{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:59:55Z","timestamp":1792119595379,"version":"4.4.0"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,9,6]],"date-time":"2012-09-06T00:00:00Z","timestamp":1346889600000},"content-version":"vor","delay-in-days":1894,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective:<\/jats:italic>This study assessed the long\u2010term effects of group behavioral treatment plus individual cognitive behavioral therapy (CBT) and\/or fluoxetine in binge eating disorder (BED) patients.<\/jats:p><jats:p><jats:italic>Research Methods and Procedures:<\/jats:italic>A total of 116 individuals were randomized to an initial five\u2010month trial and were followed up over two years. Assessments, including binge frequency, weight, and self\u2010report measures, were administered at pre\u2010treatment, post\u2010treatment, and \u223c6, 12, 18, and 24 months after initial treatment.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic>Across treatment groups, there was overall improvement over 29 months in binge frequency and in binge abstinence. The odds of binge abstinence 2 years post\u2010treatment were 1.373 times the odds of binge abstinence immediately post\u2010treatment. There was no significant change in weight over the two\u2010year period. Subjects who received individual CBT evidenced lower binge frequency over the two\u2010year follow\u2010up period than patients who had not received individual CBT. Similarly, CBT was associated with increased rates of binge abstinence. There were no main effects of treatment assignment on weight over the two\u2010year follow\u2010up period. There was a significant advantage for fluoxetine assignment over the two\u2010year follow\u2010up period on depressive symptoms.<\/jats:p><jats:p><jats:italic>Discussion:<\/jats:italic>The major significance of the study rests in its examination of the long\u2010term effects of standardized interventions for BED. Our findings provide support for the ideas that short\u2010term treatment may confer long\u2010term benefit and that not all treatments are equivalent in the benefits they confer.<\/jats:p>","DOI":"10.1038\/oby.2007.203","type":"journal-article","created":{"date-parts":[[2008,7,17]],"date-time":"2008-07-17T17:18:51Z","timestamp":1216315131000},"page":"1702-1709","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Cognitive Behavioral Therapy and Fluoxetine for Binge Eating Disorder: Two\u2010year Follow\u2010up"],"prefix":"10.1002","volume":"15","author":[{"given":"Michael J.","family":"Devlin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juli A.","family":"Goldfein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Petkova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linxu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. Timothy","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,9,6]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.11.1109"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.2.255"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2005.208"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(97)00262-6"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0800846"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1550-8528.1994.tb00049.x"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.65.2.343"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.59.8.713"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v65n1104"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(97)00263-8"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/eat.1110"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.57.7.659"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2005.126"},{"key":"e_1_2_7_15_2","volume-title":"The LEARN Program for Weight Control","author":"Brownell K. D.","year":"1997"},{"key":"e_1_2_7_16_2","first-page":"361","volume-title":"Binge Eating: Nature, Assessment, and Treatment","author":"Fairburn C. G.","year":"1993"},{"key":"e_1_2_7_17_2","first-page":"317","volume-title":"Binge Eating: Nature, Assessment, and Treatment","author":"Fairburn C. G.","year":"1993"},{"key":"e_1_2_7_18_2","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"1994"},{"key":"e_1_2_7_19_2","volume-title":"Structured Clinical Interview for DSM\u2010IV Axis I Disorders (SCID)","author":"First M. B.","year":"1995"},{"key":"e_1_2_7_20_2","volume-title":"Beck Depression Inventory","author":"Beck A. T.","year":"1996"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/1098-108X(198707)6:4<485::AID-EAT2260060405>3.0.CO;2-O"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4603(82)90024-7"},{"key":"e_1_2_7_23_2","volume-title":"The Brief Symptom Inventory: Administration, Scoring, and Procedures Manual","author":"Derogatis L. R.","year":"1993"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(85)90010-8"},{"key":"e_1_2_7_25_2","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780198524847.001.0001","volume-title":"The Analysis of Longitudinal Data","author":"Diggle P. J.","year":"2002"},{"key":"e_1_2_7_26_2","volume-title":"SAS, version 9","author":"SAS Institute, I. n. c.","year":"2006"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2004.11.002"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/eat.10201"}],"container-title":["Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Foby.2007.203","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/oby.2007.203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T11:26:28Z","timestamp":1709119588000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/oby.2007.203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.1038\/oby.2007.203"],"URL":"https:\/\/doi.org\/10.1038\/oby.2007.203","archive":["Portico"],"relation":{},"ISSN":["1930-7381","1930-739X"],"issn-type":[{"value":"1930-7381","type":"print"},{"value":"1930-739X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7]]},"assertion":[{"value":"2012-09-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}