{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T23:56:34Z","timestamp":1792454194440,"version":"4.5.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2014,3,23]],"date-time":"2014-03-23T00:00:00Z","timestamp":1395532800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Struct Mol Biol"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1038\/nsmb.2796","type":"journal-article","created":{"date-parts":[[2014,3,23]],"date-time":"2014-03-23T13:18:43Z","timestamp":1395580723000},"page":"366-374","source":"Crossref","is-referenced-by-count":709,"title":["Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks"],"prefix":"10.1038","volume":"21","author":[{"given":"Fran\u00e7ois","family":"Aymard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrix","family":"Bugler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine K","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Guillou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Caron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Briois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason S","family":"Iacovoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Daburon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle M","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen P","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ga\u00eblle","family":"Legube","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,3,23]]},"reference":[{"key":"BFnsmb2796_CR1","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1042\/BJ20090942","volume":"423","author":"AJ Hartlerode","year":"2009","unstructured":"Hartlerode, A.J. & Scully, R. Mechanisms of double-strand break repair in somatic mammalian cells. Biochem. J. 423, 157\u2013168 (2009).","journal-title":"Biochem. J."},{"key":"BFnsmb2796_CR2","doi-asserted-by":"publisher","first-page":"3413","DOI":"10.1038\/emboj.2009.276","volume":"28","author":"A Beucher","year":"2009","unstructured":"Beucher, A. et al. ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2. EMBO J. 28, 3413\u20133427 (2009).","journal-title":"EMBO J."},{"key":"BFnsmb2796_CR3","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1038\/ncb2017","volume":"12","author":"AT Noon","year":"2010","unstructured":"Noon, A.T. et al. 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nat. Cell Biol. 12, 177\u2013184 (2010).","journal-title":"Nat. Cell Biol."},{"key":"BFnsmb2796_CR4","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1038\/emboj.2011.27","volume":"30","author":"A Shibata","year":"2011","unstructured":"Shibata, A. et al. Factors determining DNA double-strand break repair pathway choice in G2 phase. EMBO J. 30, 1079\u20131092 (2011).","journal-title":"EMBO J."},{"key":"BFnsmb2796_CR5","doi-asserted-by":"publisher","first-page":"e1000855","DOI":"10.1371\/journal.pgen.1000855","volume":"6","author":"F Fattah","year":"2010","unstructured":"Fattah, F. et al. Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells. PLoS Genet. 6, e1000855 (2010).","journal-title":"PLoS Genet."},{"key":"BFnsmb2796_CR6","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.molcel.2011.03.019","volume":"42","author":"A Bothmer","year":"2011","unstructured":"Bothmer, A. et al. Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1. Mol. Cell 42, 319\u2013329 (2011).","journal-title":"Mol. Cell"},{"key":"BFnsmb2796_CR7","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1038\/nsmb.1831","volume":"17","author":"P Bouwman","year":"2010","unstructured":"Bouwman, P. et al. 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat. Struct. Mol. Biol. 17, 688\u2013695 (2010).","journal-title":"Nat. Struct. Mol. Biol."},{"key":"BFnsmb2796_CR8","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.cell.2010.03.012","volume":"141","author":"SF Bunting","year":"2010","unstructured":"Bunting, S.F. et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 141, 243\u2013254 (2010).","journal-title":"Cell"},{"key":"BFnsmb2796_CR9","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1016\/j.molcel.2013.01.002","volume":"49","author":"JR Chapman","year":"2013","unstructured":"Chapman, J.R. et al. RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Mol. Cell 49, 858\u2013871 (2013).","journal-title":"Mol. Cell"},{"key":"BFnsmb2796_CR10","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1126\/science.1230624","volume":"339","author":"M Di Virgilio","year":"2013","unstructured":"Di Virgilio, M. et al. Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching. Science 339, 711\u2013715 (2013).","journal-title":"Science"},{"key":"BFnsmb2796_CR11","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1016\/j.molcel.2013.01.001","volume":"49","author":"C Escribano-D\u00edaz","year":"2013","unstructured":"Escribano-D\u00edaz, C. et al. A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice. Mol. Cell 49, 872\u2013883 (2013).","journal-title":"Mol. Cell"},{"key":"BFnsmb2796_CR12","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1126\/science.1231573","volume":"339","author":"M Zimmermann","year":"2013","unstructured":"Zimmermann, M., Lottersberger, F., Buonomo, S.B., Sfeir, A. & de Lange, T. 53BP1 regulates DSB repair using Rif1 to control 5\u2032 end resection. Science 339, 700\u2013704 (2013).","journal-title":"Science"},{"key":"BFnsmb2796_CR13","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/nature06337","volume":"450","author":"AA Sartori","year":"2007","unstructured":"Sartori, A.A. et al. Human CtIP promotes DNA end resection. Nature 450, 509\u2013514 (2007).","journal-title":"Nature"},{"key":"BFnsmb2796_CR14","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.molcel.2013.11.003","volume":"53","author":"A Shibata","year":"2014","unstructured":"Shibata, A. et al. DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Mol. Cell 53, 7\u201318 (2014).","journal-title":"Mol. Cell"},{"key":"BFnsmb2796_CR15","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.1016\/j.cell.2006.10.043","volume":"127","author":"MV Botuyan","year":"2006","unstructured":"Botuyan, M.V. et al. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 127, 1361\u20131373 (2006).","journal-title":"Cell"},{"key":"BFnsmb2796_CR16","doi-asserted-by":"publisher","first-page":"e49211","DOI":"10.1371\/journal.pone.0049211","volume":"7","author":"AJ Hartlerode","year":"2012","unstructured":"Hartlerode, A.J. et al. Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks. PLoS ONE 7, e49211 (2012).","journal-title":"PLoS ONE"},{"key":"BFnsmb2796_CR17","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1016\/j.molcel.2010.10.011","volume":"40","author":"H Oda","year":"2010","unstructured":"Oda, H. et al. Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage. Mol. Cell 40, 364\u2013376 (2010).","journal-title":"Mol. Cell"},{"key":"BFnsmb2796_CR18","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1038\/nature09658","volume":"470","author":"H Pei","year":"2011","unstructured":"Pei, H. et al. MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature 470, 124\u2013128 (2011).","journal-title":"Nature"},{"key":"BFnsmb2796_CR19","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1016\/j.cell.2004.11.009","volume":"119","author":"SL Sanders","year":"2004","unstructured":"Sanders, S.L. et al. Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell 119, 603\u2013614 (2004).","journal-title":"Cell"},{"key":"BFnsmb2796_CR20","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1038\/nsmb.2499","volume":"20","author":"J Tang","year":"2013","unstructured":"Tang, J. et al. Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nat. Struct. Mol. Biol. 20, 317\u2013325 (2013).","journal-title":"Nat. Struct. Mol. Biol."},{"key":"BFnsmb2796_CR21","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1042\/BST0370897","volume":"37","author":"JE FitzGerald","year":"2009","unstructured":"FitzGerald, J.E., Grenon, M. & Lowndes, N.F. 53BP1: function and mechanisms of focal recruitment. Biochem. Soc. Trans. 37, 897\u2013904 (2009).","journal-title":"Biochem. Soc. Trans."},{"key":"BFnsmb2796_CR22","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1016\/j.cell.2011.02.012","volume":"144","author":"I Chiolo","year":"2011","unstructured":"Chiolo, I. et al. Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair. Cell 144, 732\u2013744 (2011).","journal-title":"Cell"},{"key":"BFnsmb2796_CR23","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1038\/ncb1599","volume":"9","author":"E Berkovich","year":"2007","unstructured":"Berkovich, E., Monnat, R.J. Jr. & Kastan, M.B. Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair. Nat. Cell Biol. 9, 683\u2013690 (2007).","journal-title":"Nat. Cell Biol."},{"key":"BFnsmb2796_CR24","doi-asserted-by":"publisher","first-page":"6064","DOI":"10.1073\/pnas.91.13.6064","volume":"91","author":"P Rouet","year":"1994","unstructured":"Rouet, P., Smih, F. & Jasin, M. Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. Proc. Natl. Acad. Sci. USA 91, 6064\u20136068 (1994).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnsmb2796_CR25","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1042\/BST20110747","volume":"40","author":"KM Miller","year":"2012","unstructured":"Miller, K.M. & Jackson, S.P. Histone marks: repairing DNA breaks within the context of chromatin. Biochem. Soc. Trans. 40, 370\u2013376 (2012).","journal-title":"Biochem. Soc. Trans."},{"key":"BFnsmb2796_CR26","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1016\/j.molcel.2012.06.002","volume":"46","author":"G Soria","year":"2012","unstructured":"Soria, G., Polo, S.E. & Almouzni, G. Prime, repair, restore: the active role of chromatin in the DNA damage response. Mol. Cell 46, 722\u2013734 (2012).","journal-title":"Mol. Cell"},{"key":"BFnsmb2796_CR27","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/S1097-2765(03)00242-9","volume":"12","author":"B Wolner","year":"2003","unstructured":"Wolner, B., van Komen, S., Sung, P. & Peterson, C.L. Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast. Mol. Cell 12, 221\u2013232 (2003).","journal-title":"Mol. Cell"},{"key":"BFnsmb2796_CR28","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1016\/j.cell.2010.04.038","volume":"141","author":"NM Shanbhag","year":"2010","unstructured":"Shanbhag, N.M., Rafalska-Metcalf, I.U., Balane-Bolivar, C., Janicki, S.M. & Greenberg, R.A. ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 141, 970\u2013981 (2010).","journal-title":"Cell"},{"key":"BFnsmb2796_CR29","doi-asserted-by":"publisher","first-page":"e1002460","DOI":"10.1371\/journal.pgen.1002460","volume":"8","author":"P Caron","year":"2012","unstructured":"Caron, P. et al. Cohesin protects genes against \u03b3H2AX Induced by DNA double-strand breaks. PLoS Genet. 8, e1002460 (2012).","journal-title":"PLoS Genet."},{"key":"BFnsmb2796_CR30","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1038\/emboj.2010.38","volume":"29","author":"JS Iacovoni","year":"2010","unstructured":"Iacovoni, J.S. et al. High-resolution profiling of \u03b3H2AX around DNA double strand breaks in the mammalian genome. EMBO J. 29, 1446\u20131457 (2010).","journal-title":"EMBO J."},{"key":"BFnsmb2796_CR31","doi-asserted-by":"publisher","first-page":"2963","DOI":"10.4161\/cc.9.15.12412","volume":"9","author":"L Massip","year":"2010","unstructured":"Massip, L., Caron, P., Iacovoni, J.S., Trouche, D. & Legube, G. Deciphering the chromatin landscape induced around DNA double strand breaks. Cell Cycle 9, 2963\u20132972 (2010).","journal-title":"Cell Cycle"},{"key":"BFnsmb2796_CR32","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1038\/nprot.2014.031","volume":"9","author":"C Chailleux","year":"2014","unstructured":"Chailleux, C. et al. Quantifying DNA double-strand breaks induced by site-specific endonucleases in living cells by ligation-mediated purification. Nat. Protoc. 9, 517\u2013528 (2014).","journal-title":"Nat. Protoc."},{"key":"BFnsmb2796_CR33","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1038\/nmeth.1401","volume":"6","author":"K Nishimura","year":"2009","unstructured":"Nishimura, K., Fukagawa, T., Takisawa, H., Kakimoto, T. & Kanemaki, M. An auxin-based degron system for the rapid depletion of proteins in nonplant cells. Nat. Methods 6, 917\u2013922 (2009).","journal-title":"Nat. Methods"},{"key":"BFnsmb2796_CR34","doi-asserted-by":"crossref","unstructured":"ENCODE Project Consortium. A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol. 9, e1001046 (2011).","DOI":"10.1371\/journal.pbio.1001046"},{"key":"BFnsmb2796_CR35","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1038\/nbt.2517","volume":"31","author":"Y Kim","year":"2013","unstructured":"Kim, Y. et al. A library of TAL effector nucleases spanning the human genome. Nat. Biotechnol. 31, 251\u2013258 (2013).","journal-title":"Nat. Biotechnol."},{"key":"BFnsmb2796_CR36","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1038\/nsmb.2314","volume":"19","author":"M Daugaard","year":"2012","unstructured":"Daugaard, M. et al. LEDGF (p75) promotes DNA-end resection and homologous recombination. Nat. Struct. Mol. Biol. 19, 803\u2013810 (2012).","journal-title":"Nat. Struct. Mol. Biol."},{"key":"BFnsmb2796_CR37","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1038\/nsmb.2370","volume":"19","author":"JS Butler","year":"2012","unstructured":"Butler, J.S. & Dent, S.Y. Chromatin 'resetting' during transcription elongation: a central role for methylated H3K36. Nat. Struct. Mol. Biol. 19, 863\u2013864 (2012).","journal-title":"Nat. Struct. Mol. Biol."},{"key":"BFnsmb2796_CR38","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1038\/sj.emboj.7601967","volume":"27","author":"JW Edmunds","year":"2008","unstructured":"Edmunds, J.W., Mahadevan, L.C. & Clayton, A.L. Dynamic histone H3 methylation during gene induction: HYPB\/Setd2 mediates all H3K36 trimethylation. EMBO J. 27, 406\u2013420 (2008).","journal-title":"EMBO J."},{"key":"BFnsmb2796_CR39","doi-asserted-by":"publisher","first-page":"3196","DOI":"10.1038\/sj.onc.1209344","volume":"25","author":"A Dumay","year":"2006","unstructured":"Dumay, A. et al. Bax and Bid, two proapoptotic Bcl-2 family members, inhibit homologous recombination, independently of apoptosis regulation. Oncogene 25, 3196\u20133205 (2006).","journal-title":"Oncogene"},{"key":"BFnsmb2796_CR40","doi-asserted-by":"publisher","first-page":"9558","DOI":"10.1074\/jbc.M808906200","volume":"284","author":"P Huertas","year":"2009","unstructured":"Huertas, P. & Jackson, S.P. Human CtIP mediates cell cycle control of DNA end resection and double strand break repair. J. Biol. Chem. 284, 9558\u20139565 (2009).","journal-title":"J. Biol. Chem."},{"key":"BFnsmb2796_CR41","doi-asserted-by":"publisher","first-page":"9478","DOI":"10.1128\/MCB.24.21.9478-9486.2004","volume":"24","author":"X Yu","year":"2004","unstructured":"Yu, X. & Chen, J. DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains. Mol. Cell. Biol. 24, 9478\u20139486 (2004).","journal-title":"Mol. Cell. Biol."},{"key":"BFnsmb2796_CR42","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.molcel.2012.05.052","volume":"47","author":"K Karanam","year":"2012","unstructured":"Karanam, K., Kafri, R., Loewer, A. & Lahav, G. Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase. Mol. Cell 47, 320\u2013329 (2012).","journal-title":"Mol. Cell"},{"key":"BFnsmb2796_CR43","doi-asserted-by":"publisher","first-page":"9454","DOI":"10.1073\/pnas.1205759109","volume":"109","author":"M Gandhi","year":"2012","unstructured":"Gandhi, M. et al. Homologous chromosomes make contact at the sites of double-strand breaks in genes in somatic G0\/G1-phase human cells. Proc. Natl. Acad. Sci. USA 109, 9454\u20139459 (2012).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnsmb2796_CR44","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1016\/j.dnarep.2010.09.013","volume":"9","author":"AA Goodarzi","year":"2010","unstructured":"Goodarzi, A.A., Jeggo, P. & Lobrich, M. The influence of heterochromatin on DNA double strand break repair: getting the strong, silent type to relax. DNA Repair (Amst.) 9, 1273\u20131282 (2010).","journal-title":"DNA Repair (Amst.)"},{"key":"BFnsmb2796_CR45","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1101\/gr.118091.110","volume":"21","author":"S Chantalat","year":"2011","unstructured":"Chantalat, S. et al. Histone H3 trimethylation at lysine 36 is associated with constitutive and facultative heterochromatin. Genome Res. 21, 1426\u20131437 (2011).","journal-title":"Genome Res."},{"key":"BFnsmb2796_CR46","doi-asserted-by":"publisher","first-page":"R630","DOI":"10.1016\/j.cub.2011.07.029","volume":"21","author":"DJ Finnegan","year":"2011","unstructured":"Finnegan, D.J. Oogenesis: active heterochromatin. Curr. Biol. 21, R630\u2013R632 (2011).","journal-title":"Curr. Biol."},{"key":"BFnsmb2796_CR47","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/j.ceb.2011.03.005","volume":"23","author":"E Lejeune","year":"2011","unstructured":"Lejeune, E. & Allshire, R.C. Common ground: small RNA programming and chromatin modifications. Curr. Opin. Cell Biol. 23, 258\u2013265 (2011).","journal-title":"Curr. Opin. Cell Biol."},{"key":"BFnsmb2796_CR48","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.tig.2011.02.002","volume":"27","author":"AV Probst","year":"2011","unstructured":"Probst, A.V. & Almouzni, G. Heterochromatin establishment in the context of genome-wide epigenetic reprogramming. Trends Genet. 27, 177\u2013185 (2011).","journal-title":"Trends Genet."},{"key":"BFnsmb2796_CR49","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1038\/nature09906","volume":"473","author":"J Ernst","year":"2011","unstructured":"Ernst, J. et al. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473, 43\u201349 (2011).","journal-title":"Nature"},{"key":"BFnsmb2796_CR50","doi-asserted-by":"publisher","first-page":"26114","DOI":"10.1074\/jbc.M109.089433","volume":"285","author":"A Dhayalan","year":"2010","unstructured":"Dhayalan, A. et al. The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation. J. Biol. Chem. 285, 26114\u201326120 (2010).","journal-title":"J. Biol. Chem."},{"key":"BFnsmb2796_CR51","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1038\/nsmb.1797","volume":"17","author":"A Vezzoli","year":"2010","unstructured":"Vezzoli, A. et al. Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1. Nat. Struct. Mol. Biol. 17, 617\u2013619 (2010).","journal-title":"Nat. Struct. Mol. Biol."},{"key":"BFnsmb2796_CR52","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1038\/nsmb.1899","volume":"17","author":"KM Miller","year":"2010","unstructured":"Miller, K.M. et al. Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. Nat. Struct. Mol. Biol. 17, 1144\u20131151 (2010).","journal-title":"Nat. Struct. Mol. Biol."}],"container-title":["Nature Structural &amp; Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nsmb.2796.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nsmb.2796","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nsmb.2796.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T00:36:09Z","timestamp":1684456569000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nsmb.2796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,23]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["BFnsmb2796"],"URL":"https:\/\/doi.org\/10.1038\/nsmb.2796","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718321312.793493797","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.718321312.793494515","asserted-by":"object"}]},"ISSN":["1545-9993","1545-9985"],"issn-type":[{"value":"1545-9993","type":"print"},{"value":"1545-9985","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,23]]}}}