{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T09:45:12Z","timestamp":1772012712436,"version":"3.50.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2016,8,9]],"date-time":"2016-08-09T00:00:00Z","timestamp":1470700800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2016,8,9]],"date-time":"2016-08-09T00:00:00Z","timestamp":1470700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Prostate Cancer Prostatic Dis"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1038\/pcan.2016.33","type":"journal-article","created":{"date-parts":[[2016,8,9]],"date-time":"2016-08-09T10:22:45Z","timestamp":1470738165000},"page":"406-411","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Morbidity and mortality after surgery for lower urinary tract symptoms: a study of 95\u2009577 cases from a nationwide German health insurance database"],"prefix":"10.1038","volume":"19","author":[{"given":"C","family":"Gilfrich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Leicht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Fahlenbrach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Jeschke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Popken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J U","family":"Stolzenburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Wei\u00dfbach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Zastrow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"G\u00fcnster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,8,9]]},"reference":[{"key":"BFpcan201633_CR1","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.eururo.2013.03.004","volume":"64","author":"M Oelke","year":"2015","unstructured":"Oelke M, Bachmann A, Descazeaud A, Emberton M, Gravas S, Michel MC et al. EAU guidelines on the treatment and follow-up of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction. Eur Urol 2015; 64: 118\u2013140.","journal-title":"Eur Urol"},{"key":"BFpcan201633_CR2","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/j.eururo.2010.06.005","volume":"58","author":"SA Ahyai","year":"2010","unstructured":"Ahyai SA, Gilling P, Kaplan SA, Kuntz RM, Madersbacher S, Montorsi F et al. Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement. Eur Urol 2010; 58: 384\u2013397.","journal-title":"Eur Urol"},{"key":"BFpcan201633_CR3","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1016\/j.eururo.2005.12.072","volume":"49","author":"O Reich","year":"2006","unstructured":"Reich O, Gratzke C, Stief CG . Techniques and long-term results of surgical procedures for BPH. Eur Urol 2006; 49: 970\u2013978.","journal-title":"Eur Urol"},{"key":"BFpcan201633_CR4","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/j.juro.2008.03.058","volume":"180","author":"O Reich","year":"2008","unstructured":"Reich O, Gratzke C, Bachmann A, Seitz M, Schlenker B, Hermanek P et al. Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. J Urol 2008; 180: 246\u2013249.","journal-title":"J Urol"},{"key":"BFpcan201633_CR5","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1016\/j.juro.2009.04.008","volume":"182","author":"C Jeldres","year":"2009","unstructured":"Jeldres C, Isbarn H, Capitanio U, Zini L, Bhojani N, Shariat SF et al. Development and external validation of a highly accurate nomogram for the prediction of perioperative mortality after transurethral resection of the prostate for benign prostatic hyperplasia. J Urol 2009; 182: 626\u2013632.","journal-title":"J Urol"},{"key":"BFpcan201633_CR6","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1016\/j.eururo.2014.06.017","volume":"67","author":"JN Cornu","year":"2015","unstructured":"Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C et al. A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: an update. Eur Urol 2015; 67: 1066\u20131096.","journal-title":"Eur Urol"},{"key":"BFpcan201633_CR7","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.eururo.2010.05.026","volume":"58","author":"A Al-Ansari","year":"2010","unstructured":"Al-Ansari A, Younes N, Sampige VP, Al-Rumaihi K, Ghafouri A, Gul T et al. GreenLight HPS 120-W laser vaporization versus transurethral resection of the prostate for treatment of benign prostatic hyperplasia: a randomized clinical trial with midterm follow-up. Eur Urol 2010; 58: 349\u2013355.","journal-title":"Eur Urol"},{"key":"BFpcan201633_CR8","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1111\/j.1464-410X.2006.05862.x","volume":"97","author":"N Gupta","year":"2006","unstructured":"Gupta N, Sivaramakrishna, Kumar R, Dogra PN, Seth A . Comparison of standard transurethral resection, transurethral vapour resection and holmium laser enucleation of the prostate for managing benign prostatic hyperplasia of >40\u2009g. BJU Int 2006; 97: 85\u201389.","journal-title":"BJU Int"},{"key":"BFpcan201633_CR9","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/j.eururo.2012.04.051","volume":"62","author":"IA Thangasamy","year":"2012","unstructured":"Thangasamy IA, Chalasani V, Bachmann A, Woo HH . Photoselective vaporisation of the prostate using 80-W and 120-W laser versus transurethral resection of the prostate for benign prostatic hyperplasia: a systematic review with meta-analysis from 2002 to 2012. Eur Urol 2012; 62: 315\u2013323.","journal-title":"Eur Urol"},{"key":"BFpcan201633_CR10","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1177\/1756287213511509","volume":"6","author":"M Cynk","year":"2014","unstructured":"Cynk M . Holmium laser enucleation of the prostate: a review of the clinical trial evidence. Ther Adv Urol 2014; 6: 62\u201373.","journal-title":"Ther Adv Urol"},{"key":"BFpcan201633_CR11","unstructured":"Federal Ministry of Health. Statutory Health Insurance Statistics KM1\/13: Annual average 2012. 2013; https:\/\/www.bundesgesundheitsministerium.de\/fileadmin\/dateien\/Downloads\/Statistiken\/GKV\/Mitglieder_Versicherte\/KM1_JD_2012.pdf (accessed on 31 July 2015)."},{"key":"BFpcan201633_CR12","unstructured":"Federal Statistical Office. Statistical Yearbook 2014. 2014; https:\/\/www.destatis.de\/DE\/Publikationen\/StatistischesJahrbuch\/StatistischesJahrbuch.html (accessed on 31 July 2015)."},{"key":"BFpcan201633_CR13","unstructured":"WIdO. Entwicklung des Leistungsbereichs \u2018\u2018Prostataoperation bei Benigner Prostataobstruktion\u2019\u2019: Abschlussbericht, 2014; http:\/\/qualitaetssicherung-mit-routinedaten.de\/methoden\/bereiche\/index.html (accessed on 11 August 2015)."},{"key":"BFpcan201633_CR14","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1097\/00005650-199801000-00004","volume":"36","author":"A Elixhauser","year":"1998","unstructured":"Elixhauser A, Steiner C, Harris DR, Coffey RM . Comorbidity measures for use with administrative data. Med Care 1998; 36: 8\u201327.","journal-title":"Med Care"},{"key":"BFpcan201633_CR15","unstructured":"Statistisches Bundesamt (2015). Daten der Jahr 2008\u20132013 nach 21 KHEntgG des Statistischen Bundesamtes. Statistisches Bundesamt, Wiesbaden, Germany."},{"key":"BFpcan201633_CR16","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1016\/j.juro.2011.11.102","volume":"187","author":"SA Strope","year":"2012","unstructured":"Strope SA, Yang L, Nepple KG, Andriole GL, Owens PL . Population-based comparative effectiveness of transurethral resection of the prostate and laser therapies for benign prostatic hyperplasia. J Urol 2012; 187: 1341\u20131345.","journal-title":"J Urol"},{"key":"BFpcan201633_CR17","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1089\/end.2014.0692","volume":"29","author":"BI Chughtai","year":"2015","unstructured":"Chughtai BI, Simma-Chiang V, Lee R, Isaacs A, Te AE, Kaplan SA et al. Trends and utilization of laser prostatectomy in ambulatory surgical procedures for the treatment of benign prostatic hyperplasia in New York State (2000-2011). J Endourol 2015; 29: 700\u2013706.","journal-title":"J Endourol"},{"key":"BFpcan201633_CR18","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1089\/end.2013.0805","volume":"28","author":"N Bhojani","year":"2014","unstructured":"Bhojani N, Gandaglia G, Sood A, Rai A, Pucheril D, Chang SL et al. Morbidity and mortality after benign prostatic hyperplasia surgery: data from the American College of Surgeons national surgical quality improvement program. J Endourol 2014; 28: 831\u2013840.","journal-title":"J Endourol"},{"key":"BFpcan201633_CR19","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/j.eururo.2004.12.010","volume":"47","author":"S Madersbacher","year":"2005","unstructured":"Madersbacher S, Lackner J, Br\u00f6ssner C, R\u00f6hlich M, Stancik I, Willinger M et al. Reoperation, myocardial infarction and mortality after transurethral and open prostatectomy: a nation-wide, long-term analysis of 23,123 cases. Eur Urol 2005; 47: 499\u2013504.","journal-title":"Eur Urol"},{"key":"BFpcan201633_CR20","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1111\/j.1464-410X.2012.11395.x","volume":"111","author":"J Teng","year":"2012","unstructured":"Teng J, Zhang D, Li Y, Yin L, Wang K, Cui X et al. Photoselective vaporization with the green light laser vs transurethral resection of the prostate for treating benign prostate hyperplasia: a systematic review and meta-analysis. BJU Int 2012; 111: 312\u2013323.","journal-title":"BJU Int"},{"key":"BFpcan201633_CR21","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1016\/j.eururo.2009.03.070","volume":"55","author":"R Naspro","year":"2009","unstructured":"Naspro R, Bachmann A, Gilling P, Kuntz R, Madersbacher S, Montorsi F et al. A review of the recent evidence (2006\u20132008) for 532-nm photoselective laser vaporisation and holmium laser enucleation of the prostate. Eur Urol 2009; 55: 1345\u20131357.","journal-title":"Eur Urol"},{"key":"BFpcan201633_CR22","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1016\/j.eururo.2007.04.053","volume":"52","author":"SA Ahyai","year":"2007","unstructured":"Ahyai SA, Lehrich K, Kuntz RM . Holmium laser enucleation versus transurethral resection of the prostate: 3-year follow-up results of a randomized clinical trial. Eur Urol 2007; 52: 1456\u20131463.","journal-title":"Eur Urol"},{"key":"BFpcan201633_CR23","doi-asserted-by":"publisher","first-page":"1926","DOI":"10.1097\/01.ju.0000140501.68841.a1","volume":"172","author":"F Montorsi","year":"2004","unstructured":"Montorsi F, Naspro R, Salonia A, Suardi N, Briganti A, Zanoni M et al. Holmium laser enucleation versus transurethral resection of the prostate: results from a 2-center, prospective, randomized trial in patients with obstructive benign prostatic hyperplasia. J Urol 2004; 172: 1926\u20131929.","journal-title":"J Urol"},{"key":"BFpcan201633_CR24","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1111\/j.1464-410X.2012.11119.x","volume":"110","author":"EK Mayer","year":"2012","unstructured":"Mayer EK, Kroeze SG, Chopra S, Bottle A, Patel A . Examining the 'gold standard': a comparative critical analysis of three consecutive decades of monopolar transurethral resection of the prostate (TURP) outcomes. BJU Int 2012; 110: 1595\u20131601.","journal-title":"BJU Int"},{"key":"BFpcan201633_CR25","doi-asserted-by":"publisher","first-page":"E896","DOI":"10.1111\/j.1464-410X.2012.11471.x","volume":"110","author":"JS Chen","year":"2012","unstructured":"Chen JS, Chen JS, Chang CH, Yang WH, Kao YH . Acute urinary retention increases the risk of complications after transurethral resection of the prostate: a population-based study. BJU Int 2012; 110: E896\u2013E901.","journal-title":"BJU Int"},{"key":"BFpcan201633_CR26","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1055\/s-0031-1275711","volume":"74","author":"F Hoffmann","year":"2012","unstructured":"Hoffmann F, Icks A . Structural differences between health insurance funds and their impact on health services research: results from the Bertelsmann Health-Care Monitor. Gesundheitswesen 2012; 74: 291\u2013297.","journal-title":"Gesundheitswesen"},{"key":"BFpcan201633_CR27","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1111\/bju.12281","volume":"113","author":"MI Omar","year":"2014","unstructured":"Omar MI, Lam TB, Alexander CE, Graham J, Mamoulakis C, Imamura M et al. Systematic review and meta-analysis of the clinical effectiveness of bipolar compared with monopolar transurethral resection of the prostate (TURP). BJU Int 2014; 113: 24\u201335.","journal-title":"BJU Int"},{"key":"BFpcan201633_CR28","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1111\/j.1464-410X.2010.09954.x","volume":"107","author":"S Gravas","year":"2011","unstructured":"Gravas S, Bachmann A, Reich O, Roehrborn CG, Gilling PJ, de la Rosette J . Critical review of lasers in benign prostatic hyperplasia (BPH). BJU Int 2011; 107: 1030\u20131043.","journal-title":"BJU Int"}],"container-title":["Prostate Cancer and Prostatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/pcan201633.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/pcan201633","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/pcan201633.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T21:08:55Z","timestamp":1648674535000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/pcan201633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,9]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["BFpcan201633"],"URL":"https:\/\/doi.org\/10.1038\/pcan.2016.33","relation":{},"ISSN":["1365-7852","1476-5608"],"issn-type":[{"value":"1365-7852","type":"print"},{"value":"1476-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,9]]},"assertion":[{"value":"4 April 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 June 2016","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2016","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 August 2016","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}