{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T07:31:47Z","timestamp":1774683107857,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,9,6]],"date-time":"2012-09-06T00:00:00Z","timestamp":1346889600000},"content-version":"vor","delay-in-days":3781,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obesity Research"],"published-print":{"date-parts":[[2002,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective:<\/jats:italic> To investigate the relationships between visceral obesity and hepatic steatosis in obese patients undergoing adjustable silicone gastric banding with the LAP\u2010BAND.<\/jats:p><jats:p><jats:italic>Research Methods and Procedures:<\/jats:italic> Six premenopausal, morbidly obese women with an ultrasonographic diagnosis of liver steatosis were evaluated before surgery and 8 and 24 weeks after surgery. Liver volume and body fat distribution were simultaneously analyzed by total\u2010body multislices magnetic resonance imaging.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> Before surgery, the only variable found to be correlated with liver volume was visceral adipose tissue volume (<jats:italic>r<\/jats:italic> = 0.91; <jats:italic>p<\/jats:italic> &lt; 0.01). Weight loss was 9.9 \u00b1 3.8 kg in the period from 0 to 8 weeks (<jats:italic>p<\/jats:italic> &lt; 0.01) and 7.1 \u00b1 4.9 kg in the the period from 8 to 24 weeks (<jats:italic>p<\/jats:italic> &lt; 0.05). Total fat showed a statistically significant reduction of 6.2 \u00b1 4.0 liters in the 0\u2010 to 8\u2010week period and a further significant reduction of 7.7 \u00b1 3.9 liters in the 8\u2010 to 24\u2010week period. Visceral adipose tissue showed a statistically significant reduction of 1.0 \u00b1 0.9 liters in the 0\u2010 to 8\u2010week period (<jats:italic>p<\/jats:italic> &lt; 0.05) but only a further, not significant reduction of 0.6 \u00b1 0.7 liters in the 8\u2010 to 24\u2010week period. The relative reduction of visceral fat in the 0\u2010to 8\u2010week period was higher than the relative reduction of total fat. Liver volume also showed a statistically significant reduction of 0.24 \u00b1 0.26 liters in the first phase of weight loss (<jats:italic>p<\/jats:italic> &lt; 0.05), corresponding to a relative reduction of 12.3 \u00b1 10.6%. During the 8\u2010 to 24\u2010week period, liver volume was substantially stable.<\/jats:p><jats:p><jats:italic>Discussion:<\/jats:italic> Hepatomegaly was associated with visceral obesity in morbidly obese women with liver steatosis. In the phase of rapid weight loss after gastric surgery, a preferential mobilization of visceral fat, compared with total adipose tissue, occurred. This preferential visceral fat loss was associated with a significant reduction in liver volume.<\/jats:p>","DOI":"10.1038\/oby.2002.56","type":"journal-article","created":{"date-parts":[[2008,4,16]],"date-time":"2008-04-16T12:19:09Z","timestamp":1208348349000},"page":"408-411","source":"Crossref","is-referenced-by-count":84,"title":["Liver Volume and Visceral Obesity in Women with Hepatic Steatosis Undergoing Gastric Banding"],"prefix":"10.1002","volume":"10","author":[{"given":"Luca","family":"Busetto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Tregnaghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"de Marchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianni","family":"Segato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirto","family":"Foletto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Sergi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franco","family":"Favretti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Lise","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuliano","family":"Enzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,6]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.14.12.1132"},{"key":"e_1_2_6_3_2","first-page":"98","article-title":"Non\u2010alcoholic steatohepatitis: association with obesity and insulin resistance, and influence of weight loss","volume":"26","author":"Luyckx F. h.","year":"2000","journal-title":"Diabetes Metab"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.84.5.5661"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/92.2.73"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.292.6512.13"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0801086"},{"key":"e_1_2_6_8_2","first-page":"1","article-title":"Laparoscopic adjustable silicone gastric banding: technique and results","volume":"5","author":"Favretti F.","year":"1995","journal-title":"Obes Surg"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1992.72.2.787"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(90)91169-7"},{"key":"e_1_2_6_11_2","first-page":"G1849","article-title":"Tissue triglycerides, insulin resistance, and insulin production: implications for hyperinsulinemia of obesity","volume":"193","author":"Koyama K.","year":"1997","journal-title":"Am J Physio Gastrointest Liv Physiol"},{"key":"e_1_2_6_12_2","first-page":"841","article-title":"The influence of fatty liver on insulin clearance and insulin resistance in non\u2010diabetic Japanese subjects","volume":"19","author":"Goto T.","year":"1995","journal-title":"Int J Obes Relat Metab Disord"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0801508"}],"container-title":["Obesity Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Foby.2002.56","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/oby.2002.56","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T09:02:38Z","timestamp":1698742958000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/oby.2002.56"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,5]]}},"alternative-id":["10.1038\/oby.2002.56"],"URL":"https:\/\/doi.org\/10.1038\/oby.2002.56","archive":["Portico"],"relation":{},"ISSN":["1071-7323","1550-8528"],"issn-type":[{"value":"1071-7323","type":"print"},{"value":"1550-8528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,5]]}}}