{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:34:05Z","timestamp":1761561245544},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2012,9,6]],"date-time":"2012-09-06T00:00:00Z","timestamp":1346889600000},"content-version":"vor","delay-in-days":2136,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective:<\/jats:italic> Pulmonary embolism is a leading cause of death for bariatric patients. Numerous regimens have been proposed, but a comprehensive, simple approach is lacking. This study provides a simple, easily implemented prophylaxis regimen.<\/jats:p><jats:p><jats:italic>Research Methods and Procedures:<\/jats:italic> One hundred fifty bariatric surgery patients were evaluated. Patients considered at high risk for venous thromboembolism had heart failure, a BMI of \u226550 kg\/m<jats:sup>2<\/jats:sup>, or a history of venous thromboembolism or pelvic surgery. Preoperatively and postoperatively, all patients received subcutaneous enoxaparin or unfractionated heparin. High\u2010risk patients received either preoperatively inserted inferior vena cava filters or continuous heparin infusions intraoperatively. All high\u2010risk patients were anticoagulated with warfarin (Coumadin; Bristol Myers\u2010Squibb, Princeton, NJ) for at least 3 months postoperatively. Initially, some patients experienced significant hemorrhage; to prevent this, sutures were oversewn into staple lines.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> No patient experienced venous thromboembolism; a binomial test showed that the regimen reduced the risk of this complication to less than 2% (<jats:italic>p<\/jats:italic> &lt; 0.05). Hemorrhage sufficient to require transfusion occurred in 4 of the first 20 patients; of the remaining 130 patients, into whose staple lines sutures were oversewn, none required transfusion (<jats:italic>p<\/jats:italic> &lt; 0.05).<\/jats:p><jats:p><jats:italic>Discussion:<\/jats:italic> Patients should be divided into those who are at high risk and those who are at low risk for venous thromboembolism. All patients should receive pre\u2010 and postoperative anticoagulation. High\u2010risk patients should also receive either an inferior vena cava filter or intraoperative heparin infusions, as well as at least 3 months of Coumadin therapy. Oversewing of staple lines may reduce the risk of hemorrhage.<\/jats:p>","DOI":"10.1038\/oby.2006.229","type":"journal-article","created":{"date-parts":[[2008,4,23]],"date-time":"2008-04-23T15:21:30Z","timestamp":1208964090000},"page":"1961-1965","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["A Simple Venous Thromboembolism Prophylaxis Protocol for Patients Undergoing Bariatric Surgery"],"prefix":"10.1002","volume":"14","author":[{"given":"Eldo E.","family":"Frezza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell S.","family":"Wachtel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,6]]},"reference":[{"key":"e_1_2_8_2_2","first-page":"391","article-title":"Venous thromboembolism in severe obesity and trauma: a review of literature","volume":"60","author":"Frezza E. 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