{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T05:04:28Z","timestamp":1693544668604},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,9,11]],"date-time":"2012-09-11T00:00:00Z","timestamp":1347321600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2012,9,11]],"date-time":"2012-09-11T00:00:00Z","timestamp":1347321600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Prostate Cancer Prostatic Dis"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1038\/pcan.2012.34","type":"journal-article","created":{"date-parts":[[2012,9,11]],"date-time":"2012-09-11T10:23:59Z","timestamp":1347359039000},"page":"73-78","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Detection of prostate cancer by radio-frequency near-field spectroscopy in radical prostatectomy ex vivo specimens"],"prefix":"10.1038","volume":"16","author":[{"given":"Z A","family":"Dotan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Fridman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Lindner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Ramon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Pode","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Bejar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Kopolovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Pizov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Sandbank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Shapiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Shilo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O","family":"Nativ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,9,11]]},"reference":[{"key":"BFpcan201234_CR1","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.urology.2005.06.116","volume":"66","author":"FJ Bianco","year":"2005","unstructured":"Bianco FJ, Scardino PT, Eastham JA . Radical prostatectomy: long-term cancer control and recovery of sexual and urinary function (\u2018trifecta\u2019). Urology 2005; 66: 83\u201394.","journal-title":"Urology"},{"key":"BFpcan201234_CR2","doi-asserted-by":"publisher","first-page":"1850","DOI":"10.1016\/S0022-5347(17)32399-6","volume":"152","author":"H Zincke","year":"1994","unstructured":"Zincke H, Oesterling JE, Blute ML, Bergstralh EJ, Myers RP, Barrett DM . Long-term (15 years) results after radical prostatectomy for clinically localized (stage T2c or lower) prostate cancer. J Urol 1994; 152: 1850\u20131857.","journal-title":"J Urol"},{"key":"BFpcan201234_CR3","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/S0022-5347(05)63946-8","volume":"169","author":"M Han","year":"2003","unstructured":"Han M, Partin AW, Zahurak M, Piantadosi S, Epstein JI, Walsh PC . Biochemical (prostate specific antigen) recurrence probability following radical prostatectomy for clinically localized prostate cancer. J Urol 2003; 169: 517\u2013523.","journal-title":"J Urol"},{"key":"BFpcan201234_CR4","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1097\/01.ju.0000098604.09395.27","volume":"171","author":"M Han","year":"2004","unstructured":"Han M, Partin AW, Chan DY, Walsh PC . An evaluation of the decreasing incidence of positive surgical margins in a large retropubic prostatectomy series. J Urol 2004; 171: 23\u201326.","journal-title":"J Urol"},{"key":"BFpcan201234_CR5","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1016\/j.urology.2005.06.108","volume":"66","author":"PI Karakiewicz","year":"2005","unstructured":"Karakiewicz PI, Eastham JA, Graefen M, Cagiannos I, Stricker PD, Klein E et al. Prognostic impact of positive surgical margins in surgically treated prostate cancer: multi-institutional assessment of 5831 patients. Urology 2005; 66: 1245\u20131250.","journal-title":"Urology"},{"key":"BFpcan201234_CR6","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1016\/j.urology.2007.08.040","volume":"70","author":"JA Eastham","year":"2007","unstructured":"Eastham JA, Kuroiwa K, Ohori M, Serio AM, Gorbonos A, Maru N et al. Prognostic significance of location of positive margins in radical prostatectomy specimens. Urology 2007; 70: 965\u2013969.","journal-title":"Urology"},{"key":"BFpcan201234_CR7","doi-asserted-by":"publisher","first-page":"1951","DOI":"10.1002\/cncr.23027","volume":"110","author":"KK Badani","year":"2007","unstructured":"Badani KK, Kaul S, Menon M . Evolution of robotic radical prostatectomy: assessment after 2766 procedures. Cancer 2007; 110: 1951\u20131958.","journal-title":"Cancer"},{"key":"BFpcan201234_CR8","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1093\/jnci\/90.10.766","volume":"90","author":"MW Kattan","year":"1998","unstructured":"Kattan MW, Eastham JA, Stapleton AM, Wheeler TM, Scardino PT . A preoperative nomogram for disease recurrence following radical prostatectomy for prostate cancer. J Natl Cancer Inst 1998; 90: 766\u2013771.","journal-title":"J Natl Cancer Inst"},{"key":"BFpcan201234_CR9","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.urolonc.2009.01.005","volume":"29","author":"ML Eisenberg","year":"2011","unstructured":"Eisenberg ML, Cowan JE, Davies BJ, Carroll PR, Shinohara K . The importance of tumor palpability and transrectal ultrasonographic appearance in the contemporary clinical staging of prostate cancer. Urol Oncol 2011; 29: 171\u2013176.","journal-title":"Urol Oncol"},{"key":"BFpcan201234_CR10","doi-asserted-by":"publisher","first-page":"2813","DOI":"10.1111\/j.1743-6109.2009.01437.x","volume":"6","author":"R Tal","year":"2009","unstructured":"Tal R, Valenzuela R, Aviv N, Parker M, Waters B, Flanigan RC et al. Persistent erectile dysfunction following radical prostatectomy: the association between nerve-sparing status and the prevalence and chronology of venous leak. J Sex Med 2009; 6: 2813\u20132819.","journal-title":"J Sex Med"},{"key":"BFpcan201234_CR11","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1016\/j.juro.2008.11.105","volume":"181","author":"T Marien","year":"2009","unstructured":"Marien T, Sankin A, Lepor H . Factors predicting preservation of erectile function in men undergoing open radical retropubic prostatectomy. J Urol 2009; 181: 1817\u20131822.","journal-title":"J Urol"},{"key":"BFpcan201234_CR12","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1097\/01.ju.0000138681.64035.dc","volume":"172","author":"JF Ward","year":"2004","unstructured":"Ward JF, Zincke H, Bergstralh EJ, Slezak JM, Myers RP, Blute ML . The impact of surgical approach (nerve bundle preservation versus wide local excision) on surgical margins and biochemical recurrence following radical prostatectomy. J Urol 2004; 172: 1328\u20131332.","journal-title":"J Urol"},{"key":"BFpcan201234_CR13","doi-asserted-by":"publisher","first-page":"1929","DOI":"10.1016\/S0022-5347(05)66921-2","volume":"164","author":"F Rabbani","year":"2000","unstructured":"Rabbani F, Stapleton AM, Kattan MW, Wheeler TM, Scardino PT . Factors predicting recovery of erections after radical prostatectomy. J Urol 2000; 164: 1929\u20131934.","journal-title":"J Urol"},{"key":"BFpcan201234_CR14","doi-asserted-by":"publisher","first-page":"e31","DOI":"10.1016\/j.eururo.2012.04.057","volume":"62","author":"T Schlomm","year":"2012","unstructured":"Schlomm T, Tennstedt P, Huxhold C, Steuber T, Salomon G, Michl U et al. Neurovascular structure-adjacent frozen-section examination (NeuroSAFE) increases nerve-sparing frequency and reduces positive surgical margins in open and robot-assisted laparoscopic radical prostatectomy: experience after 11\u2009069 consecutive patients. Eur Urol 2012; 62: e31\u2013e48.","journal-title":"Eur Urol"},{"key":"BFpcan201234_CR15","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1016\/j.eururo.2006.02.035","volume":"49","author":"C Eichelberg","year":"2006","unstructured":"Eichelberg C, Erbersdobler A, Haese A, Schlomm T, Chun FHK, Currlin E et al. Frozen section for the management of intraoperatively detected palpable tumor lesions during nerve-sparing scheduled radical prostatectomy. Eur Urol 2006; 49: 1011\u20131018.","journal-title":"Eur Urol"},{"key":"BFpcan201234_CR16","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1016\/j.urology.2005.06.073","volume":"66","author":"T Tsuboi","year":"2005","unstructured":"Tsuboi T, Ohori M, Kuroiwa K, Reuter VE, Kattan MW, Eastham JA et al. Is intraoperative frozen section analysis an efficient way to reduce positive surgical margins? Urology 2005; 66: 1287\u20131291.","journal-title":"Urology"},{"key":"BFpcan201234_CR17","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1016\/j.eururo.2005.06.015","volume":"48","author":"W Dillenburg","year":"2005","unstructured":"Dillenburg W, Poulakis V, Witzsch U, de Vries R, Skriapas K, Altmansberger HM et al. Laparoscopic radical prostatectomy: the value of intraoperative frozen sections. Eur Urol 2005; 48: 614\u2013621.","journal-title":"Eur Urol"},{"key":"BFpcan201234_CR18","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/S0090-4295(02)01539-X","volume":"59","author":"RZ Goharderakhshan","year":"2002","unstructured":"Goharderakhshan RZ, Sudilovsky D, Carroll LA, Grossfeld GD, Marn R, Carroll PR . Utility of intraoperative frozen section analysis of surgical margins in region of neurovascular bundles at radical prostatectomy. Urology 2002; 59: 709\u2013714.","journal-title":"Urology"},{"key":"BFpcan201234_CR19","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/j.urology.2003.10.017","volume":"63","author":"H Lepor","year":"2004","unstructured":"Lepor H, Kaci L . Role of intraoperative biopsies during radical retropubic prostatectomy. Urology 2004; 63: 499\u2013502.","journal-title":"Urology"},{"key":"BFpcan201234_CR20","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1080\/16070658.1981.11689230","volume":"16","author":"KR Foster","year":"1981","unstructured":"Foster KR, Schepps JL . Dielectric properties of tumor and normal tissues at radio through microwave frequencies. J Micro Power 1981; 16: 107\u2013119.","journal-title":"J Micro Power"},{"key":"BFpcan201234_CR21","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1118\/1.597312","volume":"21","author":"WT Joines","year":"1994","unstructured":"Joines WT, Zhang Y, Li C, Jirtle RL . The measured electrical properties of normal and malignant human tissues from 50 to 900\u2009MHz. Med Phys 1994; 21: 547\u2013550.","journal-title":"Med Phys"},{"key":"BFpcan201234_CR22","unstructured":"Sha L, Ward ER, Stroy B . A review of dielectric properties of normal and malignant breast tissue. IEEE SoutheastCon 2002, 457\u2013462."},{"key":"BFpcan201234_CR23","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.jss.2009.02.025","volume":"160","author":"I Pappo","year":"2010","unstructured":"Pappo I, Spector R, Schindel A, Morgenstern S, Sandbank J, Leider LT et al. Diagnostic performance of a novel device for real-time margin assessment in lumpectomy specimens. J Surg Res 2010; 160: 277\u2013281.","journal-title":"J Surg Res"},{"key":"BFpcan201234_CR24","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/j.amjsurg.2007.06.013","volume":"194","author":"T Karni","year":"2007","unstructured":"Karni T, Pappo I, Sandbank J, Lavon O, Kent V, Spector R et al. A device for real-time, intraoperative margin assessment in breast-conservation surgery. Am J Surg 2007; 194: 467\u2013473.","journal-title":"Am J Surg"},{"key":"BFpcan201234_CR25","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/j.amjsurg.2008.06.024","volume":"196","author":"TM Allweis","year":"2008","unstructured":"Allweis TM, Kaufman Z, Lelcuk S, Pappo I, Karni T, Schneebaum S et al. A prospective, randomized, controlled, multicenter study of a real-time, intraoperative probe for positive margin detection in breast-conserving surgery. Am J Surg 2008; 196: 483.","journal-title":"Am J Surg"},{"key":"BFpcan201234_CR26","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1007\/978-3-540-73841-1_35","volume":"17","author":"RJ Halter","year":"2007","unstructured":"Halter RJ, Schned A, Heaney J, Hartov A, Paulsen KD . Electrical impedance spectroscopy of prostatic tissues. IFMBE Proc 2007; 17: 126\u2013129.","journal-title":"IFMBE Proc"},{"key":"BFpcan201234_CR27","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.eururo.2008.02.022","volume":"55","author":"G Salomon","year":"2009","unstructured":"Salomon G, Hess T, Erbersdobler A, Eichelberg C, Greschner S, Sobchuk AN et al. The feasibility of prostate cancer detection by triple spectroscopy. Eur Urol 2009; 55: 376\u2013384.","journal-title":"Eur Urol"},{"key":"BFpcan201234_CR28","first-page":"259","volume":"25","author":"MT Sung","year":"2010","unstructured":"Sung MT, Cheng L . Contemporary approaches for processing and handling of radical prostatectomy specimens. Histol Histopathol 2010; 25: 259\u2013265.","journal-title":"Histol Histopathol"},{"key":"BFpcan201234_CR29","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1136\/jcp.2007.046789","volume":"61","author":"VS Bennett","year":"2008","unstructured":"Bennett VS, Varma M, Bailey DM . Guidelines for the macroscopic processing of radical prostatectomy and pelvic lymphadenectomy specimens. J Clin Pathol 2008; 61: 713\u2013721.","journal-title":"J Clin Pathol"},{"key":"BFpcan201234_CR30","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1007\/BF02344684","volume":"38","author":"JE Estrela da Silva","year":"2000","unstructured":"Estrela da Silva JE, Marques de Sa JP, Jossinet J . Classification of breast tissue by electrical impedance spectroscopy. Med Biol Eng Comput 2000; 38: 26\u201330.","journal-title":"Med Biol Eng Comput"}],"container-title":["Prostate Cancer and Prostatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/pcan201234.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/pcan201234","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/pcan201234.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T21:33:08Z","timestamp":1648675988000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/pcan201234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,11]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["BFpcan201234"],"URL":"https:\/\/doi.org\/10.1038\/pcan.2012.34","relation":{},"ISSN":["1365-7852","1476-5608"],"issn-type":[{"value":"1365-7852","type":"print"},{"value":"1476-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,11]]},"assertion":[{"value":"21 May 2012","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 July 2012","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 July 2012","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 September 2012","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}