pievani","year":"2010","unstructured":"Pievani, M. et al. Assessment of white matter tract damage in mild cognitive impairment and Alzheimer's disease. Hum. Brain Mapp. 31, 1862\u20131875 (2010).","journal-title":"Hum. Brain Mapp."},{"key":"BFnrneurol2014178_CR38","doi-asserted-by":"publisher","first-page":"2029","DOI":"10.1016\/j.neurobiolaging.2011.06.027","volume":"33","author":"H Huang","year":"2012","unstructured":"Huang, H. et al. Distinctive disruption patterns of white matter tracts in Alzheimer's disease with full diffusion tensor characterization. Neurobiol. Aging 33, 2029\u20132045 (2012).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR39","doi-asserted-by":"publisher","first-page":"e49072","DOI":"10.1371\/journal.pone.0049072","volume":"7","author":"J Acosta-Cabronero","year":"2012","unstructured":"Acosta-Cabronero, J., Alley, S., Williams, G. B., Pengas, G. & Nestor, P. J. Diffusion tensor metrics as biomarkers in Alzheimer's disease. PLoS ONE 7, e49072 (2012).","journal-title":"PLoS ONE"},{"key":"BFnrneurol2014178_CR40","doi-asserted-by":"publisher","first-page":"2147","DOI":"10.1523\/JNEUROSCI.4437-12.2013","volume":"33","author":"G Douaud","year":"2013","unstructured":"Douaud, G. et al. Brain microstructure reveals early abnormalities more than two years prior to clinical progression from mild cognitive impairment to Alzheimer's disease. J. Neurosci. 33, 2147\u20132155 (2013).","journal-title":"J. Neurosci."},{"key":"BFnrneurol2014178_CR41","doi-asserted-by":"publisher","first-page":"2579","DOI":"10.1093\/brain\/awp071","volume":"132","author":"Y Zhang","year":"2009","unstructured":"Zhang, Y. et al. White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI. Brain 132, 2579\u20132592 (2009).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR42","doi-asserted-by":"publisher","first-page":"2389","DOI":"10.1016\/j.cortex.2012.09.017","volume":"49","author":"M Filippi","year":"2013","unstructured":"Filippi, M. et al. Functional network connectivity in the behavioral variant of frontotemporal dementia. Cortex 49, 2389\u20132401 (2013).","journal-title":"Cortex"},{"key":"BFnrneurol2014178_CR43","doi-asserted-by":"publisher","first-page":"e63727","DOI":"10.1371\/journal.pone.0063727","volume":"8","author":"J Song","year":"2013","unstructured":"Song, J. et al. Aberrant functional organization within and between resting-state networks in AD. PLoS ONE 8, e63727 (2013).","journal-title":"PLoS ONE"},{"key":"BFnrneurol2014178_CR44","doi-asserted-by":"publisher","first-page":"1856","DOI":"10.1016\/j.cortex.2012.09.008","volume":"49","author":"NA Farb","year":"2013","unstructured":"Farb, N. A. et al. Abnormal network connectivity in frontotemporal dementia: evidence for prefrontal isolation. Cortex 49, 1856\u20131873 (2013).","journal-title":"Cortex"},{"key":"BFnrneurol2014178_CR45","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1001\/archneur.64.2.246","volume":"64","author":"B Borroni","year":"2007","unstructured":"Borroni, B. et al. Evidence of white matter changes on diffusion tensor imaging in frontotemporal dementia. Arch. Neurol. 64, 246\u2013251 (2007).","journal-title":"Arch. Neurol."},{"key":"BFnrneurol2014178_CR46","doi-asserted-by":"publisher","first-page":"2502","DOI":"10.1093\/brain\/awr173","volume":"134","author":"M Hornberger","year":"2011","unstructured":"Hornberger, M., Geng, J. & Hodges, J. R. Convergent grey and white matter evidence of orbitofrontal cortex changes related to disinhibition in behavioural variant frontotemporal dementia. Brain 134, 2502\u20132512 (2011).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR47","doi-asserted-by":"publisher","first-page":"4163","DOI":"10.1002\/hbm.22468","volume":"35","author":"CJ Mahoney","year":"2014","unstructured":"Mahoney, C. J. et al. Profiles of white matter tract pathology in frontotemporal dementia. Hum. Brain Mapp. 35, 4163\u20134179 (2014).","journal-title":"Hum. Brain Mapp."},{"key":"BFnrneurol2014178_CR48","doi-asserted-by":"publisher","first-page":"e102656","DOI":"10.1371\/journal.pone.0102656","volume":"9","author":"F Tovar-Moll","year":"2014","unstructured":"Tovar-Moll, F. et al. White matter tract damage in the behavioral variant of frontotemporal and corticobasal dementia syndromes. PLoS ONE 9, e102656 (2014).","journal-title":"PLoS ONE"},{"key":"BFnrneurol2014178_CR49","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1212\/WNL.0b013e31822c61f2","volume":"77","author":"JL Whitwell","year":"2011","unstructured":"Whitwell, J. L. et al. Altered functional connectivity in asymptomatic MAPT subjects: a comparison to bvFTD. Neurology 77, 866\u2013874 (2011).","journal-title":"Neurology"},{"key":"BFnrneurol2014178_CR50","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1002\/ana.23844","volume":"73","author":"RC Gardner","year":"2013","unstructured":"Gardner, R. C. et al. Intrinsic connectivity network disruption in progressive supranuclear palsy. Ann. Neurol. 73, 603\u2013616 (2013).","journal-title":"Ann. Neurol."},{"key":"BFnrneurol2014178_CR51","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1016\/j.parkreldis.2011.05.013","volume":"17","author":"JL Whitwell","year":"2011","unstructured":"Whitwell, J. L. et al. Disrupted thalamocortical connectivity in PSP: a resting-state fMRI, DTI, and VBM study. Parkinsonism Relat. Disord. 17, 599\u2013605 (2011).","journal-title":"Parkinsonism Relat. Disord."},{"key":"BFnrneurol2014178_CR52","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1001\/archneur.63.1.81","volume":"63","author":"AL Boxer","year":"2006","unstructured":"Boxer, A. L. et al. Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy. Arch. Neurol. 63, 81\u201386 (2006).","journal-title":"Arch. Neurol."},{"key":"BFnrneurol2014178_CR53","doi-asserted-by":"publisher","first-page":"1752","DOI":"10.1002\/mds.23739","volume":"26","author":"E Canu","year":"2011","unstructured":"Canu, E. et al. Diffusion tensor magnetic resonance imaging tractography in progressive supranuclear palsy. Mov. Disord. 26, 1752\u20131755 (2011).","journal-title":"Mov. Disord."},{"key":"BFnrneurol2014178_CR54","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1001\/archneurol.2011.107","volume":"68","author":"JL Whitwell","year":"2011","unstructured":"Whitwell, J. L. et al. Clinical correlates of white matter tract degeneration in progressive supranuclear palsy. Arch. Neurol. 68, 753\u2013760 (2011).","journal-title":"Arch. Neurol."},{"key":"BFnrneurol2014178_CR55","doi-asserted-by":"publisher","first-page":"2253","DOI":"10.1093\/brain\/awt118","volume":"136","author":"SA Sajjadi","year":"2013","unstructured":"Sajjadi, S. A. et al. Diffusion tensor magnetic resonance imaging for single subject diagnosis in neurodegenerative diseases. Brain 136, 2253\u20132261 (2013).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR56","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.expneurol.2009.01.025","volume":"217","author":"B Mohammadi","year":"2009","unstructured":"Mohammadi, B. et al. Changes of resting state brain networks in amyotrophic lateral sclerosis. Exp. Neurol. 217, 147\u2013153 (2009).","journal-title":"Exp. Neurol."},{"key":"BFnrneurol2014178_CR57","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1016\/j.neurobiolaging.2010.07.011","volume":"33","author":"G Tedeschi","year":"2012","unstructured":"Tedeschi, G. et al. Interaction between aging and neurodegeneration in amyotrophic lateral sclerosis. Neurobiol. Aging 33, 886\u2013898 (2012).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR58","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1097\/WNR.0b013e328363148c","volume":"24","author":"F Zhou","year":"2013","unstructured":"Zhou, F. et al. Altered motor network functional connectivity in amyotrophic lateral sclerosis: a resting-state functional magnetic resonance imaging study. Neuroreport 24, 657\u2013662 (2013).","journal-title":"Neuroreport"},{"key":"BFnrneurol2014178_CR59","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.neulet.2013.11.022","volume":"558","author":"F Zhou","year":"2014","unstructured":"Zhou, F. et al. Alterations in regional functional coherence within the sensory-motor network in amyotrophic lateral sclerosis. Neurosci. Lett. 558, 192\u2013196 (2014).","journal-title":"Neurosci. Lett."},{"key":"BFnrneurol2014178_CR60","doi-asserted-by":"publisher","first-page":"e13664","DOI":"10.1371\/journal.pone.0013664","volume":"5","author":"E Verstraete","year":"2010","unstructured":"Verstraete, E. et al. Motor network degeneration in amyotrophic lateral sclerosis: a structural and functional connectivity study. PLoS ONE 5, e13664 (2010).","journal-title":"PLoS ONE"},{"key":"BFnrneurol2014178_CR61","doi-asserted-by":"publisher","first-page":"3470","DOI":"10.1093\/brain\/awr279","volume":"134","author":"G Douaud","year":"2011","unstructured":"Douaud, G., Filippini, N., Knight, S., Talbot, K. & Turner, M. R. Integration of structural and functional magnetic resonance imaging in amyotrophic lateral sclerosis. Brain 134, 3470\u20133479 (2011).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR62","doi-asserted-by":"publisher","first-page":"e24239","DOI":"10.1371\/journal.pone.0024239","volume":"6","author":"E Verstraete","year":"2011","unstructured":"Verstraete, E., Veldink, J. H., Mandl, R. C., van den Berg, L. H. & van den Heuvel, M. P. Impaired structural motor connectome in amyotrophic lateral sclerosis. PLoS ONE 6, e24239 (2011).","journal-title":"PLoS ONE"},{"key":"BFnrneurol2014178_CR63","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.3174\/ajnr.A2105","volume":"31","author":"F Agosta","year":"2010","unstructured":"Agosta, F. et al. Assessment of white matter tract damage in patients with amyotrophic lateral sclerosis: a diffusion tensor MR imaging tractography study. AJNR Am. J. Neuroradiol. 31, 1457\u20131461 (2010).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"BFnrneurol2014178_CR64","doi-asserted-by":"publisher","first-page":"2661","DOI":"10.1016\/j.neuroimage.2011.08.054","volume":"59","author":"S Rose","year":"2012","unstructured":"Rose, S. et al. Direct evidence of intra- and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: an automated MRI structural connectivity study. Neuroimage 59, 2661\u20132669 (2012).","journal-title":"Neuroimage"},{"key":"BFnrneurol2014178_CR65","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1212\/WNL.0b013e31829c5eee","volume":"81","author":"P Bede","year":"2013","unstructured":"Bede, P. et al. Multiparametric MRI study of ALS stratified for the C9orf72 genotype. Neurology 81, 361\u2013369 (2013).","journal-title":"Neurology"},{"key":"BFnrneurol2014178_CR66","doi-asserted-by":"publisher","first-page":"553","DOI":"10.3109\/21678421.2013.785569","volume":"14","author":"F Trojsi","year":"2013","unstructured":"Trojsi, F. et al. Motor and extramotor neurodegeneration in amyotrophic lateral sclerosis: a 3 T high angular resolution diffusion imaging (HARDI) study. Amyotroph. Lateral Scler. Frontotemporal Degener. 14, 553\u2013561 (2013).","journal-title":"Amyotroph. Lateral Scler. Frontotemporal Degener."},{"key":"BFnrneurol2014178_CR67","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1136\/jnnp.2006.101758","volume":"78","author":"L Thivard","year":"2007","unstructured":"Thivard, L. et al. Diffusion tensor imaging and voxel based morphometry study in amyotrophic lateral sclerosis: relationships with motor disability. J. Neurol. Neurosurg. Psychiatry 78, 889\u2013892 (2007).","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"BFnrneurol2014178_CR68","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1007\/s00415-013-7215-5","volume":"261","author":"J Zhang","year":"2014","unstructured":"Zhang, J. et al. Regional alterations in cortical thickness and white matter integrity in amyotrophic lateral sclerosis. J. Neurol. 261, 412\u2013421 (2014).","journal-title":"J. Neurol."},{"key":"BFnrneurol2014178_CR69","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1001\/archneurol.2008.527","volume":"66","author":"BR Stanton","year":"2009","unstructured":"Stanton, B. R. et al. Diffusion tensor imaging in sporadic and familial (D90A SOD1) forms of amyotrophic lateral sclerosis. Arch. Neurol. 66, 109\u2013115 (2009).","journal-title":"Arch. Neurol."},{"key":"BFnrneurol2014178_CR70","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1136\/jnnp.2010.236018","volume":"82","author":"CR Blain","year":"2011","unstructured":"Blain, C. R. et al. Differential corticospinal tract degeneration in homozygous 'D90A' SOD-1 ALS and sporadic ALS. J. Neurol. Neurosurg. Psychiatry 82, 843\u2013849 (2011).","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"BFnrneurol2014178_CR71","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cortex.2014.01.002","volume":"53","author":"C Crespi","year":"2014","unstructured":"Crespi, C. et al. Microstructural white matter correlates of emotion recognition impairment in amyotrophic lateral sclerosis. Cortex 53, 1\u20138 (2014).","journal-title":"Cortex"},{"key":"BFnrneurol2014178_CR72","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/j.neuroimage.2006.09.025","volume":"34","author":"CA Sage","year":"2007","unstructured":"Sage, C. A., Peeters, R. R., G\u00f6rner, A., Robberecht, W. & Sunaert, S. Quantitative diffusion tensor imaging in amyotrophic lateral sclerosis. Neuroimage 34, 486\u2013499 (2007).","journal-title":"Neuroimage"},{"key":"BFnrneurol2014178_CR73","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/1471-2202-13-141","volume":"13","author":"C Keil","year":"2012","unstructured":"Keil, C. et al. Longitudinal diffusion tensor imaging in amyotrophic lateral sclerosis. BMC Neurosci. 13, 141 (2012).","journal-title":"BMC Neurosci."},{"key":"BFnrneurol2014178_CR74","doi-asserted-by":"publisher","first-page":"59","DOI":"10.3109\/17482968.2010.517850","volume":"12","author":"J Senda","year":"2011","unstructured":"Senda, J. et al. Progressive and widespread brain damage in ALS: MRI voxel-based morphometry and diffusion tensor imaging study. Amyotroph. Lateral Scler. 12, 59\u201369 (2011).","journal-title":"Amyotroph. Lateral Scler."},{"key":"BFnrneurol2014178_CR75","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1002\/hbm.22258","volume":"35","author":"E Verstraete","year":"2014","unstructured":"Verstraete, E., Veldink, J. H., van den Berg, L. H. & van den Heuvel, M. P. Structural brain network imaging shows expanding disconnection of the motor system in amyotrophic lateral sclerosis. Hum. Brain Mapp. 35, 1351\u20131361 (2014).","journal-title":"Hum. Brain Mapp."},{"key":"BFnrneurol2014178_CR76","doi-asserted-by":"publisher","first-page":"2291","DOI":"10.1093\/cercor\/bhr002","volume":"21","author":"F Agosta","year":"2011","unstructured":"Agosta, F. et al. Sensorimotor functional connectivity changes in amyotrophic lateral sclerosis. Cereb. Cortex 21, 2291\u20132298 (2011).","journal-title":"Cereb. Cortex"},{"key":"BFnrneurol2014178_CR77","doi-asserted-by":"publisher","first-page":"4386","DOI":"10.1002\/hbm.22481","volume":"35","author":"R Schmidt","year":"2014","unstructured":"Schmidt, R. et al. Correlation between structural and functional connectivity impairment in amyotrophic lateral sclerosis. Hum. Brain Mapp. 35, 4386\u20134395 (2014).","journal-title":"Hum. Brain Mapp."},{"key":"BFnrneurol2014178_CR78","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.neurobiolaging.2012.04.015","volume":"34","author":"F Agosta","year":"2013","unstructured":"Agosta, F. et al. Divergent brain network connectivity in amyotrophic lateral sclerosis. Neurobiol. Aging 34, 419\u2013427 (2013).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR79","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1093\/brain\/awt007","volume":"136","author":"F Esposito","year":"2013","unstructured":"Esposito, F. et al. Rhythm-specific modulation of the sensorimotor network in drug-naive patients with Parkinson's disease by levodopa. Brain 136, 710\u2013725 (2013).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR80","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1016\/j.neurobiolaging.2013.08.018","volume":"35","author":"C Luo","year":"2014","unstructured":"Luo, C. et al. Reduced functional connectivity in early-stage drug-naive Parkinson's disease: a resting-state fMRI study. Neurobiol. Aging 35, 431\u2013441 (2014).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR81","doi-asserted-by":"publisher","first-page":"143","DOI":"10.3389\/fnsys.2010.00143","volume":"4","author":"Y Kwak","year":"2010","unstructured":"Kwak, Y. et al. Altered resting state cortico-striatal connectivity in mild to moderate stage Parkinson's disease. Front. Syst. Neurosci. 4, 143 (2010).","journal-title":"Front. Syst. Neurosci."},{"key":"BFnrneurol2014178_CR82","doi-asserted-by":"publisher","first-page":"e59717","DOI":"10.1371\/journal.pone.0059717","volume":"8","author":"R Yu","year":"2013","unstructured":"Yu, R., Liu, B., Wang, L., Chen, J. & Liu, X. Enhanced functional connectivity between putamen and supplementary motor area in Parkinson's disease patients. PLoS ONE 8, e59717 (2013).","journal-title":"PLoS ONE"},{"key":"BFnrneurol2014178_CR83","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.neulet.2009.05.046","volume":"460","author":"T Wu","year":"2009","unstructured":"Wu, T. et al. Changes of functional connectivity of the motor network in the resting state in Parkinson's disease. Neurosci. Lett. 460, 6\u201310 (2009).","journal-title":"Neurosci. Lett."},{"key":"BFnrneurol2014178_CR84","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1093\/cercor\/bhp178","volume":"20","author":"RC Helmich","year":"2010","unstructured":"Helmich, R. C. et al. I. Spatial remapping of cortico-striatal connectivity in Parkinson's disease. Cereb. Cortex 20, 1175\u20131186 (2010).","journal-title":"Cereb. Cortex"},{"key":"BFnrneurol2014178_CR85","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.brainres.2013.06.027","volume":"1527","author":"IH Choe","year":"2013","unstructured":"Choe, I. H., Yeo, S., Chung, K. C., Kim, S. H. & Lim, S. Decreased and increased cerebral regional homogeneity in early Parkinson's disease. Brain Res. 1527, 230\u2013237 (2013).","journal-title":"Brain Res."},{"key":"BFnrneurol2014178_CR86","doi-asserted-by":"publisher","first-page":"3699","DOI":"10.1093\/brain\/aws281","volume":"135","author":"CD Hacker","year":"2012","unstructured":"Hacker, C. D., Perlmutter, J. S., Criswell, S. R., Ances, B. M. & Snyder, A. Z. Resting state functional connectivity of the striatum in Parkinson's disease. Brain 135, 3699\u20133711 (2012).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR87","doi-asserted-by":"publisher","first-page":"e77336","DOI":"10.1371\/journal.pone.0077336","volume":"8","author":"M G\u00f6ttlich","year":"2013","unstructured":"G\u00f6ttlich, M. et al. Altered resting state brain networks in Parkinson's disease. PLoS ONE 8, e77336 (2013).","journal-title":"PLoS ONE"},{"key":"BFnrneurol2014178_CR88","doi-asserted-by":"publisher","first-page":"2798","DOI":"10.1002\/hbm.22101","volume":"34","author":"F Agosta","year":"2013","unstructured":"Agosta, F. et al. The topography of brain damage at different stages of Parkinson's disease. Hum. Brain Mapp. 34, 2798\u20132807 (2013).","journal-title":"Hum. Brain Mapp."},{"key":"BFnrneurol2014178_CR89","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1212\/WNL.0b013e3182929f62","volume":"80","author":"TR Melzer","year":"2013","unstructured":"Melzer, T. R. et al. White matter microstructure deteriorates across cognitive stages in Parkinson disease. Neurology 80, 1841\u20131849 (2013).","journal-title":"Neurology"},{"key":"BFnrneurol2014178_CR90","doi-asserted-by":"publisher","first-page":"2226","DOI":"10.1212\/WNL.0b013e31827689d6","volume":"79","author":"A Tessitore","year":"2012","unstructured":"Tessitore, A. et al. Default-mode network connectivity in cognitively unimpaired patients with Parkinson disease. Neurology 79, 2226\u20132232 (2012).","journal-title":"Neurology"},{"key":"BFnrneurol2014178_CR91","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.nicl.2013.03.001","volume":"2","author":"EM Dumas","year":"2013","unstructured":"Dumas, E. M. et al. Reduced functional brain connectivity prior to and after disease onset in Huntington's disease. Neuroimage Clin. 2, 377\u2013384 (2013).","journal-title":"Neuroimage Clin."},{"key":"BFnrneurol2014178_CR92","first-page":"87","volume":"39","author":"GR Poudel","year":"2014","unstructured":"Poudel, G. R. et al. Abnormal synchrony of resting state networks in premanifest and symptomatic Huntington disease: the IMAGE-HD study. J. Psychiatry Neurosci. 39, 87\u201396 (2014).","journal-title":"J. Psychiatry Neurosci."},{"key":"BFnrneurol2014178_CR93","doi-asserted-by":"publisher","first-page":"2582","DOI":"10.1002\/hbm.22351","volume":"35","author":"CJ Werner","year":"2014","unstructured":"Werner, C. J. et al. Altered resting-state connectivity in Huntington's disease. Hum. Brain Mapp. 35, 2582\u20132593 (2014).","journal-title":"Hum. Brain Mapp."},{"key":"BFnrneurol2014178_CR94","doi-asserted-by":"publisher","first-page":"e72159","DOI":"10.1371\/journal.pone.0072159","volume":"8","author":"M Quarantelli","year":"2013","unstructured":"Quarantelli, M. et al. Default-mode network changes in Huntington's disease: an integrated MRI study of functional connectivity and morphometry. PLoS ONE 8, e72159 (2013).","journal-title":"PLoS ONE"},{"key":"BFnrneurol2014178_CR95","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.bbr.2008.11.020","volume":"199","author":"JA Grahn","year":"2009","unstructured":"Grahn, J. A., Parkinson, J. A. & Owen, A. M. The role of the basal ganglia in learning and memory: neuropsychological studies. Behav. Brain Res. 199, 53\u201360 (2009).","journal-title":"Behav. Brain Res."},{"key":"BFnrneurol2014178_CR96","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.cortex.2013.11.009","volume":"52","author":"MJ Novak","year":"2014","unstructured":"Novak, M. J. et al. White matter integrity in premanifest and early Huntington's disease is related to caudate loss and disease progression. Cortex 52, 98\u2013112 (2014).","journal-title":"Cortex"},{"key":"BFnrneurol2014178_CR97","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.3174\/ajnr.A2128","volume":"31","author":"R Della Nave","year":"2010","unstructured":"Della Nave, R. et al. Regional distribution and clinical correlates of white matter structural damage in Huntington disease: a tract-based spatial statistics study. AJNR Am. J. Neuroradiol. 31, 1675\u20131681 (2010).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"BFnrneurol2014178_CR98","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.nbd.2011.02.010","volume":"42","author":"I Bohanna","year":"2011","unstructured":"Bohanna, I., Georgiou-Karistianis, N. & Egan, G. F. Connectivity-based segmentation of the striatum in Huntington's disease: vulnerability of motor pathways. Neurobiol. Dis. 42, 475\u2013481 (2011).","journal-title":"Neurobiol. Dis."},{"key":"BFnrneurol2014178_CR99","doi-asserted-by":"publisher","first-page":"2995","DOI":"10.1016\/j.neuroimage.2009.10.015","volume":"49","author":"HD Rosas","year":"2010","unstructured":"Rosas, H. D. et al. Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical \u201cdisconnection\u201d. Neuroimage 49, 2995\u20133004 (2010).","journal-title":"Neuroimage"},{"key":"BFnrneurol2014178_CR100","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/s11682-011-9121-8","volume":"5","author":"I Bohanna","year":"2011","unstructured":"Bohanna, I. et al. Diffusion tensor imaging in Huntington's disease reveals distinct patterns of white matter degeneration associated with motor and cognitive deficits. Brain Imaging Behav. 5, 171\u2013180 (2011).","journal-title":"Brain Imaging Behav."},{"key":"BFnrneurol2014178_CR101","doi-asserted-by":"publisher","first-page":"11606","DOI":"10.1073\/pnas.1221536110","volume":"110","author":"M Lehmann","year":"2013","unstructured":"Lehmann, M. et al. Intrinsic connectivity networks in healthy subjects explain clinical variability in Alzheimer's disease. Proc. Natl Acad. Sci. USA 110, 11606\u201311611 (2013).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR102","doi-asserted-by":"publisher","first-page":"2978","DOI":"10.1002\/hbm.22379","volume":"35","author":"N Gour","year":"2014","unstructured":"Gour, N. et al. Functional connectivity changes differ in early and late-onset Alzheimer's disease. Hum. Brain Mapp. 35, 2978\u20132994 (2014).","journal-title":"Hum. Brain Mapp."},{"key":"BFnrneurol2014178_CR103","doi-asserted-by":"publisher","first-page":"2331","DOI":"10.1016\/j.neurobiolaging.2013.03.026","volume":"34","author":"E Canu","year":"2013","unstructured":"Canu, E. et al. White matter microstructural damage in Alzheimer's disease at different ages of onset. Neurobiol. Aging 34, 2331\u20132340 (2013).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR104","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1016\/j.cortex.2011.10.002","volume":"48","author":"R Migliaccio","year":"2012","unstructured":"Migliaccio, R. et al. Brain networks in posterior cortical atrophy: a single case tractography study and literature review. Cortex 48, 1298\u20131309 (2012).","journal-title":"Cortex"},{"key":"BFnrneurol2014178_CR105","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1136\/jnnp.2008.153148","volume":"80","author":"T Duning","year":"2009","unstructured":"Duning, T. et al. Pattern and progression of white-matter changes in a case of posterior cortical atrophy using diffusion tensor imaging. J. Neurol. Neurosurg. Psychiatry 80, 432\u2013436 (2009).","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"BFnrneurol2014178_CR106","doi-asserted-by":"publisher","first-page":"2705","DOI":"10.1093\/cercor\/bhr288","volume":"22","author":"F Agosta","year":"2012","unstructured":"Agosta, F. et al. White matter damage in frontotemporal lobar degeneration spectrum. Cereb. Cortex 22, 2705\u20132714 (2012).","journal-title":"Cereb. Cortex"},{"key":"BFnrneurol2014178_CR107","doi-asserted-by":"publisher","first-page":"431","DOI":"10.3233\/JAD-2012-121156","volume":"33","author":"Y Zhang","year":"2013","unstructured":"Zhang, Y. et al. MRI signatures of brain macrostructural atrophy and microstructural degradation in frontotemporal lobar degeneration subtypes. J. Alzheimers Dis. 33, 431\u2013444 (2013).","journal-title":"J. Alzheimers Dis."},{"key":"BFnrneurol2014178_CR108","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1212\/WNL.0b013e3181d9edde","volume":"74","author":"JL Whitwell","year":"2010","unstructured":"Whitwell, J. L. et al. Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia. Neurology 74, 1279\u20131287 (2010).","journal-title":"Neurology"},{"key":"BFnrneurol2014178_CR109","doi-asserted-by":"publisher","first-page":"e43993","DOI":"10.1371\/journal.pone.0043993","volume":"7","author":"P Lillo","year":"2012","unstructured":"Lillo, P. et al. Grey and white matter changes across the amyotrophic lateral sclerosis-frontotemporal dementia continuum. PLoS ONE 7, e43993 (2012).","journal-title":"PLoS ONE"},{"key":"BFnrneurol2014178_CR110","doi-asserted-by":"publisher","first-page":"2532","DOI":"10.1007\/s00415-013-7012-1","volume":"260","author":"V Rajagopalan","year":"2013","unstructured":"Rajagopalan, V., Yue, G. H. & Pioro, E. P. Brain white matter diffusion tensor metrics from clinical 1.5 T MRI distinguish between ALS phenotypes. J. Neurol. 260, 2532\u20132540 (2013).","journal-title":"J. Neurol."},{"key":"BFnrneurol2014178_CR111","doi-asserted-by":"publisher","first-page":"2817","DOI":"10.1016\/j.neurobiolaging.2012.02.002","volume":"33","author":"F Agosta","year":"2012","unstructured":"Agosta, F. et al. Diffusion tensor MRI contributes to differentiate Richardson's syndrome from PSP-parkinsonism. Neurobiol. Aging 33, 2817\u20132826 (2012).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR112","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1016\/S1474-4422(13)70194-7","volume":"12","author":"SJ Vos","year":"2013","unstructured":"Vos, S. J. et al. Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study. Lancet Neurol. 12, 957\u2013965 (2013).","journal-title":"Lancet Neurol."},{"key":"BFnrneurol2014178_CR113","doi-asserted-by":"publisher","first-page":"12686","DOI":"10.1523\/JNEUROSCI.3189-09.2009","volume":"29","author":"T Hedden","year":"2009","unstructured":"Hedden, T. et al. Disruption of functional connectivity in clinically normal older adults harboring amyloid burden. J. Neurosci. 29, 12686\u201312694 (2009).","journal-title":"J. Neurosci."},{"key":"BFnrneurol2014178_CR114","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1016\/j.biopsych.2009.08.024","volume":"67","author":"YI Sheline","year":"2010","unstructured":"Sheline, Y. I. et al. Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly. Biol. Psychiatry 67, 584\u2013587 (2010).","journal-title":"Biol. Psychiatry"},{"key":"BFnrneurol2014178_CR115","doi-asserted-by":"publisher","first-page":"1635","DOI":"10.1093\/brain\/awr066","volume":"134","author":"A Drzezga","year":"2011","unstructured":"Drzezga, A. et al. Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden. Brain 134, 1635\u20131646 (2011).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR116","doi-asserted-by":"publisher","first-page":"1242","DOI":"10.1001\/jamaneurol.2013.2934","volume":"70","author":"L Wang","year":"2013","unstructured":"Wang, L. et al. Cerebrospinal fluid A\u03b242, phosphorylated Tau181, and resting-state functional connectivity. JAMA Neurol. 70, 1242\u20131248 (2013).","journal-title":"JAMA Neurol."},{"key":"BFnrneurol2014178_CR117","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.neurobiolaging.2013.10.081","volume":"35","author":"MR Brier","year":"2014","unstructured":"Brier, M. R. et al. Functional connectivity and graph theory in preclinical Alzheimer's disease. Neurobiol. Aging 35, 757\u2013768 (2014).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR118","doi-asserted-by":"publisher","first-page":"1977","DOI":"10.1073\/pnas.90.5.1977","volume":"90","author":"WJ Strittmatter","year":"1993","unstructured":"Strittmatter, W. J. et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl Acad. Sci. USA 90, 1977\u20131981 (1993).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR119","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1001\/archneurol.2011.108","volume":"68","author":"MM Machulda","year":"2011","unstructured":"Machulda, M. M. et al. Effect of APOE \u03b54 status on intrinsic network connectivity in cognitively normal elderly subjects. Arch. Neurol. 68, 1131\u20131136 (2011).","journal-title":"Arch. Neurol."},{"key":"BFnrneurol2014178_CR120","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1007\/s11682-012-9187-y","volume":"7","author":"KT Patel","year":"2013","unstructured":"Patel, K. T. et al. Default mode network activity and white matter integrity in healthy middle-aged ApoE4 carriers. Brain Imaging Behav. 7, 60\u201367 (2013).","journal-title":"Brain Imaging Behav."},{"key":"BFnrneurol2014178_CR121","doi-asserted-by":"publisher","first-page":"20760","DOI":"10.1073\/pnas.1109038108","volume":"108","author":"JA Brown","year":"2011","unstructured":"Brown, J. A. et al. Brain network local interconnectivity loss in aging APOE-4 allele carriers. Proc. Natl Acad. Sci. USA 108, 20760\u201320765 (2011).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR122","doi-asserted-by":"publisher","first-page":"553","DOI":"10.3233\/JAD-2009-1163","volume":"18","author":"RA Honea","year":"2009","unstructured":"Honea, R. A., Vidoni, E., Harsha, A. & Burns, J. M. Impact of APOE on the healthy aging brain: a voxel-based MRI and DTI study. J. Alzheimers Dis. 18, 553\u2013564 (2009).","journal-title":"J. Alzheimers Dis."},{"key":"BFnrneurol2014178_CR123","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.3174\/ajnr.A2984","volume":"33","author":"GC Chiang","year":"2012","unstructured":"Chiang, G. C., Zhan, W., Schuff, N. & Weiner, M. W. White matter alterations in cognitively normal apoE \u03b52 carriers: insight into Alzheimer resistance? AJNR Am. J. Neuroradiol. 33, 1392\u20131397 (2012).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"BFnrneurol2014178_CR124","doi-asserted-by":"publisher","first-page":"17035","DOI":"10.1523\/JNEUROSCI.3987-10.2010","volume":"30","author":"YI Sheline","year":"2010","unstructured":"Sheline, Y. I. et al. APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF A\u03b242. J. Neurosci. 30, 17035\u201317040 (2010).","journal-title":"J. Neurosci."},{"key":"BFnrneurol2014178_CR125","doi-asserted-by":"publisher","first-page":"7209","DOI":"10.1073\/pnas.0811879106","volume":"106","author":"N Filippini","year":"2009","unstructured":"Filippini, N. et al. Distinct patterns of brain activity in young carriers of the APOE-\u03b54 allele. Proc. Natl Acad. Sci. USA 106, 7209\u20137214 (2009).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR126","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.jalz.2009.07.003","volume":"6","author":"NA Dennis","year":"2010","unstructured":"Dennis, N. A. et al. Temporal lobe functional activity and connectivity in young adult APOE e4 carriers. Alzheimers Dement. 6, 303\u2013311 (2010).","journal-title":"Alzheimers Dement."},{"key":"BFnrneurol2014178_CR127","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1002\/nbm.2912","volume":"26","author":"NG Dowell","year":"2013","unstructured":"Dowell, N. G. et al. MRI of carriers of the apolipoprotein E e4 allele-evidence for structural differences in normal-appearing brain tissue in e4+ relative to e4\u2212 young adults. NMR Biomed. 26, 674\u2013682 (2013).","journal-title":"NMR Biomed."},{"key":"BFnrneurol2014178_CR128","doi-asserted-by":"publisher","first-page":"e36024","DOI":"10.1371\/journal.pone.0036024","volume":"7","author":"L O'Dwyer","year":"2012","unstructured":"O'Dwyer, L. et al. White matter differences between healthy young ApoE4 carriers and non-carriers identified with tractography and support vector machines. PLoS ONE 7, e36024 (2012).","journal-title":"PLoS ONE"},{"key":"BFnrneurol2014178_CR129","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1001\/jamaneurol.2013.4544","volume":"71","author":"DC Dean","year":"2014","unstructured":"Dean, D. C. et al. Brain differences in infants at differential genetic risk for late-onset Alzheimer disease: a cross-sectional imaging study. JAMA Neurol. 71, 11\u201322 (2014).","journal-title":"JAMA Neurol."},{"key":"BFnrneurol2014178_CR130","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1136\/jnnp-2012-304418","volume":"84","author":"CT McMillan","year":"2013","unstructured":"McMillan, C. T. et al. White matter imaging helps dissociate tau from TDP-43 in frontotemporal lobar degeneration. J. Neurol. Neurosurg. Psychiatry 84, 949\u2013955 (2013).","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"BFnrneurol2014178_CR131","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.1016\/j.neurobiolaging.2013.11.029","volume":"35","author":"CT McMillan","year":"2014","unstructured":"McMillan, C. T. et al. Genetic and neuroanatomic associations in sporadic frontotemporal lobar degeneration. Neurobiol. Aging 35, 1473\u20131482 (2014).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR132","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1001\/jamaneurol.2013.4835","volume":"71","author":"E Premi","year":"2014","unstructured":"Premi, E. et al. Effect of TMEM106B polymorphism on functional network connectivity in asymptomatic GRN mutation carriers. JAMA Neurol. 71, 216\u2013221 (2014).","journal-title":"JAMA Neurol."},{"key":"BFnrneurol2014178_CR133","doi-asserted-by":"publisher","first-page":"165","DOI":"10.3233\/JAD-130062","volume":"36","author":"R Sala-Llonch","year":"2013","unstructured":"Sala-Llonch, R. et al. Evolving brain functional abnormalities in PSEN1 mutation carriers: a resting and visual encoding fMRI study. J. Alzheimers Dis. 36, 165\u2013175 (2013).","journal-title":"J. Alzheimers Dis."},{"key":"BFnrneurol2014178_CR134","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1212\/WNL.0b013e3182a1aafe","volume":"81","author":"JP Chhatwal","year":"2013","unstructured":"Chhatwal, J. P. et al. Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology 81, 736\u2013744 (2013).","journal-title":"Neurology"},{"key":"BFnrneurol2014178_CR135","doi-asserted-by":"publisher","first-page":"2506","DOI":"10.1016\/j.neurobiolaging.2011.10.031","volume":"33","author":"B Borroni","year":"2012","unstructured":"Borroni, B. et al. Granulin mutation drives brain damage and reorganization from preclinical to symptomatic FTLD. Neurobiol. Aging 33, 2506\u20132520 (2012).","journal-title":"Neurobiol. Aging"},{"key":"BFnrneurol2014178_CR136","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1212\/WNL.0b013e31828407bc","volume":"80","author":"EG Dopper","year":"2013","unstructured":"Dopper, E. G. et al. Structural and functional brain connectivity in presymptomatic familial frontotemporal dementia. Neurology 80, 814\u2013823 (2013).","journal-title":"Neurology"},{"key":"BFnrneurol2014178_CR137","doi-asserted-by":"publisher","unstructured":"Pievani, M. et al. Pattern of structural and functional brain abnormalities in asymptomatic granulin mutation carriers. Alzheimers Dement. http:\/\/dx.doi.org\/10.1016\/j.jalz.2013.09.009 .","DOI":"10.1016\/j.jalz.2013.09.009"},{"key":"BFnrneurol2014178_CR138","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.parkreldis.2012.08.011","volume":"19","author":"T Wu","year":"2013","unstructured":"Wu, T. et al. Preclinical and clinical neural network changes in SCA2 parkinsonism. Parkinsonism Relat. Disord. 19, 158\u2013164 (2013).","journal-title":"Parkinsonism Relat. Disord."},{"key":"BFnrneurol2014178_CR139","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.neulet.2012.02.095","volume":"514","author":"PG Unschuld","year":"2012","unstructured":"Unschuld, P. G. et al. Impaired cortico-striatal functional connectivity in prodromal Huntington's disease. Neurosci. Lett. 514, 204\u2013209 (2012).","journal-title":"Neurosci. Lett."},{"key":"BFnrneurol2014178_CR140","doi-asserted-by":"publisher","first-page":"1767","DOI":"10.1093\/brain\/awm102","volume":"130","author":"JM Ringman","year":"2007","unstructured":"Ringman, J. M. et al. Diffusion tensor imaging in preclinical and presymptomatic carriers of familial Alzheimer's disease mutations. Brain 130, 1767\u20131776 (2007).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR141","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1093\/brain\/awt065","volume":"136","author":"NS Ryan","year":"2013","unstructured":"Ryan, N. S. et al. Magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial Alzheimer's disease. Brain 136, 1399\u20131414 (2013).","journal-title":"Brain"},{"key":"BFnrneurol2014178_CR142","doi-asserted-by":"publisher","first-page":"909","DOI":"10.3233\/JAD-2010-100678","volume":"22","author":"J Fortea","year":"2010","unstructured":"Fortea, J. et al. Increased cortical thickness and caudate volume precede atrophy in PSEN1 mutation carriers. J. Alzheimers Dis. 22, 909\u2013922 (2010).","journal-title":"J. Alzheimers Dis."},{"key":"BFnrneurol2014178_CR143","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1089\/rej.2007.0623","volume":"11","author":"B Borroni","year":"2008","unstructured":"Borroni, B. et al. Brain magnetic resonance imaging structural changes in a pedigree of asymptomatic progranulin mutation carriers. Rejuvenation Res. 11, 585\u2013595 (2008).","journal-title":"Rejuvenation Res."},{"key":"BFnrneurol2014178_CR144","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1002\/jmri.21217","volume":"27","author":"MC Ng","year":"2008","unstructured":"Ng, M. C. et al. Abnormal diffusion tensor in nonsymptomatic familial amyotrophic lateral sclerosis with a causative superoxide dismutase 1 mutation. J. Magn. Reson. Imaging 27, 8\u201313 (2008).","journal-title":"J. Magn. Reson. Imaging"},{"key":"BFnrneurol2014178_CR145","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1002\/hbm.21205","volume":"33","author":"EM Dumas","year":"2012","unstructured":"Dumas, E. M. et al. Early changes in white matter pathways of the sensorimotor cortex in premanifest Huntington's disease. Hum. Brain Mapp. 33, 203\u2013212 (2012).","journal-title":"Hum. Brain Mapp."},{"key":"BFnrneurol2014178_CR146","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1002\/mds.20979","volume":"21","author":"HD Rosas","year":"2006","unstructured":"Rosas, H. D. et al. Diffusion tensor imaging in presymptomatic and early Huntington's disease: Selective white matter pathology and its relationship to clinical measures. Mov. Disord. 21, 1317\u20131325 (2006).","journal-title":"Mov. Disord."},{"key":"BFnrneurol2014178_CR147","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.neuron.2012.03.006","volume":"73","author":"JD Warren","year":"2012","unstructured":"Warren, J. D., Rohrer, J. D. & Hardy, J. Disintegrating brain networks: from syndromes to molecular nexopathies. Neuron 73, 1060\u20131062 (2012).","journal-title":"Neuron"},{"key":"BFnrneurol2014178_CR148","unstructured":"Dian Observational Study. Dominantly Inherited Alzheimer Network [online] , (2013)."},{"key":"BFnrneurol2014178_CR149","unstructured":"GENFI: the Genetic Frontotemporal Dementia Initiative. UCL [online] , (2014)."},{"key":"BFnrneurol2014178_CR150","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1007\/s00429-009-0208-6","volume":"213","author":"JS Damoiseaux","year":"2009","unstructured":"Damoiseaux, J. S. & Greicius, M. D. Greater than the sum of its parts: a review of studies combining structural connectivity and resting-state functional connectivity. Brain Struct. Funct. 213, 525\u2013533 (2009).","journal-title":"Brain Struct. Funct."},{"key":"BFnrneurol2014178_CR151","doi-asserted-by":"publisher","first-page":"2035","DOI":"10.1073\/pnas.0811168106","volume":"106","author":"CJ Honey","year":"2009","unstructured":"Honey, C. J. et al. Predicting human resting-state functional connectivity from structural connectivity. Proc. Natl Acad. Sci. USA 106, 2035\u20132040 (2009).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR152","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.jneumeth.2010.01.014","volume":"194","author":"P Hagmann","year":"2010","unstructured":"Hagmann, P. et al. MR connectomics: principles and challenges. J. Neurosci. Methods 194, 34\u201345 (2010).","journal-title":"J. Neurosci. Methods"},{"key":"BFnrneurol2014178_CR153","doi-asserted-by":"publisher","first-page":"14489","DOI":"10.1523\/JNEUROSCI.2128-13.2013","volume":"33","author":"MP van den Heuvel","year":"2013","unstructured":"van den Heuvel, M. P. & Sporns, O. An anatomical substrate for integration among functional networks in human cortex. J. Neurosci. 33, 14489\u201314500 (2013).","journal-title":"J. Neurosci."},{"key":"BFnrneurol2014178_CR154","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1016\/j.neuron.2012.03.004","volume":"73","author":"J Zhou","year":"2012","unstructured":"Zhou, J., Gennatas, E. D., Kramer, J. H., Miller, B. L. & Seeley, W. W. Predicting regional neurodegeneration from the healthy brain functional connectome. Neuron 73, 1216\u20131227 (2012).","journal-title":"Neuron"},{"key":"BFnrneurol2014178_CR155","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1038\/nrn3214","volume":"13","author":"E Bullmore","year":"2012","unstructured":"Bullmore, E. & Sporns, O. The economy of brain network organization. Nat. Rev. Neurosci. 13, 336\u2013349 (2012).","journal-title":"Nat. Rev. Neurosci."},{"key":"BFnrneurol2014178_CR156","doi-asserted-by":"publisher","first-page":"15775","DOI":"10.1523\/JNEUROSCI.3539-11.2011","volume":"31","author":"MP van den Heuvel","year":"2011","unstructured":"van den Heuvel, M. P. & Sporns, O. Rich-club organization of the human connectome. J. Neurosci. 31, 15775\u201315786 (2011).","journal-title":"J. Neurosci."},{"key":"BFnrneurol2014178_CR157","doi-asserted-by":"publisher","first-page":"11372","DOI":"10.1073\/pnas.1203593109","volume":"109","author":"MP van den Heuvel","year":"2012","unstructured":"van den Heuvel, M. P., Kahn, R. S., Go\u00f1i, J. & Sporns, O. High-cost, high-capacity backbone for global brain communication. Proc. Natl Acad. Sci. USA 109, 11372\u201311377 (2012).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFnrneurol2014178_CR158","doi-asserted-by":"publisher","first-page":"2258","DOI":"10.1093\/cercor\/bht064","volume":"24","author":"G Collin","year":"2014","unstructured":"Collin, G., Sporns, O., Mandl, R. C. & van den Heuvel, M. P. Structural and functional aspects relating to cost and benefit of rich club organization in the human cerebral cortex. Cereb. Cortex 24, 2258\u20132267 (2014).","journal-title":"Cereb. Cortex"},{"key":"BFnrneurol2014178_CR159","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1126\/science.278.5337.412","volume":"278","author":"JH Morrison","year":"1997","unstructured":"Morrison, J. H. & Hof, P. R. Life and death of neurons in the aging brain. Science 278, 412\u2013419 (1997).","journal-title":"Science"},{"key":"BFnrneurol2014178_CR160","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1001\/jamapsychiatry.2013.1328","volume":"70","author":"MP van den Heuvel","year":"2013","unstructured":"van den Heuvel, M. P. et al. Abnormal rich club organization and functional brain dynamics in schizophrenia. JAMA Psychiatry 70, 783\u2013792 (2013).","journal-title":"JAMA Psychiatry"},{"key":"BFnrneurol2014178_CR161","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1212\/WNL.0b013e3181f11e35","volume":"75","author":"WT Hu","year":"2010","unstructured":"Hu, W. T. et al. Distinct cerebral perfusion patterns in FTLD and AD. Neurology 75, 881\u2013888 (2010).","journal-title":"Neurology"},{"key":"BFnrneurol2014178_CR162","unstructured":"Arterial spin labelling Initiative in Dementia (AID). COST: European Cooperation in Science and Technology [online] , (2014)."},{"key":"BFnrneurol2014178_CR163","doi-asserted-by":"publisher","first-page":"2142","DOI":"10.1016\/j.neuroimage.2011.10.018","volume":"59","author":"JD Power","year":"2012","unstructured":"Power, J. D., Barnes, K. A., Snyder, A. Z., Schlaggar, B. L. & Petersen, S. E. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage 59, 2142\u20132154 (2012).","journal-title":"Neuroimage"},{"key":"BFnrneurol2014178_CR164","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.neuroimage.2004.05.013","volume":"23","author":"K Uludag\u02d8","year":"2004","unstructured":"Uludag\u02d8, K. et al. Coupling of cerebral blood flow and oxygen consumption during physiological activation and deactivation measured with fMRI. Neuroimage 23, 148\u2013155 (2004).","journal-title":"Neuroimage"},{"key":"BFnrneurol2014178_CR165","doi-asserted-by":"publisher","first-page":"1572","DOI":"10.1016\/j.neuroimage.2009.08.062","volume":"49","author":"LE Danielian","year":"2010","unstructured":"Danielian, L. E., Iwata, N. K., Thomasson, D. M. & Floeter, M. K. Reliability of fiber tracking measurements in diffusion tensor imaging for longitudinal study. Neuroimage 49, 1572\u20131580 (2010).","journal-title":"Neuroimage"},{"key":"BFnrneurol2014178_CR166","doi-asserted-by":"publisher","first-page":"2163","DOI":"10.1016\/j.neuroimage.2009.10.080","volume":"49","author":"XN Zuo","year":"2010","unstructured":"Zuo, X. N. et al. Reliable intrinsic connectivity networks: test-retest evaluation using ICA and dual regression approach. Neuroimage 49, 2163\u20132177 (2010).","journal-title":"Neuroimage"},{"key":"BFnrneurol2014178_CR167","doi-asserted-by":"publisher","first-page":"1761","DOI":"10.1212\/WNL.0b013e31825830bd","volume":"78","author":"CT McMillan","year":"2012","unstructured":"McMillan, C. T. et al. White matter imaging contributes to the multimodal diagnosis of frontotemporal lobar degeneration. Neurology 78, 1761\u20131768 (2012).","journal-title":"Neurology"}],"container-title":["Nature Reviews Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nrneurol.2014.178.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrneurol.2014.178","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrneurol.2014.178.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T14:37:38Z","timestamp":1717425458000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nrneurol.2014.178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,7]]},"references-count":167,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["BFnrneurol2014178"],"URL":"https:\/\/doi.org\/10.1038\/nrneurol.2014.178","relation":{},"ISSN":["1759-4758","1759-4766"],"issn-type":[{"value":"1759-4758","type":"print"},{"value":"1759-4766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,7]]},"assertion":[{"value":"7 October 2014","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"G.B.F. has served on the advisory boards for Lilly, BMS, Bayer, Lundbeck, Elan, AstraZeneca, Pfizer, Baxter, Taurx and Wyeth, and has received research support from Wyeth, Lilly and Lundbeck Italia. The other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}