{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:06:50Z","timestamp":1782940010688,"version":"3.54.5"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T00:00:00Z","timestamp":1566950400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T00:00:00Z","timestamp":1566950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Obes"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1038\/s41366-019-0443-8","type":"journal-article","created":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T11:03:18Z","timestamp":1566990198000},"page":"559-567","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Bidirectional 10-year associations of accelerometer-measured sedentary behavior and activity categories with weight among middle-aged adults"],"prefix":"10.1038","volume":"44","author":[{"given":"Bethany","family":"Barone Gibbs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Aaby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juned","family":"Siddique","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared P.","family":"Reis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Sternfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara","family":"Whitaker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelley","family":"Pettee Gabriel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,8,28]]},"reference":[{"key":"443_CR1","unstructured":"NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet. 2017;390:2627\u201342. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5735219\/ ."},{"key":"443_CR2","doi-asserted-by":"publisher","first-page":"e1077","DOI":"10.1016\/S2214-109X(18)30357-7","volume":"6","author":"R Guthold","year":"2018","unstructured":"Guthold R, Stevens GA, Riley LM, Bull FC. Worldwide trends in insufficient physical activity from 2001 to 2016: a pooled analysis of 358 population-based surveys with 1.9 million participants. The Lancet Global Health. 2018;6:e1077\u201386.","journal-title":"The Lancet Global Health"},{"key":"443_CR3","unstructured":"World Health Organization (WHO). Global action plan on physical activity 2018\u20132030: more active people for a healthier world. Geneva: World Health Organization; 2018."},{"key":"443_CR4","unstructured":"World Health Organization. Global status report on noncommunicable diseases. World Health Organization, Geneva, Switzerland, 2014."},{"key":"443_CR5","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.pcad.2013.09.012","volume":"56","author":"DL Swift","year":"2014","unstructured":"Swift DL, Johannsen NM, Lavie CJ, Earnest CP, Church TS. The role of exercise and physical activity in weight loss and maintenance. Prog Cardiovasc Dis. 2014;56:441\u20137.","journal-title":"Prog Cardiovasc Dis"},{"key":"443_CR6","doi-asserted-by":"publisher","first-page":"1769","DOI":"10.1038\/ijo.2017.186","volume":"41","author":"U Ekelund","year":"2017","unstructured":"Ekelund U, Kolle E, Steene-Johannessen J, Dalene KE, Nilsen AKO, Anderssen SA. et al. Objectively measured sedentary time and physical activity and associations with body weight gain: does body weight determine a decline in moderate and vigorous intensity physical activity?. Int J Obes (2005). 2017;41:1769\u201374.","journal-title":"Int J Obes (2005)"},{"key":"443_CR7","doi-asserted-by":"publisher","first-page":"1897","DOI":"10.1007\/s40279-016-0518-9","volume":"46","author":"K Beaulieu","year":"2016","unstructured":"Beaulieu K, Hopkins M, Blundell J, Finlayson G. Does habitual physical activity increase the sensitivity of the appetite control system? a systematic review. Sports Med. 2016;46:1897\u2013919.","journal-title":"Sports Med"},{"key":"443_CR8","volume-title":"2018 Physical Activity Guidelines Advisory Committee Scientific Report","author":"2018 Physical Activity Guidelines Advisory Committee.","year":"2018","unstructured":"2018 Physical Activity Guidelines Advisory Committee. 2018 Physical Activity Guidelines Advisory Committee Scientific Report. Washington D.C.: U.S. Department of Health and Human Services; 2018."},{"key":"443_CR9","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1007\/s40279-017-0828-6","volume":"48","author":"SDI Campbell","year":"2018","unstructured":"Campbell SDI, Brosnan BJ, Chu AKY, Skeaff CM, Rehrer NJ, Perry TL, et al. Sedentary behavior and body weight and composition in adults: a systematic review and meta-analysis of prospective studies. Sports Med. 2018;48:585\u201395.","journal-title":"Sports Med"},{"key":"443_CR10","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1093\/ajcn\/88.3.612","volume":"88","author":"U Ekelund","year":"2008","unstructured":"Ekelund U, Brage S, Besson H, Sharp S, Wareham NJ. Time spent being sedentary and weight gain in healthy adults: reverse or bidirectional causality? Am J Clin Nutr. 2008;88:612\u20137.","journal-title":"Am J Clin Nutr"},{"key":"443_CR11","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1111\/j.1467-842X.2000.tb01579.x","volume":"24","author":"K Ball","year":"2000","unstructured":"Ball K, Crawford D, Owen N. Too fat to exercise? Obesity as a barrier to physical activity. Aust NZ J Public Health. 2000;24:331\u20133.","journal-title":"Aust NZ J Public Health"},{"key":"443_CR12","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1080\/09513590.2016.1269741","volume":"33","author":"JE Blumel","year":"2017","unstructured":"Blumel JE, Arteaga E, Mezones-Holguin E, Zuniga MC, Witis S, Vallejo MS, et al. Obesity is associated with a higher prevalence of musculoskeletal pain in middle-aged women. Gynecol Endocrinol. 2017;33:378\u201382.","journal-title":"Gynecol Endocrinol"},{"key":"443_CR13","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1007\/s13679-016-0229-4","volume":"5","author":"J Collins","year":"2016","unstructured":"Collins J, Meng C, Eng A. Psychological impact of severe obesity. Curr Obes Rep. 2016;5:435\u201340.","journal-title":"Curr Obes Rep"},{"key":"443_CR14","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1056\/NEJMoa010492","volume":"345","author":"FB Hu","year":"2001","unstructured":"Hu FB, Manson JE, Stampfer MJ, Colditz G, Liu S, Solomon CG, et al. Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. New Engl J Med. 2001;345:790\u20137.","journal-title":"New Engl J Med"},{"key":"443_CR15","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.genhosppsych.2009.04.002","volume":"31","author":"B Roshanaei-Moghaddam","year":"2009","unstructured":"Roshanaei-Moghaddam B, Katon WJ, Russo J. The longitudinal effects of depression on physical activity. Gen Hosp Psychiatry. 2009;31:306\u201315.","journal-title":"Gen Hosp Psychiatry"},{"key":"443_CR16","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-017-4255-2","volume":"17","author":"J Choi","year":"2017","unstructured":"Choi J, Lee M, Lee JK, Kang D, Choi JY. Correlates associated with participation in physical activity among adults: a systematic review of reviews and update. BMC Public Health. 2017;17:356.","journal-title":"BMC Public Health"},{"key":"443_CR17","doi-asserted-by":"publisher","first-page":"773","DOI":"10.3390\/ijerph110100773","volume":"11","author":"SF Chastin","year":"2014","unstructured":"Chastin SF, Fitzpatrick N, Andrews M, DiCroce N. Determinants of sedentary behavior, motivation, barriers and strategies to reduce sitting time in older women: a qualitative investigation. Int J Environ Res Public Health. 2014;11:773\u201391.","journal-title":"Int J Environ Res Public Health"},{"key":"443_CR18","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1016\/j.amepre.2017.07.009","volume":"53","author":"B Barone Gibbs","year":"2017","unstructured":"Barone Gibbs B, Pettee Gabriel K, Carnethon MR, Gary-Webb T, Jakicic JM, Rana JS, et al. Sedentary time, physical activity, and adiposity: cross-sectional and longitudinal associations in CARDIA. Am J Prev Med. 2017;53:764\u201371.","journal-title":"Am J Prev Med"},{"key":"443_CR19","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1038\/oby.2006.166","volume":"14","author":"LH Mortensen","year":"2006","unstructured":"Mortensen LH, Siegler IC, Barefoot JC, Gronbaek M, Sorensen TI. Prospective associations between sedentary lifestyle and BMI in midlife. Obesity (Silver Spring, Md.). 2006;14:1462\u201371.","journal-title":"Obesity (Silver Spring, Md.)"},{"key":"443_CR20","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1038\/sj.ijo.0802548","volume":"28","author":"L Petersen","year":"2004","unstructured":"Petersen L, Schnohr P, Sorensen TI. Longitudinal study of the long-term relation between physical activity and obesity in adults. Int J Obes Relat Metab Disord. 2004;28:105\u201312.","journal-title":"Int J Obes Relat Metab Disord"},{"key":"443_CR21","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1038\/ijo.2014.66","volume":"39","author":"R Golubic","year":"2015","unstructured":"Golubic R, Wijndaele K, Sharp SJ, Simmons RK, Griffin SJ, Wareham NJ, et al. Physical activity, sedentary time and gain in overall and central body fat: 7-year follow-up of the ProActive trial cohort. Int J Obesity (2005). 2015;39:142\u20138.","journal-title":"Int J Obesity (2005)"},{"key":"443_CR22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001618","volume":"11","author":"RC Richmond","year":"2014","unstructured":"Richmond RC, Smith GD, Ness AR, den Hoed M, McMahon G, Timpson NJ. Assessing causality in the association between child adiposity and physical activity levels: a Mendelian randomization analysis. PLoS Med. 2014;11:e1001618.","journal-title":"PLoS Med"},{"key":"443_CR23","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1016\/0895-4356(88)90080-7","volume":"41","author":"GD Friedman","year":"1988","unstructured":"Friedman GD, Cutter GR, Donahue RP, Hughes GH, Hulley SB, Jacobs DR Jr., et al. CARDIA: study design, recruitment, and some characteristics of the examined subjects. J Clin Epidemiol. 1988;41:1105\u201316.","journal-title":"J Clin Epidemiol"},{"key":"443_CR24","doi-asserted-by":"publisher","first-page":"2145","DOI":"10.1093\/aje\/kwy117","volume":"187","author":"K Pettee Gabriel","year":"2018","unstructured":"Pettee Gabriel K, Sidney S, Jacobs DR Jr., Whitaker KM, Carnethon MR, Lewis CE, et al. Ten-year changes in accelerometer-based physical activity and sedentary time during midlife: the CARDIA Study. Am J Epidemiol. 2018;187:2145\u201350.","journal-title":"Am J Epidemiol"},{"key":"443_CR25","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1249\/MSS.0000000000001568","volume":"50","author":"KM Whitaker","year":"2018","unstructured":"Whitaker KM, Pettee Gabriel K, Jacobs DR Jr., Sidney S, Sternfeld B. Comparison of two generations of actigraph accelerometers: the CARDIA study. Med Sci Sports Exerc. 2018;50:1333\u201340.","journal-title":"Med Sci Sports Exerc"},{"key":"443_CR26","doi-asserted-by":"publisher","unstructured":"Tudor-Locke C, Camhi SM, Troiano RP. A catalog of rules, variables, and definitions applied to accelerometer data in the National Health and Nutrition Examination Survey, 2003\u20132006. Prev Chronic Dis. 2012;9:110332. https:\/\/doi.org\/10.5888\/pcd9.110332 , https:\/\/www.cdc.gov\/pcd\/issues\/2012\/11_0332.htm .","DOI":"10.5888\/pcd9.110332"},{"key":"443_CR27","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1249\/mss.0b013e31815a51b3","volume":"40","author":"RP Troiano","year":"2008","unstructured":"Troiano RP, Berrigan D, Dodd KW, Masse LC, Tilert T, McDowell M. Physical activity in the United States measured by accelerometer. Med Sci Sports Exerc. 2008;40:181\u20138.","journal-title":"Med Sci Sports Exerc"},{"issue":"11 Suppl","key":"443_CR28","doi-asserted-by":"publisher","first-page":"S544","DOI":"10.1249\/01.mss.0000185674.09066.8a","volume":"37","author":"LC Masse","year":"2005","unstructured":"Masse LC, Fuemmeler BF, Anderson CB, Matthews CE, Trost SG, Catellier DJ, et al. Accelerometer data reduction: a comparison of four reduction algorithms on select outcome variables. Med Sci Sports Exerc. 2005;37(11 Suppl):S544\u201354.","journal-title":"Med Sci Sports Exerc"},{"issue":"1Suppl 1","key":"443_CR29","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1249\/MSS.0b013e3182399b7e","volume":"44","author":"P Freedson","year":"2012","unstructured":"Freedson P, Bowles HR, Troiano R, Haskell W. Assessment of physical activity using wearable monitors: recommendations for monitor calibration and use in the field. Med Sci Sports Exerc. 2012;44(1Suppl 1):S1\u20134.","journal-title":"Med Sci Sports Exerc"},{"key":"443_CR30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0118078","volume":"10","author":"Y Kim","year":"2015","unstructured":"Kim Y, Welk GJ, Braun SI, Kang M. Extracting objective estimates of sedentary behavior from accelerometer data: measurement considerations for surveillance and research applications. PLoS ONE. 2015;10:e0118078.","journal-title":"PLoS ONE"},{"key":"443_CR31","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/j.diabres.2012.05.020","volume":"97","author":"DW Dunstan","year":"2012","unstructured":"Dunstan DW, Howard B, Healy GN, Owen N. Too much sitting-a health hazard. Diabetes Res Clin Pract. 2012;97:368\u201376.","journal-title":"Diabetes Res Clin Pract"},{"key":"443_CR32","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1139\/h2012-024","volume":"37","author":"Sedentary Behavior Research Network.","year":"2012","unstructured":"Sedentary Behavior Research Network. Letter to the editor: standardized use of the terms \u201csedentary\u201d and \u201csedentary behaviours\u201d. Appl Physiol Nutr Metab. 2012;37:540\u20132.","journal-title":"Appl Physiol Nutr Metab"},{"key":"443_CR33","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1016\/S0002-8223(21)01299-2","volume":"91","author":"A Mcdonald","year":"1991","unstructured":"Mcdonald A, Vanhorn L, Slattery M, Hilner J, Bragg C, Caan B, et al. The Cardia dietary history - development, implementation, and evaluation. J Am Diet Assoc. 1991;91:1104\u201312.","journal-title":"J Am Diet Assoc"},{"key":"443_CR34","doi-asserted-by":"publisher","first-page":"e119","DOI":"10.1111\/j.1467-789X.2010.00775.x","volume":"12","author":"DC Wilks","year":"2011","unstructured":"Wilks DC, Besson H, Lindroos AK, Ekelund U. Objectively measured physical activity and obesity prevention in children, adolescents and adults: a systematic review of prospective studies. Obes Rev. 2011;12:e119\u201329.","journal-title":"Obes Rev"},{"key":"443_CR35","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1038\/sj.ijo.0802525","volume":"28","author":"H Bak","year":"2003","unstructured":"Bak H, Petersen L, S\u00f8rensen TIA. Physical activity in relation to development and maintenance of obesity in men with and without juvenile onset obesity. Int J Obesity. 2003;28:99.","journal-title":"Int J Obesity"},{"key":"443_CR36","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1097\/EDE.0000000000000228","volume":"26","author":"S Stenholm","year":"2015","unstructured":"Stenholm S, Vahtera J, Kawachi I, Pentti J, Halonen JI, Westerlund H, et al. Patterns of weight gain in middle-aged and older US adults, 1992\u20132010. Epidemiology (Cambridge, Mass.). 2015;26:165\u20138.","journal-title":"Epidemiology (Cambridge, Mass.)"},{"key":"443_CR37","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.ypmed.2017.05.030","volume":"101","author":"VR Varma","year":"2017","unstructured":"Varma VR, Dey D, Leroux A, Di J, Urbanek J, Xiao L, et al. Re-evaluating the effect of age on physical activity over the lifespan. Prev Med. 2017;101:102\u20138.","journal-title":"Prev Med"},{"key":"443_CR38","doi-asserted-by":"publisher","first-page":"E64","DOI":"10.5888\/pcd10.120308","volume":"10","author":"JJ Ashman","year":"2013","unstructured":"Ashman JJ, Beresovsky V. Multiple chronic conditions among US adults who visited physician offices: data from the National Ambulatory Medical Care Survey, 2009. Prev Chronic Dis. 2013;10:E64.","journal-title":"Prev Chronic Dis"},{"key":"443_CR39","doi-asserted-by":"publisher","DOI":"10.1186\/s12966-017-0525-8","volume":"14","author":"MS Tremblay","year":"2017","unstructured":"Tremblay MS, Aubert S, Barnes JD, Saunders TJ, Carson V, Latimer-Cheung AE, et al. Sedentary Behavior Research Network (SBRN)- Terminology Consensus Project process and outcome. Int J Behav Nutr Phys Act. 2017;14:75.","journal-title":"Int J Behav Nutr Phys Act"}],"container-title":["International Journal of Obesity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/s41366-019-0443-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41366-019-0443-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41366-019-0443-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T21:16:21Z","timestamp":1684617381000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41366-019-0443-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,28]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["443"],"URL":"https:\/\/doi.org\/10.1038\/s41366-019-0443-8","relation":{},"ISSN":["0307-0565","1476-5497"],"issn-type":[{"value":"0307-0565","type":"print"},{"value":"1476-5497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,28]]},"assertion":[{"value":"15 February 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Dr. Barone Gibbs discloses grant funding from the American Heart Association, the National Institutes of Health, and the Tomayko Fund. Drs. Juned Siddique and Kelley Pettee Gabriel disclose grant funding from the National Institutes of Health. Mr. David Aaby, Dr. Barbara Sternfeld, Dr. Kara Whitaker declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}