{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T06:22:59Z","timestamp":1777702979694,"version":"3.51.4"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"26","license":[{"start":{"date-parts":[[2013,9,9]],"date-time":"2013-09-09T00:00:00Z","timestamp":1378684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2013,9,9]],"date-time":"2013-09-09T00:00:00Z","timestamp":1378684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oncogene"],"published-print":{"date-parts":[[2014,6,26]]},"DOI":"10.1038\/onc.2013.327","type":"journal-article","created":{"date-parts":[[2013,9,9]],"date-time":"2013-09-09T10:14:22Z","timestamp":1378721662000},"page":"3383-3391","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7\u2019s induction of DNA damage response, an activity mediated by E7\u2019s inactivation of pocket proteins"],"prefix":"10.1038","volume":"33","author":[{"given":"J W","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M-K","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P F","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,9,9]]},"reference":[{"key":"BFonc2013327_CR1","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1182\/blood-2002-07-2170","volume":"101","author":"DI Kutler","year":"2003","unstructured":"Kutler DI, Singh B, Satagopan J, Batish SD, Berwick M, Giampietro PF et al. A 20-year perspective on the International Fanconi Anemia Registry (IFAR). Blood 2003; 101: 1249\u20131256.","journal-title":"Blood"},{"key":"BFonc2013327_CR2","doi-asserted-by":"publisher","first-page":"2853","DOI":"10.1016\/j.febslet.2011.04.078","volume":"585","author":"E Garner","year":"2011","unstructured":"Garner E, Smogorzewska A . Ubiquitylation and the Fanconi anemia pathway. FEBS Lett 2011; 585: 2853\u20132860.","journal-title":"FEBS Lett"},{"key":"BFonc2013327_CR3","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1038\/35076590","volume":"2","author":"H Joenje","year":"2001","unstructured":"Joenje H, Patel KJ . The emerging genetic and molecular basis of Fanconi anaemia. Nat Rev Genet 2001; 2: 446\u2013457.","journal-title":"Nat Rev Genet"},{"key":"BFonc2013327_CR4","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1002\/path.3002","volume":"226","author":"GP Crossan","year":"2012","unstructured":"Crossan GP, Patel KJ . The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA. J Pathol 2012; 226: 326\u2013337.","journal-title":"J Pathol"},{"key":"BFonc2013327_CR5","doi-asserted-by":"publisher","first-page":"2925","DOI":"10.1101\/gad.1370505","volume":"19","author":"RD Kennedy","year":"2005","unstructured":"Kennedy RD, D'Andrea AD . The Fanconi Anemia\/BRCA pathway: new faces in the crowd. Genes Dev 2005; 19: 2925\u20132940.","journal-title":"Genes Dev"},{"key":"BFonc2013327_CR6","doi-asserted-by":"publisher","first-page":"1698","DOI":"10.1126\/science.1182372","volume":"326","author":"P Knipscheer","year":"2009","unstructured":"Knipscheer P, Raschle M, Smogorzewska A, Enoiu M, Ho TV, Scharer OD et al. The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair. Science 2009; 326: 1698\u20131701.","journal-title":"Science"},{"key":"BFonc2013327_CR7","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1016\/S0140-6736(07)61416-0","volume":"370","author":"M Schiffman","year":"2007","unstructured":"Schiffman M, Castle PE, Jeronimo J, Rodriguez AC, Wacholder S . Human papillomavirus and cervical cancer. Lancet [Review] 2007; 370: 890\u2013907.","journal-title":"Lancet [Review]"},{"issue":"10 Suppl","key":"BFonc2013327_CR8","doi-asserted-by":"publisher","first-page":"2841","DOI":"10.1002\/cncr.23758","volume":"113","author":"M Watson","year":"2008","unstructured":"Watson M, Saraiya M, Ahmed F, Cardinez CJ, Reichman ME, Weir HK et al. Using population-based cancer registry data to assess the burden of human papillomavirus-associated cancers in the United States: overview of methods. Cancer 2008; 113 (10 Suppl): 2841\u20132854.","journal-title":"Cancer"},{"key":"BFonc2013327_CR9","doi-asserted-by":"publisher","first-page":"5656","DOI":"10.1158\/0008-5472.CAN-08-3711","volume":"69","author":"MK Shin","year":"2009","unstructured":"Shin MK, Balsitis S, Brake T, Lambert PF . Human papillomavirus E7 oncoprotein overrides the tumor suppressor activity of p21Cip1 in cervical carcinogenesis. Cancer Res 2009; 69: 5656\u20135663.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR10","doi-asserted-by":"publisher","first-page":"4099","DOI":"10.1002\/j.1460-2075.1989.tb08594.x","volume":"8","author":"K Munger","year":"1989","unstructured":"Munger K, Werness BA, Dyson N, Phelps WC, Harlow E, Howley PM . Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. EMBO J 1989; 8: 4099\u20134105.","journal-title":"EMBO J"},{"key":"BFonc2013327_CR11","doi-asserted-by":"publisher","first-page":"5418","DOI":"10.1158\/0008-5472.CAN-12-2083","volume":"72","author":"MK Shin","year":"2012","unstructured":"Shin MK, Sage J, Lambert PF . Inactivating all three rb family pocket proteins is insufficient to initiate cervical cancer. Cancer Res 2012; 72: 5418\u20135427.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR12","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1158\/0008-5472.CAN-11-2833","volume":"72","author":"MK Shin","year":"2012","unstructured":"Shin MK, Pitot HC, Lambert PF . Pocket proteins suppress head and neck cancer. Cancer Res 2012; 72: 1280\u20131289.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR13","doi-asserted-by":"publisher","first-page":"9094","DOI":"10.1128\/MCB.23.24.9094-9103.2003","volume":"23","author":"SJ Balsitis","year":"2003","unstructured":"Balsitis SJ, Sage J, Duensing S, Munger K, Jacks T, Lambert PF . Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo. Mol Cell Biol 2003; 23: 9094\u20139103.","journal-title":"Mol Cell Biol"},{"key":"BFonc2013327_CR14","doi-asserted-by":"publisher","first-page":"14769","DOI":"10.1128\/JVI.79.23.14769-14780.2005","volume":"79","author":"AS Collins","year":"2005","unstructured":"Collins AS, Nakahara T, Do A, Lambert PF . Interactions with pocket proteins contribute to the role of human papillomavirus type 16 E7 in the papillomavirus life cycle. J Virol 2005; 79: 14769\u201314780.","journal-title":"J Virol"},{"key":"BFonc2013327_CR15","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/j.virol.2008.10.006","volume":"384","author":"ME McLaughlin-Drubin","year":"2009","unstructured":"McLaughlin-Drubin ME, Munger K . The human papillomavirus E7 oncoprotein. Virology 2009; 384: 335\u2013344.","journal-title":"Virology"},{"key":"BFonc2013327_CR16","doi-asserted-by":"publisher","first-page":"1626","DOI":"10.1158\/0008-5472.CAN-06-3344","volume":"67","author":"A Shai","year":"2007","unstructured":"Shai A, Brake T, Somoza C, Lambert PF . The human papillomavirus E6 oncogene dysregulates the cell cycle and contributes to cervical carcinogenesis through two independent activities. Cancer Res 2007; 67: 1626\u20131635.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR17","doi-asserted-by":"publisher","first-page":"2832","DOI":"10.1128\/JVI.77.5.2832-2842.2003","volume":"77","author":"SM Genther","year":"2003","unstructured":"Genther SM, Sterling S, Duensing S, Munger K, Sattler C, Lambert PF . Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle. J Virol 2003; 77: 2832\u20132842.","journal-title":"J Virol"},{"key":"BFonc2013327_CR18","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1086\/595563","volume":"199","author":"SS Wang","year":"2009","unstructured":"Wang SS, Bratti MC, Rodriguez AC, Herrero R, Burk RD, Porras C et al. Common variants in immune and DNA repair genes and risk for human papillomavirus persistence and progression to cervical cancer. J Infect Dis 2009; 199: 20\u201330.","journal-title":"J Infect Dis"},{"key":"BFonc2013327_CR19","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.ygyno.2011.04.014","volume":"122","author":"I Juko-Pecirep","year":"2011","unstructured":"Juko-Pecirep I, Ivansson EL, Gyllensten UB . Evaluation of Fanconi anaemia genes FANCA, FANCC and FANCL in cervical cancer susceptibility. Gynecol Oncol 2011; 122: 377\u2013381.","journal-title":"Gynecol Oncol"},{"key":"BFonc2013327_CR20","first-page":"7075","volume":"62","author":"S Duensing","year":"2002","unstructured":"Duensing S, Munger K . The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Res 2002; 62: 7075\u20137082.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR21","doi-asserted-by":"publisher","first-page":"13265","DOI":"10.1128\/JVI.01121-07","volume":"81","author":"N Spardy","year":"2007","unstructured":"Spardy N, Duensing A, Charles D, Haines N, Nakahara T, Lambert PF et al. The human papillomavirus type 16 E7 oncoprotein activates the Fanconi anemia (FA) pathway and causes accelerated chromosomal instability in FA cells. J Virol 2007; 81: 13265\u201313270.","journal-title":"J Virol"},{"key":"BFonc2013327_CR22","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1038\/onc.2008.416","volume":"28","author":"EE Hoskins","year":"2009","unstructured":"Hoskins EE, Morris TA, Higginbotham JM, Spardy N, Cha E, Kelly P et al. Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture. Oncogene 2009; 28: 674\u2013685.","journal-title":"Oncogene"},{"key":"BFonc2013327_CR23","doi-asserted-by":"publisher","first-page":"9959","DOI":"10.1158\/0008-5472.CAN-10-1291","volume":"70","author":"JW Park","year":"2010","unstructured":"Park JW, Pitot HC, Strati K, Spardy N, Duensing S, Grompe M et al. Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer. Cancer Res 2010; 70: 9959\u20139968.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR24","first-page":"4862","volume":"63","author":"RR Riley","year":"2003","unstructured":"Riley RR, Duensing S, Brake T, Munger K, Lambert PF, Arbeit JM . Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis. Cancer Res 2003; 63: 4862\u20134871.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR25","doi-asserted-by":"publisher","first-page":"2072","DOI":"10.1182\/blood-2002-11-3597","volume":"101","author":"BP Alter","year":"2003","unstructured":"Alter BP, Greene MH, Velazquez I, Rosenberg PS . Cancer in Fanconi anemia. Blood 2003; 101: 2072.","journal-title":"Blood"},{"key":"BFonc2013327_CR26","doi-asserted-by":"publisher","first-page":"14152","DOI":"10.1073\/pnas.0606698103","volume":"103","author":"K Strati","year":"2006","unstructured":"Strati K, Pitot HC, Lambert PF . Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model. Proc Natl Acad Sci USA 2006; 103: 14152\u201314157.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFonc2013327_CR27","first-page":"8173","volume":"63","author":"T Brake","year":"2003","unstructured":"Brake T, Connor JP, Petereit DG, Lambert PF . Comparative analysis of cervical cancer in women and in a human papillomavirus-transgenic mouse model: identification of minichromosome maintenance protein 7 as an informative biomarker for human cervical cancer. Cancer Res 2003; 63: 8173\u20138180.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR28","doi-asserted-by":"publisher","first-page":"4605","DOI":"10.1158\/0008-5472.CAN-06-3619","volume":"67","author":"D Pyeon","year":"2007","unstructured":"Pyeon D, Newton MA, Lambert PF, den Boon JA, Sengupta S, Marsit CJ et al. Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head\/neck and cervical cancers. Cancer Res 2007; 67: 4605\u20134619.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR29","doi-asserted-by":"publisher","first-page":"5694","DOI":"10.1158\/1078-0432.CCR-05-0587","volume":"11","author":"S Begum","year":"2005","unstructured":"Begum S, Cao D, Gillison M, Zahurak M, Westra WH . Tissue distribution of human papillomavirus 16 DNA integration in patients with tonsillar carcinoma. Clin Cancer Res 2005; 11: 5694\u20135699.","journal-title":"Clin Cancer Res"},{"key":"BFonc2013327_CR30","doi-asserted-by":"publisher","first-page":"1488","DOI":"10.1016\/S0140-6736(04)16194-1","volume":"363","author":"ML Gillison","year":"2004","unstructured":"Gillison ML, Lowy DR . A causal role for human papillomavirus in head and neck cancer. Lancet 2004; 363: 1488\u20131489.","journal-title":"Lancet"},{"key":"BFonc2013327_CR31","doi-asserted-by":"publisher","first-page":"2414","DOI":"10.1182\/blood-2002-01-0278","volume":"100","author":"T Taniguchi","year":"2002","unstructured":"Taniguchi T, Garcia-Higuera I, Andreassen PR, Gregory RC, Grompe M, D'Andrea AD . S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood 2002; 100: 2414\u20132420.","journal-title":"Blood"},{"key":"BFonc2013327_CR32","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.1038\/sj.emboj.7600113","volume":"23","author":"P Pichierri","year":"2004","unstructured":"Pichierri P, Rosselli F . The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways. EMBO J 2004; 23: 1178\u20131187.","journal-title":"EMBO J"},{"key":"BFonc2013327_CR33","doi-asserted-by":"publisher","first-page":"5140","DOI":"10.1182\/blood-2010-04-278226","volume":"116","author":"QS Zhang","year":"2010","unstructured":"Zhang QS, Marquez-Loza L, Eaton L, Duncan AW, Goldman DC, Anur P et al. Fancd2-\/- mice have hematopoietic defects that can be partially corrected by resveratrol. Blood 2010; 116: 5140\u20135148.","journal-title":"Blood"},{"key":"BFonc2013327_CR34","doi-asserted-by":"publisher","first-page":"7712","DOI":"10.1128\/JVI.75.16.7712-7716.2001","volume":"75","author":"S Duensing","year":"2001","unstructured":"Duensing S, Duensing A, Flores ER, Do A, Lambert PF, Munger K . Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes. J Virol 2001; 75: 7712\u20137716.","journal-title":"J Virol"},{"key":"BFonc2013327_CR35","doi-asserted-by":"publisher","first-page":"6241","DOI":"10.1038\/sj.onc.1205709","volume":"21","author":"S Duensing","year":"2002","unstructured":"Duensing S, Munger K . Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability. Oncogene 2002; 21: 6241\u20136248.","journal-title":"Oncogene"},{"key":"BFonc2013327_CR36","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1101\/gad.8.6.666","volume":"8","author":"AE White","year":"1994","unstructured":"White AE, Livanos EM, Tlsty TD . Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. Genes Dev 1994; 8: 666\u2013677.","journal-title":"Genes Dev"},{"key":"BFonc2013327_CR37","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1038\/nature03114","volume":"432","author":"Y Huyen","year":"2004","unstructured":"Huyen Y, Zgheib O, Ditullio RA Jr, Gorgoulis VG, Zacharatos P, Petty TJ et al. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 2004; 432: 406\u2013411.","journal-title":"Nature"},{"key":"BFonc2013327_CR38","doi-asserted-by":"publisher","first-page":"11492","DOI":"10.1073\/pnas.0505337102","volume":"102","author":"KW Huh","year":"2005","unstructured":"Huh KW, DeMasi J, Ogawa H, Nakatani Y, Howley PM, Munger K . Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600. Proc Natl Acad Sci USA 2005; 102: 11492\u201311497.","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFonc2013327_CR39","doi-asserted-by":"publisher","first-page":"9928","DOI":"10.1158\/0008-5472.CAN-08-2051","volume":"68","author":"SH Chung","year":"2008","unstructured":"Chung SH, Wiedmeyer K, Shai A, Korach KS, Lambert PF . Requirement for estrogen receptor alpha in a mouse model for human papillomavirus-associated cervical cancer. Cancer Res 2008; 68: 9928\u20139934.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR40","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1016\/S1534-5807(03)00339-3","volume":"5","author":"TX Liu","year":"2003","unstructured":"Liu TX, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J et al. Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis. Dev Cell 2003; 5: 903\u2013914.","journal-title":"Dev Cell"},{"key":"BFonc2013327_CR41","first-page":"85","volume":"65","author":"S Houghtaling","year":"2005","unstructured":"Houghtaling S, Granville L, Akkari Y, Torimaru Y, Olson S, Finegold M et al. Heterozygosity for p53 (Trp53+\/-) accelerates epithelial tumor formation in fanconi anemia complementation group D2 (Fancd2) knockout mice. Cancer Res 2005; 65: 85\u201391.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR42","doi-asserted-by":"publisher","first-page":"2622","DOI":"10.1158\/0008-5472.CAN-07-5266","volume":"68","author":"A Shai","year":"2008","unstructured":"Shai A, Pitot HC, Lambert PF . p53 Loss synergizes with estrogen and papillomaviral oncogenes to induce cervical and breast cancers. Cancer Res 2008; 68: 2622\u20132631.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR43","doi-asserted-by":"publisher","first-page":"1400","DOI":"10.1002\/jcb.21609","volume":"102","author":"A Sun","year":"2007","unstructured":"Sun A, Bagella L, Tutton S, Romano G, Giordano A . From G0 to S phase: a view of the roles played by the retinoblastoma (Rb) family members in the Rb-E2F pathway. J Cell Biochem 2007; 102: 1400\u20131404.","journal-title":"J Cell Biochem"},{"key":"BFonc2013327_CR44","first-page":"2561","volume":"8","author":"X Mayol","year":"1993","unstructured":"Mayol X, Grana X, Baldi A, Sang N, Hu Q, Giordano A . Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain. Oncogene 1993; 8: 2561\u20132566.","journal-title":"Oncogene"},{"key":"BFonc2013327_CR45","doi-asserted-by":"publisher","first-page":"2378","DOI":"10.1101\/gad.7.12a.2378","volume":"7","author":"GJ Hannon","year":"1993","unstructured":"Hannon GJ, Demetrick D, Beach D . Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes Dev 1993; 7: 2378\u20132391.","journal-title":"Genes Dev"},{"key":"BFonc2013327_CR46","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/0092-8674(89)90840-4","volume":"58","author":"ME Ewen","year":"1989","unstructured":"Ewen ME, Ludlow JW, Marsilio E, DeCaprio JA, Millikan RC, Cheng SH et al. An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120. Cell 1989; 58: 257\u2013267.","journal-title":"Cell"},{"key":"BFonc2013327_CR47","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/0092-8674(89)90839-8","volume":"58","author":"N Dyson","year":"1989","unstructured":"Dyson N, Buchkovich K, Whyte P, Harlow E . The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus. Cell 1989; 58: 249\u2013255.","journal-title":"Cell"},{"key":"BFonc2013327_CR48","doi-asserted-by":"publisher","first-page":"8733","DOI":"10.1158\/0008-5472.CAN-09-1359","volume":"69","author":"DS Simpson","year":"2009","unstructured":"Simpson DS, Mason-Richie NA, Gettler CA, Wikenheiser-Brokamp KA Retinoblastoma family proteins have distinct functions in pulmonary epithelial cells in vivo critical for suppressing cell growth and tumorigenesis. Cancer Res 2009; 69: 8733\u20138741.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR49","doi-asserted-by":"publisher","first-page":"3877","DOI":"10.1158\/0008-5472.CAN-09-4228","volume":"70","author":"BE Schaffer","year":"2010","unstructured":"Schaffer BE, Park KS, Yiu G, Conklin JF, Lin C, Burkhart DL et al. Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. Cancer Res 2010; 70: 3877\u20133883.","journal-title":"Cancer Res"},{"key":"BFonc2013327_CR50","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.1101\/gad.12.11.1599","volume":"12","author":"E Robanus-Maandag","year":"1998","unstructured":"Robanus-Maandag E, Dekker M, van der Valk M, Carrozza ML, Jeanny JC, Dannenberg JH et al. p107 is a suppressor of retinoblastoma development in pRb-deficient mice. Genes Dev 1998; 12: 1599\u20131609.","journal-title":"Genes Dev"},{"key":"BFonc2013327_CR51","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1038\/onc.2008.491","volume":"28","author":"VM Ho","year":"2009","unstructured":"Ho VM, Schaffer BE, Karnezis AN, Park KS, Sage J . The retinoblastoma gene Rb and its family member p130 suppress lung adenocarcinoma induced by oncogenic K-Ras. Oncogene 2009; 28: 1393\u20131399.","journal-title":"Oncogene"},{"key":"BFonc2013327_CR52","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/S0092-8674(02)00747-X","volume":"109","author":"T Taniguchi","year":"2002","unstructured":"Taniguchi T, Garcia-Higuera I, Xu B, Andreassen PR, Gregory RC, Kim ST et al. Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. Cell 2002; 109: 459\u2013472.","journal-title":"Cell"},{"key":"BFonc2013327_CR53","doi-asserted-by":"publisher","first-page":"e1000318","DOI":"10.1371\/journal.ppat.1000318","volume":"5","author":"D Pyeon","year":"2009","unstructured":"Pyeon D, Pearce SM, Lank SM, Ahlquist P, Lambert PF . Establishment of human papillomavirus infection requires cell cycle progression. PLoS Pathog 2009; 5: e1000318.","journal-title":"PLoS Pathog"},{"key":"BFonc2013327_CR54","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1111\/j.1601-0825.2011.01803.x","volume":"17","author":"MR de Araujo","year":"2011","unstructured":"de Araujo MR, Rubira-Bullen IR, Santos CF, Dionisio TJ, Bonfim CM, De Marco L et al. High prevalence of oral human papillomavirus infection in Fanconi's anemia patients. Oral Dis 2011; 17: 572\u2013576.","journal-title":"Oral Dis"},{"key":"BFonc2013327_CR55","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1128\/MMBR.68.2.362-372.2004","volume":"68","author":"MS Longworth","year":"2004","unstructured":"Longworth MS, Laimins LA . Pathogenesis of human papillomaviruses in differentiating epithelia. Microbiol Mol Biol Rev 2004; 68: 362\u2013372.","journal-title":"Microbiol Mol Biol Rev"},{"key":"BFonc2013327_CR56","doi-asserted-by":"publisher","first-page":"8131","DOI":"10.1128\/JVI.00408-12","volume":"86","author":"EE Hoskins","year":"2012","unstructured":"Hoskins EE, Morreale RJ, Werner SP, Higginbotham JM, Laimins LA, Lambert PF et al. The Fanconi anemia pathway limits human papillomavirus replication. J Virol 2012; 86: 8131\u20138138.","journal-title":"J Virol"},{"key":"BFonc2013327_CR57","doi-asserted-by":"crossref","first-page":"5887","DOI":"10.1128\/JVI.73.7.5887-5893.1999","volume":"73","author":"S Song","year":"1999","unstructured":"Song S, Pitot HC, Lambert PF . The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals. J Virol 1999; 73: 5887\u20135893.","journal-title":"J Virol"},{"key":"BFonc2013327_CR58","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1128\/jvi.70.3.1873-1881.1996","volume":"70","author":"R Herber","year":"1996","unstructured":"Herber R, Liem A, Pitot H, Lambert PF . Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene. J Virol 1996; 70: 1873\u20131881.","journal-title":"J Virol"},{"key":"BFonc2013327_CR59","doi-asserted-by":"publisher","first-page":"2021","DOI":"10.1101\/gad.1103403","volume":"17","author":"S Houghtaling","year":"2003","unstructured":"Houghtaling S, Timmers C, Noll M, Finegold MJ, Jones SN, Meyn MS et al. Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice. Genes Dev 2003; 17: 2021\u20132035.","journal-title":"Genes Dev"}],"container-title":["Oncogene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/onc2013327.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/onc2013327","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/onc2013327.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T19:41:35Z","timestamp":1647891695000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/onc2013327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,9]]},"references-count":59,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2014,6,26]]}},"alternative-id":["BFonc2013327"],"URL":"https:\/\/doi.org\/10.1038\/onc.2013.327","relation":{},"ISSN":["0950-9232","1476-5594"],"issn-type":[{"value":"0950-9232","type":"print"},{"value":"1476-5594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,9]]},"assertion":[{"value":"5 March 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 June 2013","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 June 2013","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 September 2013","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}