{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T13:54:52Z","timestamp":1792418092289,"version":"4.4.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2015,8,13]],"date-time":"2015-08-13T00:00:00Z","timestamp":1439424000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Res"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1038\/pr.2015.153","type":"journal-article","created":{"date-parts":[[2015,8,13]],"date-time":"2015-08-13T16:43:26Z","timestamp":1439484206000},"page":"678-682","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Evaluation of kidney dysfunction and angiotensinogen as an early novel biomarker of intrauterine growth restricted offspring rats"],"prefix":"10.1038","volume":"78","author":[{"given":"Yayoi","family":"Murano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoto","family":"Nishizaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amane","family":"Endo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naho","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomonosuke","family":"Someya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayu","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taichi","family":"Hara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Sakuraya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Hara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daishi","family":"Hirano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuyoshi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromichi","family":"Shoji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuichiro","family":"Fujinaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Ohtomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,8,13]]},"reference":[{"key":"BFpr2015153_CR1","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1126\/science.1095292","volume":"305","author":"PD Gluckman","year":"2004","unstructured":"Gluckman PD, Hanson MA. Living with the past: evolution, development, and patterns of disease. Science 2004;305:1733\u20136.","journal-title":"Science"},{"key":"BFpr2015153_CR2","doi-asserted-by":"publisher","first-page":"S68","DOI":"10.1111\/j.1523-1755.2005.09712.x","volume":"68","author":"VA Luyckx","year":"2005","unstructured":"Luyckx VA, Brenner BM. Low birth weight, nephron number, and kidney disease. Kidney Int 2005;68:S68\u201377.","journal-title":"Kidney Int"},{"key":"BFpr2015153_CR3","doi-asserted-by":"publisher","first-page":"F288","DOI":"10.1152\/ajprenal.00564.2010","volume":"301","author":"K Lim","year":"2011","unstructured":"Lim K, Lombardo P, Schneider-Kolsky M, Hilliard L, Denton KM, Black MJ. Induction of hyperglycemia in adult intrauterine growth-restricted rats: effects on renal function. Am J Physiol Renal Physiol 2011;301:F288\u201394.","journal-title":"Am J Physiol Renal Physiol"},{"key":"BFpr2015153_CR4","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1007\/s00467-009-1437-x","volume":"25","author":"Q Shen","year":"2010","unstructured":"Shen Q, Xu H, Wei LM, Chen J, Liu HM, Guo W. A comparative proteomic study of nephrogenesis in intrauterine growth restriction. Pediatr Nephrol 2010;25:1063\u201372.","journal-title":"Pediatr Nephrol"},{"key":"BFpr2015153_CR5","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1016\/j.nut.2010.03.003","volume":"27","author":"Q Shen","year":"2011","unstructured":"Shen Q, Xu H, Wei LM, Chen J, Liu HM. Intrauterine growth restriction and postnatal high-protein diet affect the kidneys in adult rats. Nutrition 2011;27:364\u201371.","journal-title":"Nutrition"},{"key":"BFpr2015153_CR6","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1111\/j.1549-8719.2011.00089.x","volume":"18","author":"U Neitzke","year":"2011","unstructured":"Neitzke U, Harder T, Plagemann A. Intrauterine growth restriction and developmental programming of the metabolic syndrome: a critical appraisal. Microcirculation 2011;18:304\u201311.","journal-title":"Microcirculation"},{"key":"BFpr2015153_CR7","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1038\/pr.2012.114","volume":"72","author":"S Kusuda","year":"2012","unstructured":"Kusuda S, Fujimura M, Uchiyama A, Totsu S, Matsunami K ; Neonatal Research Network, Japan. Trends in morbidity and mortality among very-low-birth-weight infants from 2003 to 2008 in Japan. Pediatr Res 2012;72:531\u20138.","journal-title":"Pediatr Res"},{"key":"BFpr2015153_CR8","doi-asserted-by":"publisher","first-page":"1168","DOI":"10.1542\/peds.2013-0009","volume":"131","author":"JB Carmody","year":"2013","unstructured":"Carmody JB, Charlton JR. Short-term gestation, long-term risk: prematurity and chronic kidney disease. Pediatrics 2013;131:1168\u201379.","journal-title":"Pediatrics"},{"key":"BFpr2015153_CR9","doi-asserted-by":"publisher","first-page":"e429","DOI":"10.1111\/apa.12324","volume":"102","author":"K Taranta-Janusz","year":"2013","unstructured":"Taranta-Janusz K, Wasilewska A, D\u0119bek W, Fi\u0142onowicz R, Michaluk-Skutnik J. Urinary angiotensinogen as a novel marker of obstructive nephropathy in children. Acta Paediatr 2013;102:e429\u201333.","journal-title":"Acta Paediatr"},{"key":"BFpr2015153_CR10","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1097\/MAJ.0b013e3181b90c25","volume":"338","author":"T Saito","year":"2009","unstructured":"Saito T, Urushihara M, Kotani Y, Kagami S, Kobori H. Increased urinary angiotensinogen is precedent to increased urinary albumin in patients with type 1 diabetes. Am J Med Sci 2009;338:478\u201380.","journal-title":"Am J Med Sci"},{"key":"BFpr2015153_CR11","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.bbrc.2007.04.105","volume":"358","author":"H Kobori","year":"2007","unstructured":"Kobori H, Katsurada A, Ozawa Y, et al. Enhanced intrarenal oxidative stress and angiotensinogen in IgA nephropathy patients. Biochem Biophys Res Commun 2007;358:156\u201363.","journal-title":"Biochem Biophys Res Commun"},{"key":"BFpr2015153_CR12","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1161\/HYPERTENSIONAHA.110.166843","volume":"58","author":"Y Konishi","year":"2011","unstructured":"Konishi Y, Nishiyama A, Morikawa T, et al. Relationship between urinary angiotensinogen and salt sensitivity of blood pressure in patients with IgA nephropathy. Hypertension 2011;58:205\u201311.","journal-title":"Hypertension"},{"key":"BFpr2015153_CR13","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1007\/s10157-013-0896-3","volume":"18","author":"N Nishizaki","year":"2014","unstructured":"Nishizaki N, Hirano D, Nishizaki Y, et al. Increased urinary angiotensinogen is an effective marker of chronic renal impairment in very low birth weight children. Clin Exp Nephrol 2014;18:642\u20138.","journal-title":"Clin Exp Nephrol"},{"key":"BFpr2015153_CR14","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1203\/00006450-200104000-00005","volume":"49","author":"LL Woods","year":"2001","unstructured":"Woods LL, Ingelfinger JR, Nyengaard JR, Rasch R. Maternal protein restriction suppresses the newborn renin-angiotensin system and programs adult hypertension in rats. Pediatr Res 2001;49:460\u20137.","journal-title":"Pediatr Res"},{"key":"BFpr2015153_CR15","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1254\/jphs.12076FP","volume":"119","author":"M Kamiyama","year":"2012","unstructured":"Kamiyama M, Zsombok A, Kobori H. Urinary angiotensinogen as a novel early biomarker of intrarenal renin-angiotensin system activation in experimental type 1 diabetes. J Pharmacol Sci 2012;119:314\u201323.","journal-title":"J Pharmacol Sci"},{"key":"BFpr2015153_CR16","doi-asserted-by":"publisher","first-page":"378","DOI":"10.4236\/ijcm.2011.24064","volume":"2","author":"M Urushihara","year":"2011","unstructured":"Urushihara M, Kobori H. Angiotensinogen expression is enhanced in the progression of glomerular disease. Int J Clin Med 2011;2:378\u201387.","journal-title":"Int J Clin Med"},{"key":"BFpr2015153_CR17","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.semnephrol.2004.01.003","volume":"24","author":"JJ Dillion","year":"2004","unstructured":"Dillion JJ. Angiotensinogen-converting enzyme inhibitors and angiotensinogen receptor blockers for IgA nephropathy. Semin Nephrol 2004;24:218\u201324.","journal-title":"Semin Nephrol"},{"key":"BFpr2015153_CR18","doi-asserted-by":"publisher","first-page":"1510","DOI":"10.1046\/j.1523-1755.1998.00138.x","volume":"54","author":"CK Fujihara","year":"1998","unstructured":"Fujihara CK, Malheiros DM, Zatz R, Noronha IL. Mycophenolate mofetil attenuates renal injury in the rat remnant kidney. Kidney Int 1998;54:1510\u20139.","journal-title":"Kidney Int"},{"key":"BFpr2015153_CR19","doi-asserted-by":"publisher","first-page":"1913","DOI":"10.1111\/j.1523-1755.2005.00290.x","volume":"67","author":"CK Fujihara","year":"2005","unstructured":"Fujihara CK, Velho M, Malheiros DM, Zatz R. An extremely high dose of losartan affords superior renoprotection in the remnant model. Kidney Int 2005;67:1913\u201324.","journal-title":"Kidney Int"},{"key":"BFpr2015153_CR20","doi-asserted-by":"publisher","first-page":"2073","DOI":"10.1681\/ASN.2004080676","volume":"16","author":"H Kobori","year":"2005","unstructured":"Kobori H, Ozawa Y, Suzaki Y, Nishiyama A. Enhanced intrarenal angiotensinogen contributes to early renal injury in spontaneously hypertensive rats. J Am Soc Nephrol 2005;16:2073\u201380.","journal-title":"J Am Soc Nephrol"},{"key":"BFpr2015153_CR21","doi-asserted-by":"publisher","first-page":"71","DOI":"10.2215\/CJN.01700408","volume":"4","author":"JB Hodgin","year":"2009","unstructured":"Hodgin JB, Rasoulpour M, Markowitz GS, D\u2019Agati VD. Very low birth weight is a risk factor for secondary focal segmental glomerulosclerosis. Clin J Am Soc Nephrol 2009;4:71\u20136.","journal-title":"Clin J Am Soc Nephrol"},{"key":"BFpr2015153_CR22","doi-asserted-by":"publisher","first-page":"1774","DOI":"10.1038\/ki.1996.265","volume":"49","author":"BM Brenner","year":"1996","unstructured":"Brenner BM, Lawler EV, Mackenzie HS. The hyperfiltration theory: a paradigm shift in nephrology. Kidney Int 1996;49:1774\u20137.","journal-title":"Kidney Int"},{"key":"BFpr2015153_CR23","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1038\/ki.1992.165","volume":"41","author":"PH Lane","year":"1992","unstructured":"Lane PH, Steffes MW, Mauer SM. Estimation of glomerular volume: a comparison of four methods. Kidney Int 1992;41:1085\u20139.","journal-title":"Kidney Int"},{"key":"BFpr2015153_CR24","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1038\/ki.1989.35","volume":"35","author":"Y Yoshida","year":"1989","unstructured":"Yoshida Y, Fogo A, Ichikawa I. Glomerular hemodynamic changes vs. hypertrophy in experimental glomerular sclerosis. Kidney Int 1989;35:654\u201360.","journal-title":"Kidney Int"}],"container-title":["Pediatric Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/pr2015153.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/pr2015153","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/pr2015153.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T20:57:51Z","timestamp":1684616271000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/pr2015153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,13]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["BFpr2015153"],"URL":"https:\/\/doi.org\/10.1038\/pr.2015.153","relation":{},"ISSN":["0031-3998","1530-0447"],"issn-type":[{"value":"0031-3998","type":"print"},{"value":"1530-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,13]]},"assertion":[{"value":"12 November 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}