{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T20:09:36Z","timestamp":1771013376917,"version":"3.50.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2013,11,13]],"date-time":"2013-11-13T00:00:00Z","timestamp":1384300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2013,11,13]],"date-time":"2013-11-13T00:00:00Z","timestamp":1384300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Res"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1038\/pr.2013.219","type":"journal-article","created":{"date-parts":[[2013,11,13]],"date-time":"2013-11-13T16:53:51Z","timestamp":1384361631000},"page":"328-335","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effect of oxygen inhalation on cerebral blood flow velocity in premature neonates"],"prefix":"10.1038","volume":"75","author":[{"given":"Sriparna","family":"Basu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Barman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramchandra","family":"Shukla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashok","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,11,13]]},"reference":[{"key":"BFpr2013219_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0166-4328(05)80189-5","volume":"49","author":"LS de Vries","year":"1992","unstructured":"de Vries LS, Eken P, Dubowitz LM . The spectrum of leukomalacia using cranial ultrasound. Behav Brain Res 1992;49:1\u20136.","journal-title":"Behav Brain Res"},{"key":"BFpr2013219_CR2","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1016\/j.jpeds.2004.03.034","volume":"144","author":"LS De Vries","year":"2004","unstructured":"De Vries LS, Van Haastert IL, Rademaker KJ, Koopman C, Groenendaal F . Ultrasound abnormalities preceding cerebral palsy in high-risk preterm infants. J Pediatr 2004;144:815\u201320.","journal-title":"J Pediatr"},{"key":"BFpr2013219_CR3","doi-asserted-by":"publisher","first-page":"424","DOI":"10.3389\/fphys.2012.00424","volume":"3","author":"AA Baburamani","year":"2012","unstructured":"Baburamani AA, Ek CJ, Walker DW, Castillo-Melendez M . Vulnerability of the developing brain to hypoxic-ischemic damage: contribution of the cerebral vasculature to injury and repair? Front Physiol 2012;3:424.","journal-title":"Front Physiol"},{"key":"BFpr2013219_CR4","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1203\/00006450-198707000-00007","volume":"22","author":"BL Trommer","year":"1987","unstructured":"Trommer BL, Groothuis DR, Pasternak JF . Quantitative analysis of cerebral vessels in the newborn puppy: the structure of germinal matrix vessels may predispose to hemorrhage. Pediatr Res 1987;22:23\u20138.","journal-title":"Pediatr Res"},{"key":"BFpr2013219_CR5","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.3357\/ASEM.2177.2007","volume":"78","author":"N Nishimura","year":"2007","unstructured":"Nishimura N, Iwasaki K, Ogawa Y, Shibata S . Oxygen administration, cerebral blood flow velocity, and dynamic cerebral autoregulation. Aviat Space Environ Med 2007;78:1121\u20137.","journal-title":"Aviat Space Environ Med"},{"key":"BFpr2013219_CR6","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/1423-0127-17-14","volume":"17","author":"MA Macri","year":"2010","unstructured":"Macri MA, D\u2019Alessandro N, Di Giulio C, et al. Region-specific effects on brain metabolites of hypoxia and hyperoxia overlaid on cerebral ischemia in young and old rats: a quantitative proton magnetic resonance spectroscopy study. J Biomed Sci 2010;17:14.","journal-title":"J Biomed Sci"},{"key":"BFpr2013219_CR7","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1038\/sj.jcbfm.9600384","volume":"27","author":"K Iwasaki","year":"2007","unstructured":"Iwasaki K, Ogawa Y, Shibata S, Aoki K . Acute exposure to normobaric mild hypoxia alters dynamic relationships between blood pressure and blood flow at very low frequency. J Cereb Blood Flow Metab 2007;27:776\u201384.","journal-title":"J Cereb Blood Flow Metab"},{"key":"BFpr2013219_CR8","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1007\/BF02723151","volume":"70","author":"PK Riyas","year":"2003","unstructured":"Riyas PK, Vijayakumar KM, Kulkarni ML . Neonatal mechanical ventilation. Indian J Pediatr 2003;70:537\u201340.","journal-title":"Indian J Pediatr"},{"key":"BFpr2013219_CR9","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/0887-8994(92)90065-7","volume":"8","author":"A Kamei","year":"1992","unstructured":"Kamei A, Houdou S, Mito T, Konomi H, Takashima S . Developmental change in type VI collagen in human cerebral vessels. Pediatr Neurol 1992;8:183\u20136.","journal-title":"Pediatr Neurol"},{"key":"BFpr2013219_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1203\/PDR.0b013e3181c1b176","volume":"67","author":"P Ballabh","year":"2010","unstructured":"Ballabh P . Intraventricular hemorrhage in premature infants: mechanism of disease. Pediatr Res 2010;67:1\u20138.","journal-title":"Pediatr Res"},{"issue":"5 Pt 1","key":"BFpr2013219_CR11","doi-asserted-by":"publisher","first-page":"e590","DOI":"10.1542\/peds.111.5.e590","volume":"111","author":"N Linder","year":"2003","unstructured":"Linder N, Haskin O, Levit O, et al. Risk factors for intraventricular hemorrhage in very low birth weight premature infants: a retrospective case-control study. Pediatrics 2003;111(5 Pt 1):e590\u20135.","journal-title":"Pediatrics"},{"key":"BFpr2013219_CR12","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/S0887-8994(00)00239-3","volume":"24","author":"A Pellicer","year":"2001","unstructured":"Pellicer A, Valverde E, Gay\u00e1 F, Quero J, Caba\u00f1as F . Postnatal adaptation of brain circulation in preterm infants. Pediatr Neurol 2001;24:103\u20139.","journal-title":"Pediatr Neurol"},{"issue":"Pt 9","key":"BFpr2013219_CR13","first-page":"2033","volume":"587","author":"SJ Lee","year":"2009","unstructured":"Lee SJ, Hatran DP, Tomimatsu T, Pe\u00f1a JP, McAuley G, Longo LD . Fetal cerebral blood flow, electrocorticographic activity, and oxygenation: responses to acute hypoxia. J Physiol (Lond) 2009;587(Pt 9):2033\u201347.","journal-title":"J Physiol (Lond)"},{"key":"BFpr2013219_CR14","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1523\/JNEUROSCI.3213-07.2008","volume":"28","author":"B Gerstner","year":"2008","unstructured":"Gerstner B, DeSilva TM, Genz K, et al. Hyperoxia causes maturation-dependent cell death in the developing white matter. J Neurosci 2008;28:1236\u201345.","journal-title":"J Neurosci"},{"key":"BFpr2013219_CR15","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1159\/000327245","volume":"33","author":"G Vottier","year":"2011","unstructured":"Vottier G, Pham H, Pansiot J, et al. Deleterious effect of hyperoxia at birth on white matter damage in the newborn rat. Dev Neurosci 2011;33:261\u20139.","journal-title":"Dev Neurosci"},{"key":"BFpr2013219_CR16","doi-asserted-by":"publisher","first-page":"15089","DOI":"10.1073\/pnas.222550499","volume":"99","author":"P Bittigau","year":"2002","unstructured":"Bittigau P, Sifringer M, Genz K, et al. Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. Proc Natl Acad Sci USA 2002;99:15089\u201394.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"Pt 1","key":"BFpr2013219_CR17","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1113\/jphysiol.2006.119925","volume":"578","author":"JP Pena","year":"2007","unstructured":"Pena JP, Tomimatsu T, Hatran DP, McGill LL, Longo LD . Cerebral blood flow and oxygenation in ovine fetus: responses to superimposed hypoxia at both low and high altitude. J Physiol (Lond) 2007;578(Pt 1):359\u201370.","journal-title":"J Physiol (Lond)"},{"key":"BFpr2013219_CR18","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.earlhumdev.2010.01.029","volume":"86","author":"KD Liem","year":"2010","unstructured":"Liem KD, Greisen G . Monitoring of cerebral haemodynamics in newborn infants. Early Hum Dev 2010;86:155\u20138.","journal-title":"Early Hum Dev"},{"key":"BFpr2013219_CR19","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1152\/physrev.1959.39.2.183","volume":"39","author":"NA Lassen","year":"1959","unstructured":"Lassen NA . Cerebral blood flow and oxygen consumption in man. Physiol Rev 1959;39:183\u2013238.","journal-title":"Physiol Rev"},{"key":"BFpr2013219_CR20","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/978-1-4419-7756-4_31","volume":"701","author":"A Caicedo","year":"2011","unstructured":"Caicedo A, De Smet D, Vanderhaegen J, et al. Impaired cerebral autoregulation using near-infrared spectroscopy and its relation to clinical outcomes in premature infants. Adv Exp Med Biol 2011;701:233\u20139.","journal-title":"Adv Exp Med Biol"},{"key":"BFpr2013219_CR21","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/S0022-3476(79)80373-X","volume":"94","author":"HC Lou","year":"1979","unstructured":"Lou HC, Lassen NA, Friis-Hansen B . Impaired autoregulation of cerebral blood flow in the distressed newborn infant. J Pediatr 1979;94:118\u201321.","journal-title":"J Pediatr"},{"key":"BFpr2013219_CR22","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1542\/peds.106.4.625","volume":"106","author":"M Tsuji","year":"2000","unstructured":"Tsuji M, Saul JP, du Plessis A, et al. Cerebral intravascular oxygenation correlates with mean arterial pressure in critically ill premature infants. Pediatrics 2000;106:625\u201332.","journal-title":"Pediatrics"},{"key":"BFpr2013219_CR23","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1152\/japplphysiol.00656.2009","volume":"108","author":"N Nishimura","year":"2010","unstructured":"Nishimura N, Iwasaki K, Ogawa Y, Aoki K . Decreased steady-state cerebral blood flow velocity and altered dynamic cerebral autoregulation during 5-h sustained 15% O2 hypoxia. J Appl Physiol 2010;108:1154\u201361.","journal-title":"J Appl Physiol"},{"issue":"10 Spec No","key":"BFpr2013219_CR24","doi-asserted-by":"publisher","first-page":"1126","DOI":"10.1136\/adc.63.10_Spec_No.1126","volume":"63","author":"S Niijima","year":"1988","unstructured":"Niijima S, Shortland DB, Levene MI, Evans DH . Transient hyperoxia and cerebral blood flow velocity in infants born prematurely and at full term. Arch Dis Child 1988;63(10 Spec No):1126\u201330.","journal-title":"Arch Dis Child"},{"key":"BFpr2013219_CR25","first-page":"468","volume":"48","author":"FA Leahy","year":"1980","unstructured":"Leahy FA, Cates D, MacCallum M, Rigatto H . Effect of CO2 and 100% O2 on cerebral blood flow in preterm infants. J Appl Physiol Respir Environ Exerc Physiol 1980;48:468\u201372.","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"key":"BFpr2013219_CR26","doi-asserted-by":"publisher","first-page":"F15","DOI":"10.1136\/fn.81.1.F15","volume":"81","author":"JH Meek","year":"1999","unstructured":"Meek JH, Tyszczuk L, Elwell CE, Wyatt JS . Low cerebral blood flow is a risk factor for severe intraventricular haemorrhage. Arch Dis Child Fetal Neonatal Ed 1999;81:F15\u20138.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFpr2013219_CR27","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1542\/peds.68.6.763","volume":"68","author":"LR Ment","year":"1981","unstructured":"Ment LR, Ehrenkranz RA, Lange RC, Rothstein PT, Duncan CC . Alterations in cerebral blood flow in preterm infants with intraventricular hemorrhage. Pediatrics 1981;68:763\u20139.","journal-title":"Pediatrics"},{"key":"BFpr2013219_CR28","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1097\/01.PCC.0000112368.32965.45","volume":"5","author":"T Ojala","year":"2004","unstructured":"Ojala T, K\u00e4\u00e4p\u00e4 P, Helenius H, et al. Low cerebral blood flow resistance in nonventilated preterm infants predicts poor neurologic outcome. Pediatr Crit Care Med 2004;5:264\u20138.","journal-title":"Pediatr Crit Care Med"},{"key":"BFpr2013219_CR29","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1007\/s004310051034","volume":"158","author":"O Baenziger","year":"1999","unstructured":"Baenziger O, Mueller AM, Morales CG, et al. Cerebral blood flow and neurological outcome in the preterm infant. Eur J Pediatr 1999;158:138\u201343.","journal-title":"Eur J Pediatr"},{"key":"BFpr2013219_CR30","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1007\/s00431-011-1643-y","volume":"171","author":"S Basu","year":"2012","unstructured":"Basu S, Dewangan S, Shukla RC, Anupurva S, Kumar A . Cerebral blood flow velocity in early-onset neonatal sepsis and its clinical significance. Eur J Pediatr 2012;171:901\u20139.","journal-title":"Eur J Pediatr"},{"key":"BFpr2013219_CR31","doi-asserted-by":"publisher","first-page":"2288","DOI":"10.1007\/s10439-009-9763-5","volume":"37","author":"SJ Payne","year":"2009","unstructured":"Payne SJ, Selb J, Boas DA . Effects of autoregulation and CO2 reactivity on cerebral oxygen transport. Ann Biomed Eng 2009;37:2288\u201398.","journal-title":"Ann Biomed Eng"},{"key":"BFpr2013219_CR32","doi-asserted-by":"publisher","first-page":"F143","DOI":"10.1136\/adc.2005.092726","volume":"92","author":"W Tin","year":"2007","unstructured":"Tin W, Gupta S . Optimum oxygen therapy in preterm babies. Arch Dis Child Fetal Neonatal Ed 2007;92:F143\u20137.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFpr2013219_CR33","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1097\/JPN.0b013e318226ee2c","volume":"25","author":"C Deuber","year":"2011","unstructured":"Deuber C, Terhaar M . Hyperoxia in very preterm infants: a systematic review of the literature. J Perinat Neonatal Nurs 2011;25:268\u201374.","journal-title":"J Perinat Neonatal Nurs"},{"key":"BFpr2013219_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000322001","volume":"100","author":"OD Saugstad","year":"2011","unstructured":"Saugstad OD, Aune D . In search of the optimal oxygen saturation for extremely low birth weight infants: a systematic review and meta-analysis. Neonatology 2011;100:1\u20138.","journal-title":"Neonatology"},{"key":"BFpr2013219_CR35","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1038\/sj.jp.7211608","volume":"26","author":"R Deulofeut","year":"2006","unstructured":"Deulofeut R, Critz A, Adams-Chapman I, Sola A . Avoiding hyperoxia in infants < or = 1250\u2009g is associated with improved short- and long-term outcomes. J Perinatol 2006;26:700\u20135.","journal-title":"J Perinatol"},{"key":"BFpr2013219_CR36","doi-asserted-by":"publisher","first-page":"1959","DOI":"10.1056\/NEJMoa0911781","volume":"362","author":"SUPPORT Study Group of the Eunice Kennedy Shriver NICHD Neonatal Research Network.","year":"2010","unstructured":"SUPPORT Study Group of the Eunice Kennedy Shriver NICHD Neonatal Research Network. Target ranges of oxygen saturation in extremely preterm infants. N Engl J Med 2010;362:1959\u201369.","journal-title":"N Engl J Med"},{"key":"BFpr2013219_CR37","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.1056\/NEJMc1101319","volume":"364","author":"B Stenson","year":"2011","unstructured":"Stenson B, Brocklehurst P, Tarnow-Mordi W ; U.K. BOOST II trial; Australian BOOST II trial; New Zealand BOOST II trial. Increased 36-week survival with high oxygen saturation target in extremely preterm infants. N Engl J Med 2011;364:1680\u20132.","journal-title":"N Engl J Med"},{"key":"BFpr2013219_CR38","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1097\/00003246-199806000-00040","volume":"26","author":"BG Carter","year":"1998","unstructured":"Carter BG, Carlin JB, Tibballs J, Mead H, Hochmann M, Osborne A . Accuracy of two pulse oximeters at low arterial hemoglobin-oxygen saturation. Crit Care Med 1998;26:1128\u201333.","journal-title":"Crit Care Med"},{"key":"BFpr2013219_CR39","doi-asserted-by":"publisher","first-page":"F217","DOI":"10.1136\/fn.87.3.F217","volume":"87","author":"B Bohnhorst","year":"2002","unstructured":"Bohnhorst B, Peter CS, Poets CF . Detection of hyperoxaemia in neonates: data from three new pulse oximeters. Arch Dis Child Fetal Neonatal Ed 2002;87:F217\u20139.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFpr2013219_CR40","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1007\/BF01954276","volume":"154","author":"DP Cochran","year":"1995","unstructured":"Cochran DP, Shaw NJ . The use of pulse oximetry in the prevention of hyperoxaemia in preterm infants. Eur J Pediatr 1995;154:222\u20134.","journal-title":"Eur J Pediatr"},{"key":"BFpr2013219_CR41","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1177\/000992287000900607","volume":"9","author":"JJ Downes","year":"1970","unstructured":"Downes JJ, Vidyasagar D, Boggs TR Jr, Morrow GM 3rd . Respiratory distress syndrome of newborn infants. I. New clinical scoring system (RDS score) with acid\u2013base and blood-gas correlations. Clin Pediatr (Phila) 1970;9:325\u201331.","journal-title":"Clin Pediatr (Phila)"},{"key":"BFpr2013219_CR42","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/S0022-3476(05)82056-6","volume":"119","author":"JL Ballard","year":"1991","unstructured":"Ballard JL, Khoury JC, Wedig K, Wang L, Eilers-Walsman BL, Lipp R . New Ballard Score, expanded to include extremely premature infants. J Pediatr 1991;119:417\u201323.","journal-title":"J Pediatr"},{"key":"BFpr2013219_CR43","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/B978-1-4160-3995-2.10011-1","volume-title":"Neurology of the Newborn, 5th edn","author":"JJ Volpe","year":"2008","unstructured":"Volpe JJ . Intracranial hemorrhage: Germinal matrix-intraventricular hemorrhage of the preterm infant. In: Volpe JJ, ed. Neurology of the Newborn, 5th edn. Philadelphia, PA: Saunders Elsevier, 2008:517\u201388."},{"key":"BFpr2013219_CR44","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/B978-0-7216-0631-6.50009-9","volume-title":"Introduction to Vascular Ultrasonography, 5th edn","author":"WJ Zwibel","year":"2005","unstructured":"Zwibel WJ, Pellerito JS . Basic concepts of Doppler frequency spectrum analysis and ultrasound blood flow imaging. In: Zwibel WJ, Pellerito JS, eds. Introduction to Vascular Ultrasonography, 5th edn. Philadelphia, PA: Saunders Elsevier, 2005:61\u201389."}],"container-title":["Pediatric Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/pr2013219.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/pr2013219","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/pr2013219.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T04:59:11Z","timestamp":1684472351000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/pr2013219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,13]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["BFpr2013219"],"URL":"https:\/\/doi.org\/10.1038\/pr.2013.219","relation":{},"ISSN":["0031-3998","1530-0447"],"issn-type":[{"value":"0031-3998","type":"print"},{"value":"1530-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,13]]},"assertion":[{"value":"30 October 2012","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2013","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 November 2013","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}