{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T23:00:33Z","timestamp":1789426833102,"version":"build-2803163510"},"reference-count":57,"publisher":"Springer Science and Business Media LLC","issue":"46","license":[{"start":{"date-parts":[[2013,11,18]],"date-time":"2013-11-18T00:00:00Z","timestamp":1384732800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2013,11,18]],"date-time":"2013-11-18T00:00:00Z","timestamp":1384732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oncogene"],"published-print":{"date-parts":[[2014,11,13]]},"DOI":"10.1038\/onc.2013.476","type":"journal-article","created":{"date-parts":[[2013,11,18]],"date-time":"2013-11-18T11:30:47Z","timestamp":1384774247000},"page":"5319-5331","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":66,"title":["Protumorigenic effects of mir-145 loss in malignant pleural mesothelioma"],"prefix":"10.1038","volume":"33","author":[{"given":"M","family":"Cioce","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Ganci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Canu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Sacconi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Canino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Korita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Casini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Alessandrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Cambria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M A","family":"Carosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Blandino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Panebianco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Facciolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Visca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Volinia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Muti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Strano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C M","family":"Croce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H I","family":"Pass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Blandino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,11,18]]},"reference":[{"key":"BFonc2013476_CR1","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1586\/14737140.8.2.293","volume":"8","author":"AJ Kaufman","year":"2008","unstructured":"Kaufman AJ, Pass HI . Current concepts in malignant pleural mesothelioma. Expert Review Anticancer Ther 2008; 8: 293\u2013303.","journal-title":"Expert Review Anticancer Ther"},{"key":"BFonc2013476_CR2","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1002\/jcp.22724","volume":"227","author":"M Carbone","year":"2012","unstructured":"Carbone M, Ly BH, Dodson RF, Pagano I, Morris PT, Dogan UA et al. Malignant mesothelioma: facts, myths, and hypotheses. J Cell Physio 2012; 227: 44\u201358.","journal-title":"J Cell Physio"},{"key":"BFonc2013476_CR3","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1158\/1078-0432.982.11.3","volume":"11","author":"M Hazarika","year":"2005","unstructured":"Hazarika M, White RM Jr., Booth BP, Wang YC, Ham DY, Liang CY et al. Pemetrexed in malignant pleural mesothelioma. Clin Cancer Res 2005; 11: 982\u2013992.","journal-title":"Clin Cancer Res"},{"key":"BFonc2013476_CR4","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.jtcvs.2009.11.072","volume":"140","author":"AA Mujoomdar","year":"2010","unstructured":"Mujoomdar AA, Tilleman TR, Richards WG, Bueno R, Sugarbaker DJ . Prevalence of in vitro chemotherapeutic drug resistance in primary malignant pleural mesothelioma: result in a cohort of 203 resection specimens. J Thorac Cardiov Sur 2010; 140: 352\u2013355.","journal-title":"J Thorac Cardiov Sur"},{"key":"BFonc2013476_CR5","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1016\/j.bbagrm.2008.06.006","volume":"1779","author":"G Tang","year":"2008","unstructured":"Tang G, Tang X, Mendu V, Tang X, Jia X, Chen QJ et al. The art of microRNA: various strategies leading to gene silencing via an ancient pathway. Biochimica et biophysica acta 2008; 1779: 655\u2013662.","journal-title":"Biochimica et biophysica acta"},{"key":"BFonc2013476_CR6","first-page":"99","volume":"320","author":"X Ji","year":"2008","unstructured":"Ji X . The mechanism of RNase III action: how dicer dices. Curr Top Microbiol 2008; 320: 99\u2013116.","journal-title":"Curr Top Microbiol"},{"key":"BFonc2013476_CR7","doi-asserted-by":"publisher","first-page":"2643","DOI":"10.4161\/cc.7.17.6597","volume":"7","author":"S Deng","year":"2008","unstructured":"Deng S, Calin GA, Croce CM, Coukos G, Zhang L . Mechanisms of microRNA deregulation in human cancer. Cell Cycle 2008; 7: 2643\u20132646.","journal-title":"Cell Cycle"},{"key":"BFonc2013476_CR8","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.leukres.2005.10.017","volume":"30","author":"GA Calin","year":"2006","unstructured":"Calin GA, Garzon R, Cimmino A, Fabbri M, Croce CM . MicroRNAs and leukemias: how strong is the connection? Leukemia Res 2006; 30: 653\u2013655.","journal-title":"Leukemia Res"},{"key":"BFonc2013476_CR9","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1038\/nrc1997","volume":"6","author":"GA Calin","year":"2006","unstructured":"Calin GA, Croce CM . MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857\u2013866.","journal-title":"Nat Rev Cancer"},{"key":"BFonc2013476_CR10","doi-asserted-by":"publisher","first-page":"1916","DOI":"10.1158\/0008-5472.CAN-09-3993","volume":"70","author":"HI Pass","year":"2010","unstructured":"Pass HI, Goparaju C, Ivanov S, Donington J, Carbone M, Hoshen M et al. hsa-miR-29c* is linked to the prognosis of malignant pleural mesothelioma. Cancer Res 2010; 70: 1916\u20131924.","journal-title":"Cancer Res"},{"key":"BFonc2013476_CR11","doi-asserted-by":"publisher","first-page":"2479","DOI":"10.1002\/ijc.27949","volume":"132","author":"G Pignot","year":"2013","unstructured":"Pignot G, Cizeron-Clairac G, Vacher S, Susini A, Tozlu S, Vieillefond A et al. microRNA expression profile in a large series of bladder tumors: identification of a 3-miRNA signature associated with aggressiveness of muscle-invasive bladder cancer. Int J Cancer 2013; 132: 2479\u20132491.","journal-title":"Int J Cancer"},{"key":"BFonc2013476_CR12","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1016\/j.fertnstert.2012.11.055","volume":"99","author":"M Adammek","year":"2013","unstructured":"Adammek M, Greve B, Kassens N, Schneider C, Bruggemann K, Schuring AN et al. MicroRNA miR-145 inhibits proliferation, invasiveness, and stem cell phenotype of an in vitro endometriosis model by targeting multiple cytoskeletal elements and pluripotency factors. Fertil Steril 2013; 99: 1346\u20131355.","journal-title":"Fertil Steril"},{"key":"BFonc2013476_CR13","doi-asserted-by":"publisher","first-page":"3989","DOI":"10.1002\/cncr.25944","volume":"117","author":"Y Wu","year":"2011","unstructured":"Wu Y, Liu S, Xin H, Jiang J, Younglai E, Sun S et al. Up-regulation of microRNA-145 promotes differentiation by repressing OCT4 in human endometrial adenocarcinoma cells. Cancer 2011; 117: 3989\u20133998.","journal-title":"Cancer"},{"key":"BFonc2013476_CR14","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1002\/ijc.24827","volume":"126","author":"A Schaefer","year":"2010","unstructured":"Schaefer A, Jung M, Mollenkopf HJ, Wagner I, Stephan C, Jentzmik F et al. Diagnostic and prognostic implications of microRNA profiling in prostate carcinoma. Int J Cancer 2010; 126: 1166\u20131176.","journal-title":"Int J Cancer"},{"key":"BFonc2013476_CR15","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1016\/j.cell.2009.02.038","volume":"137","author":"N Xu","year":"2009","unstructured":"Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS . MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 2009; 137: 647\u2013658.","journal-title":"Cell"},{"key":"BFonc2013476_CR16","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1089\/scd.2009.0113","volume":"18","author":"V Kashyap","year":"2009","unstructured":"Kashyap V, Rezende NC, Scotland KB, Shaffer SM, Persson JL, Gudas LJ et al. Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem cells and development 2009; 18: 1093\u20131108.","journal-title":"Stem cells and development"},{"key":"BFonc2013476_CR17","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/1757-2215-5-37","volume":"5","author":"C Samardzija","year":"2012","unstructured":"Samardzija C, Quinn M, Findlay JK, Ahmed N . Attributes of Oct4 in stem cell biology: perspectives on cancer stem cells of the ovary. Journal of ovarian research 2012; 5: 37.","journal-title":"Journal of ovarian research"},{"key":"BFonc2013476_CR18","doi-asserted-by":"publisher","first-page":"4898","DOI":"10.1038\/onc.2011.656","volume":"31","author":"SM Kumar","year":"2012","unstructured":"Kumar SM, Liu S, Lu H, Zhang H, Zhang PJ, Gimotty PA et al. Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation. Oncogene 2012; 31: 4898\u20134911.","journal-title":"Oncogene"},{"key":"BFonc2013476_CR19","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1111\/j.1600-0714.2011.01015.x","volume":"40","author":"LL Tsai","year":"2011","unstructured":"Tsai LL, Yu CC, Chang YC, Yu CH, Chou MY . Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma. J Oral Pathol Med 2011; 40: 621\u2013628.","journal-title":"J Oral Pathol Med"},{"key":"BFonc2013476_CR20","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1177\/1947601910388271","volume":"1","author":"DE Linn","year":"2010","unstructured":"Linn DE, Yang X, Sun F, Xie Y, Chen H, Jiang R et al. A Role for OCT4 in Tumor Initiation of Drug-Resistant Prostate Cancer Cells. Genes & cancer 2010; 1: 908\u2013916.","journal-title":"Genes & cancer"},{"key":"BFonc2013476_CR21","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1002\/glia.20800","volume":"57","author":"Z Du","year":"2009","unstructured":"Du Z, Jia D, Liu S, Wang F, Li G, Zhang Y et al. Oct4 is expressed in human gliomas and promotes colony formation in glioma cells. Glia 2009; 57: 724\u2013733.","journal-title":"Glia"},{"key":"BFonc2013476_CR22","doi-asserted-by":"publisher","first-page":"10433","DOI":"10.1158\/0008-5472.CAN-10-2638","volume":"70","author":"SH Chiou","year":"2010","unstructured":"Chiou SH, Wang ML, Chou YT, Chen CJ, Hong CF, Hsieh WJ et al. Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Res 2010; 70: 10433\u201310444.","journal-title":"Cancer Res"},{"key":"BFonc2013476_CR23","doi-asserted-by":"publisher","first-page":"155","DOI":"10.3892\/or.2012.2086","volume":"29","author":"X Dai","year":"2013","unstructured":"Dai X, Ge J, Wang X, Qian X, Zhang C, Li X . OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion. Oncol Rep 2013; 29: 155\u2013160.","journal-title":"Oncol Rep"},{"key":"BFonc2013476_CR24","doi-asserted-by":"publisher","first-page":"2153","DOI":"10.1038\/onc.2009.500","volume":"29","author":"S Peng","year":"2010","unstructured":"Peng S, Maihle NJ, Huang Y . Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer. Oncogene 2010; 29: 2153\u20132159.","journal-title":"Oncogene"},{"key":"BFonc2013476_CR25","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1093\/bmb\/ldp047","volume":"93","author":"RM Rudd","year":"2010","unstructured":"Rudd RM . Malignant mesothelioma. Brit Med Bull 2010; 93: 105\u2013123.","journal-title":"Brit Med Bull"},{"key":"BFonc2013476_CR26","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.canlet.2011.01.009","volume":"302","author":"C Casarsa","year":"2011","unstructured":"Casarsa C, Bassani N, Ambrogi F, Zabucchi G, Boracchi P, Biganzoli E et al. Epithelial-to-mesenchymal transition, cell polarity and stemness-associated features in malignant pleural mesothelioma. Cancer Lett 2011; 302: 136\u2013143.","journal-title":"Cancer Lett"},{"key":"BFonc2013476_CR27","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1016\/j.ejcts.2009.08.027","volume":"37","author":"A Schramm","year":"2010","unstructured":"Schramm A, Opitz I, Thies S, Seifert B, Moch H, Weder W et al. Prognostic significance of epithelial-mesenchymal transition in malignant pleural mesothelioma. European journal of cardio-thoracic surgery. official journal of the European Association for Cardio-thoracic Surgery 2010; 37: 566\u2013572.","journal-title":"official journal of the European Association for Cardio-thoracic Surgery"},{"key":"BFonc2013476_CR28","doi-asserted-by":"publisher","first-page":"2066","DOI":"10.1091\/mbc.e11-10-0884","volume":"23","author":"A Freund","year":"2012","unstructured":"Freund A, Laberge RM, Demaria M, Campisi J . Lamin B1 loss is a senescence-associated biomarker. Mol Biol Cell 2012; 23: 2066\u20132075.","journal-title":"Mol Biol Cell"},{"key":"BFonc2013476_CR29","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/j.cell.2006.05.052","volume":"126","author":"M Narita","year":"2006","unstructured":"Narita M, Narita M, Krizhanovsky V, Nunez S, Chicas A, Hearn SA et al. A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation. Cell 2006; 126: 503\u2013514.","journal-title":"Cell"},{"key":"BFonc2013476_CR30","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1016\/S0092-8674(03)00401-X","volume":"113","author":"M Narita","year":"2003","unstructured":"Narita M, Nunez S, Heard E, Narita M, Lin AW, Hearn SA et al. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 2003; 113: 703\u2013716.","journal-title":"Cell"},{"key":"BFonc2013476_CR31","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1134\/S000629791206003X","volume":"77","author":"VS Romanov","year":"2012","unstructured":"Romanov VS, Pospelov VA, Pospelova TV . Cyclin-dependent kinase inhibitor p21(Waf1): contemporary view on its role in senescence and oncogenesis. Biochemistry Biokhimiia 2012; 77: 575\u2013584.","journal-title":"Biochemistry Biokhimiia"},{"key":"BFonc2013476_CR32","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/978-1-62703-239-1_25","volume":"965","author":"N Wajapeyee","year":"2013","unstructured":"Wajapeyee N, Deibler SK, Green MR . Genome-wide RNAi screening to identify regulators of oncogene-induced cellular senescence. Methods Mol Biol 2013; 965: 373\u2013382.","journal-title":"Methods Mol Biol"},{"key":"BFonc2013476_CR33","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1177\/154411130201300603","volume":"13","author":"WC Weinberg","year":"2002","unstructured":"Weinberg WC, Denning MF . P21Waf1 control of epithelial cell cycle and cell fate. Crit Rev Oral Biol Med 2002; 13: 453\u2013464.","journal-title":"Crit Rev Oral Biol Med"},{"key":"BFonc2013476_CR34","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.lungcan.2010.04.020","volume":"70","author":"K Kai","year":"2010","unstructured":"Kai K, D'Costa S, Yoon BI, Brody AR, Sills RC, Kim Y . Characterization of side population cells in human malignant mesothelioma cell lines. Lung Cancer 2010; 70: 146\u2013151.","journal-title":"Lung Cancer"},{"key":"BFonc2013476_CR35","doi-asserted-by":"publisher","first-page":"3148","DOI":"10.1038\/onc.2011.485","volume":"31","author":"C Canino","year":"2012","unstructured":"Canino C, Mori F, Cambria A, Diamantini A, Germoni S, Alessandrini G et al. SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells. Oncogene 2012; 31: 3148\u20133163.","journal-title":"Oncogene"},{"key":"BFonc2013476_CR36","first-page":"15","volume":"28","author":"M Yilmaz","year":"2009","unstructured":"Yilmaz M, Christofori G . EMT, the cytoskeleton, and cancer cell invasion. Cancer\u00a0Metast Rev 2009; 28: 15\u201333.","journal-title":"Cancer\u00a0Metast Rev"},{"key":"BFonc2013476_CR37","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/j.stem.2010.08.012","volume":"7","author":"L Warren","year":"2010","unstructured":"Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell stem cell 2010; 7: 618\u2013630.","journal-title":"Cell stem cell"},{"key":"BFonc2013476_CR38","doi-asserted-by":"publisher","first-page":"R94","DOI":"10.1186\/bcr3019","volume":"13","author":"AS Beltran","year":"2011","unstructured":"Beltran AS, Rivenbark AG, Richardson BT, Yuan X, Quian H, Hunt JP et al. Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor. Breast Cancer Res 2011; 13: R94.","journal-title":"Breast Cancer Res"},{"key":"BFonc2013476_CR39","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.5858\/2005-129-1428-RAUOUP","volume":"129","author":"L Granville","year":"2005","unstructured":"Granville L, Laga AC, Allen TC, Dishop M, Roggli VL, Churg A et al. Review and update of uncommon primary pleural tumors: a practical approach to diagnosis. Arch Pathol Lab Med 2005; 129: 1428\u20131443.","journal-title":"Arch Pathol Lab Med"},{"key":"BFonc2013476_CR40","doi-asserted-by":"publisher","first-page":"277","DOI":"10.5858\/arpa.2011-0215-RA","volume":"136","author":"D Jean","year":"2012","unstructured":"Jean D, Daubriac J, Le Pimpec-Barthes F, Galateau-Salle F, Jaurand MC . Molecular changes in mesothelioma with an impact on prognosis and treatment. Arch Pathol Lab Med 2012; 136: 277\u2013293.","journal-title":"Arch Pathol Lab Med"},{"key":"BFonc2013476_CR41","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1038\/onc.2012.28","volume":"32","author":"J Zhang","year":"2013","unstructured":"Zhang J, Sun Q, Zhang Z, Ge S, Han ZG, Chen WT . Loss of microRNA-143\/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. Oncogene 2013; 32: 61\u201369.","journal-title":"Oncogene"},{"key":"BFonc2013476_CR42","doi-asserted-by":"publisher","first-page":"67","DOI":"10.3892\/or.2012.2084","volume":"29","author":"Y Lu","year":"2013","unstructured":"Lu Y, Chopp M, Zheng X, Katakowski M, Buller B, Jiang F . MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells. Oncology reports 2013; 29: 67\u201372.","journal-title":"Oncology reports"},{"key":"BFonc2013476_CR43","doi-asserted-by":"publisher","first-page":"e54652","DOI":"10.1371\/journal.pone.0054652","volume":"8","author":"HK Lee","year":"2013","unstructured":"Lee HK, Bier A, Cazacu S, Finniss S, Xiang C, Twito H et al. MicroRNA-145 Is Downregulated in Glial Tumors and Regulates Glioma Cell Migration by Targeting Connective Tissue Growth Factor. PloS One 2013; 8: e54652.","journal-title":"PloS One"},{"key":"BFonc2013476_CR44","doi-asserted-by":"publisher","first-page":"723","DOI":"10.18632\/oncotarget.547","volume":"3","author":"MC Speranza","year":"2012","unstructured":"Speranza MC, Frattini V, Pisati F, Kapetis D, Porrati P, Eoli M et al. NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma. Oncotarget 2012; 3: 723\u2013734.","journal-title":"Oncotarget"},{"key":"BFonc2013476_CR45","doi-asserted-by":"publisher","first-page":"2062","DOI":"10.1158\/1535-7163.MCT-11-0381","volume":"10","author":"CM Klinge","year":"2011","unstructured":"Klinge CM, Radde BN, Imbert-Fernandez Y, Teng Y, Ivanova MM, Abner SM et al. Targeting the intracellular MUC1 C-terminal domain inhibits proliferation and estrogen receptor transcriptional activity in lung adenocarcinoma cells. Mol Cancer Ther 2011; 10: 2062\u20132071.","journal-title":"Mol Cancer Ther"},{"key":"BFonc2013476_CR46","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1186\/1476-4598-9-211","volume":"9","author":"J Zhang","year":"2010","unstructured":"Zhang J, Guo H, Qian G, Ge S, Ji H, Hu X et al. MiR-145, a new regulator of the DNA fragmentation factor-45 (DFF45)-mediated apoptotic network. Mol Cancer 2010; 9: 211.","journal-title":"Mol Cancer"},{"key":"BFonc2013476_CR47","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1186\/1756-9966-29-151","volume":"29","author":"Z Chen","year":"2010","unstructured":"Chen Z, Zeng H, Guo Y, Liu P, Pan H, Deng A et al. miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc. J Exp Clin Canc Res 2010; 29: 151.","journal-title":"J Exp Clin Canc Res"},{"key":"BFonc2013476_CR48","first-page":"1461","volume":"34","author":"S Wang","year":"2009","unstructured":"Wang S, Bian C, Yang Z, Bo Y, Li J, Zeng L et al. miR-145 inhibits breast cancer cell growth through RTKN. Int J Oncol 2009; 34: 1461\u20131466.","journal-title":"Int J Oncol"},{"key":"BFonc2013476_CR49","doi-asserted-by":"publisher","first-page":"pii:e12519","DOI":"10.1371\/journal.pone.0012519","volume":"5","author":"LN Bonifacio","year":"2010","unstructured":"Bonifacio LN, Jarstfer MB . MiRNA profile associated with replicative senescence, extended cell culture, and ectopic telomerase expression in human foreskin fibroblasts. PLoS One 2010; 5: pii:e12519.","journal-title":"PLoS One"},{"key":"BFonc2013476_CR50","doi-asserted-by":"publisher","first-page":"e52188","DOI":"10.1371\/journal.pone.0052188","volume":"7","author":"D Basu","year":"2012","unstructured":"Basu D, Reyes-Mugica M, Rebbaa A . Role of the beta catenin destruction complex in mediating chemotherapy-induced senescence-associated secretory phenotype. PLoS One 2012; 7: e52188.","journal-title":"PLoS One"},{"key":"BFonc2013476_CR51","doi-asserted-by":"crossref","unstructured":"Cahu J, Bustany S, Sola B . Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells. Cell death & disease 2012; 3: e446.","DOI":"10.1038\/cddis.2012.183"},{"key":"BFonc2013476_CR52","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/978-1-62703-239-1_10","volume":"965","author":"F Rodier","year":"2013","unstructured":"Rodier F . Detection of the senescence-associated secretory phenotype (SASP). Methods Mol Biol 2013; 965: 165\u2013173.","journal-title":"Methods Mol Biol"},{"issue":"Suppl 3","key":"BFonc2013476_CR53","doi-asserted-by":"publisher","first-page":"S656","DOI":"10.1245\/s10434-012-2217-6","volume":"19","author":"J Kurashige","year":"2012","unstructured":"Kurashige J, Kamohara H, Watanabe M, Hiyoshi Y, Iwatsuki M, Tanaka Y et al. MicroRNA-200b regulates cell proliferation, invasion, and migration by directly targeting ZEB2 in gastric carcinoma. Ann Oncol 2012; 19 (Suppl 3): S656\u2013S664.","journal-title":"Ann Oncol"},{"key":"BFonc2013476_CR54","doi-asserted-by":"publisher","first-page":"1686","DOI":"10.1091\/mbc.e11-02-0103","volume":"22","author":"PA Gregory","year":"2011","unstructured":"Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S et al. An autocrine TGF-beta\/ZEB\/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Cell Biol 2011; 22: 1686\u20131698.","journal-title":"Mol Cell Biol"},{"key":"BFonc2013476_CR55","doi-asserted-by":"publisher","first-page":"3112","DOI":"10.4161\/cc.7.20.6851","volume":"7","author":"PA Gregory","year":"2008","unstructured":"Gregory PA, Bracken CP, Bert AG, Goodall GJ . MicroRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle 2008; 7: 3112\u20133118.","journal-title":"Cell Cycle"},{"key":"BFonc2013476_CR56","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1038\/onc.2013.55","volume":"33","author":"P Ceppi","year":"2014","unstructured":"Ceppi P, Peter ME . MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells. Oncogene 2014; 33: 269\u2013278.","journal-title":"Oncogene"},{"key":"BFonc2013476_CR57","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1038\/onc.2013.13","volume":"33","author":"H Nakanishi","year":"2014","unstructured":"Nakanishi H, Taccioli C, Palatini J, Fernandez-Cymering C, Cui R, Kim T et al. Loss of miR-125b-1 contributes to head and neck cancer development by dysregulating TACSTD2 and MAPK pathway. Oncogene 2014; 33: 702\u2013712.","journal-title":"Oncogene"}],"container-title":["Oncogene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/onc2013476.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/onc2013476","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/onc2013476.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,19]],"date-time":"2024-05-19T16:20:20Z","timestamp":1716135620000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/onc2013476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,18]]},"references-count":57,"journal-issue":{"issue":"46","published-print":{"date-parts":[[2014,11,13]]}},"alternative-id":["BFonc2013476"],"URL":"https:\/\/doi.org\/10.1038\/onc.2013.476","relation":{},"ISSN":["0950-9232","1476-5594"],"issn-type":[{"value":"0950-9232","type":"print"},{"value":"1476-5594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,18]]},"assertion":[{"value":"21 March 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 September 2013","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2013","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2013","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}