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We assessed a range of adiposity indices to determine whether they offer more accurate predictions of RSF than BMI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Renal sinus fat (RSF) and RSF relative to total kidney area (RSF%) were assessed via MRI in 74 individuals with severe obesity and 47 lean volunteers. 50 persons with obesity were re-evaluated 6 to 12 months after undergoing bariatric surgery. In multivariable regression analyses adjusted for age, sex, and BMI, the Body Roundness Index (BRI), waist-to-height ratio (WHtR), and waist circumference showed the strongest associations with RSF. Of these, only WHtR was significantly associated with RSF%. In univariate analyses, both RSF and RSF% were inversely correlated with estimated glomerular filtration rate (eGFR); however, in multivariate analysis, only RSF% remained independently associated with eGFR. Post-bariatric surgery, RSF change correlated with changes in WHtR and BRI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Adiposity measures incorporating waist circumference are associated with RSF independent of BMI. While RSF exhibits a stronger relationship with adiposity measures, RSF% predicts eGFR. Both metrics offer complementary insights and should be considered in future studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1038\/s41366-025-01974-4","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T04:03:50Z","timestamp":1765598630000},"page":"586-591","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Waist-to-height ratio as a non-invasive marker of renal sinus fat: a MRI-based cohort study"],"prefix":"10.1038","volume":"50","author":[{"given":"Diego","family":"Moriconi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miikka-Juhani","family":"Honka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina","family":"Saukko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilia","family":"Moritz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aino","family":"Latva-Rasku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5063-304X","authenticated-orcid":false,"given":"Prince","family":"Dadson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9004-4200","authenticated-orcid":false,"given":"Nelli","family":"Tuomola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Pekkarinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6435-9264","authenticated-orcid":false,"given":"Paulina","family":"Salminen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9597-338X","authenticated-orcid":false,"given":"Pirjo","family":"Nuutila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3050-8692","authenticated-orcid":false,"given":"Eleni","family":"Rebelos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,13]]},"reference":[{"key":"1974_CR1","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/s41569-023-00847-5","volume":"20","author":"PL Valenzuela","year":"2023","unstructured":"Valenzuela PL, Carrera-Bastos P, Castillo-Garc\u00eda A, Lieberman DE, Santos-Lozano A, Lucia A. 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