{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:22:31Z","timestamp":1790785351448,"version":"4.1.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,4,19]],"date-time":"2013-04-19T00:00:00Z","timestamp":1366329600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Res"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1038\/pr.2013.67","type":"journal-article","created":{"date-parts":[[2013,4,19]],"date-time":"2013-04-19T11:58:13Z","timestamp":1366372693000},"page":"54-60","source":"Crossref","is-referenced-by-count":43,"title":["The effect of hematocrit on the efficacy of phototherapy for neonatal jaundice"],"prefix":"10.1038","volume":"74","author":[{"given":"Angelo A.","family":"Lamola","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod K.","family":"Bhutani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald J.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David K.","family":"Stevenson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antony F.","family":"McDonagh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,4,19]]},"reference":[{"key":"BFpr201367_CR1","first-page":"374","volume-title":"Advances in Optical Imaging and Photon Migration","author":"SL Jacques","year":"1996","unstructured":"Jacques SL . Origins of tissue optical properties in the UVA, visible, and NIR regions. In: Afano RR, Fujimoto JG, eds. Advances in Optical Imaging and Photon Migration. Oregon: Optical Society of America TOPS Proceedings, 1996:374\u201369."},{"key":"BFpr201367_CR2","first-page":"35","volume-title":"Solar Radiation and Human Health","author":"KP Nielson","year":"2008","unstructured":"Nielson KP, Zhao L, Stamnes JJ, Stamnes K, Moan J . The optics of human skin: aspects important for human health. In: Bjertness E, ed. Solar Radiation and Human Health. Oslo: Norwegian Academy of Science and Letters, 2008:35\u201346."},{"key":"BFpr201367_CR3","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/1011-1344(93)80063-F","volume":"18","author":"G Agati","year":"1993","unstructured":"Agati G, Fusi F, Donzelli GP, Pratesi R . Quantum yield and skin filtering effects on the formation rate of lumirubin. J Photochem Photobiol B, Biol 1993;18:197\u2013203.","journal-title":"J Photochem Photobiol B, Biol"},{"key":"BFpr201367_CR4","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1111\/j.1751-1097.1984.tb04557.x","volume":"40","author":"R Pratesi","year":"1984","unstructured":"Pratesi R, Ronchi L, Cecchi G, et al. Skin optics and phototherapy of jaundice. Photochem Photobiol 1984;40:77\u201383.","journal-title":"Photochem Photobiol"},{"key":"BFpr201367_CR5","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1111\/j.1651-2227.2007.00261.x","volume":"96","author":"F Ebbesen","year":"2007","unstructured":"Ebbesen F, Madsen P, St\u00f8vring S, Hundborg H, Agati G . Therapeutic effect of turquoise versus blue light with equal irradiance in preterm infants with jaundice. Acta Paediatr 2007;96:837\u201341.","journal-title":"Acta Paediatr"},{"key":"BFpr201367_CR6","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1038\/sj.jp.7210862","volume":"23","author":"DS Seidman","year":"2003","unstructured":"Seidman DS, Moise J, Ergaz Z, et al. A prospective randomized controlled study of phototherapy using blue and blue-green light-emitting devices, and conventional halogen-quartz phototherapy. J Perinatol 2003;23:123\u20137.","journal-title":"J Perinatol"},{"key":"BFpr201367_CR7","unstructured":"Lucey JF, Hewitt J . Recent observations on light and neonatal jaundice. In: Brown AK, Showacre J, eds. Phototherapy for Neonatal Jaundice DHEW Publication No (NIH). 1974:76\u20131075."},{"key":"BFpr201367_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000241630","volume":"43","author":"B Granati","year":"1983","unstructured":"Granati B, Felice M, Fortunato A, Giancola G, Rubaltelli FF . Sites of action of light during phototherapy. Biol Neonate 1983;43:1\u20138.","journal-title":"Biol Neonate"},{"key":"BFpr201367_CR9","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1117\/12.275465","volume":"2975","author":"SL Jacques","year":"1997","unstructured":"Jacques SL, Saidi IS, Ladner A, Oelberg, D . Developing an optical fiber reflectance spectrometer to monitor bilirubinemia in neonates. Proc SPIE 1997;2975:115\u201324.","journal-title":"Proc SPIE"},{"key":"BFpr201367_CR10","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1117\/12.184904","volume":"2128","author":"SL Jacques","year":"1994","unstructured":"Jacques SL, Saidi IS, Tittel FK . Average depth of blood vessels in skin and lesions deduced by optical fiber spectroscopy. Proc SPIE 1994;2128:231\u20137.","journal-title":"Proc SPIE"},{"key":"BFpr201367_CR11","volume-title":"A Study on Skin Optics","author":"A Krishnaswamy","year":"2004","unstructured":"Krishnaswamy A, Baranoski VG . A Study on Skin Optics. Canada: School of Computer Science University of Waterloo, 2004; report CS-2004-01."},{"key":"BFpr201367_CR12","doi-asserted-by":"publisher","first-page":"7410","DOI":"10.1364\/AO.34.007410","volume":"34","author":"IS Saidi","year":"1995","unstructured":"Saidi IS, Jacques SL, Tittel FK . Mie and Rayleigh modeling of visible-light scattering in neonatal skin. Appl Opt 1995;34:7410\u20138.","journal-title":"Appl Opt"},{"key":"BFpr201367_CR13","volume-title":"Tissue Optics\u2014Light Scattering and Instruments for Medical Diagnosis, 2nd edn","author":"V Tuchin","year":"2007","unstructured":"Tuchin V . Tissue Optics\u2014Light Scattering and Instruments for Medical Diagnosis, 2nd edn. Bellingham, WA: Society of Photographic Instrumentation Engineers, 2007."},{"key":"BFpr201367_CR14","doi-asserted-by":"publisher","first-page":"1452","DOI":"10.1046\/j.0022-202x.2001.01577.x","volume":"117","author":"G Zonios","year":"2001","unstructured":"Zonios G, Bykowski J, Kollias N . Skin melanin, hemoglobin, and light scattering properties can be quantitatively assessed in vivo using diffuse reflectance spectroscopy. J Invest Dermatol 2001;117:1452\u20137.","journal-title":"J Invest Dermatol"},{"key":"BFpr201367_CR15","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/S0095-5108(18)30579-7","volume":"17","author":"JF Ennever","year":"1990","unstructured":"Ennever JF . Blue light, green light, white light, more light: treatment of neonatal jaundice. Clin Perinatol 1990;17:467\u201381.","journal-title":"Clin Perinatol"},{"key":"BFpr201367_CR16","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1111\/j.1751-1097.1989.tb04164.x","volume":"50","author":"AF McDonagh","year":"1989","unstructured":"McDonagh AF, Agati G, Fusi F, Pratesi R . Quantum yields for laser photocyclization of bilirubin in the presence of human serum albumin. Dependence of quantum yield on excitation wavelength. Photochem Photobiol 1989;50:305\u201319.","journal-title":"Photochem Photobiol"},{"key":"BFpr201367_CR17","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1136\/adc.64.4.605","volume":"64","author":"A Knudsen","year":"1989","unstructured":"Knudsen A, Brodersen R . Skin colour and bilirubin in neonates. Arch Dis Child 1989;64:605\u20139.","journal-title":"Arch Dis Child"},{"key":"BFpr201367_CR18","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/0003-2697(79)90105-2","volume":"100","author":"AA Lamola","year":"1979","unstructured":"Lamola AA, Eisinger J, Blumberg WE, Patel SC, Flores J . Flurorometric study of the partition of bilirubin among blood components: basis for rapid microassays of bilirubin and bilirubin binding capacity in whole blood. Anal Biochem 1979;100:25\u201342.","journal-title":"Anal Biochem"},{"key":"BFpr201367_CR19","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1373\/clinchem.2008.121269","volume":"55","author":"CE Ahlfors","year":"2009","unstructured":"Ahlfors CE, Wennberg RP, Ostrow JD, Tiribelli C . Unbound (free) bilirubin: improving the paradigm for evaluating neonatal jaundice. Clin Chem 2009;55:1288\u201399.","journal-title":"Clin Chem"},{"key":"BFpr201367_CR20","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1542\/peds.65.2.195","volume":"65","author":"I Yamanouchi","year":"1980","unstructured":"Yamanouchi I, Yamauchi Y, Igarashi I . Transcutaneous bilirubinometry: preliminary studies of noninvasive transcutaneous bilirubin meter in the Okayama National Hospital. Pediatrics 1980;65:195\u2013202.","journal-title":"Pediatrics"},{"key":"BFpr201367_CR21","doi-asserted-by":"publisher","first-page":"e1046","DOI":"10.1542\/peds.2011-1494","volume":"128","author":"VK Bhutani","year":"2011","unstructured":"Bhutani VK ; Committee on Fetus and Newborn; American Academy of Pediatrics. Phototherapy to prevent severe neonatal hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics 2011;128:e1046\u201352.","journal-title":"Pediatrics"},{"key":"BFpr201367_CR22","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1203\/PDR.0b013e3181dcedc0","volume":"67","author":"K Mreihil","year":"2010","unstructured":"Mreihil K, McDonagh AF, Nakstad B, Hansen TW . Early isomerization of bilirubin in phototherapy of neonatal jaundice. Pediatr Res 2010;67:656\u20139.","journal-title":"Pediatr Res"},{"key":"BFpr201367_CR23","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1001\/archpedi.156.7.669","volume":"156","author":"MJ Maisels","year":"2002","unstructured":"Maisels MJ, Kring E . Rebound in serum bilirubin level following intensive phototherapy. Arch Pediatr Adolesc Med 2002;156:669\u201372.","journal-title":"Arch Pediatr Adolesc Med"},{"key":"BFpr201367_CR24","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1136\/adc.2005.081224","volume":"91","author":"M Kaplan","year":"2006","unstructured":"Kaplan M, Kaplan E, Hammerman C, et al. Post-phototherapy neonatal bilirubin rebound: a potential cause of significant hyperbilirubinaemia. Arch Dis Child 2006;91:31\u20134.","journal-title":"Arch Dis Child"},{"key":"BFpr201367_CR25","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1111\/j.1751-1097.1992.tb04226.x","volume":"55","author":"G Agati","year":"1992","unstructured":"Agati G, Fusi F, Pratesi R, McDonagh AF . Wavelength-dependent quantum yield for Z\u2014E isomerization of bilirubin complexed with human serum albumin. Photochem Photobiol 1992;55:185\u201390.","journal-title":"Photochem Photobiol"},{"key":"BFpr201367_CR26","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1055\/s-2008-1040549","volume":"8","author":"AF McDonagh","year":"1988","unstructured":"McDonagh AF, Lightner DA . Phototherapy and the photobiology of bilirubin. Semin Liver Dis 1988;8:272\u201383.","journal-title":"Semin Liver Dis"},{"key":"BFpr201367_CR27","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1053\/j.semperi.2011.02.015","volume":"35","author":"VK Bhutani","year":"2011","unstructured":"Bhutani VK, Cline BK, Donaldson KM, Vreman HJ . The need to implement effective phototherapy in resource-constrained settings. Semin Perinatol 2011;35:192\u20137.","journal-title":"Semin Perinatol"},{"key":"BFpr201367_CR28","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1111\/1523-1747.ep12479191","volume":"77","author":"RR Anderson","year":"1981","unstructured":"Anderson RR, Parrish JA . The optics of human skin. J Invest Dermatol 1981;77:13\u20139.","journal-title":"J Invest Dermatol"},{"key":"BFpr201367_CR29","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1038\/sj.jp.7211789","volume":"27","author":"MJ Maisels","year":"2007","unstructured":"Maisels MJ, Kring EA, DeRidder J . Randomized controlled trial of light-emitting diode phototherapy. J Perinatol 2007;27:565\u20137.","journal-title":"J Perinatol"},{"key":"BFpr201367_CR30","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1038\/jp.2012.39","volume":"33","author":"BH Morris","year":"2013","unstructured":"Morris BH, Tyson JE, Stevenson DK, et al. Efficacy of phototherapy devices and outcomes among extremely low birth weight infants: multi-center observational study. J Perinatol 2013;33:126\u201333.","journal-title":"J Perinatol"},{"key":"BFpr201367_CR31","doi-asserted-by":"publisher","first-page":"1885","DOI":"10.1056\/NEJMoa0803024","volume":"359","author":"BH Morris","year":"2008","unstructured":"Morris BH, Oh W, Tyson JE, et al.; NICHD Neonatal Research Network. Aggressive vs. conservative phototherapy for infants with extremely low birth weight. N Engl J Med 2008;359:1885\u201396.","journal-title":"N Engl J Med"},{"key":"BFpr201367_CR32","first-page":"153","volume":"21","author":"G Gathwala","year":"2002","unstructured":"Gathwala G, Sharma S . Phototherapy induces oxidative stress in premature neonates. Indian J Gastroenterol 2002;21:153\u20134.","journal-title":"Indian J Gastroenterol"},{"key":"BFpr201367_CR33","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1007\/BF02726223","volume":"67","author":"G Gathwala","year":"2000","unstructured":"Gathwala G, Sharma S . Oxidative stress, phototherapy and the neonate. Indian J Pediatr 2000;67:805\u20138.","journal-title":"Indian J Pediatr"},{"key":"BFpr201367_CR34","first-page":"319","volume":"83","author":"A Aycicek","year":"2007","unstructured":"Aycicek A, Erel O . Total oxidant\/antioxidant status in jaundiced newborns before and after phototherapy. J Pediatr (Rio J) 2007;83:319\u201322.","journal-title":"J Pediatr (Rio J)"},{"key":"BFpr201367_CR35","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/S0022-3476(77)80784-1","volume":"90","author":"DS Gromisch","year":"1977","unstructured":"Gromisch DS, Lopez R, Cole HS, Cooperman JM . Light (phototherapy)\u2013induced riboflavin deficiency in the neonate. J Pediatr 1977;90:118\u201322.","journal-title":"J Pediatr"},{"key":"BFpr201367_CR36","first-page":"108","volume":"37","author":"E Knobloch","year":"1988","unstructured":"Knobloch E, Hodr R, Houdkov\u00e1 V . [Spectrofluorimetric determination of FAD, FMN and free riboflavin in the blood]. Cesk Farm 1988;37:108\u201311.","journal-title":"Cesk Farm"},{"key":"BFpr201367_CR37","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1542\/peds.2011-2586","volume":"129","author":"N Bosschaart","year":"2012","unstructured":"Bosschaart N, Kok JH, Newsum AM, et al. Limitations and opportunities of transcutaneous bilirubin measurements. Pediatrics 2012;129:689\u201394.","journal-title":"Pediatrics"},{"key":"BFpr201367_CR38","unstructured":"Prahl S,Oregon Medical Laser Center. Tabulated molar extinction coefficient for hemoglobin in water. Oregon Medical Laser Center, 1999. ( http:\/\/omlc.ogi.edu\/spectra\/hemoglobin\/summary.html .)"},{"key":"BFpr201367_CR39","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1093\/clinchem\/37.9.1633","volume":"37","author":"WG Zijlstra","year":"1991","unstructured":"Zijlstra WG, Buursma A, Meeuwsen-van der Roest WP . Absorption spectra of human fetal and adult oxyhemoglobin, de-oxyhemoglobin, carboxyhemoglobin, and methemoglobin. Clin Chem 1991;37:1633\u20138.","journal-title":"Clin Chem"},{"key":"BFpr201367_CR40","first-page":"31","volume-title":"Melanin: Its Role in Human Photoprotection","author":"N Kollias","year":"1995","unstructured":"Kollias N . The spectroscopy of human melanin pigmentation. In: Melanin: Its Role in Human Photoprotection. Overland Park, KS: Valdenmar, 1995:31\u20138."},{"key":"BFpr201367_CR41","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1111\/j.1651-2227.2007.00631.x","volume":"97","author":"HJ Vreman","year":"2008","unstructured":"Vreman HJ, Wong RJ, Murdock JR, Stevenson DK . Standardized bench method for evaluating the efficacy of phototherapy devices. Acta Paediatr 2008;97:308\u201316.","journal-title":"Acta Paediatr"},{"key":"BFpr201367_CR42","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1053\/j.semperi.2004.09.003","volume":"28","author":"HJ Vreman","year":"2004","unstructured":"Vreman HJ, Wong RJ, Stevenson DK . Phototherapy: current methods and future directions. Semin Perinatol 2004;28:326\u201333.","journal-title":"Semin Perinatol"},{"key":"BFpr201367_CR43","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1203\/00006450-199811000-00027","volume":"44","author":"HJ Vreman","year":"1998","unstructured":"Vreman HJ, Wong RJ, Stevenson DK, et al. Light-emitting diodes: a novel light source for phototherapy. Pediatr Res 1998;44:804\u20139.","journal-title":"Pediatr Res"}],"container-title":["Pediatric Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/pr201367.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/pr201367","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/pr201367.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T01:00:26Z","timestamp":1684458026000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/pr201367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,19]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["BFpr201367"],"URL":"https:\/\/doi.org\/10.1038\/pr.2013.67","relation":{},"ISSN":["0031-3998","1530-0447"],"issn-type":[{"value":"0031-3998","type":"print"},{"value":"1530-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,19]]}}}