{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T08:59:12Z","timestamp":1776329952077,"version":"3.50.1"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T00:00:00Z","timestamp":1738022400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T00:00:00Z","timestamp":1738022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Expo Sci Environ Epidemiol"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1038\/s41370-025-00752-8","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T12:20:28Z","timestamp":1738066828000},"page":"630-631","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["marlod: an R package to model environmental exposure and biomonitoring data with repeated measurements and values below the limit of detection"],"prefix":"10.1038","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6764-8395","authenticated-orcid":false,"given":"I-Chen","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,28]]},"reference":[{"key":"752_CR1","doi-asserted-by":"crossref","unstructured":"Chen IC. marlod: Marginal Modeling for Exposure Data with Values Below the LOD. R package version 0.1.2. 2024. https:\/\/CRAN.R-project.org\/package=marlod.","DOI":"10.32614\/CRAN.package.marlod"},{"key":"752_CR2","first-page":"97","volume":"55","author":"Y Jin","year":"2011","unstructured":"Jin Y, Hein MJ, Deddens JA, Hines CJ. Analysis of lognormally distributed exposure data with repeated measures and values below the limit of detection using SAS. Ann Occup Hyg. 2011;55:97\u2013112.","journal-title":"Ann Occup Hyg"},{"key":"752_CR3","doi-asserted-by":"crossref","unstructured":"Chen IC, Bertke SJ, Estill CF. Compare the marginal effects for environmental exposure and biomonitoring data with repeated measurements and values below the limit of detection. J Expo Sci Environ Epidemiol. 2024;34:1018\u201327.","DOI":"10.1038\/s41370-024-00640-7"},{"key":"752_CR4","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1093\/biomet\/73.1.13","volume":"73","author":"KY Liang","year":"1986","unstructured":"Liang KY, Zeger SL. Longitudinal data analysis using generalized linear models. Biometrika. 1986;73:13\u201322.","journal-title":"Biometrika"},{"key":"752_CR5","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.2307\/1912775","volume":"50","author":"LP Hansen","year":"1982","unstructured":"Hansen LP. Large sample properties of generalized method of moments estimators. Econometrica. 1982;50:1029\u201354.","journal-title":"Econometrica"},{"key":"752_CR6","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1093\/biomet\/87.4.823","volume":"87","author":"A Qu","year":"2000","unstructured":"Qu A, Lindsay BG, Li B. Improving generalised estimating equations using quadratic inference functions. Biometrika. 2000;87:823\u201336.","journal-title":"Biometrika"},{"key":"752_CR7","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1038\/s41370-021-00345-1","volume":"31","author":"IC Chen","year":"2021","unstructured":"Chen IC, Bertke SJ, Curwin BD. Quantile regression for exposure data with repeated measures in the presence of non-detects. J Exposure Sci Environ Epidemiol. 2021;31:1057\u201366.","journal-title":"J Exposure Sci Environ Epidemiol"},{"key":"752_CR8","doi-asserted-by":"publisher","first-page":"1766","DOI":"10.1021\/es00082a001","volume":"24","author":"DR Helsel","year":"1990","unstructured":"Helsel DR. Less than obvious: statistical treatment of data below the detection limit. Environ Sci Technol. 1990;24:1766\u201374.","journal-title":"Environ Sci Technol"},{"key":"752_CR9","doi-asserted-by":"crossref","unstructured":"Chen IC, Bertke SJ, Dahm MM. Quantile regression for longitudinal data with values below the limit of detection and time-dependent covariates\u2014application to modeling carbon nanotube and nanofiber exposures. Ann Work Expo Health. 2024;68:846\u201358.","DOI":"10.1093\/annweh\/wxae068"},{"key":"752_CR10","doi-asserted-by":"publisher","first-page":"309","DOI":"10.2307\/2533336","volume":"51","author":"GMA Fitzmaurice","year":"1995","unstructured":"Fitzmaurice GMA. A caveat concerning independence estimating equations with multiple multivariate binary data. Biometrics. 1995;51:309\u201317.","journal-title":"Biometrics"}],"container-title":["Journal of Exposure Science &amp; Environmental Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41370-025-00752-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41370-025-00752-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41370-025-00752-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T07:50:41Z","timestamp":1751874641000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41370-025-00752-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,28]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["752"],"URL":"https:\/\/doi.org\/10.1038\/s41370-025-00752-8","relation":{},"ISSN":["1559-0631","1559-064X"],"issn-type":[{"value":"1559-0631","type":"print"},{"value":"1559-064X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,28]]},"assertion":[{"value":"18 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 January 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 January 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The author declares no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The findings and conclusions in this report are those of the author and do not necessarily represent the official position of the National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}