{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:08:10Z","timestamp":1788412090688,"version":"build-2803163510"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T00:00:00Z","timestamp":1525824000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T00:00:00Z","timestamp":1525824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Res"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1038\/pr.2018.47","type":"journal-article","created":{"date-parts":[[2018,4,6]],"date-time":"2018-04-06T16:01:06Z","timestamp":1523030466000},"page":"1146-1151","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Maternal body mass index and risk of intraventricular hemorrhage in preterm infants"],"prefix":"10.1038","volume":"83","author":[{"given":"Vidya V","family":"Pai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzan L","family":"Carmichael","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiyi","family":"Kan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie A","family":"Leonard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry C","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,5,9]]},"reference":[{"key":"BFpr201847_CR1","doi-asserted-by":"publisher","first-page":"e450.e1","DOI":"10.1016\/j.ajog.2013.12.024","volume":"210","author":"JA Bastek","year":"2014","unstructured":"Bastek JA, Weber AL, McShea MA, Ryan ME, Elovitz MA . Prenatal inflammation is associated with adverse neonatal outcomes. Am J Obstet Gynecol 2014;210:e450.e1\u201310.","journal-title":"Am J Obstet Gynecol"},{"key":"BFpr201847_CR2","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1111\/ppe.12317","volume":"30","author":"S Cnattingius","year":"2016","unstructured":"Cnattingius S, Wikstr\u00f6m AK, Stephansson O, Johansson K . The impact of small for gestational age births in early and late preeclamptic pregnancies for preeclampsia recurrence: a cohort study of successive pregnancies in Sweden. Paediatr Perinat Epidemiol. 2016;30:563\u2013570.","journal-title":"Paediatr Perinat Epidemiol."},{"key":"BFpr201847_CR3","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1016\/S1701-2163(15)30879-3","volume":"35","author":"JM Crane","year":"2013","unstructured":"Crane JM, Murphy P, Burrage L, Hutchens D . Maternal and perinatal outcomes of extreme obesity in pregnancy. J Obstet Gynaecol Can 2013;35:606\u2013611.","journal-title":"J Obstet Gynaecol Can"},{"key":"BFpr201847_CR4","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/j.bpobgyn.2014.10.009","volume":"29","author":"L Santangeli","year":"2015","unstructured":"Santangeli L, Sattar N, Huda SS . Impact of maternal obesity on perinatal and childhood outcomes. Best Pract Res Clin Obstet Gynaecol 2015;29:438\u2013448.","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"BFpr201847_CR5","doi-asserted-by":"publisher","first-page":"2001","DOI":"10.1111\/1471-0528.14027","volume":"123","author":"AI Girsen","year":"2016","unstructured":"Girsen AI, Mayo JA, Carmichael SL et al. Medicine MoDPRCaSUSo Women's prepregnancy underweight as a risk factor for preterm birth: a retrospective study. BJOG 2016;123:2001\u20132007.","journal-title":"BJOG"},{"key":"BFpr201847_CR6","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1186\/2047-783X-14-2-55","volume":"14","author":"P Kalk","year":"2009","unstructured":"Kalk P, Guthmann F, Krause K et al. Impact of maternal body mass index on neonatal outcome. Eur J Med Res 2009;14:216\u2013222.","journal-title":"Eur J Med Res"},{"key":"BFpr201847_CR7","doi-asserted-by":"publisher","first-page":"e421","DOI":"10.1016\/j.ajog.2013.12.011","volume":"210","author":"AM Lynch","year":"2014","unstructured":"Lynch AM, Hart JE, Agwu OC, Fisher BM, West NA, Gibbs RS . Association of extremes of prepregnancy BMI with the clinical presentations of preterm birth. Am J Obstet Gynecol 2014;210:e421\u2013e429.","journal-title":"Am J Obstet Gynecol"},{"key":"BFpr201847_CR8","doi-asserted-by":"publisher","first-page":"c3428","DOI":"10.1136\/bmj.c3428","volume":"341","author":"SD McDonald","year":"2010","unstructured":"McDonald SD, Han Z, Mulla S, Beyene J, Group KS . Overweight and obesity in mothers and risk of preterm birth and low birth weight infants: systematic review and meta-analyses. BMJ 2010;341:c3428.","journal-title":"BMJ"},{"key":"BFpr201847_CR9","doi-asserted-by":"publisher","first-page":"159","DOI":"10.3233\/NPM-16915100","volume":"9","author":"R Singh","year":"2016","unstructured":"Singh R, Shah B, Allred EN et al. The antecedents and correlates of necrotizing enterocolitis and spontaneous intestinal perforation among infants born before the 28th week of gestation. J Neonatal Perinatal Med 2016;9:159\u2013170.","journal-title":"J Neonatal Perinatal Med"},{"key":"BFpr201847_CR10","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1038\/pr.2017.90","volume":"82","author":"SL Carmichael","year":"2017","unstructured":"Carmichael SL, Kan P, Gould JB, Stevenson DK, Shaw GM, Lee HC . Maternal prepregnancy body mass index and risk of bronchopulmonary dysplasia. Pediatr Res. 2017;82:8\u201313.","journal-title":"Pediatr Res."},{"key":"BFpr201847_CR11","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1542\/peds.2011-1796","volume":"129","author":"JB Helderman","year":"2012","unstructured":"Helderman JB, O'Shea TM, Kuban KC et al. Antenatal antecedents of cognitive impairment at 24 months in extremely low gestational age newborns. Pediatrics 2012;129:494\u2013502.","journal-title":"Pediatrics"},{"key":"BFpr201847_CR12","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1111\/apa.13038","volume":"104","author":"JW van der Burg","year":"2015","unstructured":"van der Burg JW, Allred EN, Kuban K, O'Shea TM, Dammann O, Leviton A . Maternal obesity and development of the preterm newborn at 2 years. Acta Paediatr 2015;104:900\u2013903.","journal-title":"Acta Paediatr"},{"key":"BFpr201847_CR13","doi-asserted-by":"publisher","first-page":"E124","DOI":"10.1002\/oby.20120","volume":"21","author":"CM Friis","year":"2013","unstructured":"Friis CM, Paasche Roland MC, Godang K et al. Adiposity-related inflammation: effects of pregnancy. Obesity 2013;21:E124\u2013E130.","journal-title":"Obesity"},{"key":"BFpr201847_CR14","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1055\/s-0035-1570027","volume":"34","author":"L Myatt","year":"2016","unstructured":"Myatt L, Maloyan A . Obesity and placental function. Semin Reprod Med 2016;34:42\u201349.","journal-title":"Semin Reprod Med"},{"key":"BFpr201847_CR15","doi-asserted-by":"publisher","first-page":"4231","DOI":"10.1210\/jc.2002-020311","volume":"87","author":"JE Ramsay","year":"2002","unstructured":"Ramsay JE, Ferrell WR, Crawford L, Wallace AM, Greer IA, Sattar N . Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways. J Clin Endocrinol Metab 2002;87:4231\u20134237.","journal-title":"J Clin Endocrinol Metab"},{"key":"BFpr201847_CR16","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1038\/sj.ijo.0801670","volume":"25","author":"NJ Sebire","year":"2001","unstructured":"Sebire NJ, Jolly M, Harris JP et al. Maternal obesity and pregnancy outcome: a study of 287,213 pregnancies in London. Int J Obes Relat Metab Disord 2001;25:1175\u20131182.","journal-title":"Int J Obes Relat Metab Disord"},{"key":"BFpr201847_CR17","doi-asserted-by":"crossref","unstructured":"Hadley EE, Discacciati A, Costantine MM et al. Maternal obesity is associated with chorioamnionitis and earlier indicated preterm delivery among expectantly managed women with preterm premature rupture of membranes. J Matern Fetal Neonatal Med 2017: 1\u20138.","DOI":"10.1080\/14767058.2017.1378329"},{"key":"BFpr201847_CR18","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1016\/j.earlhumdev.2013.09.014","volume":"89","author":"JW van der Burg","year":"2013","unstructured":"van der Burg JW, Allred EN, McElrath TF et al. Is maternal obesity associated with sustained inflammation in extremely low gestational age newborns? Early Hum Dev 2013;89:949\u2013955.","journal-title":"Early Hum Dev"},{"key":"BFpr201847_CR19","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.humimm.2015.10.008","volume":"77","author":"I Peluso","year":"2016","unstructured":"Peluso I, Palmery M . The relationship between body weight and inflammation: lesson from anti-TNF-\u03b1 antibody therapy. Hum Immunol 2016;77:47\u201353.","journal-title":"Hum Immunol"},{"key":"BFpr201847_CR20","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.psyneuen.2014.09.031","volume":"51","author":"M Solmi","year":"2015","unstructured":"Solmi M, Veronese N, Favaro A et al. Inflammatory cytokines and anorexia nervosa: A meta-analysis of cross-sectional and longitudinal studies. Psychoneuroendocrinology 2015;51:237\u2013252.","journal-title":"Psychoneuroendocrinology"},{"key":"BFpr201847_CR21","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1203\/01.PDR.0000182592.76702.E8","volume":"58","author":"I Hansen-Pupp","year":"2005","unstructured":"Hansen-Pupp I, Harling S, Berg AC, Cilio C, Hellstr\u00f6m-Westas L, Ley D . Circulating interferon-gamma and white matter brain damage in preterm infants. Pediatr Res 2005;58:946\u2013952.","journal-title":"Pediatr Res"},{"key":"BFpr201847_CR22","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/j.jstrokecerebrovasdis.2015.12.011","volume":"25","author":"H Lu","year":"2016","unstructured":"Lu H, Wang Q, Lu J, Zhang Q, Kumar P . Risk factors for intraventricular hemorrhage in preterm infants born at 34 weeks of gestation or less following preterm premature rupture of membranes. J Stroke Cerebrovasc Dis 2016;25:807\u2013812.","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"BFpr201847_CR23","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1001\/jamapediatrics.2013.4248","volume":"168","author":"A Pappas","year":"2014","unstructured":"Pappas A, Kendrick DE, Shankaran S et al. Chorioamnionitis and early childhood outcomes among extremely low-gestational-age neonates. JAMA Pediatr 2014;168:137\u2013147.","journal-title":"JAMA Pediatr"},{"key":"BFpr201847_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1203\/00006450-199707000-00001","volume":"42","author":"O Dammann","year":"1997","unstructured":"Dammann O, Leviton A . Maternal intrauterine infection, cytokines, and brain damage in the preterm newborn. Pediatr Res 1997;42:1\u20138.","journal-title":"Pediatr Res"},{"key":"BFpr201847_CR25","doi-asserted-by":"publisher","first-page":"F501","DOI":"10.1136\/fn.88.6.F501","volume":"88","author":"A Heep","year":"2003","unstructured":"Heep A, Behrendt D, Nitsch P, Fimmers R, Bartmann P, Dembinski J . Increased serum levels of interleukin 6 are associated with severe intraventricular haemorrhage in extremely premature infants. Arch Dis Child Fetal Neonatal Ed 2003;88:F501\u2013F504.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFpr201847_CR26","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1007\/s00381-016-3217-9","volume":"32","author":"D Szpecht","year":"2016","unstructured":"Szpecht D, Wiak K, Braszak A, Szymankiewicz M, Gadzinowski J . Role of selected cytokines in the etiopathogenesis of intraventricular hemorrhage in preterm newborns. Childs Nerv Syst 2016;32:2097\u20132103.","journal-title":"Childs Nerv Syst"},{"key":"BFpr201847_CR27","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1203\/01.pdr.0000127015.60185.8a","volume":"55","author":"RM Viscardi","year":"2004","unstructured":"Viscardi RM, Muhumuza CK, Rodriguez A et al. Inflammatory markers in intrauterine and fetal blood and cerebrospinal fluid compartments are associated with adverse pulmonary and neurologic outcomes in preterm infants. Pediatr Res 2004;55:1009\u20131017.","journal-title":"Pediatr Res"},{"key":"BFpr201847_CR28","unstructured":"CPQCC Manual of Definitions for Infants Born in 2016. Available at \n                    https:\/\/www.cpqcc.org\/perinatal-programs\/cpqcc-data-center\/downloads\n                    \n                  . Accessed 15 January 2017. (cited 2 July 2017)."},{"key":"BFpr201847_CR29","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","volume":"92","author":"LA Papile","year":"1978","unstructured":"Papile LA, Burstein J, Burstein R, Koffler H . Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr 1978;92:529\u2013534.","journal-title":"J Pediatr"},{"key":"BFpr201847_CR30","unstructured":"2006 World Health Organization BMI Classification. World Health Organization BMI Classification. Available at \n                    http:\/\/apps.who.int\/bmi\/index.jsp?introPage=intro_3.html\n                    \n                  . Accessed 1 December 2017. (cited 8 February 2018)."},{"key":"BFpr201847_CR31","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1093\/aje\/kwh090","volume":"159","author":"G Zou","year":"2004","unstructured":"Zou G . A modified poisson regression approach to prospective studies with binary data. Am J Epidemiol 2004;159:702\u2013706.","journal-title":"Am J Epidemiol"},{"key":"BFpr201847_CR32","doi-asserted-by":"publisher","first-page":"e141","DOI":"10.1016\/j.ajog.2006.09.014","volume":"196","author":"AA Fanaroff","year":"2007","unstructured":"Fanaroff AA, Stoll BJ, Wright LL et al. Trends in neonatal morbidity and mortality for very low birthweight infants. Am J Obstet Gynecol 2007;196:e141\u2013e148.","journal-title":"Am J Obstet Gynecol"},{"key":"BFpr201847_CR33","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1542\/peds.2009-2959","volume":"126","author":"BJ Stoll","year":"2010","unstructured":"Stoll BJ, Hansen NI, Bell EF et al. Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network. Pediatrics 2010;126:443\u2013456.","journal-title":"Pediatrics"},{"key":"BFpr201847_CR34","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1111\/ppe.12125","volume":"28","author":"GM Shaw","year":"2014","unstructured":"Shaw GM, Wise PH, Mayo J et al. Maternal prepregnancy body mass index and risk of spontaneous preterm birth. Paediatr Perinat Epidemiol 2014;28:302\u2013311.","journal-title":"Paediatr Perinat Epidemiol"},{"key":"BFpr201847_CR35","doi-asserted-by":"publisher","first-page":"2362","DOI":"10.1001\/jama.2013.6295","volume":"309","author":"S Cnattingius","year":"2013","unstructured":"Cnattingius S, Villamor E, Johansson S et al. Maternal obesity and risk of preterm delivery. JAMA 2013;309:2362\u20132370.","journal-title":"JAMA"},{"key":"BFpr201847_CR36","doi-asserted-by":"publisher","first-page":"e211","DOI":"10.1016\/j.ajog.2012.06.002","volume":"207","author":"A Khatibi","year":"2012","unstructured":"Khatibi A, Brantsaeter AL, Sengpiel V et al. Prepregnancy maternal body mass index and preterm delivery. Am J Obstet Gynecol 2012;207:e211\u2013e217.","journal-title":"Am J Obstet Gynecol"},{"key":"BFpr201847_CR37","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1136\/eb-2013-101477","volume":"19","author":"C Gyamf I-Bannerman","year":"2014","unstructured":"Gyamf I-Bannerman C . Maternal obesity is an independent risk factor for spontaneous extremely preterm delivery. Evid Based Med 2014;19:71.","journal-title":"Evid Based Med"},{"key":"BFpr201847_CR38","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/j.1365-3016.2007.00762.x","volume":"21","author":"EA Nohr","year":"2007","unstructured":"Nohr EA, Bech BH, Vaeth M, Rasmussen KM, Henriksen TB, Olsen J . Obesity, gestational weight gain and preterm birth: a study within the Danish National Birth Cohort. Paediatr Perinat Epidemiol 2007;21:5\u201314.","journal-title":"Paediatr Perinat Epidemiol"},{"key":"BFpr201847_CR39","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1007\/s00247-007-0605-z","volume":"37","author":"K Kuban","year":"2007","unstructured":"Kuban K, Adler I, Allred EN et al. Observer variability assessing US scans of the preterm brain: the ELGAN study. Pediatr Radiol 2007;37:1201\u20131208.","journal-title":"Pediatr Radiol"},{"key":"BFpr201847_CR40","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1111\/j.1365-3016.1988.tb00179.x","volume":"2","author":"J Pinto","year":"1988","unstructured":"Pinto J, Paneth N, Kazam E et al. Interobserver variability in neonatal cranial ultrasonography. Paediatr Perinat Epidemiol 1988;2:43\u201358.","journal-title":"Paediatr Perinat Epidemiol"},{"key":"BFpr201847_CR41","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1111\/obr.12486","volume":"18","author":"I Headen","year":"2017","unstructured":"Headen I, Cohen AK, Mujahid M, Abrams B . The accuracy of self-reported pregnancy-related weight: a systematic review. Obes Rev 2017;18:350\u2013369.","journal-title":"Obes Rev"},{"key":"BFpr201847_CR42","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/1742-5573-1-4","volume":"1","author":"JS Kaufman","year":"2004","unstructured":"Kaufman JS, Maclehose RF, Kaufman S . A further critique of the analytic strategy of adjusting for covariates to identify biologic mediation. Epidemiol Perspect Innov 2004;1:4.","journal-title":"Epidemiol Perspect Innov"}],"container-title":["Pediatric Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/pr201847.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/pr201847","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/pr.2018.47","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/pr201847.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T21:05:19Z","timestamp":1684616719000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/pr201847"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,9]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["BFpr201847"],"URL":"https:\/\/doi.org\/10.1038\/pr.2018.47","relation":{},"ISSN":["0031-3998","1530-0447"],"issn-type":[{"value":"0031-3998","type":"print"},{"value":"1530-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,9]]},"assertion":[{"value":"6 September 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 May 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}