{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T12:38:41Z","timestamp":1794573521079,"version":"4.9.1"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T00:00:00Z","timestamp":1613606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T00:00:00Z","timestamp":1613606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Expo Sci Environ Epidemiol"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1038\/s41370-021-00292-x","type":"journal-article","created":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T10:05:28Z","timestamp":1613815528000},"page":"461-471","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Environmental metal exposures and kidney function of Guatemalan sugarcane workers"],"prefix":"10.1038","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1325-6246","authenticated-orcid":false,"given":"Jaime","family":"Butler-Dawson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine A.","family":"James","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyndsay","family":"Krisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Jaramillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miranda","family":"Dally","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Pilloni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Asensio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Adgate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee S.","family":"Newman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,2,18]]},"reference":[{"key":"292_CR1","doi-asserted-by":"publisher","first-page":"1843","DOI":"10.1056\/NEJMra1813869","volume":"380","author":"RJ Johnson","year":"2019","unstructured":"Johnson RJ, Wesseling C, Newman LS. Chronic kidney disease of unknown cause in agricultural communities. N Engl J Med. 2019;380:1843\u201352.","journal-title":"N Engl J Med"},{"key":"292_CR2","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1476-069X-14-6","volume":"14","author":"C Jayasumana","year":"2015","unstructured":"Jayasumana C, Paranagama P, Agampodi S, Wijewardane C, Gunatilake S, Siribaddana S. Drinking well water and occupational exposure to Herbicides is associated with chronic kidney disease, in Padavi-Sripura, Sri Lanka. Environ Health. 2015;14:6.","journal-title":"Environ Health"},{"key":"292_CR3","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1053\/j.ajkd.2013.08.014","volume":"63","author":"C Wesseling","year":"2014","unstructured":"Wesseling C, Crowe J, Hogstedt C, Jakobsson K, Lucas R, Wegman DH, et al. Resolving the enigma of the Mesoamerican nephropathy: a research workshop summary. Am J Kidney Dis. 2014;63:396\u2013404.","journal-title":"Am J Kidney Dis"},{"key":"292_CR4","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1093\/ckj\/sfx062","volume":"10","author":"BA Vervaet","year":"2017","unstructured":"Vervaet BA, D\u2019Haese PC, Verhulst A. Environmental toxin-induced acute kidney injury. Clin Kidney J. 2017;10:747\u201358.","journal-title":"Clin Kidney J."},{"key":"292_CR5","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1289\/ehp.9310057","volume":"100","author":"BA Fowler","year":"1993","unstructured":"Fowler BA. Mechanisms of kidney cell injury from metals. Environ Health Perspect. 1993;100:57\u201363.","journal-title":"Environ Health Perspect"},{"key":"292_CR6","first-page":"133","volume":"2012","author":"PB Tchounwou","year":"2012","unstructured":"Tchounwou PB, Yedjou CG, Patlolla AK, Sutton DJ. Heavy metal toxicity and the environment. Exp Suppl. 2012;2012:133\u201364.","journal-title":"Exp Suppl"},{"key":"292_CR7","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1136\/oemed-2018-105427","volume":"76","author":"N Pearce","year":"2019","unstructured":"Pearce N, Caplin B. Let\u2019s take the heat out of the CKDu debate: more evidence is needed. Occup Environ Med. 2019;76:357\u20139.","journal-title":"Occup Environ Med"},{"key":"292_CR8","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1016\/j.scitotenv.2015.02.097","volume":"518","author":"T Rango","year":"2015","unstructured":"Rango T, Jeuland M, Manthrithilake H, McCornick P. Nephrotoxic contaminants in drinking water and urine, and chronic kidney disease in rural Sri Lanka. Sci Total Environ. 2015;518:574\u201385.","journal-title":"Sci Total Environ"},{"key":"292_CR9","doi-asserted-by":"publisher","first-page":"2125","DOI":"10.3390\/ijerph110202125","volume":"11","author":"C Jayasumana","year":"2014","unstructured":"Jayasumana C, Gunatilake S, Senanayake P. Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in Sri Lanka? Int J Environ Res Public Health. 2014;11:2125\u201347.","journal-title":"Int J Environ Res Public Health"},{"key":"292_CR10","doi-asserted-by":"publisher","first-page":"2329","DOI":"10.1007\/s10653-019-00264-z","volume":"41","author":"M Kulathunga","year":"2019","unstructured":"Kulathunga M, Wijayawardena MAA, Naidu R, Wijeratne AW. Chronic kidney disease of unknown aetiology in Sri Lanka and the exposure to environmental chemicals: a review of literature. Environ Geochem Health. 2019;41:2329\u201338.","journal-title":"Environ Geochem Health"},{"key":"292_CR11","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s10653-007-9129-6","volume":"30","author":"JMRS Bandara","year":"2008","unstructured":"Bandara JMRS, Senevirathna DMAN, Dasanayake DMRSB, Herath V, Bandara JMRP, Abeysekara T, et al. Chronic renal failure among farm families in cascade irrigation systems in Sri Lanka associated with elevated dietary cadmium levels in rice and freshwater fish (Tilapia). Environ Geochem Health. 2008;30:465\u201378.","journal-title":"Environ Geochem Health"},{"key":"292_CR12","doi-asserted-by":"publisher","first-page":"212","DOI":"10.2166\/wh.2018.070","volume":"16","author":"HMAS Herath","year":"2018","unstructured":"Herath HMAS, Kawakami T, Nagasawa S, Serikawa Y, Motoyama A, Chaminda GGT, et al. Arsenic, cadmium, lead, and chromium in well water, rice, and human urine in Sri Lanka in relation to chronic kidney disease of unknown etiology. J Water Health. 2018;16:212\u201322.","journal-title":"J Water Health"},{"key":"292_CR13","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1186\/s12882-015-0109-2","volume":"16","author":"C Jayasumana","year":"2015","unstructured":"Jayasumana C, Gunatilake S, Siribaddana S. Simultaneous exposure to multiple heavy metals and glyphosate may contribute to Sri Lankan agricultural nephropathy. BMC Nephrol. 2015;16:103.","journal-title":"BMC Nephrol"},{"key":"292_CR14","doi-asserted-by":"publisher","first-page":"555","DOI":"10.20937\/RICA.2018.34.04.01","volume":"34","author":"LP Bustamante-Montes","year":"2018","unstructured":"Bustamante-Montes LP, Flores-Polanco JA, Isaac-Olive K, Hernandez-Tellez M, Campuzano-Gonzalez ME, Ramirez-Duran N. Exploratory study on the association of heavy metals and the nephropathy of unknown etiology in the western state of mexico. Rev Internacional De Contaminacion Ambiental. 2018;34:555\u201364.","journal-title":"Rev Internacional De Contaminacion Ambiental"},{"key":"292_CR15","unstructured":"McClean M, Laws R, Kaufman JS, Weiner DE, Rodr\u0131guez JMS, Ramirez-Rubio O, et al. Biological sampling report: investigating biomarkers of kidney injury and chronic kidney disease among workers in Western Nicaragua. Boston University; Boston University School of Public Health 715 Albany St - Boston, MA; 2012."},{"key":"292_CR16","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1136\/oemed-2019-105772","volume":"76","author":"ET Smpokou","year":"2019","unstructured":"Smpokou ET, Gonzalez-Quiroz M, Martins C, Alvito P, Le Blond J, Glaser J, et al. Environmental exposures in young adults with declining kidney function in a population at risk of Mesoamerican nephropathy. Occup Environ Med. 2019;76:920\u20136.","journal-title":"Occup Environ Med"},{"key":"292_CR17","doi-asserted-by":"crossref","unstructured":"Fischer RSB, Unrine J, Vangala C, Sanderson WT, Mandayam S, Murray KO. Evidence of nickel and other trace elements and their relationship to clinical findings in acute Mesoamerican nephropathy: a case-control analysis. PLoS ONE. 2020;15(11):e0240988.","DOI":"10.1371\/journal.pone.0240988"},{"key":"292_CR18","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1053\/j.ajkd.2016.10.036","volume":"69","author":"J Wijkstrom","year":"2017","unstructured":"Wijkstrom J, Gonzalez-Quiroz M, Hernandez M, Trujillo Z, Hultenby K, Ring A, et al. Renal morphology, clinical findings, and progression rate in Mesoamerican nephropathy. Am J Kidney Dis. 2017;69:626\u201336.","journal-title":"Am J Kidney Dis"},{"key":"292_CR19","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1097\/JOM.0000000000001284","volume":"60","author":"J Butler-Dawson","year":"2018","unstructured":"Butler-Dawson J, Krisher L, Asensio C, Cruz A, Tenney L, Weitzenkamp D, et al. Risk factors for declines in kidney function in sugarcane workers in Guatemala. J Occup Environ Med. 2018;60:548\u201358.","journal-title":"J Occup Environ Med"},{"key":"292_CR20","doi-asserted-by":"crossref","unstructured":"Butler-Dawson J, Krisher L, Yoder H, Dally M, Sorensen C, Johnson RJ, et al. Evaluation of heat stress and cumulative incidence of acute kidney injury in sugarcane workers in Guatemala. Int Arch Occup Environ Health. 2019;92(7):977\u201390.","DOI":"10.1007\/s00420-019-01426-3"},{"key":"292_CR21","first-page":"111","volume":"19","author":"E Pruszkowski","year":"1998","unstructured":"Pruszkowski E, Neubauer K, Thomas R. An overview of clinical applications by inductively coupled plasma mass spectrometry. At Spectrosc. 1998;19:111\u20135.","journal-title":"At Spectrosc"},{"key":"292_CR22","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/0584-8547(95)01372-5","volume":"51","author":"DE Nixon","year":"1996","unstructured":"Nixon DE, Moyer TP. Routine clinical determination of lead, arsenic, cadmium, and thallium in urine and whole blood by inductively coupled plasma mass spectrometry. Spectrochimica Acta Part B: Atomic Spectroscopy. 1996;51:13\u201325.","journal-title":"Spectrochimica Acta Part B: Atomic Spectroscopy"},{"key":"292_CR23","unstructured":"Jarrett JM, Cadwell KL, Jones RL. Urine multi-element ICP-DRC-MS: antimony, arsenic, barium, beryllium, cadmium, cesium, cobalt, lead, manganese, molybdenum, platinum, strontium, thallium, tin, tungsten, and uranium. CDC-Division of Laboratory Sciences, Laboratory Protocol. Centers for Disease Control and Prevention, Adopted October 01, 1994, updated September 15, 2014."},{"key":"292_CR24","doi-asserted-by":"publisher","first-page":"4647685","DOI":"10.1155\/2016\/4647685","volume":"2016","author":"T Fiseha","year":"2016","unstructured":"Fiseha T, Tamir Z. Urinary markers of tubular injury in early diabetic nephropathy. Int J Nephrol. 2016;2016:4647685.","journal-title":"Int J Nephrol"},{"key":"292_CR25","doi-asserted-by":"publisher","first-page":"265","DOI":"10.2217\/bmm.10.12","volume":"4","author":"P Devarajan","year":"2010","unstructured":"Devarajan P. Neutrophil gelatinase-associated lipocalin: a promising biomarker for human acute kidney injury. Biomark Med. 2010;4:265\u201380.","journal-title":"Biomark Med"},{"key":"292_CR26","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1111\/j.1752-8062.2008.00053.x","volume":"1","author":"VS Vaidya","year":"2008","unstructured":"Vaidya VS, Waikar SS, Ferguson MA, Collings FB, Sunderland K, Gioules C, et al. Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans. Clin Transl Sci. 2008;1:200\u20138.","journal-title":"Clin Transl Sci"},{"key":"292_CR27","doi-asserted-by":"publisher","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","volume":"150","author":"AS Levey","year":"2009","unstructured":"Levey AS, Stevens LA, Schmid CH, Zhang YP, Castro AF, Feldman HI, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150:604\u201312.","journal-title":"Ann Intern Med"},{"key":"292_CR28","doi-asserted-by":"publisher","first-page":"202","DOI":"10.3390\/ijerph110100202","volume":"11","author":"RV Caruso","year":"2013","unstructured":"Caruso RV, O\u2019Connor RJ, Stephens WE, Cummings KM, Fong GT. Toxic metal concentrations in cigarettes obtained from U.S. smokers in 2009: results from the International Tobacco Control (ITC) United States survey cohort. Int J Environ Res Public Health. 2013;11:202\u201317.","journal-title":"Int J Environ Res Public Health"},{"key":"292_CR29","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1080\/1047322X.1990.10389587","volume":"5","author":"R Hornung","year":"1990","unstructured":"Hornung R, Reed L. Estimation of average concentration in the presence of nondetectable values. Appl Occup Environ Hyg. 1990;5:46\u201351.","journal-title":"Appl Occup Environ Hyg"},{"key":"292_CR30","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1289\/ehp.7337","volume":"113","author":"DB Barr","year":"2005","unstructured":"Barr DB, Wilder LC, Caudill SP, Gonzalez AJ, Needham LL, Pirkle JL. Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements. Environ Health Perspect. 2005;113:192\u2013200.","journal-title":"Environ Health Perspect"},{"key":"292_CR31","unstructured":"World Health Organization. Office of Occupational H. Biological monitoring of chemical exposure in the workplace: guidelines. Geneva: World Health Organization;1996."},{"key":"292_CR32","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1136\/oem.2010.056077","volume":"68","author":"VM Weaver","year":"2011","unstructured":"Weaver VM, Kim N-S, Jaar BG, Schwartz BS, Parsons PJ, Steuerwald AJ, et al. Associations of low-level urine cadmium with kidney function in lead workers. Occup Environ Med. 2011;68:250\u20136.","journal-title":"Occup Environ Med"},{"key":"292_CR33","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1289\/ehp.8033","volume":"113","author":"A Akesson","year":"2005","unstructured":"Akesson A, Lundh T, Vahter M, Bjellerup P, Lidfeldt J, Nerbrand C, et al. Tubular and glomerular kidney effects in Swedish women with low environmental cadmium exposure. Environ Health Perspect. 2005;113:1627\u201331.","journal-title":"Environ Health Perspect"},{"key":"292_CR34","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1053\/ajkd.2001.28589","volume":"38","author":"L Hellstrom","year":"2001","unstructured":"Hellstrom L, Elinder CG, Dahlberg B, Lundberg M, Jarup L, Persson B, et al. Cadmium exposure and end-stage renal disease. Am J Kidney Dis. 2001;38:1001\u20138.","journal-title":"Am J Kidney Dis"},{"key":"292_CR35","first-page":"425","volume":"38","author":"RG Adams","year":"1969","unstructured":"Adams RG, Harrison JF, Scott P. The development of cadmium-induced proteinuria, impaired renal function, and osteomalacia in alkaline battery workers. Q J Med. 1969;38:425\u201343.","journal-title":"Q J Med"},{"key":"292_CR36","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1016\/j.tiv.2009.07.020","volume":"23","author":"LG Navarro-Moreno","year":"2009","unstructured":"Navarro-Moreno LG, Quintanar-Escorza MF, Gonzalez S, Mondragon R, Cerbon-Solorzano J, Valdes J, et al. Effects of lead intoxication on intercellular junctions and biochemical alterations of the renal proximal tubule cells. Toxicol Vitro. 2009;23:1298\u2013304.","journal-title":"Toxicol Vitro"},{"key":"292_CR37","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1001\/archinte.1978.03630330067019","volume":"138","author":"RE Gerhardt","year":"1978","unstructured":"Gerhardt RE, Hudson JB, Raghunatha RN, Sobel RE. Chronic renal insufficiency from cortical necrosis induced by arsenic poisoning. Arch Intern Med. 1978;138:1267\u20139.","journal-title":"Arch Intern Med"},{"key":"292_CR38","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1136\/oemed-2012-100887","volume":"70","author":"R Hambach","year":"2013","unstructured":"Hambach R, Lison D, D\u2019Haese P, Weyler J, Francois G, De Schryver A, et al. Adverse effects of low occupational cadmium exposure on renal and oxidative stress biomarkers in solderers. Occup Environ Med. 2013;70:108\u201313.","journal-title":"Occup Environ Med"},{"key":"292_CR39","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1053\/j.ajkd.2012.09.011","volume":"61","author":"LY Zheng","year":"2013","unstructured":"Zheng LY, Umans JG, Tellez-Plaza M, Yeh F, Francesconi KA, Goessler W, et al. Urine arsenic and prevalent albuminuria: evidence from a population-based study. Am J Kidney Dis. 2013;61:385\u201394.","journal-title":"Am J Kidney Dis"},{"key":"292_CR40","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1097\/JOM.0000000000001529","volume":"61","author":"CJ Sorensen","year":"2019","unstructured":"Sorensen CJ, Butler-Dawson J, Dally M, Krisher L, Griffin BR, Johnson RJ, et al. Risk factors and mechanisms underlying cross-shift decline in kidney function in Guatemalan sugarcane workers. J Occup Environ Med. 2019;61:239\u201350.","journal-title":"J Occup Environ Med"},{"key":"292_CR41","doi-asserted-by":"publisher","first-page":"337","DOI":"10.2215\/CJN.03530708","volume":"4","author":"D Bolignano","year":"2009","unstructured":"Bolignano D, Lacquaniti A, Coppolino G, Donato V, Campo S, Fazio MR, et al. Neutrophil gelatinase-associated lipocalin (NGAL) and progression of chronic kidney disease. Clin J Am Soc Nephrol. 2009;4:337\u201344.","journal-title":"Clin J Am Soc Nephrol"},{"key":"292_CR42","doi-asserted-by":"publisher","DOI":"10.1038\/srep18048","volume":"5","author":"KJ Chuang","year":"2015","unstructured":"Chuang KJ, Pan CH, Su CL, Lai CH, Lin WY, Ma CM, et al. Urinary neutrophil gelatinase-associated lipocalin is associated with heavy metal exposure in welding workers. Sci Rep. 2015;5:18048.","journal-title":"Sci Rep"},{"key":"292_CR43","unstructured":"Nordberg GF, Fowler BA, Nordberg M. Handbook on the toxicology of metals. 3rd ed. Academic Press; Academic Press\/Elsevier, USA; 2007."},{"key":"292_CR44","unstructured":"CDC. Fourth report on human exposure to environmental chemicals, updated tables, (January 2019). Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention; 2019."},{"key":"292_CR45","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1159\/000381239","volume":"66","author":"C Roncal-Jimenez","year":"2015","unstructured":"Roncal-Jimenez C, Lanaspa MA, Jensen T, Sanchez-Lozada LG, Johnson RJ. Mechanisms by which dehydration may lead to chronic kidney disease. Ann Nutr Metab. 2015;66:10\u20133.","journal-title":"Ann Nutr Metab"},{"key":"292_CR46","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1053\/j.ajkd.2013.10.062","volume":"63","author":"R Correa-Rotter","year":"2014","unstructured":"Correa-Rotter R, Wesseling C, Johnson RJ. CKD of unknown origin in Central America: the case for a Mesoamerican nephropathy. Am J Kidney Dis. 2014;63:506\u201320.","journal-title":"Am J Kidney Dis"},{"key":"292_CR47","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/j.toxlet.2012.02.005","volume":"210","author":"A Chaumont","year":"2012","unstructured":"Chaumont A, Nickmilder M, Dumont X, Lundh T, Skerfving S, Bernard A. Associations between proteins and heavy metals in urine at low environmental exposures: evidence of reverse causality. Toxicol Lett. 2012;210:345\u201352.","journal-title":"Toxicol Lett"},{"key":"292_CR48","doi-asserted-by":"publisher","first-page":"2473","DOI":"10.1056\/NEJMra054415","volume":"354","author":"LA Stevens","year":"2006","unstructured":"Stevens LA, Coresh J, Greene T, Levey AS. Assessing kidney function\u2014measured and estimated glomerular filtration rate. N Engl J Med. 2006;354:2473\u201383.","journal-title":"N Engl J Med"},{"key":"292_CR49","unstructured":"National Research Council. Arsenic in drinking water: 2001 update. Washington, DC: The National Academies Press; 2001."},{"key":"292_CR50","unstructured":"Krisher L, Butler-Dawson J, Asensio C, Yoder H, Cruz A, Pilloni D, et al. A total worker health approach to assessing kidney health in sugarcane workers in Guatemala: an opportunity for nutrition intervention. Poster presented at the Third International Workshop on Chronic Kidney Diseases of Uncertain\/Non-Traditional Etiology in Mesoamerica and Other Regions, Costa Rica, 2019."}],"container-title":["Journal of Exposure Science &amp; Environmental Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41370-021-00292-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41370-021-00292-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41370-021-00292-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T23:38:36Z","timestamp":1653003516000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41370-021-00292-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,18]]},"references-count":50,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["292"],"URL":"https:\/\/doi.org\/10.1038\/s41370-021-00292-x","relation":{},"ISSN":["1559-0631","1559-064X"],"issn-type":[{"value":"1559-0631","type":"print"},{"value":"1559-064X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,18]]},"assertion":[{"value":"27 March 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 January 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 February 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The University of Colorado has a memorandum of agreement with Pantaleon, a Guatemala-based agribusiness. Pantaleon provides partial financial support for research through a contract with the university and has provided access to the employees who volunteered to participate in this research project. The University of Colorado employed appropriate research methods in keeping with academic freedom, based conclusions on critical analysis of the evidence, and reported findings fully and objectively. The terms of this arrangement have been reviewed and approved by the University of Colorado in accordance with its conflict of interest policies.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}