{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T12:05:03Z","timestamp":1790078703846,"version":"4.0.1"},"reference-count":69,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2016,4,25]],"date-time":"2016-04-25T00:00:00Z","timestamp":1461542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Struct Mol Biol"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1038\/nsmb.3210","type":"journal-article","created":{"date-parts":[[2016,4,25]],"date-time":"2016-04-25T15:00:09Z","timestamp":1461596409000},"page":"513-521","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":82,"title":["Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV"],"prefix":"10.1038","volume":"23","author":[{"given":"Kathryn M","family":"Hastie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Igonet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian M","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2431-2255","authenticated-orcid":false,"given":"Pierre","family":"Legrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle A","family":"Zandonatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert F","family":"Garry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e9lix A","family":"Rey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B","family":"Oldstone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica Ollmann","family":"Saphire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,4,25]]},"reference":[{"key":"BFnsmb3210_CR1","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1002\/jmv.1890380107","volume":"38","author":"CB Stephensen","year":"1992","unstructured":"Stephensen, C.B. et al. Prevalence of serum antibodies against lymphocytic choriomeningitis virus in selected populations from two U.S. cities. J. Med. Virol. 38, 27\u201331 (1992).","journal-title":"J. Med. Virol."},{"key":"BFnsmb3210_CR2","doi-asserted-by":"publisher","first-page":"117","DOI":"10.4269\/ajtmh.1991.44.117","volume":"44","author":"JE Childs","year":"1991","unstructured":"Childs, J.E. et al. Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population. Am. J. Trop. Med. Hyg. 44, 117\u2013121 (1991).","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"BFnsmb3210_CR3","doi-asserted-by":"publisher","first-page":"381","DOI":"10.4269\/ajtmh.1994.50.381","volume":"50","author":"AM Ambrosio","year":"1994","unstructured":"Ambrosio, A.M., Feuillade, M.R., Gamboa, G.S. & Maiztegui, J.I. Prevalence of lymphocytic choriomeningitis virus infection in a human population of Argentina. Am. J. Trop. Med. Hyg. 50, 381\u2013386 (1994).","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"BFnsmb3210_CR4","doi-asserted-by":"publisher","first-page":"47","DOI":"10.4269\/ajtmh.1998.58.47","volume":"58","author":"TJ Marrie","year":"1998","unstructured":"Marrie, T.J. & Saron, M.F. Seroprevalence of lymphocytic choriomeningitis virus in Nova Scotia. Am. J. Trop. Med. Hyg. 58, 47\u201349 (1998).","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"BFnsmb3210_CR5","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1002\/jmv.10389","volume":"70","author":"L Lled\u00f3","year":"2003","unstructured":"Lled\u00f3, L., Geg\u00fandez, M.I., Saz, J.V., Bahamontes, N. & Beltr\u00e1n, M. Lymphocytic choriomeningitis virus infection in a province of Spain: analysis of sera from the general population and wild rodents. J. Med. Virol. 70, 273\u2013275 (2003).","journal-title":"J. Med. Virol."},{"key":"BFnsmb3210_CR6","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1002\/jmv.20357","volume":"76","author":"L Riera","year":"2005","unstructured":"Riera, L. et al. Serological study of the lymphochoriomeningitis virus (LCMV) in an inner city of Argentina. J. Med. Virol. 76, 285\u2013289 (2005).","journal-title":"J. Med. Virol."},{"key":"BFnsmb3210_CR7","unstructured":"Buchmeier, M., de la Torre, J.C. & Peters, C.J. Arenaviridae: the Viruses and their Replication (Lippincott-Raven, 2007)."},{"key":"BFnsmb3210_CR8","doi-asserted-by":"publisher","first-page":"2235","DOI":"10.1056\/NEJMoa053240","volume":"354","author":"SA Fischer","year":"2006","unstructured":"Fischer, S.A. et al. Transmission of lymphocytic choriomeningitis virus by organ transplantation. N. Engl. J. Med. 354, 2235\u20132249 (2006).","journal-title":"N. Engl. J. Med."},{"key":"BFnsmb3210_CR9","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1016\/j.ajog.2005.11.040","volume":"194","author":"DJ Jamieson","year":"2006","unstructured":"Jamieson, D.J., Kourtis, A.P., Bell, M. & Rasmussen, S.A. Lymphocytic choriomeningitis virus: an emerging obstetric pathogen? Am. J. Obstet. Gynecol. 194, 1532\u20131536 (2006).","journal-title":"Am. J. Obstet. Gynecol."},{"key":"BFnsmb3210_CR10","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.2307\/4581290","volume":"49","author":"C Armstrong","year":"1934","unstructured":"Armstrong, C. & Lillie, R.D. Experimental lymphocytic choriomeningitis of monkeys and mice produced by a virus encountered in studies of the 1933 St. Louis epidemic. Public Health Rep. 49, 1019\u20131027 (1934).","journal-title":"Public Health Rep."},{"key":"BFnsmb3210_CR11","doi-asserted-by":"publisher","first-page":"4180","DOI":"10.1073\/pnas.1222025110","volume":"110","author":"MB Oldstone","year":"2013","unstructured":"Oldstone, M.B. Lessons learned and concepts formed from study of the pathogenesis of the two negative-strand viruses lymphocytic choriomeningitis and influenza. Proc. Natl. Acad. Sci. USA 110, 4180\u20134183 (2013).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnsmb3210_CR12","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.it.2015.02.008","volume":"36","author":"KE Pauken","year":"2015","unstructured":"Pauken, K.E. & Wherry, E.J. Overcoming T cell exhaustion in infection and cancer. Trends Immunol. 36, 265\u2013276 (2015).","journal-title":"Trends Immunol."},{"key":"BFnsmb3210_CR13","first-page":"1","volume":"263","author":"RM Zinkernagel","year":"2002","unstructured":"Zinkernagel, R.M. Lymphocytic choriomeningitis virus and immunology. Curr. Top. Microbiol. Immunol. 263, 1\u20135 (2002).","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"BFnsmb3210_CR14","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.smim.2004.08.013","volume":"16","author":"TS Gourley","year":"2004","unstructured":"Gourley, T.S., Wherry, E.J., Masopust, D. & Ahmed, R. Generation and maintenance of immunological memory. Semin. Immunol. 16, 323\u2013333 (2004).","journal-title":"Semin. Immunol."},{"key":"BFnsmb3210_CR15","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1038\/sj.embor.7400002","volume":"4","author":"R Eichler","year":"2003","unstructured":"Eichler, R. et al. Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor. EMBO Rep. 4, 1084\u20131088 (2003).","journal-title":"EMBO Rep."},{"key":"BFnsmb3210_CR16","doi-asserted-by":"publisher","first-page":"10783","DOI":"10.1128\/JVI.78.19.10783-10792.2004","volume":"78","author":"J York","year":"2004","unstructured":"York, J., Romanowski, V., Lu, M. & Nunberg, J.H. The signal peptide of the Jun\u00edn arenavirus envelope glycoprotein is myristoylated and forms an essential subunit of the mature G1-G2 complex. J. Virol. 78, 10783\u201310792 (2004).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR17","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/S0014-5793(03)00160-1","volume":"538","author":"R Eichler","year":"2003","unstructured":"Eichler, R., Lenz, O., Strecker, T. & Garten, W. Signal peptide of Lassa virus glycoprotein GP-C exhibits an unusual length. FEBS Lett. 538, 203\u2013206 (2003).","journal-title":"FEBS Lett."},{"key":"BFnsmb3210_CR18","doi-asserted-by":"publisher","first-page":"41914","DOI":"10.1074\/jbc.M302343200","volume":"278","author":"M Froeschke","year":"2003","unstructured":"Froeschke, M., Basler, M., Groettrup, M. & Dobberstein, B. Long-lived signal peptide of lymphocytic choriomeningitis virus glycoprotein pGP-C. J. Biol. Chem. 278, 41914\u201341920 (2003).","journal-title":"J. Biol. Chem."},{"key":"BFnsmb3210_CR19","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/S0042-6822(03)00421-5","volume":"314","author":"S Kunz","year":"2003","unstructured":"Kunz, S., Edelmann, K.H., de la Torre, J.C., Gorney, R. & Oldstone, M.B. Mechanisms for lymphocytic choriomeningitis virus glycoprotein cleavage, transport, and incorporation into virions. Virology 314, 168\u2013178 (2003).","journal-title":"Virology"},{"key":"BFnsmb3210_CR20","doi-asserted-by":"publisher","first-page":"5649","DOI":"10.1128\/JVI.02759-06","volume":"81","author":"AA Saunders","year":"2007","unstructured":"Saunders, A.A. et al. Mapping the landscape of the lymphocytic choriomeningitis virus stable signal peptide reveals novel functional domains. J. Virol. 81, 5649\u20135657 (2007).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR21","doi-asserted-by":"publisher","first-page":"12515","DOI":"10.1128\/JVI.01481-07","volume":"81","author":"S Schrempf","year":"2007","unstructured":"Schrempf, S., Froeschke, M., Giroglou, T., von Laer, D. & Dobberstein, B. Signal peptide requirements for lymphocytic choriomeningitis virus glycoprotein C maturation and virus infectivity. J. Virol. 81, 12515\u201312524 (2007).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR22","doi-asserted-by":"publisher","first-page":"7775","DOI":"10.1128\/JVI.00642-06","volume":"80","author":"J York","year":"2006","unstructured":"York, J. & Nunberg, J.H. Role of the stable signal peptide of Jun\u00edn arenavirus envelope glycoprotein in pH-dependent membrane fusion. J. Virol. 80, 7775\u20137780 (2006).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR23","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.virol.2006.08.048","volume":"359","author":"J York","year":"2007","unstructured":"York, J. & Nunberg, J.H. Distinct requirements for signal peptidase processing and function in the stable signal peptide subunit of the Jun\u00edn virus envelope glycoprotein. Virology 359, 72\u201381 (2007).","journal-title":"Virology"},{"key":"BFnsmb3210_CR24","doi-asserted-by":"publisher","first-page":"2079","DOI":"10.1126\/science.282.5396.2079","volume":"282","author":"W Cao","year":"1998","unstructured":"Cao, W. et al. Identification of alpha-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus. Science 282, 2079\u20132081 (1998).","journal-title":"Science"},{"key":"BFnsmb3210_CR25","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1126\/science.1214115","volume":"335","author":"K Inamori","year":"2012","unstructured":"Inamori, K. et al. Dystroglycan function requires xylosyl- and glucuronyltransferase activities of LARGE. Science 335, 93\u201396 (2012).","journal-title":"Science"},{"key":"BFnsmb3210_CR26","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1016\/j.cell.2004.06.003","volume":"117","author":"M Kanagawa","year":"2004","unstructured":"Kanagawa, M. et al. Molecular recognition by LARGE is essential for expression of functional dystroglycan. Cell 117, 953\u2013964 (2004).","journal-title":"Cell"},{"key":"BFnsmb3210_CR27","doi-asserted-by":"publisher","first-page":"14282","DOI":"10.1128\/JVI.79.22.14282-14296.2005","volume":"79","author":"S Kunz","year":"2005","unstructured":"Kunz, S. et al. Posttranslational modification of alpha-dystroglycan, the cellular receptor for arenaviruses, by the glycosyltransferase LARGE is critical for virus binding. J. Virol. 79, 14282\u201314296 (2005).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR28","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1126\/science.1252480","volume":"344","author":"LT Jae","year":"2014","unstructured":"Jae, L.T. et al. Lassa virus entry requires a trigger-induced receptor switch. Science 344, 1506\u20131510 (2014).","journal-title":"Science"},{"key":"BFnsmb3210_CR29","doi-asserted-by":"publisher","first-page":"5140","DOI":"10.1128\/JVI.76.10.5140-5146.2002","volume":"76","author":"CF Spiropoulou","year":"2002","unstructured":"Spiropoulou, C.F., Kunz, S., Rollin, P.E., Campbell, K.P. & Oldstone, M.B. New World arenavirus clade C, but not clade A and B viruses, utilizes alpha-dystroglycan as its major receptor. J. Virol. 76, 5140\u20135146 (2002).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR30","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1128\/JVI.01397-07","volume":"82","author":"ML Flanagan","year":"2008","unstructured":"Flanagan, M.L. et al. New world clade B arenaviruses can use transferrin receptor 1 (TfR1)-dependent and -independent entry pathways, and glycoproteins from human pathogenic strains are associated with the use of TfR1. J. Virol. 82, 938\u2013948 (2008).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR31","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/nature05539","volume":"446","author":"SR Radoshitzky","year":"2007","unstructured":"Radoshitzky, S.R. et al. Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses. Nature 446, 92\u201396 (2007).","journal-title":"Nature"},{"key":"BFnsmb3210_CR32","doi-asserted-by":"publisher","first-page":"5897","DOI":"10.1128\/JVI.00008-06","volume":"80","author":"B Eschli","year":"2006","unstructured":"Eschli, B. et al. Identification of an N-terminal trimeric coiled-coil core within arenavirus glycoprotein 2 permits assignment to class I viral fusion proteins. J. Virol. 80, 5897\u20135907 (2006).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR33","doi-asserted-by":"publisher","first-page":"19967","DOI":"10.1073\/pnas.1108910108","volume":"108","author":"S Igonet","year":"2011","unstructured":"Igonet, S. et al. X-ray structure of the arenavirus glycoprotein GP2 in its postfusion hairpin conformation. Proc. Natl. Acad. Sci. USA 108, 19967\u201319972 (2011).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnsmb3210_CR34","doi-asserted-by":"publisher","first-page":"13070","DOI":"10.1128\/JVI.02298-13","volume":"87","author":"ML Parsy","year":"2013","unstructured":"Parsy, M.L., Harlos, K., Huiskonen, J.T. & Bowden, T.A. Crystal structure of Venezuelan hemorrhagic fever virus fusion glycoprotein reveals a class 1 postfusion architecture with extensive glycosylation. J. Virol. 87, 13070\u201313075 (2013).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR35","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1038\/nsmb.1772","volume":"17","author":"J Abraham","year":"2010","unstructured":"Abraham, J., Corbett, K.D., Farzan, M., Choe, H. & Harrison, S.C. Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses. Nat. Struct. Mol. Biol. 17, 438\u2013444 (2010).","journal-title":"Nat. Struct. Mol. Biol."},{"key":"BFnsmb3210_CR36","doi-asserted-by":"publisher","first-page":"8259","DOI":"10.1128\/JVI.00761-09","volume":"83","author":"TA Bowden","year":"2009","unstructured":"Bowden, T.A. et al. Unusual molecular architecture of the machupo virus attachment glycoprotein. J. Virol. 83, 8259\u20138265 (2009).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR37","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.chom.2015.11.005","volume":"18","author":"S Mahmutovic","year":"2015","unstructured":"Mahmutovic, S. et al. Molecular basis for antibody-mediated neutralization of New World hemorrhagic fever mammarenaviruses. Cell Host Microbe 18, 705\u2013713 (2015).","journal-title":"Cell Host Microbe"},{"key":"BFnsmb3210_CR38","doi-asserted-by":"publisher","first-page":"7584","DOI":"10.1128\/JVI.00651-15","volume":"89","author":"H Cohen-Dvashi","year":"2015","unstructured":"Cohen-Dvashi, H., Cohen, N., Israeli, H. & Diskin, R. Molecular mechanism for LAMP1 recognition by Lassa virus. J. Virol. 89, 7584\u20137592 (2015).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR39","doi-asserted-by":"publisher","first-page":"2320","DOI":"10.1099\/vir.0.82950-0","volume":"88","author":"C Klewitz","year":"2007","unstructured":"Klewitz, C., Klenk, H.D. & ter Meulen, J. Amino acids from both N-terminal hydrophobic regions of the Lassa virus envelope glycoprotein GP-2 are critical for pH-dependent membrane fusion and infectivity. J. Gen. Virol. 88, 2320\u20132328 (2007).","journal-title":"J. Gen. Virol."},{"key":"BFnsmb3210_CR40","doi-asserted-by":"publisher","first-page":"16672","DOI":"10.1073\/pnas.1213802109","volume":"109","author":"BD Welch","year":"2012","unstructured":"Welch, B.D. et al. Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proc. Natl. Acad. Sci. USA 109, 16672\u201316677 (2012).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnsmb3210_CR41","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1038\/375291a0","volume":"375","author":"FA Rey","year":"1995","unstructured":"Rey, F.A., Heinz, F.X., Mandl, C., Kunz, C. & Harrison, S.C. The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution. Nature 375, 291\u2013298 (1995).","journal-title":"Nature"},{"key":"BFnsmb3210_CR42","doi-asserted-by":"publisher","first-page":"11000","DOI":"10.1128\/JVI.01735-06","volume":"80","author":"R Kanai","year":"2006","unstructured":"Kanai, R. et al. Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes. J. Virol. 80, 11000\u201311008 (2006).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR43","doi-asserted-by":"publisher","first-page":"6986","DOI":"10.1073\/pnas.0832193100","volume":"100","author":"Y Modis","year":"2003","unstructured":"Modis, Y., Ogata, S., Clements, D. & Harrison, S.C. A ligand-binding pocket in the dengue virus envelope glycoprotein. Proc. Natl. Acad. Sci. USA 100, 6986\u20136991 (2003).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnsmb3210_CR44","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1128\/JVI.79.2.1223-1231.2005","volume":"79","author":"Y Modis","year":"2005","unstructured":"Modis, Y., Ogata, S., Clements, D. & Harrison, S.C. Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein. J. Virol. 79, 1223\u20131231 (2005).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR45","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1016\/j.virol.2004.05.009","volume":"325","author":"S Kunz","year":"2004","unstructured":"Kunz, S., Sevilla, N., Rojek, J.M. & Oldstone, M.B. Use of alternative receptors different than alpha-dystroglycan by selected isolates of lymphocytic choriomeningitis virus. Virology 325, 432\u2013445 (2004).","journal-title":"Virology"},{"key":"BFnsmb3210_CR46","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.virol.2010.11.023","volume":"411","author":"MB Oldstone","year":"2011","unstructured":"Oldstone, M.B. & Campbell, K.P. Decoding arenavirus pathogenesis: essential roles for alpha-dystroglycan-virus interactions and the immune response. Virology 411, 170\u2013179 (2011).","journal-title":"Virology"},{"key":"BFnsmb3210_CR47","first-page":"83","volume":"263","author":"MBA Oldstone","year":"2002","unstructured":"Oldstone, M.B.A. Biology and pathogenesis of lymphocytic choriomeningitis virus infection. Curr. Top. Microbiol. Immunol. 263, 83\u2013117 (2002).","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"BFnsmb3210_CR48","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1084\/jem.192.9.1249","volume":"192","author":"N Sevilla","year":"2000","unstructured":"Sevilla, N. et al. Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells. J. Exp. Med. 192, 1249\u20131260 (2000).","journal-title":"J. Exp. Med."},{"key":"BFnsmb3210_CR49","doi-asserted-by":"publisher","first-page":"2969","DOI":"10.1073\/pnas.1019304108","volume":"108","author":"BM Sullivan","year":"2011","unstructured":"Sullivan, B.M. et al. Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence. Proc. Natl. Acad. Sci. USA 108, 2969\u20132974 (2011).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnsmb3210_CR50","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1128\/JVI.75.1.448-457.2001","volume":"75","author":"SC Smelt","year":"2001","unstructured":"Smelt, S.C. et al. Differences in affinity of binding of lymphocytic choriomeningitis virus strains to the cellular receptor alpha-dystroglycan correlate with viral tropism and disease kinetics. J. Virol. 75, 448\u2013457 (2001).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR51","doi-asserted-by":"crossref","first-page":"8438","DOI":"10.1128\/JVI.70.12.8438-8443.1996","volume":"70","author":"MN Teng","year":"1996","unstructured":"Teng, M.N., Borrow, P., Oldstone, M.B. & de la Torre, J.C. A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome. J. Virol. 70, 8438\u20138443 (1996).","journal-title":"J. Virol."},{"key":"BFnsmb3210_CR52","doi-asserted-by":"publisher","first-page":"e1005418","DOI":"10.1371\/journal.ppat.1005418","volume":"12","author":"S Li","year":"2016","unstructured":"Li, S. et al. Acidic pH-induced conformations and LAMP1 binding of the Lassa virus glycoprotein spike. PLoS Pathog. 12, e1005418 (2016).","journal-title":"PLoS Pathog."},{"key":"BFnsmb3210_CR53","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/0042-6822(91)90991-J","volume":"183","author":"JW Burns","year":"1991","unstructured":"Burns, J.W. & Buchmeier, M.J. Protein-protein interactions in lymphocytic choriomeningitis virus. Virology 183, 620\u2013629 (1991).","journal-title":"Virology"},{"key":"BFnsmb3210_CR54","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1038\/nrmicro1067","volume":"3","author":"S Mukhopadhyay","year":"2005","unstructured":"Mukhopadhyay, S., Kuhn, R.J. & Rossmann, M.G. A structural perspective of the flavivirus life cycle. Nat. Rev. Microbiol. 3, 13\u201322 (2005).","journal-title":"Nat. Rev. Microbiol."},{"key":"BFnsmb3210_CR55","doi-asserted-by":"publisher","first-page":"10037","DOI":"10.1073\/pnas.181342398","volume":"98","author":"NA Baker","year":"2001","unstructured":"Baker, N.A., Sept, D., Joseph, S., Holst, M.J. & McCammon, J.A. Electrostatics of nanosystems: application to microtubules and the ribosome. Proc. Natl. Acad. Sci. USA 98, 10037\u201310041 (2001).","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BFnsmb3210_CR56","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1107\/S0907444909047337","volume":"66","author":"W Kabsch","year":"2010","unstructured":"Kabsch, W. Xds. Acta Crystallogr. D Biol. Crystallogr. 66, 125\u2013132 (2010).","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"BFnsmb3210_CR57","first-page":"215","volume":"364","author":"C Vonrhein","year":"2007","unstructured":"Vonrhein, C., Blanc, E., Roversi, P. & Bricogne, G. Automated structure solution with autoSHARP. Methods Mol. Biol. 364, 215\u2013230 (2007).","journal-title":"Methods Mol. Biol."},{"key":"BFnsmb3210_CR58","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1107\/S0907444906022116","volume":"62","author":"K Cowtan","year":"2006","unstructured":"Cowtan, K. The Buccaneer software for automated model building. 1. Tracing protein chains. Acta Crystallogr. D Biol. Crystallogr. 62, 1002\u20131011 (2006).","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"BFnsmb3210_CR59","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1107\/S0907444911039655","volume":"68","author":"K Cowtan","year":"2012","unstructured":"Cowtan, K. Completion of autobuilt protein models using a database of protein fragments. Acta Crystallogr. D Biol. Crystallogr. 68, 328\u2013335 (2012).","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"BFnsmb3210_CR60","doi-asserted-by":"publisher","first-page":"2126","DOI":"10.1107\/S0907444904019158","volume":"60","author":"P Emsley","year":"2004","unstructured":"Emsley, P. & Cowtan, K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D Biol. Crystallogr. 60, 2126\u20132132 (2004).","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"BFnsmb3210_CR61","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1107\/S0907444909052925","volume":"66","author":"PD Adams","year":"2010","unstructured":"Adams, P.D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D Biol. Crystallogr. 66, 213\u2013221 (2010).","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"BFnsmb3210_CR62","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1006\/abio.1996.0345","volume":"240","author":"J Wen","year":"1996","unstructured":"Wen, J., Arakawa, T. & Philo, J.S. Size-exclusion chromatography with on-line light-scattering, absorbance, and refractive index detectors for studying proteins and their interactions. Anal. Biochem. 240, 155\u2013166 (1996).","journal-title":"Anal. Biochem."},{"key":"BFnsmb3210_CR63","first-page":"97","volume":"328","author":"E Folta-Stogniew","year":"2006","unstructured":"Folta-Stogniew, E. Oligomeric states of proteins determined by size-exclusion chromatography coupled with light scattering, absorbance, and refractive index detectors. Methods Mol. Biol. 328, 97\u2013112 (2006).","journal-title":"Methods Mol. Biol."},{"key":"BFnsmb3210_CR64","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/j.virol.2006.01.012","volume":"350","author":"AB S\u00e1nchez","year":"2006","unstructured":"S\u00e1nchez, A.B. & de la Torre, J.C. Rescue of the prototypic Arenavirus LCMV entirely from plasmid. Virology 350, 370\u2013380 (2006).","journal-title":"Virology"},{"key":"BFnsmb3210_CR65","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.virol.2004.04.044","volume":"325","author":"S Kunz","year":"2004","unstructured":"Kunz, S., Calder, L. & Oldstone, M.B. Electron microscopy of an alpha-dystroglycan fragment containing receptor sites for lymphocytic choriomeningitis virus and laminin, and use of the receptoid body as a reagent to neutralize virus. Virology 325, 207\u2013215 (2004).","journal-title":"Virology"},{"key":"BFnsmb3210_CR66","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1083\/jcb.200104103","volume":"155","author":"S Kunz","year":"2001","unstructured":"Kunz, S., Sevilla, N., McGavern, D.B., Campbell, K.P. & Oldstone, M.B. Molecular analysis of the interaction of LCMV with its cellular receptor \u03b1-dystroglycan. J. Cell Biol. 155, 301\u2013310 (2001).","journal-title":"J. Cell Biol."},{"key":"BFnsmb3210_CR67","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/0042-6822(86)90020-6","volume":"153","author":"BS Parekh","year":"1986","unstructured":"Parekh, B.S. & Buchmeier, M.J. Proteins of lymphocytic choriomeningitis virus: antigenic topography of the viral glycoproteins. Virology 153, 168\u2013178 (1986).","journal-title":"Virology"},{"key":"BFnsmb3210_CR68","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/0042-6822(83)90135-6","volume":"130","author":"M Bruns","year":"1983","unstructured":"Bruns, M., Cihak, J., M\u00fcller, G. & Lehmann-Grube, F. Lymphocytic choriomeningitis virus. VI. Isolation of a glycoprotein mediating neutralization. Virology 130, 247\u2013251 (1983).","journal-title":"Virology"},{"key":"BFnsmb3210_CR69","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/0166-0934(91)90018-U","volume":"33","author":"M Battegay","year":"1991","unstructured":"Battegay, M. et al. Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates. J. Virol. Methods 33, 191\u2013198 (1991).","journal-title":"J. Virol. Methods"}],"container-title":["Nature Structural &amp; Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/nsmb.3210.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nsmb.3210","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/nsmb.3210.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T04:39:43Z","timestamp":1684471183000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/nsmb.3210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,25]]},"references-count":69,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["BFnsmb3210"],"URL":"https:\/\/doi.org\/10.1038\/nsmb.3210","relation":{},"ISSN":["1545-9993","1545-9985"],"issn-type":[{"value":"1545-9993","type":"print"},{"value":"1545-9985","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,25]]},"assertion":[{"value":"16 October 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 March 2016","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 April 2016","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}