{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:39:42Z","timestamp":1740155982850,"version":"3.37.3"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2015,12,31]],"date-time":"2015-12-31T00:00:00Z","timestamp":1451520000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Rev Urol"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1038\/nrurol.2015.303","type":"journal-article","created":{"date-parts":[[2015,12,31]],"date-time":"2015-12-31T12:14:00Z","timestamp":1451564040000},"page":"69-70","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Novel findings continue to challenge researchers and clinicians"],"prefix":"10.1038","volume":"13","author":[{"given":"Rose","family":"Khavari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Boone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,12,31]]},"reference":[{"key":"BFnrurol2015303_CR1","doi-asserted-by":"publisher","unstructured":"Koeck, I., Burkhard, F. C. & Monastyrskaya, K. Activation of common signaling pathways during remodeling of the heart and the bladder. Biochem. Pharmacol. \n                    http:\/\/dx.doi.org\/10.1016\/j.bcp.2015.09.012\n                    \n                   (2015).","DOI":"10.1016\/j.bcp.2015.09.012"},{"key":"BFnrurol2015303_CR2","doi-asserted-by":"publisher","first-page":"1686","DOI":"10.1111\/j.1464-410X.2010.09445.x","volume":"106","author":"PD Metcalfe","year":"2010","unstructured":"Metcalfe, P. D.  et al. Bladder outlet obstruction: progression from inflammation to fibrosis. BJU Int. 106, 1686\u20131694 (2010).","journal-title":"BJU Int."},{"key":"BFnrurol2015303_CR3","doi-asserted-by":"publisher","first-page":"288","DOI":"10.2353\/ajpath.2010.090552","volume":"176","author":"V Sanchez Freire","year":"2010","unstructured":"Sanchez Freire, V.  et al. MicroRNAs may mediate the down-regulation of neurokinin-1 receptor in chronic bladder pain syndrome. Am. J. Pathol. 176, 288\u2013303 (2010).","journal-title":"Am. J. Pathol."},{"key":"BFnrurol2015303_CR4","doi-asserted-by":"publisher","first-page":"e0140250","DOI":"10.1371\/journal.pone.0140250","volume":"10","author":"D Woodworth","year":"2015","unstructured":"Woodworth, D.  et al. Unique microstructural changes in the brain associated with urological chronic pelvic pain syndrome (UCPPS) revealed by diffusion tensor MRI, super-resolution track density imaging, and statistical parameter mapping: a MAPP network neuroimaging study. PLoS ONE 10, e0140250 (2015).","journal-title":"PLoS ONE"},{"key":"BFnrurol2015303_CR5","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.juro.2015.02.082","volume":"194","author":"MA Farmer","year":"2015","unstructured":"Farmer, M. A.  et al. Brain white matter abnormalities in female interstitial cystitis\/bladder pain syndrome: a MAPP network neuroimaging study. J. Urol. 194, 118\u2013126 (2015).","journal-title":"J. Urol."},{"key":"BFnrurol2015303_CR6","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.juro.2014.08.042","volume":"193","author":"AE Kairys","year":"2015","unstructured":"Kairys, A. E.  et al. Increased brain gray matter in the primary somatosensory cortex is associated with increased pain and mood disturbance in patients with interstitial cystitis\/painful bladder syndrome. J. Urol. 193, 131\u2013137 (2015).","journal-title":"J. Urol."},{"key":"BFnrurol2015303_CR7","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1016\/j.juro.2014.03.093","volume":"192","author":"LA Kilpatrick","year":"2014","unstructured":"Kilpatrick, L. A.  et al. Alterations in resting state oscillations and connectivity in sensory and motor networks in women with interstitial cystitis\/painful bladder syndrome. J. Urol. 192, 947\u2013955 (2014).","journal-title":"J. Urol."},{"key":"BFnrurol2015303_CR8","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1001\/jamainternmed.2014.7663","volume":"175","author":"SL Gray","year":"2015","unstructured":"Gray, S. L.  et al. Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study. JAMA Intern. Med. 175, 401\u2013407 (2015).","journal-title":"JAMA Intern. Med."},{"key":"BFnrurol2015303_CR9","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/S0140-6736(14)62337-0","volume":"386","author":"MA Barone","year":"2015","unstructured":"Barone, M. A.  et al. Breakdown of simple female genital fistula repair after 7 day versus 14 day postoperative bladder catheterisation: a randomised, controlled, open-label, non-inferiority trial. Lancet 386, 56\u201362 (2015).","journal-title":"Lancet"},{"key":"BFnrurol2015303_CR10","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1016\/S0140-6736(06)69476-2","volume":"368","author":"LL Wall","year":"2006","unstructured":"Wall, L. L. Obstetric vesicovaginal fistula as an international public-health problem. Lancet 368, 1201\u20131209 (2006).","journal-title":"Lancet"}],"container-title":["Nature Reviews Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nrurol.2015.303.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrurol.2015.303","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nrurol.2015.303.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T04:13:54Z","timestamp":1684469634000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nrurol.2015.303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,31]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["BFnrurol2015303"],"URL":"https:\/\/doi.org\/10.1038\/nrurol.2015.303","relation":{},"ISSN":["1759-4812","1759-4820"],"issn-type":[{"type":"print","value":"1759-4812"},{"type":"electronic","value":"1759-4820"}],"subject":[],"published":{"date-parts":[[2015,12,31]]},"assertion":[{"value":"31 December 2015","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}