{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T03:46:00Z","timestamp":1767152760735,"version":"build-2238731810"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,9,6]],"date-time":"2012-09-06T00:00:00Z","timestamp":1346889600000},"content-version":"vor","delay-in-days":1589,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:p>\n                    <jats:bold>Retraction:<\/jats:bold>\n                    Note from the Editor\u2010in\u2010Chief: This paper\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.nature.com\/uidfinder\/10.1038\/oby.2009.88\">is retracted<\/jats:ext-link>\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Objective:<\/jats:bold>\n                    Metabolic syndrome (MS) is on the rise in youth. As high\u2010sensitivity C\u2010reactive protein (hs\u2010CRP) is associated with cardiovascular\/metabolic disorders, we evaluated the association between MS and its components and hs\u2010CRP in a sample of Brazilian overweight and obese youth.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods and Procedures:<\/jats:bold>\n                    A total of 407 students (229 girls, 273 with excessive weight, 11.3 \u00b1 3.2 years) were evaluated. Measurement included BMI, waist circumference (WC), blood pressure, lipids, insulin, and hs\u2010CRP. Excessive weight was defined using BMI\n                    <jats:italic>z<\/jats:italic>\n                    \u2010score; MS by the modified National Cholesterol Education Program\u2014Adult Treatment Panel III.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Subjects were classified into two groups: with MS (\n                    <jats:italic>n<\/jats:italic>\n                    = 72) and without (\n                    <jats:italic>n<\/jats:italic>\n                    = 335). hs\u2010CRP means and medians were higher in MS group (1.41 mg\/l vs. 1.06 mg\/l,\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.001; 2.21 mg\/l vs. 1.23 mg\/l,\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.001). Associations between hs\u2010CRP quartiles and insulin resistance (IR) (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.001), MS (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.001), WC (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.000), BMI\n                    <jats:italic>z<\/jats:italic>\n                    \u2010score (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.001), hypertension (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.001), hypertriglyceridemia (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.001), and low HDL\u2010c (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.023) were significant; adjustment of hs\u2010CRP for BMI\n                    <jats:italic>z<\/jats:italic>\n                    \u2010score eliminated the previous association, except for the number of MS components (nMSc) (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.001). Adjusting for homeostasis model assessment method of IR (HOMA\u2010IR) did not eliminate the relation between hs\u2010CRP and MS components. Furthermore, increases in BMI\n                    <jats:italic>z<\/jats:italic>\n                    \u2010score and nMSc were associated with an increased hs\u2010CRP. Excessive weight (odds ratio (OR), 7.9; confidence interval (CI), 4.7\u201313.4;\n                    <jats:italic>P<\/jats:italic>\n                    = 0.000), hypertension (OR, 2.3; CI, 1.3\u20134.2;\n                    <jats:italic>P<\/jats:italic>\n                    = 0.003), and hypertriglyceridemia (OR, 2.3; CI, 1.5\u20133.7;\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.001) were independently associated with hs\u2010CRP.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Discussion:<\/jats:bold>\n                    In youth, hs\u2010CRP is strongly related with MS and its components, and is also determined by the body composition. This association indicates a precocious proinflammatory state.\n                  <\/jats:p>","DOI":"10.1038\/oby.2008.43","type":"journal-article","created":{"date-parts":[[2008,3,20]],"date-time":"2008-03-20T11:43:18Z","timestamp":1206013398000},"page":"1094-1098","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["RETRACTION: C\u2010reactive Protein and Metabolic Syndrome in Youth: A Strong Relationship?"],"prefix":"10.1002","volume":"16","author":[{"given":"Ant\u00f4nio C.","family":"Oliveira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana M.","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis F.","family":"Adan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nelson F.","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnaluce M.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana M.","family":"Ladeia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,6]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66378-7"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp068182"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa031049"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.2223\/JPED.1052"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.11.010"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.1.42"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc05-2385"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2005.08.025"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0680"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.17.2271"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.s1.06.s43"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.19.2486"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.06.044"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0066-782X2001001500001"},{"issue":"4","key":"e_1_2_7_16_2","first-page":"1","article-title":"IV Diretrizes Brasileiras de Hipertens\u00e3o Arterial","volume":"82","author":"Sociedade Brasileira de Nefrologia","year":"2004","journal-title":"Arq Bras Cardiol"},{"key":"e_1_2_7_17_2","unstructured":"National Health and Nutrition Examination Survey.Anthropometry procedures manual<http:www.cdc.govnchsdatanhanesbm.pdf.2002> (2002). Accessed October2005."},{"key":"e_1_2_7_18_2","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1542\/peds.98.4.649","volume":"98","author":"Update on the 1987 Task Force Report on High Blood Pressure in Children and Adolescents: a working group report from the National High Blood Pressure Education Program. National High Blood Pressure Education Program Working Group on Hypertension Control in Children and Adolescents","year":"1996","journal-title":"Pediatrics"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.6.1487"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-1921"},{"key":"e_1_2_7_21_2","volume-title":"Applied Linear Statistical Models","author":"Neter J.","year":"1996"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.099796"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp068177"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2006.291"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328013dc13"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jhh.1002152"},{"key":"e_1_2_7_27_2","first-page":"722","article-title":"Dyslipidemia among adolescents and children from Pernambuco","volume":"87","author":"Franca E.","year":"2006","journal-title":"Arq Bras Cardiol"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-27302004000600011"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2006.09.039"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05488"},{"key":"e_1_2_7_31_2","unstructured":"International Diabetes Federation.The IDF consensus worldwide definition of the metabolic syndrome<http:www.idf.org> (2005). Accessed 02 August 2005."},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/84.3.505"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.107.1.e13"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.28.4.878"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803035"},{"key":"e_1_2_7_36_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.02.06.dc05-2033"},{"key":"e_1_2_7_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802609"},{"key":"e_1_2_7_38_2","doi-asserted-by":"publisher","DOI":"10.2337\/db06-0116"}],"updated-by":[{"DOI":"10.1038\/oby.2009.88","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"record-id":"3073"}],"container-title":["Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Foby.2008.43","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Foby.2008.43","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/oby.2008.43","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T09:30:34Z","timestamp":1754040634000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1038\/oby.2008.43"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1038\/oby.2008.43"],"URL":"https:\/\/doi.org\/10.1038\/oby.2008.43","archive":["Portico"],"relation":{},"ISSN":["1930-7381","1930-739X"],"issn-type":[{"value":"1930-7381","type":"print"},{"value":"1930-739X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5]]},"assertion":[{"value":"2012-09-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}